presented by halle moore at 2014 asco annual meeting

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Prevention of Early Menopause Study<br />(POEMS)-S0230<br /> Phase III trial of LHRH analog during chemotherapy to reduce ovarian failure in early stage, hormone receptor-negative breast cancer: an international Intergroup trial of SWOG, IBCSG, ECOG, and CALGB (Alliance) Presented By Halle Moore at 2014 ASCO Annual Meeting

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Prevention of Early Menopause Study(POEMS)-S0230 Phase III trial of LHRH analog during chemotherapy to reduce ovarian failure in early stage, hormone receptor-negative breast cancer: an international Intergroup trial of SWOG, IBCSG, ECOG, and CALGB (Alliance). - PowerPoint PPT Presentation

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Page 1: Presented By Halle Moore at 2014 ASCO Annual Meeting

Prevention of Early Menopause Study<br />(POEMS)-S0230<br /> Phase III trial of LHRH analog during chemotherapy to reduce ovarian failure in early stage, hormone receptor-negative breast cancer: an international Intergroup trial of SWOG, IBCSG, ECOG, and CALGB (Alliance)

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 2: Presented By Halle Moore at 2014 ASCO Annual Meeting

Background

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 3: Presented By Halle Moore at 2014 ASCO Annual Meeting

Ovarian Protection with LHRH analog

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 4: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS/S0230 Schema

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 5: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Objectives and Endpoints

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 6: Presented By Halle Moore at 2014 ASCO Annual Meeting

Goserelin Administration

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 7: Presented By Halle Moore at 2014 ASCO Annual Meeting

Patient Eligibility

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 8: Presented By Halle Moore at 2014 ASCO Annual Meeting

Statistical Considerations

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 9: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Consort Diagram

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 10: Presented By Halle Moore at 2014 ASCO Annual Meeting

Patients

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 11: Presented By Halle Moore at 2014 ASCO Annual Meeting

Endocrine Toxicity

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 12: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Ovarian Failure

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 13: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Secondary Ovarian Outcomes

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 14: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Pregnancy

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 15: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Disease Free Survival

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 16: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Overall Survival

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 17: Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 18: Presented By Halle Moore at 2014 ASCO Annual Meeting

Conclusions

Presented By Halle Moore at 2014 ASCO Annual Meeting

Page 19: Presented By Halle Moore at 2014 ASCO Annual Meeting

Acknowledgements

Presented By Halle Moore at 2014 ASCO Annual Meeting