prevalence of rhd in shimla town
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PROJECT WORK INDEPARTMENT OFCOMMUNITYMEDICINE
PREVALENCE OF
Rheumatic Heart Disease
in School-Children ofShimla.
2007-2008.
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DEPARTMENT OF Community
Medicine
Indira Gandhi Medical College
Shimla, Himachal
CERTIFICATEDept. of Community Med. IGMC/Batch 2004/ Prevalence of RHD in SchoolChildren of Shimla
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This is to certify that the work contained in
the project entitled Prevalence of Rheumatic Heart
Disease in School-Children of Shimla has been carried
out by Mr. Vaibhav Sharma, Mr. Vikrant Sharma, Mr.
Vikrant Thakur, Mr. Vineet Bhardwaj, Mr. Virat Kuntalam
& Mr. Virender Chauhan of batch 2004 themselves under
one direct supervision and guidance of the undersigned.
The data incorporated in this project is
original and genuine.
Dr. A. K. Bhardwaj
MD, FIPSM, FIPHA
Professor & Head
Dept. of Community Medicine
Indira Gandhi Medical College, Shimla, 171001
Table of ContentsAcknowledgement
5
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Introduction
.6
Why our Study is
Relevant?..............................................................................................................
. 7
Aims and
Objectives
..9
Material and
Methods
..11
Sampling
Technique
12
Modified Jones
Criteria
.13
Tools Used in
Study
.14
Review of
Literature15
Epidemiology
17
Etiopathogenesis
17
Age
Pattern
18
Previous
Studies
.19
Observations
.21
Graphical Representations..
.23
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Summary
.25
Conclusion..
.26
Constrains.
..27
Recommendations.
.28
ANNEXURE
29
Performa
30
Bibliography
32
ACKNOWLEDGEMENT
We have the greatest privilege of expressing out
heartiest thanks to Dr. (Mrs.) Anupam Parashar, Assoc. Professor and
Dr. (Mrs.) Renu P.G. Student, Department of Community Medicine,
Indira Gandhi Medical College, Shimla for their constant
encouragement, invaluable guidance and constructive suggestions
without which this work would have not been successfully completed.
We are also highly obliged and extremely thankful to Dr.
Ashok Kr. Bhardwaj, Prof. & Head Dept. of Community Medicine,
Indira Gandhi Medical College, Shimla for providing us with the
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opportunity to conduct such a study and understand the basics of an
Epidemiological Study. We are also thankful for his expert guidance
and vast and immense practical experience to make our project a
success.
We also extend our thanks to Dr. Anmol Gupta, Assoc.
Professor Dept. of Community Med. IGMC for his invaluable
guidance on project presentation via electronic media.We alsoexpress our heartfelt gratitude to all the faculty members of the Dept.
of Community Medicine who helped us by all possible means.
We would be failing in our duty if we dont thank all thestudents who became our subject of study without whom none of this
would have been possible.
Vaibhav Sharma (0458)
Shimla Vikrant Sharma (0459)
May, 2008. Vikrant Thakur (0460)
Vineet Bhardwaj (0461)
Virat Kuntalam (0463)Virender Chauhan (0464)
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INTRODUCTION
INTRODUCTION
Rheumatic Heart Disease (RHD) is a noncommunicable but crippling disease, it is the cardiac
manifestation of Rheumatic Fever, which is a febrile disease
affecting connective tissue particularly in heart, joints,
subcutaneous tissue in the form of sub cutaneous nodules and
rarely does it affect the CNS. Initiated by infection of throat
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by a Group A beta haemolytic streptococcus (GABHS), the
heart lesions are the only one which can lead to chronic
illness, disability and early death. Prognosis depends on
seriousness of Carditis and frequency of recurrent attacks.
Most of the time, it is preceded by an episode of sore throat.
RHD is a world wide problem especially in
population living in over crowded and low socioeconomic
circumstances. It is especially prevalent in school children
which happen to be the most vulnerable group. It can be
called as profession hazard of school.
Why our study is relevant?
1. Crippling our Future generation
2. Catches them young
3. RHD Constitutes 20-25% of hospital admission due toCVD.
4. Prevalence low but Significant Morbidity & Mortality.
5. School going Children constitutes 20-25% of total
population of India.
6. Average age at the time of death due to RHD is 35 yrs.
An epidemiological study of RHD in school going
children in hilly area was done which gave the prevalence of
2.98 per thousand with no significant difference between the
age groups of 5-10 and 11-16 or in either sex.
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With the advent of Penicillin and newer drugs,
incidence and prevalence, mortality & morbidity associated
with RHD has considerably reduced.
Rheumatic Fever being an occupational disease of
school children, it can effectively be screened.
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AIMS
&
OBJECTIVES
Aims and Objectives
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1. To determine the prevalence of RHD among
school children of Shimla.
2. To study the relation of RHD with factors likeage and sex.
3. To learn the basics of conducting an
epidemiological study.
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Material
&
Methods
Materials and methods
Geographical Area-
Himachal Pradesh comprises of varied
geographical terrains like plains, hills, valleys and mountains.
The state has area of 55673 sq. km. and is divided into 12
districts.
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Shimla is capital of H.P. situated at an altitude
of 2130 mts. With an area of 18 sq. km. town has temperature
variation in winter (max. 18 degrees, min. -1 degrees) and
summer (33 degrees max. and min. of 1degree)
Sampling technique
In the cross sectional study, a stratified
random sample of 217 children was selected from one school
in the age group of 5 to 15 years of age.
Way of conducting survey
Survey was conducted by the way of
questionnaires. The questionnaire was structural already andthe questions in it were close ended questions which had their
answers in only YES or NO.
Criteria for study of RHD
According to modified Jones criteria, the
clinical features of rheumatic fever are divided into major and
minor manifestations which lead to diagnosis of rheumatic
fever.
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For Diagnosis of Rheumatic Heart Disease
Fig. Showing the Modified Jones Criteria for Diagnosis of RHD
Tools of methods used in the study
The school was visited with prior approval of
the principal and purpose and nature of study were already
discussed with her.
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Children were randomly selected from classes and
were examined after a detailed history was taken on the basis
of pre-formed questionnaire.
Then cardiovascular examination was done and
murmurs were auscultated which was done in erect, left lateral
and recumbent positions.
There was only one case of murmurs with
parasternal heave and was referred to Dept. of Cardiology
IGMC Shimla.
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REVIEW OF
LITERATURE
REVIEW OF LITERATURE
Historically the disease was recognised by Hippocrates who
categorically stated that:
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child who has pain in legs is going to become short of
breath.
The name rheumatic was given by
Haygarth in 1805 A.D. Its association to heart was established
in 1800A.D. by Pit Cairn and Jenner.
Before Second World War, relatively little
was understood about epidemiology and pathogenesis of these
infections and chains sequel. The lab studies of Rebecca
Lancefield and those by Dr. Rammal Kamp and his colleaguesmade significant contribution to the understanding and control
of RHD. Only studies on repository penicillin was another
major achievement causing a significant decrease in incidence
of RF/RHD. However, since mid 1980s with the resurgence of
severe GABHS infections and their suppurative and non-
suppurative sequel, the disease reoccupied its previous statusin epidemiologic and clinical studies.
Currently success has been achieved not only
in accurate diagnosis of GABHS in infection but also in
secondary & primary prevention of RHD.
EPIDEMIOLOGY
Rheumatic fever or RHD presents a problem
in all parts of world especially in developing countries. RF is
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the most common cause of heart disease in the 5-30 yrs age
group throughout the world. Rheumatic Heart Disease
constitutes 30-35% of hospital admission due to Cardio-
Vascular Diseases.
ETIOPATHOGENESIS
The disease is an example of molecular mimicry type ofautoimmunity. The complete pathogenesis of this disease is
unknown. There are three main factors.
1. Group A beta-haemolytic streptococcal infection of
upper respiratory tract.
2. Specific susceptibility of human host.
3. Environmental factors like altitude, crowding
&dampness.
This disease is triggered by infection with
group A beta haemolytic streptococci & the serotype that
has attracted special emphasis is M- type 5 which is
frequently associated with RF.
ETIOPATHOGENESIS
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Fig: Showing the Etiopathogenesis of RF
AGE PATTERN
RHD is common in children particularlyschool going children i.e. 5-15 yrs. With almost equal
incidence among age groups 5-10 years and 11-16 years.
PREVIOUS STUDIES IN INDIA
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There have been many studies on this issue in
India in past but few major ones are worth to mention here.
As per the study conducted by Indian Council of Medical
Research (ICMR), the prevalence of RHD was found to be
2.1/1000 to 11/1000 in different regions of the country.
Average prevalence was around 7/1000 with no male or
female predilections.
One of the largest studies conducted so far on
this subject is the study conducted by Dept. of Cardiology,
Christian Medical College (CMC), Vellore. The study
sample consisted of more than 2 Lakh (n = 229,829) and in
that study prevalence was found to be 0.68/1000. Thereason for such a low prevalence was that the final
evaluation was done by the experts after echocardiography
which omitted the possible false positive cases.
PREVIOUS STUDIES HIMACHAL
PRADESH
Few studies have been done in hilly areas of
North India and they have shown progressive decline in the
prevalence of RHD. A study conducted in and around
Shimla in 1994 showed the prevalence of 2.98/1000.
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Earliest study in this region of country dates
back to 1956 when prevalence was found to be 3.9/1000
which happen to be the highest reported prevalence rate
through out the country at that time.
Another study was conducted in 1998 by
Dept. of Community Medicine, IGMC, Shimla reported a
prevalence rate of 3.627/1000.
As per the ongoing study being conducted byDept. of Community Medicine, IGMC, Shimla so far only
one case of RHD is reported in approximately 5000 student
surveyed.
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OBSERVATIO
NS
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OBSERVATIONS
Out of 217 students studied there were 91 Girls and 126
Boys. All were in the age Group of 5-11 years.
Out of these, 23 (10.5%) reported to have cough at the
time of study. 16 (7.4%) of them complained of having sore
throat at that time or in the passed week.
Shortness of Breath was reported by 14 students i.e.5.1%. 8 students said that they have some degree of chest pain
off and on. This group comprised 3.7% of the total.
7 students complained of occasional episodes of syncope
i.e. approx 3% student have had syncope.
Joint Pains were reported by 5 students (2.3%).
Other complaints reported by students were Pain
abdomen (2), giddiness etc. which were largely irrelevant to
our study.
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Fig. Showing findings in the form of Bars
Most of the children reported with cough and
sore throat that can be explained if we keep in mind thetime of study. The study was conducted in the month of
Feb. when the weather here was freezing.
Findings of cyanosis on physical examination
can also be attributed to cold surroundings prevalent at the
time of study.
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Fig. Showing the observations in the form of Pie.
Fig. Showing the findings on GPE
In the above graph, the most frequent finding is shown by the complete
cone while rest of the cones show the frequency of events relative to the
most frequent finding.
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SUMMARY
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SUMMARY
A stratified sample of 217 school children in
the age group 5 years to 11 years was taken in a school in
Shimla town. Since the main motive was to learn the basics
involved in an epidemiological study and also there was a
lot of constrains in the form of money, material and time.
Therefore, such a small sample was chosen. Also it was the
month of Feb. when most of the schools were closed.
Percentages of absentees were 5 percent.
In our study, no case was found to be positive
for Rheumatic Heart Disease (RHD) on clinical grounds,
though lot of positive findings were found related to
cardiovascular system.
CONCLUSION
Clinical Examination as the method of
identifying a case of Rheumatic Heart Disease is neither
very specific nor it is sensitive. Parents were reluctant to
get their child evaluated by the expert. There was no case of
Rheumatic Heart Disease in our study. Pallor was positive
in significant proportion (17%) of the subjects.
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CONSTRAINTS
Like any other epidemiological study, our
study too was limited by constraints of money, material and
time. Other than these the major limitations in our studies
were:
1. Inadequate sample size combined with a very low
prevalence.
2. Selection bias i.e. may be some of the students who were
suffering from RHD might not have attended the school
owing to their illness and thus were left out.
3. Our limited knowledge in the concerned fields. We are
students only.
4. Compliance of children was also a limitation, but this
was limited only to the younger age groups.5. Reliability of the history given.
6. Clinical features of the disease are not very specific and
there is wide range of overlap.
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RECOMMMENDATIONS
Based on our findings we make following
recommendations in the benefit of health of school
children:
1. Teachers are recommended to remain ultra vigilant for
the warning symptoms of the disease.
2. Practical suggestions like opening certain windows for
effective cross ventilation are advocated. But that is bit
difficult to follow especially in the winters.
3. We also suggest that at least one parents-teacher meeting
should be held every quarterly to discuss the progress of
their wards in the fields of studies and health as well.
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ANNEXURE
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PERFORMA
Name: ____________________ Age: ____Sex: __
School: __________________________________
Address: ____________________
_____________________
HISTORY:
H/o Recurrent Sore Throat Yes/No
H/o Chest Pain Yes/No
H/o Palpitation Yes/No
If Yes, Is it aggravated by activities? Yes/No
Is it even present at rest? Yes/No
H/o Syncope (any postural association) Yes/No
H/o Fever/Body aches/Chills/Rigors/Sweats Yes/No
H/o fleeting joint pains Yes/No
H/o abnormal movements of limbs Yes/No
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H/o any penicillin prophylaxis for RHD Yes/No
(If Yes then when and how long?)
H/o Shortness of Breath Yes/No
H/o PND/ Orthopnoea Yes/No
H/o Cough Yes/No
H/o Haemoptysis Yes/No
H/o Discharge from Ear/Ear aches Yes/No
Any Significant past History Yes/No
GENERAL PHYSICAL EXAMINATION:
Pallor: Yes/No
Icterus: Yes/No
Cyanosis: Yes/No
Clubbing: Yes/No
Lymphadenopathy Yes/No
JVP: Raised/Not Raised
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Detailed CVS Examination:
Inspection:
Chest Symmetry:
Apex Beat:
Thrill:
Palpation:
Palpable Thrill/Murmur:
Parasternal Heave:
Percussion:
Cardiac Dullness:
Auscultation:
1st and 2nd heart sounds:
Murmur:
Any added Sounds:
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BIBLIOGRAPHY
1. Thakur JS, Negi PC, Ahluwalia SK, Vaidya NK. Epidemiological
survey of RHD among school children in Shimla hills of Northern
India: Prevalence and Risk Factors; Journal of Epidemiology &
Community Health 1996 Feb; 50(1); 62-67.
2. RF & RHD: Report of a WHO study Group. WHO Tech Rep Ser No.
764, 1988.
3. Jose VJ, Gomathi M. Declining Prevalence of Rheumatic Heart
Disease in Rural School Children in India: 20012002;Indian Heart J2003; 55: 158160.
4. Lalchandani A, Kumar HRP, Alam SM. Prevalence of rheumatic fever
and rheumatic heart disease in rural and urban school children of
district Kanpur [Abstract].Indian Heart J2000; 52: 672.
5. K Rajesh, Controlling RHD in Developing Countries; Public Health
Practice; 1995.
6. Mahajan BK, 5th edition Methods in Biostatistics 1991. New Delhi:
Jaypee Brothers, 87-101.
7. Park K, 19th edition Parks Textbook of Preventive and Social
Medicine 2007. Jabalpur: M/s Banarsidas Bhanot Publishers; 315-318,
696-706.