press: unc medical researchers unexpectedly grow bone from stem cells

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Page 1 of 2 NEWS RELEASE FOR IMMEDIATE RELEASE FOR MORE INFORMATION, CONTACT: Irma Calderón Woodruff at 210-410-1214 Growing New Bone UNC Medical Researchers Unexpectedly Grow Bone From Stem Cells Already Underway in San Antonio! San Antonio, TX, Thursday, December 10, 2015 – Medical researchers surprised themselves when they discovered a new way to convert stem cells into bone. To understand the significance of their finding, a basic understanding of current stem cell therapy is important. Our bodies are composed of billions of different, specialized cells. Each one has its own role to fill in our organs, tendons, joints, muscles, etc. Stem cells are unspecialized. They will divide to produce more stem cells but do not take on a specialized task. Under certain conditions, however, stem cells can be induced into becoming a tissue-specific, specialized cell. Most people are aware of embryonic stem cells and the controversy that surrounds them. However, the Stem Cell Orthopedic Institute uses somatic stem cells, also known as adult stem cells. Everyone has unspecialized cells found throughout the body, inside tissue and organs. These cells exist to produce more cells. They aid your body by regenerating damaged tissue and replenishing dying cells. In recent years, adult stem cells have launched the innovative field of stem cell therapy or regenerative medicine, which focuses on regrowth and repair of old damage. Injecting a patient’s adult stem cells into a damaged area in their body can accelerate the natural healing process by greatly increasing the regenerative abilities that specific location. Stem cell therapy is currently used to treat a variety of ailments, such as osteoarthritis, hip pain, knee pain, degenerative disc disease, and rotator cuff tears/tendinosis.

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San Antonio, TX, Thursday, December 10, 2015 – Medical researchers surprised themselves when they discovered a new way to convert stem cells into bone.

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Page 1: Press: UNC Medical Researchers Unexpectedly Grow Bone From Stem Cells

Page 1 of 2

NEWS RELEASE FOR IMMEDIATE RELEASE FOR MORE INFORMATION, CONTACT: Irma Calderón Woodruff at 210-410-1214

Growing New Bone

UNC Medical Researchers Unexpectedly Grow Bone From Stem Cells

Already Underway in San Antonio!

San Antonio, TX, Thursday, December 10, 2015 – Medical researchers surprised themselves when they

discovered a new way to convert stem cells into bone.

To understand the significance of their finding, a basic understanding of current stem cell therapy is

important. Our bodies are composed of billions of different, specialized cells. Each one has its own role

to fill in our organs, tendons, joints, muscles, etc. Stem cells are unspecialized. They will divide to

produce more stem cells but do not take on a specialized task. Under certain conditions, however, stem

cells can be induced into becoming a tissue-specific, specialized cell.

Most people are aware of embryonic stem cells and the controversy that surrounds them. However, the

Stem Cell Orthopedic Institute uses somatic stem cells, also known as adult stem cells. Everyone has

unspecialized cells found throughout the body, inside tissue and organs. These cells exist to produce

more cells. They aid your body by regenerating damaged tissue and replenishing dying cells.

In recent years, adult stem cells have launched the innovative field of stem cell therapy or regenerative

medicine, which focuses on regrowth and repair of old damage. Injecting a patient’s adult stem cells into

a damaged area in their body can accelerate the natural healing process by greatly increasing the

regenerative abilities that specific location. Stem cell therapy is currently used to treat a variety of

ailments, such as osteoarthritis, hip pain, knee pain, degenerative disc disease, and rotator cuff

tears/tendinosis.

Page 2: Press: UNC Medical Researchers Unexpectedly Grow Bone From Stem Cells

Page 2 of 2

Medical science is often a slow, lengthy process wherein researchers methodically work through every

aspect of a problem in controlled conditions. Regenerative medicine, however, is a very new field and,

when exploring uncharted territory, surprises do occur.

The medical researchers at University of North Carolina at Chapel Hill School of Medicine experienced

such a surprise recently when applying cytochalasin D, a substance found in mold, to stem cells. They

expected the cells to turn into fat. Instead, they become bone.

“It goes against everything in the literature,” says

Professor Janet Rubin. The team expected the cells

to lose their ability to form bone but the exact

opposite occurred.

“And the bone forms quickly,” states Rubin. “The data and images are so clear; you don’t have to be a

bone biologist to see what the cytochalasin D does in one week in a mouse.”

Their research was published in the journal Stem Cells and can be found online.

It isn’t difficult to imagine the far reaching impact that this discovery could have. Osteoporosis and low

bone mass affects around 54 million Americans. Senior citizens are especially at risk of serious

complications. Osteoporosis symptoms can be easy to overlook as a natural part of aging but the impact

on a senior’s health can be dramatic. 20% of seniors who break a hip die within a year, either due to the

broken bone itself or complications from the surgery used to repair it. The ability to regrow lost bones

would dramatically improve and frequently save lives.

Is stem cell therapy right for you? To schedule a medical evaluation with the Stem Cell Orthopedic

Institute of Texas, please call (210) 293-3136. Courteous Patient Advocates are standing by to answer

your questions. Reporters who would like interviews should call Irma Calderón Woodruff at (210) 410-

1214.