A NEW ARTICLE TYPE AND PLATFORM FOR THE

PUBLICATION OF ANTIBODY VALIDATIONS

MICHAEL MARKIEAssociate Publisher, F1000Research

@mmmarksman

f1000research.com@f1000research

WHAT PUBLISHING SHOULD BE:

A TYPICAL F1000RESEARCH ARTICLE PAGE:

THE NEED FOR AN ANTIBODY VALIDATION ARTICLE TYPE?

• Antibodies are among the most common reagents used in research and clinical laboratories

• There is lack of standard guidelines when it comes to manufacturing, validating, and using antibodies

In an ideal world researchers would like:

• Confidence in a particular antibody before it is purchased

• Confidence in the specificity, selectivity and reproducibility

• Information based on actual use cases from the scientific community

TRYING TO TACKLE THE PROBLEM

1. Viability: costs, incentives, interested parties, potential conflicts

2. Editorial Considerations:

- discussed different types of validations that can be performed - creating a set of flexible guidelines for all validations- Identifying an editorial board

3. Dissemination: creating a permanent, discoverable venue for articles

The Antibody Validation article

... INTRODUCING THE ANTIBODY VALIDATION COLLECTION

So far we have created:

• A set of author guidelines for validation articles to be published under the F1000Research ‘Research Note’ article type

• A diverse editorial board with a mixture of industry and academia expertise

• A dedicated F1000Research Antibody Validation Collection to host all of the antibody validation articles we receive.

ANTIBODY COLLECTION PAGE

f1000research.com/article-collections/antibody-validation

GUEST EDITORS AND EDITORIAL BOARD

Guest Editors: Andrew Chalmers (CiteAb) Matt Helsby (CiteAb) Mei Leung (St John’s Laboratory)

ARTICLE GUIDELINES

bit.ly/F1R-AV-Guidelines

The article guidelines we devised can be found here online:

There are some here too, please take one!

Your thoughts are more than welcome.

THE NEXT STEPS

Promoting the new article type and collection to the wider community

Instilling the idea that publishing validations is beneficial and worthwhile

Looking at ways in which we can help grow the content of the collection

WE WANT TO ENCOURAGE INPUT FROM THE COMMUNITY

Feedback on what we have done to date

Contribute – input will be happily received!

How do we best reach the community?

Are their any potential pitfalls?