Letter from the PresidentIt is my pleasure to welcome you to the Northeast Regional Chapter of

the Society of Toxicology (NESOT). The mission of the NESOT chapter is in advancing science to enhance human, animal, and environmental health,

and to enhance the SOT mission of dedication to creating a safer and healthier world by advancing the science of toxicology. As our mission implies, we endeavor to engage industry professionals, academicians,

and students alike. Continuing the theme of cross-field collaboration and outreach, NESOT is involved annually in a number of opportunities and events. In addition, student outreach efforts include presentations by industry professionals to regional school undergraduate programs and the NESOT Student Travel Awards. The NESOT is proud to share in the

50th Anniversary celebration of the SOT.

Northeast Regional Chapter (NESOT)NESOT Mission: To serve as the focal point for toxicological interests in the

Northeast, to encourage interactions among toxicologists in government, industry, and academia, to sponsor scientific and educational programs in toxicology, and to support the

development of students in the field of toxicology by providing opportunities to present their work and through travel award to the SOT Annual Meeting.

Geographic Area: The Northeast Chapter includes Connecticut, Rhode Island, Massachusetts, New Hampshire, Vermont, Maine, Northeastern New York, and Quebec.

Members of NESOT were at the Center of an International Effort to Identify Next Generation Biomarkers to Screen Kidney Toxicity. The effort was led by Predictive Safety Testing Consortium

(PSTC) which is a collaborative effort of scientists from 15 pharmaceutical companies and 2 biotech companies, four academic institutions, the Critical Path Institute, the Food and Drug Administration

(FDA) and the European Medicines Agency (EMEA; now EMA). These studies provide data supporting the utility of seven renal biomarkers in safety testing in the preclinical setting. They have

now been formally accepted by the US and European regulatory authorities and Japanese Pharmaceuticals and Medical Devices Agency. The original results of these studies were published as

a focus issue by the journal Nature Biotechnology (vol 28, issue 5, May 2010).

Laura Andrews President

Paul Nugent Vice- President

Nicole W. HurstSecretary/Treasurer

Vishal S. VaidyaCouncilor

Felicity Grzemski Councilor

Courtney Kozul HorvathPost-Doc Rep.

Become an NESOT Member!! Student membership in NESOT is a great way to learn about regional research in the field of toxicology in academia, government andindustry.Student benefits include:•Reduced registration fees for the annual meeting and spring event•Competitive student poster award for students presenting at the annual fall meeting •Competitive student travel award to defray SOT Annual Meeting costs given to students submitting their SOT abstracts for review.•The Chapter newsletter (2x a year) with information about NESOT activities, the SOT Annual Meeting, a schedule of upcoming events of interest to toxicologists (eg. symposia and workshops), and more.•NESOT members have an opportunity to participate in Regional Chapter committees.•Membership to NESOT is $15 in addition to the SOT membership, students may join one RC/SS/SIG for free. •Applications can be obtained at our website:

http://www.toxicology.org/isot/rc/nesot/

Founded 1986~215 members 27 academic institutions represented

Highest Membership Among Academic

Institutions: Number Precent

UConn: 12 12 6%

Brown: 7 7 3%

University of Southern Maine: 3 3 1%

Boston University: 3 3 1%

Dartmouth: 3 3 1%

Largest Employers: Number Percent

Pfizer 58 27%

Boerhinger Ingelheim 10 7%

Gradient Corporation 8 4%

Paul Newberg 1986

Mr Paul M Newberne, DVM, DPhil 1987

Mr Paul M Newberne, DVM, DPhil 1988

Robert A Schatz, PhD 1989

Dr John B Morris, PhD 1990

Stanley W. Stadnicki Jr., PhD 1991

Dr Barbara D Beck, PhD, ATS, DABT, ERT 1992

Andrea K Hubbard, PhD 1993

Edward A Khairallah, PhD 1994

Dr Mitchell W Sauerhoff, PhD, DABT 1995

Dr Betty Ann Pettersen, PhD, DABT 1996

William Paul Beierschmitt, PhD, DABT 1997

Dr Kim Boekelheide, MD, PhD 1998

Dr Susan G Emeigh Hart, VMD, PhD, DACVP, DABT, ERT 1999

Dr Michael A Lynes, PhD 2000

John Wise, PhD 2001

Andrea K Hubbard, PhD 2002

Charlie Giardina, PhD 2003

Dr Jatinder Singh, PhD 2004

Dr Helen V Ratajczak Edmond, PhD 2005

Dr Joseph V Rutkowski, PhD, DABT 2006

Mr Douglas J Ball, MS, DABT 2007

Dr Jessica E Sutherland, PhD, DABT 2008

Dr Graeme B J Smith, PhD, DABT 2009

Dr Laura Andrews, PhD, DABT 2010

Past Presidents

Courtney McGinnisStudent Rep.

Graeme SmithPast President

NESOT STATS

Highest degree earned Employment

Membership Type

DABT certified

NESOT Executive Board

Student Awards2010 Student Travel Awards

Meeghan O’Connor (University of Connecticut)-$1000Nick Heger (Brown University)-$750Dan Ferreira (University of Connecticut)-$500

2011 Student Travel AwardsJessica LaRocca (Brown University)-$1000 Priscilla Encarnacao (University of Connecticut)-$750Vijay More (University of Rhode Island)-$500

2010 NESOT Presentation Award

Nick Heger (Brown University)-$1000

2010 NESOT Poster Awards

Edwin Mutanguha (Salve Regina University)-$750

Vijay More (University of Rhode Island)-$500

Krishna Kadaveru (University of Connecticut)-$250

24.65%0.47%

63.26%

3.26%9.30%

AssociateEmeritus FullFullPost-DocStudent

28.84%

71.16% DABT

not certified

11.16%

11.63%

76.28%

1.86%

Bachelor's

Masters

PhD

Other (MD/DVM)

64.7%

1.9%

4.2%

25.1%

4.2%

Pharma/Biotech

Government

Consulting

Academia

Other

Abuse Liability, Pfizer Inc, Groton, CT

Biologics: Past, Present, and

Future Charles River Labortories,

Shrewsbury, MA

The Evolution of Toxicology

Genzyme Inc, Cambridge, MAKeynote: Dr. Ken

Miller

2020: The Next Decade in Toxicology

University of Connecticut,

Storrs, CTKeynote: Dr. Jon

Cook