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SMARSUPIALIZZAZZIONE DEL CATETERE PERITONEALE

The Moncrief-Popovich catheter A new peritoneal access technique for patients on peritoneal dialysis

Moncrief JW Popovich RP ASAIO J 1993 Jan-Mar 39(1) 62-5

bull There was a rate of one exit site infection every 1257 patients-months

bull The Moncrief-Popovich catheter and implantation technique result in a substantial decrease in the incidence of peritonitis for patients using the standard spike exchange system

Modificazioni del catetere marsupializzato

Moncrief-Popovich catheter and technique

Subcutaneous burial of the external segment of the catheter to prevent colonization of the catheter by skin bacteria and promote attachment of the cuff to the tissue prior to exteriorization has been described and recently tested by several experienced clinicians

with encouraging results

The initial reports by the developers claimed a reduction in the rate of peritonitis and

colonization of bacterial biofilms in the catheter segments between the two cuffs

However a controlled randomized study failed to confirm these claims14 A possible reason for the failure to reduce the incidence of infectious complications may be the inability of the body to provide an effective ldquosealrdquo around the external cuff Therefore upon exteriorization of the catheter the process of healing starts all over again

Prischl et al have also reported a high incidence of seromas subcutaneous hematomas and fibrin thrombi postoperatively with this technique15

analisi SWOT

StrenghtsbullTempi intervento chirurgico posizionamento non incrementatibullSchema corporeo immodificatobullPaziente ldquoambulatorialerdquobullIncremento pool Pazienti peritonealebullBreak-in e volumi intraaddominalibullRiduzione complicanze meccaniche peri-inserzionebullSeparazione intervento da addestramento

WeaknessesbullTecnica chirurgica nuova (curva di apprendimento)bullIntervento chirurgico in due tempibullNon operativitagrave sul catetere impiantatobull impianto precoce

OpportunitiesbullDialisi incrementalebullReclutamento pazienti pre-dialisibullReclutamento pazienti acutibullRiduzione incidenza CVC

ThreatsLetteraturaAmbiente interno

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

The Moncrief-Popovich catheter A new peritoneal access technique for patients on peritoneal dialysis

Moncrief JW Popovich RP ASAIO J 1993 Jan-Mar 39(1) 62-5

bull There was a rate of one exit site infection every 1257 patients-months

bull The Moncrief-Popovich catheter and implantation technique result in a substantial decrease in the incidence of peritonitis for patients using the standard spike exchange system

Modificazioni del catetere marsupializzato

Moncrief-Popovich catheter and technique

Subcutaneous burial of the external segment of the catheter to prevent colonization of the catheter by skin bacteria and promote attachment of the cuff to the tissue prior to exteriorization has been described and recently tested by several experienced clinicians

with encouraging results

The initial reports by the developers claimed a reduction in the rate of peritonitis and

colonization of bacterial biofilms in the catheter segments between the two cuffs

However a controlled randomized study failed to confirm these claims14 A possible reason for the failure to reduce the incidence of infectious complications may be the inability of the body to provide an effective ldquosealrdquo around the external cuff Therefore upon exteriorization of the catheter the process of healing starts all over again

Prischl et al have also reported a high incidence of seromas subcutaneous hematomas and fibrin thrombi postoperatively with this technique15

analisi SWOT

StrenghtsbullTempi intervento chirurgico posizionamento non incrementatibullSchema corporeo immodificatobullPaziente ldquoambulatorialerdquobullIncremento pool Pazienti peritonealebullBreak-in e volumi intraaddominalibullRiduzione complicanze meccaniche peri-inserzionebullSeparazione intervento da addestramento

WeaknessesbullTecnica chirurgica nuova (curva di apprendimento)bullIntervento chirurgico in due tempibullNon operativitagrave sul catetere impiantatobull impianto precoce

OpportunitiesbullDialisi incrementalebullReclutamento pazienti pre-dialisibullReclutamento pazienti acutibullRiduzione incidenza CVC

ThreatsLetteraturaAmbiente interno

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Modificazioni del catetere marsupializzato

Moncrief-Popovich catheter and technique

Subcutaneous burial of the external segment of the catheter to prevent colonization of the catheter by skin bacteria and promote attachment of the cuff to the tissue prior to exteriorization has been described and recently tested by several experienced clinicians

with encouraging results

The initial reports by the developers claimed a reduction in the rate of peritonitis and

colonization of bacterial biofilms in the catheter segments between the two cuffs

However a controlled randomized study failed to confirm these claims14 A possible reason for the failure to reduce the incidence of infectious complications may be the inability of the body to provide an effective ldquosealrdquo around the external cuff Therefore upon exteriorization of the catheter the process of healing starts all over again

Prischl et al have also reported a high incidence of seromas subcutaneous hematomas and fibrin thrombi postoperatively with this technique15

analisi SWOT

StrenghtsbullTempi intervento chirurgico posizionamento non incrementatibullSchema corporeo immodificatobullPaziente ldquoambulatorialerdquobullIncremento pool Pazienti peritonealebullBreak-in e volumi intraaddominalibullRiduzione complicanze meccaniche peri-inserzionebullSeparazione intervento da addestramento

WeaknessesbullTecnica chirurgica nuova (curva di apprendimento)bullIntervento chirurgico in due tempibullNon operativitagrave sul catetere impiantatobull impianto precoce

OpportunitiesbullDialisi incrementalebullReclutamento pazienti pre-dialisibullReclutamento pazienti acutibullRiduzione incidenza CVC

ThreatsLetteraturaAmbiente interno

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Moncrief-Popovich catheter and technique

Subcutaneous burial of the external segment of the catheter to prevent colonization of the catheter by skin bacteria and promote attachment of the cuff to the tissue prior to exteriorization has been described and recently tested by several experienced clinicians

with encouraging results

The initial reports by the developers claimed a reduction in the rate of peritonitis and

colonization of bacterial biofilms in the catheter segments between the two cuffs

However a controlled randomized study failed to confirm these claims14 A possible reason for the failure to reduce the incidence of infectious complications may be the inability of the body to provide an effective ldquosealrdquo around the external cuff Therefore upon exteriorization of the catheter the process of healing starts all over again

Prischl et al have also reported a high incidence of seromas subcutaneous hematomas and fibrin thrombi postoperatively with this technique15

analisi SWOT

StrenghtsbullTempi intervento chirurgico posizionamento non incrementatibullSchema corporeo immodificatobullPaziente ldquoambulatorialerdquobullIncremento pool Pazienti peritonealebullBreak-in e volumi intraaddominalibullRiduzione complicanze meccaniche peri-inserzionebullSeparazione intervento da addestramento

WeaknessesbullTecnica chirurgica nuova (curva di apprendimento)bullIntervento chirurgico in due tempibullNon operativitagrave sul catetere impiantatobull impianto precoce

OpportunitiesbullDialisi incrementalebullReclutamento pazienti pre-dialisibullReclutamento pazienti acutibullRiduzione incidenza CVC

ThreatsLetteraturaAmbiente interno

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

analisi SWOT

StrenghtsbullTempi intervento chirurgico posizionamento non incrementatibullSchema corporeo immodificatobullPaziente ldquoambulatorialerdquobullIncremento pool Pazienti peritonealebullBreak-in e volumi intraaddominalibullRiduzione complicanze meccaniche peri-inserzionebullSeparazione intervento da addestramento

WeaknessesbullTecnica chirurgica nuova (curva di apprendimento)bullIntervento chirurgico in due tempibullNon operativitagrave sul catetere impiantatobull impianto precoce

OpportunitiesbullDialisi incrementalebullReclutamento pazienti pre-dialisibullReclutamento pazienti acutibullRiduzione incidenza CVC

ThreatsLetteraturaAmbiente interno

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intra-addominali

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Break-in

Cheng 1996

86 cateteri tecnica chirurgicabull 40 -gt break-in HD (gruppo A)bull 60 subito ( B)

Follow-up di 6 mesi -lrsquoincidenza di leakage era significativamente piugrave alta nel gruppo B (0 vs 13 p lt 005) tra i pazienti diabetici (71 vs 22 p lt 005) - pazienti positivi per leakage piugrave alta incidenza di esteriorizzazione della cuffia esterna (57 vs 7 p lt 0005)

Jo 2007

Studio prospettico osservazionale su 51 pazienti tecnica percutanea modificata ed il suo utilizzo avveniva senza un periodo di break-in

(chirurgico fino alla fascia anteriore del muscolo retto poi per raggiungere la cavitagrave peritoneale attraverso il muscolo si utilizzavano dei dilatatori la cuffia interna veniva ancorata con una borsa di tabacco sul versante muscolare della fascia esterna del retto)

rarr 2 di leakage e 6 di dislocazione

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Strenghts

Tempi intervento chirurgico posizionamento non incrementati

Schema corporeo immodificato

Paziente ldquoambulatorialerdquo

Incremento pool Pazienti peritoneale

Break-in e volumi intraaddominali

Riduzione complicanze meccaniche peri-inserzione

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

malposizionamentodislocazione

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Casistica 12236 rarr 5

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

How to start the late referred ESRD patient urgently on chronic APD

Povlsen JV Ivarsen P

NDT 2006 Jul 21 Suppl 2 ii56-9

Retrospective study describing how acute APD was initiated using a standard prescription for a 12 h overnight APD in the supine position right after (lt24 h) PD catheter placement and comparing short-term (3 months)

The number and type of infectious complications were equal in both the groups

The total number of mechanical complications was significantly higher in the acute group compared with the planned group (P lt 005)

Consequently the need for surgical replacement of catheters was also significantly higher in the study group (P lt 002)

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Fluoroscopic placement of peritoneal dialysis catheters a harvest of the low-hanging fruits

Crabtree JH PDI 2008 Mar-Apr28(2)134-7

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

bull Separazione intervento da addestramento

Strenghts

bullTempi intervento chirurgico posizionamento non incrementati

bullSchema corporeo immodificato

bullPaziente ldquoambulatorialerdquo

bullIncremento pool Pazienti peritoneale

bullBreak-in e volumi intraaddominali

bullRiduzione complicanze meccaniche peri-inserzione

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Weaknesses

bull Tecnica chirurgica nuova (curva di apprendimento)

bull Intervento chirurgico in due tempi

bull Non operativitagrave sul catetere impiantato

bull impianto precoce

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Opportunities

bull Dialisi incrementale

bull Reclutamento pazienti pre-dialisi

bull Reclutamento pazienti acuti

bull Riduzione incidenza CVC

bull Letteratura

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Opportunities

bull Vascular catheter use was predictive of mortality

bull Both AVG and vascular catheter use in incident hemodialysis patients are associated with significant excess of total mortality

Vascular access and all-cause mortality a propensity score analysis

Polkinghorne KR J Am Soc Nephrol 2004 Feb15(2)477-86SourceThe Australian and New Zealand Dialysis and Transplant Association (ANZDATA) Registry

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Moncrief-Popovich technique is an advantageous method of peritoneal dialysis catheter implantation

Brum S NDT 2010 Sep25(9)3070-5

467 catheters rarrmini-laparotomy with MP method in 180 (385)

The MP technique was significantly associated with

bull a lower rate of early exit-site infection (ESI) (P = 002)

bull lower rate of leak (P lt 00001)

bull lower rate of obstruction (P = 0034) in spite of prolonged break-in (median 55 days range 0-991 days)

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Peritoneal dialysis catheter embedment surgical considerations expectations and

complicationsCrabtree JH Burchette RJ Am J Surg 2013 Jul 12

A total of 84 catheters including conventional and extended catheters were embedded and externalized during the study period Factors influencing duration of embedment functionality upon externalization and long-term outcomes were analyzed

Mean duration of embedment was 139 months (median 94 range 5 to 685) Immediate function was exhibited in 857 of catheters Employing laparoscopic revision 988 of embedded catheters were successfully used for peritoneal dialysis

Conclusion Catheters can be embedded for prolonged periods and still result in functional dialysis access when needed Complications are few and easily managed

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Threats

bull Letteratura

bull Ambiente interno

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Abdominal visceral perforation by buried peritoneal dialysis catheters Cause or coincidenceYao J1 Witherspoon L1 McCormick BB2 Belanger E3 Warren JE1

Semin Dial 2018 Mar 7 doi101111sdi12690

Asymptomatic Peritoneal Leukocytosis After Exteriorization of Buried Peritoneal Dialysis Catheters A Case SeriesRandah Dahlan1 Joanne M Bargman2 Mohan Biyani1 Susan Lavoie1 and Brendan B McCormick1

Perit Dial Int 2015 Jan-Feb 35(1) 103ndash105

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Standard insertion with resting but no subcutaneous burying of the catheter versus implantation and subcutaneous burying was not associated with a significant reduction in peritonitis rate exit-sitetunnel infection rate or all-cause mortality

Catheter type placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients

Strippoli GF Tong A Johnson D Schena FP Craig JC

SourceCochrane Renal Group Centre for Kidney Research NHMRC Centre for Clinical Research Excellence in Renal Medicine

Childrens Hospital at Westmead Locked Bag 4001 Westmead 2145 NSW Australia

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

bull Early initiation of CAPD with surgically implanted Tenckhoff catheters is feasible and safe

bull Shorter break-in periods are not associated with more catheter-related complications

bull The data from our peritoneal dialysis population suggest that early initiation is not associated with an increased number of complications

Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters

Yang YF PDI 2011 Sep-Oct31(5)551-7

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Subcutaneous burying of the distal catheter segment prior to starting

PD does not reduce the risk of contracting peritonitis or exit-site infection

A prospective randomized study of the effect of a subcutaneously buried peritoneal dialysis catheter technique versus standard technique on the incidence of peritonitis and exit-site infection

Danielsson A PDI 2002 Mar-Apr22(2)211-9

60 randomized patients rarr 30 MP 66 patients (NS group) were not randomized as they had to start PD within 1-2 weeks after implantation

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Prolonged duration of peritoneal dialysis catheter embedment does not lower the catheter success rate

Elhassan E PDI 2011 Sep-Oct31(5)558-64

bull 134 catheters were implanted and externalized rarr 122 catheters

bull break-in 405 days (range 2 - 788 days)

bull 13 catheters (107) lacked patency on externalization because of fibrin plug or kinking (n = 10) or omental wrap (n = 3) (12 -gt laparoscopically

bull Other complications incision site and tunnel infection in 2 cases (16) exit-site leak in 2 cases (16) and coagulase-negative staphylococcal peritonitis in 1 case (08)

Duration of catheter embedment before externalization did not affect catheter survival

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Time between peritoneal dialysis catheter insertion and use

Elhassan E Contribut Nephrol 2012178228-31

Such advantages may encourage wider use of the Moncrief-Popovich technique in PD units Observational studies indicate that the duration of catheter embedment between implantation and externalization does not appear to affect catheter survival

Larger studies are still awaited to further explore the optimum duration of embedment

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

n Ds range

cateteri impiantati 236

pazienti 234

Etagrave anagrafica inserzione (anni)(mediana)

73 1421 25-89

Intervallo posizionamento-smarsupializzazione (giorni) (mediana)

92 376 8- 2649

Sopravvivenza catetere (giorni) (mediana)

620 624 6-2702

Casistica (2007-2018)

32

14

decesso

infezione

altro

trapianto

trasferimento

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

Pazienti

- Uomini

- Donne

- Totale

141 (603)

93 (397)

234

Etagrave media

- Della popolazione in studio

- Allrsquoinserimento del CP73 anni (DS 15)

66 anni (DS 14)

Patologia di base

- Nefroangiosclerosi

- Glomerulonefriti

- Diabete Mellito

76 (32)

50 (214)

39 (167)

Comorbilitagrave

- Ipertensione

- Cardiopatia

- AOCPVasculopatia

180 (77)

100 (43)

70 (30)

Clearance media (creatinina-urea)

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP12 mlmin (max 25 ndash min 4 mlmin)

8 mlmin (max 23 ndash min 1 mlmin)

Diuresi residua media

- Allrsquoinserimento del CP

- Alla smarsupializzazione del CP1930 mldie

1860 mldie

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait

ldquoNon possiamo pretendere che le cose cambino se continuiamo a fare le stesse coserdquo

-Albert Einstein -

stefanomanganoasst-larianait