pregnancy outcomes: all cancers 1 pregnancies in …...pregnancy outcomes: all cancers pregnancies...

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Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 1 CCSS data from Dec2010 and March 2015 data freeze Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including mult iple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant Pregnancy Outcome 2 Any pregnancy 1 Live Births Stillbirths Miscarriages Abortions Unknown 3 All cases N % Total # pregnancies N % N % N % N % N % Both sexes All cases 24362 5601 23.0 11561 7651 66.2 121 1.0 1819 15.7 1467 12.7 503 4.4 Age at baseline <18 5645 39 0.7 44 16 36.4 1 2.3 1 2.3 8 18.2 18 40.9 18-19 2102 114 5.4 151 67 44.4 3 2.0 38 25.2 31 20.5 12 7.9 20-24 5722 904 15.8 1443 831 57.6 12 0.8 249 17.3 247 17.1 104 7.2 25-29 5186 1628 31.4 3058 1943 63.5 31 1.0 479 15.7 413 13.5 192 6.3 30-34 3558 1638 46.0 3661 2555 69.8 31 0.8 524 14.3 430 11.7 121 3.3 35+ 2149 1278 59.5 3204 2239 69.9 43 1.3 528 16.5 338 10.5 56 1.7 Years since diagnosis 5-9 2581 153 5.9 251 134 53.4 1 0.4 30 12.0 36 14.3 50 19.9 10-14 8323 1202 14.4 2211 1410 63.8 25 1.1 313 14.2 348 15.7 115 5.2 15-19 7727 2037 26.4 4122 2772 67.2 42 1.0 612 14.8 511 12.4 185 4.5 20+ 5731 2209 38.5 4977 3335 67.0 53 1.1 864 17.4 572 11.5 153 3.1 Age at diagnosis <1 1842 119 6.5 207 116 56.0 1 0.5 38 18.4 36 17.4 16 7.7 1-4 7771 711 9.1 1183 678 57.3 13 1.1 218 18.4 190 16.1 84 7.1 5-9 5487 998 18.2 1903 1167 61.3 16 0.8 368 19.3 248 13.0 104 5.5 10-14 5181 1834 35.4 3966 2710 68.3 49 1.2 568 14.3 495 12.5 144 3.6 15-20 4081 1939 47.5 4302 2980 69.3 42 1.0 627 14.6 498 11.6 155 3.6 Treatment Surgery only 2068 526 25.4 1066 706 66.2 14 1.3 177 16.6 136 12.8 33 3.1 Chemotherapy, no radiation 7360 1757 23.9 3659 2412 65.9 25 0.7 584 16.0 455 12.4 183 5.0 Radiation, no chemotherapy 2017 615 30.5 1307 870 66.6 21 1.6 203 15.5 172 13.2 41 3.1 Chemotherapy and radiation 10680 2132 20.0 4336 2854 65.8 52 1.2 676 15.6 568 13.1 186 4.3 Unknown 2237 571 25.5 1193 809 67.8 9 0.8 179 15.0 136 11.4 60 5.0 Males All cases 13028 2192 16.8 4254 2957 69.5 37 0.9 615 14.5 440 10.3 205 4.8 Age at baseline <18 3041 7 0.2 7 3 42.9 0 0.0 0 0.0 1 14.3 3 42.9 18-19 1098 38 3.5 45 16 35.6 1 2.2 15 33.3 12 26.7 1 2.2 20-24 3013 275 9.1 403 221 54.8 4 1.0 77 19.1 65 16.1 36 8.9 25-29 2898 645 22.3 1121 739 65.9 9 0.8 166 14.8 131 11.7 76 6.8 30-34 1884 679 36.0 1358 1015 74.7 8 0.6 155 11.4 125 9.2 55 4.1 35+ 1094 548 50.1 1320 963 73.0 15 1.1 202 15.3 106 8.0 34 2.6 Years since diagnosis 5-9 1449 50 3.5 83 39 47.0 0 0.0 9 10.8 8 9.6 27 32.5 10-14 4458 435 9.8 730 495 67.8 5 0.7 107 14.7 85 11.6 38 5.2 15-19 4062 795 19.6 1490 1062 71.3 13 0.9 199 13.4 146 9.8 70 4.7 20+ 3059 912 29.8 1951 1361 69.8 19 1.0 300 15.4 201 10.3 70 3.6 Age at diagnosis <1 944 35 3.7 56 28 50.0 1 1.8 10 17.9 13 23.2 4 7.1 1-4 4070 255 6.3 409 234 57.2 6 1.5 75 18.3 63 15.4 31 7.6 5-9 3099 383 12.4 658 421 64.0 6 0.9 109 16.6 85 12.9 37 5.6 10-14 2742 677 24.7 1354 982 72.5 9 0.7 188 13.9 122 9.0 53 3.9 15-20 2173 842 38.7 1777 1292 72.7 15 0.8 233 13.1 157 8.8 80 4.5 Treatment Surgery only 1028 200 19.5 381 272 71.4 3 0.8 49 12.9 49 12.9 8 2.1 Chemotherapy, no radiation 3870 723 18.7 1447 990 68.4 9 0.6 229 15.8 142 9.8 77 5.3 Radiation, no chemotherapy 1046 253 24.2 516 368 71.3 6 1.2 71 13.8 53 10.3 18 3.5 Chemotherapy and radiation 5764 756 13.1 1425 996 69.9 14 1.0 198 13.9 144 10.1 73 5.1 Unknown 1320 260 19.7 485 331 68.2 5 1.0 68 14.0 52 10.7 29 6.0 Females All cases 11334 3409 30.1 7307 4694 64.2 84 1.1 1204 16.5 1027 14.1 298 4.1 Age at baseline <18 2604 32 1.2 37 13 35.1 1 2.7 1 2.7 7 18.9 15 40.5

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Page 1: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

Pregnancy Outcomes: All cancers

Pregnancies in female survivors or female partners of male survivors

1

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 24362 5601 23.0 11561 7651 66.2 121 1.0 1819 15.7 1467 12.7 503 4.4

Age at baseline <18 5645 39 0.7 44 16 36.4 1 2.3 1 2.3 8 18.2 18 40.9

18-19 2102 114 5.4 151 67 44.4 3 2.0 38 25.2 31 20.5 12 7.9

20-24 5722 904 15.8 1443 831 57.6 12 0.8 249 17.3 247 17.1 104 7.2

25-29 5186 1628 31.4 3058 1943 63.5 31 1.0 479 15.7 413 13.5 192 6.3

30-34 3558 1638 46.0 3661 2555 69.8 31 0.8 524 14.3 430 11.7 121 3.3

35+ 2149 1278 59.5 3204 2239 69.9 43 1.3 528 16.5 338 10.5 56 1.7

Years since diagnosis 5-9 2581 153 5.9 251 134 53.4 1 0.4 30 12.0 36 14.3 50 19.9

10-14 8323 1202 14.4 2211 1410 63.8 25 1.1 313 14.2 348 15.7 115 5.2

15-19 7727 2037 26.4 4122 2772 67.2 42 1.0 612 14.8 511 12.4 185 4.5

20+ 5731 2209 38.5 4977 3335 67.0 53 1.1 864 17.4 572 11.5 153 3.1

Age at diagnosis <1 1842 119 6.5 207 116 56.0 1 0.5 38 18.4 36 17.4 16 7.7

1-4 7771 711 9.1 1183 678 57.3 13 1.1 218 18.4 190 16.1 84 7.1

5-9 5487 998 18.2 1903 1167 61.3 16 0.8 368 19.3 248 13.0 104 5.5

10-14 5181 1834 35.4 3966 2710 68.3 49 1.2 568 14.3 495 12.5 144 3.6

15-20 4081 1939 47.5 4302 2980 69.3 42 1.0 627 14.6 498 11.6 155 3.6

Treatment Surgery only 2068 526 25.4 1066 706 66.2 14 1.3 177 16.6 136 12.8 33 3.1

Chemotherapy, no radiation 7360 1757 23.9 3659 2412 65.9 25 0.7 584 16.0 455 12.4 183 5.0

Radiation, no chemotherapy 2017 615 30.5 1307 870 66.6 21 1.6 203 15.5 172 13.2 41 3.1

Chemotherapy and radiation 10680 2132 20.0 4336 2854 65.8 52 1.2 676 15.6 568 13.1 186 4.3

Unknown 2237 571 25.5 1193 809 67.8 9 0.8 179 15.0 136 11.4 60 5.0

Males All cases 13028 2192 16.8 4254 2957 69.5 37 0.9 615 14.5 440 10.3 205 4.8

Age at baseline <18 3041 7 0.2 7 3 42.9 0 0.0 0 0.0 1 14.3 3 42.9

18-19 1098 38 3.5 45 16 35.6 1 2.2 15 33.3 12 26.7 1 2.2

20-24 3013 275 9.1 403 221 54.8 4 1.0 77 19.1 65 16.1 36 8.9

25-29 2898 645 22.3 1121 739 65.9 9 0.8 166 14.8 131 11.7 76 6.8

30-34 1884 679 36.0 1358 1015 74.7 8 0.6 155 11.4 125 9.2 55 4.1

35+ 1094 548 50.1 1320 963 73.0 15 1.1 202 15.3 106 8.0 34 2.6

Years since diagnosis 5-9 1449 50 3.5 83 39 47.0 0 0.0 9 10.8 8 9.6 27 32.5

10-14 4458 435 9.8 730 495 67.8 5 0.7 107 14.7 85 11.6 38 5.2

15-19 4062 795 19.6 1490 1062 71.3 13 0.9 199 13.4 146 9.8 70 4.7

20+ 3059 912 29.8 1951 1361 69.8 19 1.0 300 15.4 201 10.3 70 3.6

Age at diagnosis <1 944 35 3.7 56 28 50.0 1 1.8 10 17.9 13 23.2 4 7.1

1-4 4070 255 6.3 409 234 57.2 6 1.5 75 18.3 63 15.4 31 7.6

5-9 3099 383 12.4 658 421 64.0 6 0.9 109 16.6 85 12.9 37 5.6

10-14 2742 677 24.7 1354 982 72.5 9 0.7 188 13.9 122 9.0 53 3.9

15-20 2173 842 38.7 1777 1292 72.7 15 0.8 233 13.1 157 8.8 80 4.5

Treatment Surgery only 1028 200 19.5 381 272 71.4 3 0.8 49 12.9 49 12.9 8 2.1

Chemotherapy, no radiation 3870 723 18.7 1447 990 68.4 9 0.6 229 15.8 142 9.8 77 5.3

Radiation, no chemotherapy 1046 253 24.2 516 368 71.3 6 1.2 71 13.8 53 10.3 18 3.5

Chemotherapy and radiation 5764 756 13.1 1425 996 69.9 14 1.0 198 13.9 144 10.1 73 5.1

Unknown 1320 260 19.7 485 331 68.2 5 1.0 68 14.0 52 10.7 29 6.0

Females All cases 11334 3409 30.1 7307 4694 64.2 84 1.1 1204 16.5 1027 14.1 298 4.1

Age at baseline <18 2604 32 1.2 37 13 35.1 1 2.7 1 2.7 7 18.9 15 40.5

Page 2: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

Pregnancy Outcomes: All cancers

Pregnancies in female survivors or female partners of male survivors

2

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 1004 76 7.6 106 51 48.1 2 1.9 23 21.7 19 17.9 11 10.4

20-24 2709 629 23.2 1040 610 58.7 8 0.8 172 16.5 182 17.5 68 6.5

25-29 2288 983 43.0 1937 1204 62.2 22 1.1 313 16.2 282 14.6 116 6.0

30-34 1674 959 57.3 2303 1540 66.9 23 1.0 369 16.0 305 13.2 66 2.9

35+ 1055 730 69.2 1884 1276 67.7 28 1.5 326 17.3 232 12.3 22 1.2

Years since diagnosis 5-9 1132 103 9.1 168 95 56.5 1 0.6 21 12.5 28 16.7 23 13.7

10-14 3865 767 19.8 1481 915 61.8 20 1.4 206 13.9 263 17.8 77 5.2

15-19 3665 1242 33.9 2632 1710 65.0 29 1.1 413 15.7 365 13.9 115 4.4

20+ 2672 1297 48.5 3026 1974 65.2 34 1.1 564 18.6 371 12.3 83 2.7

Age at diagnosis <1 898 84 9.4 151 88 58.3 0 0.0 28 18.5 23 15.2 12 7.9

1-4 3701 456 12.3 774 444 57.4 7 0.9 143 18.5 127 16.4 53 6.8

5-9 2388 615 25.8 1245 746 59.9 10 0.8 259 20.8 163 13.1 67 5.4

10-14 2439 1157 47.4 2612 1728 66.2 40 1.5 380 14.5 373 14.3 91 3.5

15-20 1908 1097 57.5 2525 1688 66.9 27 1.1 394 15.6 341 13.5 75 3.0

Treatment Surgery only 1040 326 31.3 685 434 63.4 11 1.6 128 18.7 87 12.7 25 3.6

Chemotherapy, no radiation 3490 1034 29.6 2212 1422 64.3 16 0.7 355 16.0 313 14.2 106 4.8

Radiation, no chemotherapy 971 362 37.3 791 502 63.5 15 1.9 132 16.7 119 15.0 23 2.9

Chemotherapy and radiation 4916 1376 28.0 2911 1858 63.8 38 1.3 478 16.4 424 14.6 113 3.9

Unknown 917 311 33.9 708 478 67.5 4 0.6 111 15.7 84 11.9 31 4.4

Page 3: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: All leukemias

Pregnancies in female survivors or female partners of male survivors

3

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 7319 1394 19.0 2741 1832 66.8 31 1.1 421 15.4 326 11.9 131 4.8

Age at baseline <18 2222 13 0.6 13 5 38.5 1 7.7 0 0.0 2 15.4 5 38.5

18-19 819 40 4.9 52 21 40.4 2 3.8 15 28.8 8 15.4 6 11.5

20-24 1817 319 17.6 500 305 61.0 5 1.0 75 15.0 84 16.8 31 6.2

25-29 1435 471 32.8 871 565 64.9 4 0.5 138 15.8 118 13.5 46 5.3

30-34 712 357 50.1 816 569 69.7 11 1.3 122 15.0 82 10.0 32 3.9

35+ 314 194 61.8 489 367 75.1 8 1.6 71 14.5 32 6.5 11 2.2

Years since diagnosis 5-9 977 32 3.3 52 30 57.7 0 0.0 3 5.8 9 17.3 10 19.2

10-14 2626 268 10.2 456 290 63.6 5 1.1 64 14.0 71 15.6 26 5.7

15-19 2232 526 23.6 988 664 67.2 12 1.2 137 13.9 127 12.9 48 4.9

20+ 1484 568 38.3 1245 848 68.1 14 1.1 217 17.4 119 9.6 47 3.8

Age at diagnosis <1 226 12 5.3 19 9 47.4 0 0.0 4 21.1 4 21.1 2 10.5

1-4 3429 296 8.6 477 282 59.1 6 1.3 83 17.4 71 14.9 35 7.3

5-9 1806 358 19.8 692 432 62.4 7 1.0 138 19.9 84 12.1 31 4.5

10-14 1216 449 36.9 950 663 69.8 13 1.4 125 13.2 109 11.5 40 4.2

15-20 642 279 43.5 603 446 74.0 5 0.8 71 11.8 58 9.6 23 3.8

Treatment Surgery only 2 . . . . . . . . . . . . .

Chemotherapy, no radiation 2929 605 20.7 1213 810 66.8 10 0.8 193 15.9 135 11.1 65 5.4

Radiation, no chemotherapy 4 2 50.0 6 4 66.7 0 0.0 2 33.3 0 0.0 0 0.0

Chemotherapy and radiation 3740 645 17.2 1257 829 66.0 20 1.6 192 15.3 159 12.6 57 4.5

Unknown 644 142 22.0 265 189 71.3 1 0.4 34 12.8 32 12.1 9 3.4

Males All cases 3906 566 14.5 1066 759 71.2 11 1.0 150 14.1 92 8.6 54 5.1

Age at baseline <18 1214 1 0.1 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

18-19 439 12 2.7 14 4 28.6 1 7.1 8 57.1 1 7.1 0 0.0

20-24 921 97 10.5 138 79 57.2 4 2.9 25 18.1 20 14.5 10 7.2

25-29 783 197 25.2 345 230 66.7 0 0.0 49 14.2 40 11.6 26 7.5

30-34 372 159 42.7 327 257 78.6 4 1.2 39 11.9 17 5.2 10 3.1

35+ 177 100 56.5 241 188 78.0 2 0.8 29 12.0 14 5.8 8 3.3

Years since diagnosis 5-9 556 11 2.0 18 7 38.9 0 0.0 1 5.6 2 11.1 8 44.4

10-14 1407 104 7.4 161 113 70.2 3 1.9 24 14.9 16 9.9 5 3.1

15-19 1153 226 19.6 428 305 71.3 6 1.4 56 13.1 44 10.3 17 4.0

20+ 790 225 28.5 459 334 72.8 2 0.4 69 15.0 30 6.5 24 5.2

Age at diagnosis <1 105 1 1.0 3 1 33.3 0 0.0 1 33.3 0 0.0 1 33.3

1-4 1835 109 5.9 169 98 58.0 4 2.4 32 18.9 20 11.8 15 8.9

5-9 973 118 12.1 200 136 68.0 1 0.5 37 18.5 18 9.0 8 4.0

10-14 601 164 27.3 330 244 73.9 3 0.9 43 13.0 24 7.3 16 4.8

15-20 392 174 44.4 364 280 76.9 3 0.8 37 10.2 30 8.2 14 3.8

Treatment Surgery only 1 . . . . . . . . . . . . .

Chemotherapy, no radiation 1459 241 16.5 474 331 69.8 3 0.6 76 16.0 34 7.2 30 6.3

Radiation, no chemotherapy 3 1 33.3 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy and radiation 2055 261 12.7 480 343 71.5 7 1.5 63 13.1 48 10.0 19 4.0

Unknown 388 63 16.2 109 82 75.2 1 0.9 11 10.1 10 9.2 5 4.6

Females All cases 3413 828 24.3 1675 1073 64.1 20 1.2 271 16.2 234 14.0 77 4.6

Age at baseline <18 1008 12 1.2 12 4 33.3 1 8.3 0 0.0 2 16.7 5 41.7

Page 4: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: All leukemias

Pregnancies in female survivors or female partners of male survivors

4

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 380 28 7.4 38 17 44.7 1 2.6 7 18.4 7 18.4 6 15.8

20-24 896 222 24.8 362 226 62.4 1 0.3 50 13.8 64 17.7 21 5.8

25-29 652 274 42.0 526 335 63.7 4 0.8 89 16.9 78 14.8 20 3.8

30-34 340 198 58.2 489 312 63.8 7 1.4 83 17.0 65 13.3 22 4.5

35+ 137 94 68.6 248 179 72.2 6 2.4 42 16.9 18 7.3 3 1.2

Years since diagnosis 5-9 421 21 5.0 34 23 67.6 0 0.0 2 5.9 7 20.6 2 5.9

10-14 1219 164 13.5 295 177 60.0 2 0.7 40 13.6 55 18.6 21 7.1

15-19 1079 300 27.8 560 359 64.1 6 1.1 81 14.5 83 14.8 31 5.5

20+ 694 343 49.4 786 514 65.4 12 1.5 148 18.8 89 11.3 23 2.9

Age at diagnosis <1 121 11 9.1 16 8 50.0 0 0.0 3 18.8 4 25.0 1 6.3

1-4 1594 187 11.7 308 184 59.7 2 0.6 51 16.6 51 16.6 20 6.5

5-9 833 240 28.8 492 296 60.2 6 1.2 101 20.5 66 13.4 23 4.7

10-14 615 285 46.3 620 419 67.6 10 1.6 82 13.2 85 13.7 24 3.9

15-20 250 105 42.0 239 166 69.5 2 0.8 34 14.2 28 11.7 9 3.8

Treatment Surgery only 1 . . . . . . . . . . . . .

Chemotherapy, no radiation 1470 364 24.8 739 479 64.8 7 0.9 117 15.8 101 13.7 35 4.7

Radiation, no chemotherapy 1 1 100.0 3 1 33.3 0 0.0 2 66.7 0 0.0 0 0.0

Chemotherapy and radiation 1685 384 22.8 777 486 62.5 13 1.7 129 16.6 111 14.3 38 4.9

Unknown 256 79 30.9 156 107 68.6 0 0.0 23 14.7 22 14.1 4 2.6

Page 5: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: ALL 5

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 6148 1174 19.1 2284 1539 67.4 28 1.2 342 15.0 262 11.5 113 4.9

Age at baseline <18 1932 10 0.5 10 5 50.0 0 0.0 0 0.0 0 0.0 5 50.0

18-19 706 37 5.2 49 20 40.8 2 4.1 14 28.6 7 14.3 6 12.2

20-24 1555 294 18.9 465 290 62.4 5 1.1 66 14.2 74 15.9 30 6.5

25-29 1188 408 34.3 764 505 66.1 4 0.5 119 15.6 95 12.4 41 5.4

30-34 545 274 50.3 614 426 69.4 10 1.6 95 15.5 61 9.9 22 3.6

35+ 222 151 68.0 382 293 76.7 7 1.8 48 12.6 25 6.5 9 2.4

Years since diagnosis 5-9 842 26 3.1 44 26 59.1 0 0.0 3 6.8 8 18.2 7 15.9

10-14 2214 220 9.9 369 235 63.7 4 1.1 51 13.8 56 15.2 23 6.2

15-19 1851 443 23.9 824 556 67.5 11 1.3 113 13.7 104 12.6 40 4.9

20+ 1241 485 39.1 1047 722 69.0 13 1.2 175 16.7 94 9.0 43 4.1

Age at diagnosis <1 121 7 5.8 14 6 42.9 0 0.0 4 28.6 2 14.3 2 14.3

1-4 3043 272 8.9 445 272 61.1 5 1.1 73 16.4 61 13.7 34 7.6

5-9 1588 320 20.2 600 377 62.8 7 1.2 116 19.3 71 11.8 29 4.8

10-14 956 371 38.8 782 554 70.8 11 1.4 104 13.3 81 10.4 32 4.1

15-20 440 204 46.4 443 330 74.5 5 1.1 45 10.2 47 10.6 16 3.6

Treatment Chemotherapy, no radiation 2300 469 20.4 921 620 67.3 8 0.9 145 15.7 96 10.4 52 5.6

Radiation, no chemotherapy 3 2 66.7 6 4 66.7 0 0.0 2 33.3 0 0.0 0 0.0

Chemotherapy and radiation 3283 580 17.7 1133 754 66.5 19 1.7 168 14.8 136 12.0 56 4.9

Unknown 562 123 21.9 224 161 71.9 1 0.4 27 12.1 30 13.4 5 2.2

Males All cases 3308 475 14.4 892 626 70.2 10 1.1 126 14.1 83 9.3 47 5.3

Age at baseline <18 1057 1 0.1 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

18-19 382 10 2.6 12 4 33.3 1 8.3 7 58.3 0 0.0 0 0.0

20-24 789 92 11.7 133 76 57.1 4 3.0 24 18.0 19 14.3 10 7.5

25-29 660 173 26.2 306 207 67.6 0 0.0 40 13.1 36 11.8 23 7.5

30-34 290 119 41.0 242 184 76.0 3 1.2 32 13.2 15 6.2 8 3.3

35+ 130 80 61.5 198 154 77.8 2 1.0 23 11.6 13 6.6 6 3.0

Years since diagnosis 5-9 480 9 1.9 15 6 40.0 0 0.0 1 6.7 2 13.3 6 40.0

10-14 1195 84 7.0 127 87 68.5 3 2.4 17 13.4 15 11.8 5 3.9

15-19 969 185 19.1 352 246 69.9 5 1.4 48 13.6 39 11.1 14 4.0

20+ 664 197 29.7 398 287 72.1 2 0.5 60 15.1 27 6.8 22 5.5

Age at diagnosis <1 59 1 1.7 3 1 33.3 0 0.0 1 33.3 0 0.0 1 33.3

1-4 1623 99 6.1 158 94 59.5 4 2.5 30 19.0 16 10.1 14 8.9

5-9 864 110 12.7 184 123 66.8 1 0.5 34 18.5 18 9.8 8 4.3

10-14 487 137 28.1 277 203 73.3 2 0.7 36 13.0 22 7.9 14 5.1

15-20 275 128 46.5 270 205 75.9 3 1.1 25 9.3 27 10.0 10 3.7

Treatment Chemotherapy, no radiation 1142 182 15.9 360 247 68.6 2 0.6 59 16.4 28 7.8 24 6.7

Radiation, no chemotherapy 2 1 50.0 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy and radiation 1823 239 13.1 437 305 69.8 7 1.6 60 13.7 46 10.5 19 4.3

Unknown 341 53 15.5 92 71 77.2 1 1.1 7 7.6 9 9.8 4 4.3

Females All cases 2840 699 24.6 1392 913 65.6 18 1.3 216 15.5 179 12.9 66 4.7

Age at baseline <18 875 9 1.0 9 4 44.4 0 0.0 0 0.0 0 0.0 5 55.6

18-19 324 27 8.3 37 16 43.2 1 2.7 7 18.9 7 18.9 6 16.2

20-24 766 202 26.4 332 214 64.5 1 0.3 42 12.7 55 16.6 20 6.0

Page 6: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: ALL 6

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

25-29 528 235 44.5 458 298 65.1 4 0.9 79 17.2 59 12.9 18 3.9

30-34 255 155 60.8 372 242 65.1 7 1.9 63 16.9 46 12.4 14 3.8

35+ 92 71 77.2 184 139 75.5 5 2.7 25 13.6 12 6.5 3 1.6

Years since diagnosis 5-9 362 17 4.7 29 20 69.0 0 0.0 2 6.9 6 20.7 1 3.4

10-14 1019 136 13.3 242 148 61.2 1 0.4 34 14.0 41 16.9 18 7.4

15-19 882 258 29.3 472 310 65.7 6 1.3 65 13.8 65 13.8 26 5.5

20+ 577 288 49.9 649 435 67.0 11 1.7 115 17.7 67 10.3 21 3.2

Age at diagnosis <1 62 6 9.7 11 5 45.5 0 0.0 3 27.3 2 18.2 1 9.1

1-4 1420 173 12.2 287 178 62.0 1 0.3 43 15.0 45 15.7 20 7.0

5-9 724 210 29.0 416 254 61.1 6 1.4 82 19.7 53 12.7 21 5.0

10-14 469 234 49.9 505 351 69.5 9 1.8 68 13.5 59 11.7 18 3.6

15-20 165 76 46.1 173 125 72.3 2 1.2 20 11.6 20 11.6 6 3.5

Treatment Chemotherapy, no radiation 1158 287 24.8 561 373 66.5 6 1.1 86 15.3 68 12.1 28 5.0

Radiation, no chemotherapy 1 1 100.0 3 1 33.3 0 0.0 2 66.7 0 0.0 0 0.0

Chemotherapy and radiation 1460 341 23.4 696 449 64.5 12 1.7 108 15.5 90 12.9 37 5.3

Unknown 221 70 31.7 132 90 68.2 0 0.0 20 15.2 21 15.9 1 0.8

Page 7: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: AML 7

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 868 166 19.1 352 225 63.9 2 0.6 60 17.0 54 15.3 11 3.1

Age at baseline <18 227 3 1.3 3 0 0.0 1 33.3 0 0.0 2 66.7 0 0.0

18-19 89 2 2.2 2 1 50.0 0 0.0 0 0.0 1 50.0 0 0.0

20-24 187 21 11.2 29 12 41.4 0 0.0 7 24.1 9 31.0 1 3.4

25-29 181 45 24.9 77 43 55.8 0 0.0 17 22.1 16 20.8 1 1.3

30-34 123 67 54.5 171 121 70.8 1 0.6 23 13.5 19 11.1 7 4.1

35+ 61 28 45.9 70 48 68.6 0 0.0 13 18.6 7 10.0 2 2.9

Years since diagnosis 5-9 84 4 4.8 4 2 50.0 0 0.0 0 0.0 1 25.0 1 25.0

10-14 318 34 10.7 62 39 62.9 1 1.6 11 17.7 10 16.1 1 1.6

15-19 297 69 23.2 140 93 66.4 1 0.7 16 11.4 23 16.4 7 5.0

20+ 169 59 34.9 146 91 62.3 0 0.0 33 22.6 20 13.7 2 1.4

Age at diagnosis <1 90 5 5.6 5 3 60.0 0 0.0 0 0.0 2 40.0 0 0.0

1-4 294 16 5.4 21 6 28.6 1 4.8 8 38.1 6 28.6 0 0.0

5-9 160 32 20.0 81 49 60.5 0 0.0 19 23.5 12 14.8 1 1.2

10-14 183 61 33.3 129 81 62.8 1 0.8 13 10.1 27 20.9 7 5.4

15-20 141 52 36.9 116 86 74.1 0 0.0 20 17.2 7 6.0 3 2.6

Treatment Surgery only 2 . . . . . . . . . . . . .

Chemotherapy, no radiation 525 113 21.5 246 159 64.6 2 0.8 42 17.1 35 14.2 8 3.3

Radiation, no chemotherapy 1 . . . . . . . . . . . . .

Chemotherapy and radiation 285 39 13.7 76 46 60.5 0 0.0 12 15.8 17 22.4 1 1.3

Unknown 55 14 25.5 30 20 66.7 0 0.0 6 20.0 2 6.7 2 6.7

Males All cases 429 63 14.7 126 95 75.4 1 0.8 19 15.1 7 5.6 4 3.2

Age at baseline <18 123 . . . . . . . . . . . . .

18-19 45 1 2.2 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

20-24 90 4 4.4 4 2 50.0 0 0.0 1 25.0 1 25.0 0 0.0

25-29 81 15 18.5 24 15 62.5 0 0.0 7 29.2 2 8.3 0 0.0

30-34 60 32 53.3 70 58 82.9 1 1.4 7 10.0 2 2.9 2 2.9

35+ 30 11 36.7 27 20 74.1 0 0.0 4 14.8 1 3.7 2 7.4

Years since diagnosis 5-9 50 1 2.0 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

10-14 158 12 7.6 20 15 75.0 0 0.0 5 25.0 0 0.0 0 0.0

15-19 138 32 23.2 63 48 76.2 1 1.6 6 9.5 5 7.9 3 4.8

20+ 83 18 21.7 42 31 73.8 0 0.0 8 19.0 2 4.8 1 2.4

Age at diagnosis <1 38 . . . . . . . . . . . . .

1-4 160 7 4.4 7 3 42.9 0 0.0 1 14.3 3 42.9 0 0.0

5-9 74 6 8.1 14 11 78.6 0 0.0 3 21.4 0 0.0 0 0.0

10-14 77 20 26.0 41 31 75.6 1 2.4 5 12.2 2 4.9 2 4.9

15-20 80 30 37.5 64 50 78.1 0 0.0 10 15.6 2 3.1 2 3.1

Treatment Surgery only 1 . . . . . . . . . . . . .

Chemotherapy, no radiation 253 46 18.2 92 69 75.0 1 1.1 14 15.2 5 5.4 3 3.3

Radiation, no chemotherapy 1 . . . . . . . . . . . . .

Chemotherapy and radiation 143 10 7.0 21 18 85.7 0 0.0 2 9.5 1 4.8 0 0.0

Unknown 31 7 22.6 13 8 61.5 0 0.0 3 23.1 1 7.7 1 7.7

Females All cases 439 103 23.5 226 130 57.5 1 0.4 41 18.1 47 20.8 7 3.1

Age at baseline <18 104 3 2.9 3 0 0.0 1 33.3 0 0.0 2 66.7 0 0.0

Page 8: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: AML 8

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 44 1 2.3 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

20-24 97 17 17.5 25 10 40.0 0 0.0 6 24.0 8 32.0 1 4.0

25-29 100 30 30.0 53 28 52.8 0 0.0 10 18.9 14 26.4 1 1.9

30-34 63 35 55.6 101 63 62.4 0 0.0 16 15.8 17 16.8 5 5.0

35+ 31 17 54.8 43 28 65.1 0 0.0 9 20.9 6 14.0 0 0.0

Years since diagnosis 5-9 34 3 8.8 3 1 33.3 0 0.0 0 0.0 1 33.3 1 33.3

10-14 160 22 13.8 42 24 57.1 1 2.4 6 14.3 10 23.8 1 2.4

15-19 159 37 23.3 77 45 58.4 0 0.0 10 13.0 18 23.4 4 5.2

20+ 86 41 47.7 104 60 57.7 0 0.0 25 24.0 18 17.3 1 1.0

Age at diagnosis <1 52 5 9.6 5 3 60.0 0 0.0 0 0.0 2 40.0 0 0.0

1-4 134 9 6.7 14 3 21.4 1 7.1 7 50.0 3 21.4 0 0.0

5-9 86 26 30.2 67 38 56.7 0 0.0 16 23.9 12 17.9 1 1.5

10-14 106 41 38.7 88 50 56.8 0 0.0 8 9.1 25 28.4 5 5.7

15-20 61 22 36.1 52 36 69.2 0 0.0 10 19.2 5 9.6 1 1.9

Treatment Surgery only 1 . . . . . . . . . . . . .

Chemotherapy, no radiation 272 67 24.6 154 90 58.4 1 0.6 28 18.2 30 19.5 5 3.2

Chemotherapy and radiation 142 29 20.4 55 28 50.9 0 0.0 10 18.2 16 29.1 1 1.8

Unknown 24 7 29.2 17 12 70.6 0 0.0 3 17.6 1 5.9 1 5.9

Page 9: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: All CNS

Pregnancies in female survivors or female partners of male survivors

9

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 4325 661 15.3 1225 793 64.7 15 1.2 206 16.8 163 13.3 48 3.9

Age at baseline <18 948 3 0.3 3 1 33.3 0 0.0 0 0.0 2 66.7 0 0.0

18-19 371 8 2.2 8 3 37.5 0 0.0 1 12.5 2 25.0 2 25.0

20-24 1136 102 9.0 156 84 53.8 2 1.3 38 24.4 20 12.8 12 7.7

25-29 1037 216 20.8 378 238 63.0 4 1.1 61 16.1 61 16.1 14 3.7

30-34 584 208 35.6 402 278 69.2 3 0.7 60 14.9 44 10.9 17 4.2

35+ 249 124 49.8 278 189 68.0 6 2.2 46 16.5 34 12.2 3 1.1

Years since diagnosis 5-9 461 18 3.9 33 15 45.5 1 3.0 5 15.2 5 15.2 7 21.2

10-14 1536 138 9.0 223 143 64.1 2 0.9 26 11.7 43 19.3 9 4.0

15-19 1349 240 17.8 446 278 62.3 5 1.1 80 17.9 62 13.9 21 4.7

20+ 979 265 27.1 523 357 68.3 7 1.3 95 18.2 53 10.1 11 2.1

Age at diagnosis <1 209 4 1.9 11 6 54.5 0 0.0 3 27.3 1 9.1 1 9.1

1-4 1275 66 5.2 94 57 60.6 1 1.1 18 19.1 14 14.9 4 4.3

5-9 1349 155 11.5 279 164 58.8 2 0.7 63 22.6 36 12.9 14 5.0

10-14 1031 262 25.4 494 338 68.4 9 1.8 69 14.0 66 13.4 12 2.4

15-20 461 174 37.7 347 228 65.7 3 0.9 53 15.3 46 13.3 17 4.9

Treatment Surgery only 1221 315 25.8 595 395 66.4 9 1.5 98 16.5 79 13.3 14 2.4

Chemotherapy, no radiation 317 32 10.1 77 48 62.3 1 1.3 15 19.5 8 10.4 5 6.5

Radiation, no chemotherapy 1133 185 16.3 333 212 63.7 4 1.2 57 17.1 46 13.8 14 4.2

Chemotherapy and radiation 1262 72 5.7 118 70 59.3 0 0.0 17 14.4 19 16.1 12 10.2

Unknown 392 57 14.5 102 68 66.7 1 1.0 19 18.6 11 10.8 3 2.9

Males All cases 2360 279 11.8 474 333 70.3 3 0.6 61 12.9 53 11.2 24 5.1

Age at baseline <18 527 2 0.4 2 1 50.0 0 0.0 0 0.0 1 50.0 0 0.0

18-19 188 4 2.1 4 2 50.0 0 0.0 0 0.0 2 50.0 0 0.0

20-24 610 29 4.8 42 26 61.9 0 0.0 9 21.4 3 7.1 4 9.5

25-29 595 97 16.3 161 107 66.5 1 0.6 24 14.9 23 14.3 6 3.7

30-34 308 91 29.5 151 110 72.8 1 0.7 14 9.3 14 9.3 12 7.9

35+ 132 56 42.4 114 87 76.3 1 0.9 14 12.3 10 8.8 2 1.8

Years since diagnosis 5-9 262 10 3.8 20 11 55.0 0 0.0 3 15.0 1 5.0 5 25.0

10-14 830 54 6.5 83 55 66.3 0 0.0 10 12.0 14 16.9 4 4.8

15-19 736 98 13.3 152 103 67.8 1 0.7 20 13.2 19 12.5 9 5.9

20+ 532 117 22.0 219 164 74.9 2 0.9 28 12.8 19 8.7 6 2.7

Age at diagnosis <1 120 . . . . . . . . . . . . .

1-4 677 33 4.9 47 30 63.8 1 2.1 8 17.0 7 14.9 1 2.1

5-9 755 59 7.8 95 59 62.1 0 0.0 15 15.8 14 14.7 7 7.4

10-14 553 111 20.1 196 149 76.0 2 1.0 22 11.2 17 8.7 6 3.1

15-20 255 76 29.8 136 95 69.9 0 0.0 16 11.8 15 11.0 10 7.4

Treatment Surgery only 625 132 21.1 225 167 74.2 2 0.9 25 11.1 27 12.0 4 1.8

Chemotherapy, no radiation 169 16 9.5 32 23 71.9 1 3.1 3 9.4 3 9.4 2 6.3

Radiation, no chemotherapy 593 75 12.6 123 88 71.5 0 0.0 15 12.2 12 9.8 8 6.5

Chemotherapy and radiation 755 30 4.0 52 31 59.6 0 0.0 8 15.4 5 9.6 8 15.4

Unknown 218 26 11.9 42 24 57.1 0 0.0 10 23.8 6 14.3 2 4.8

Females All cases 1965 382 19.4 751 460 61.3 12 1.6 145 19.3 110 14.6 24 3.2

Age at baseline <18 421 1 0.2 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

Page 10: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: All CNS

Pregnancies in female survivors or female partners of male survivors

10

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 183 4 2.2 4 1 25.0 0 0.0 1 25.0 0 0.0 2 50.0

20-24 526 73 13.9 114 58 50.9 2 1.8 29 25.4 17 14.9 8 7.0

25-29 442 119 26.9 217 131 60.4 3 1.4 37 17.1 38 17.5 8 3.7

30-34 276 117 42.4 251 168 66.9 2 0.8 46 18.3 30 12.0 5 2.0

35+ 117 68 58.1 164 102 62.2 5 3.0 32 19.5 24 14.6 1 0.6

Years since diagnosis 5-9 199 8 4.0 13 4 30.8 1 7.7 2 15.4 4 30.8 2 15.4

10-14 706 84 11.9 140 88 62.9 2 1.4 16 11.4 29 20.7 5 3.6

15-19 613 142 23.2 294 175 59.5 4 1.4 60 20.4 43 14.6 12 4.1

20+ 447 148 33.1 304 193 63.5 5 1.6 67 22.0 34 11.2 5 1.6

Age at diagnosis <1 89 4 4.5 11 6 54.5 0 0.0 3 27.3 1 9.1 1 9.1

1-4 598 33 5.5 47 27 57.4 0 0.0 10 21.3 7 14.9 3 6.4

5-9 594 96 16.2 184 105 57.1 2 1.1 48 26.1 22 12.0 7 3.8

10-14 478 151 31.6 298 189 63.4 7 2.3 47 15.8 49 16.4 6 2.0

15-20 206 98 47.6 211 133 63.0 3 1.4 37 17.5 31 14.7 7 3.3

Treatment Surgery only 596 183 30.7 370 228 61.6 7 1.9 73 19.7 52 14.1 10 2.7

Chemotherapy, no radiation 148 16 10.8 45 25 55.6 0 0.0 12 26.7 5 11.1 3 6.7

Radiation, no chemotherapy 540 110 20.4 210 124 59.0 4 1.9 42 20.0 34 16.2 6 2.9

Chemotherapy and radiation 507 42 8.3 66 39 59.1 0 0.0 9 13.6 14 21.2 4 6.1

Unknown 174 31 17.8 60 44 73.3 1 1.7 9 15.0 5 8.3 1 1.7

Page 11: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Astrocytomas 11

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 2594 486 18.7 907 595 65.6 11 1.2 157 17.3 110 12.1 34 3.7

Age at baseline <18 527 1 0.2 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

18-19 211 5 2.4 5 3 60.0 0 0.0 1 20.0 1 20.0 0 0.0

20-24 690 80 11.6 124 67 54.0 2 1.6 29 23.4 16 12.9 10 8.1

25-29 634 169 26.7 292 183 62.7 2 0.7 47 16.1 50 17.1 10 3.4

30-34 363 142 39.1 291 202 69.4 2 0.7 50 17.2 26 8.9 11 3.8

35+ 169 89 52.7 194 139 71.6 5 2.6 30 15.5 17 8.8 3 1.5

Years since diagnosis 5-9 237 14 5.9 26 12 46.2 1 3.8 5 19.2 5 19.2 3 11.5

10-14 904 95 10.5 155 103 66.5 0 0.0 17 11.0 30 19.4 5 3.2

15-19 796 174 21.9 328 208 63.4 4 1.2 62 18.9 38 11.6 16 4.9

20+ 657 203 30.9 398 272 68.3 6 1.5 73 18.3 37 9.3 10 2.5

Age at diagnosis <1 142 2 1.4 7 2 28.6 0 0.0 3 42.9 1 14.3 1 14.3

1-4 774 58 7.5 80 48 60.0 1 1.3 16 20.0 11 13.8 4 5.0

5-9 767 122 15.9 226 136 60.2 2 0.9 52 23.0 27 11.9 9 4.0

10-14 619 179 28.9 339 237 69.9 6 1.8 41 12.1 45 13.3 10 2.9

15-20 292 125 42.8 255 172 67.5 2 0.8 45 17.6 26 10.2 10 3.9

Treatment Surgery only 1004 265 26.4 492 328 66.7 5 1.0 82 16.7 65 13.2 12 2.4

Chemotherapy, no radiation 229 25 10.9 53 37 69.8 1 1.9 8 15.1 2 3.8 5 9.4

Radiation, no chemotherapy 704 124 17.6 231 146 63.2 4 1.7 43 18.6 27 11.7 11 4.8

Chemotherapy and radiation 403 28 6.9 53 35 66.0 0 0.0 8 15.1 7 13.2 3 5.7

Unknown 254 44 17.3 78 49 62.8 1 1.3 16 20.5 9 11.5 3 3.8

Males All cases 1354 203 15.0 348 249 71.6 2 0.6 48 13.8 36 10.3 13 3.7

Age at baseline <18 279 1 0.4 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

18-19 106 3 2.8 3 2 66.7 0 0.0 0 0.0 1 33.3 0 0.0

20-24 342 23 6.7 33 23 69.7 0 0.0 6 18.2 2 6.1 2 6.1

25-29 357 81 22.7 134 91 67.9 1 0.7 19 14.2 20 14.9 3 2.2

30-34 181 53 29.3 92 66 71.7 0 0.0 14 15.2 6 6.5 6 6.5

35+ 89 42 47.2 85 66 77.6 1 1.2 9 10.6 7 8.2 2 2.4

Years since diagnosis 5-9 125 7 5.6 14 9 64.3 0 0.0 3 21.4 1 7.1 1 7.1

10-14 477 39 8.2 56 41 73.2 0 0.0 5 8.9 8 14.3 2 3.6

15-19 404 70 17.3 109 74 67.9 0 0.0 17 15.6 13 11.9 5 4.6

20+ 348 87 25.0 169 125 74.0 2 1.2 23 13.6 14 8.3 5 3.0

Age at diagnosis <1 79 . . . . . . . . . . . . .

1-4 391 29 7.4 42 26 61.9 1 2.4 8 19.0 6 14.3 1 2.4

5-9 407 44 10.8 73 48 65.8 0 0.0 12 16.4 9 12.3 4 5.5

10-14 320 77 24.1 142 108 76.1 1 0.7 15 10.6 13 9.2 5 3.5

15-20 157 53 33.8 91 67 73.6 0 0.0 13 14.3 8 8.8 3 3.3

Treatment Surgery only 504 110 21.8 188 139 73.9 1 0.5 22 11.7 24 12.8 2 1.1

Chemotherapy, no radiation 127 15 11.8 30 23 76.7 1 3.3 3 10.0 1 3.3 2 6.7

Radiation, no chemotherapy 356 47 13.2 78 59 75.6 0 0.0 10 12.8 3 3.8 6 7.7

Chemotherapy and radiation 229 10 4.4 19 11 57.9 0 0.0 4 21.1 3 15.8 1 5.3

Unknown 138 21 15.2 33 17 51.5 0 0.0 9 27.3 5 15.2 2 6.1

Females All cases 1240 283 22.8 559 346 61.9 9 1.6 109 19.5 74 13.2 21 3.8

Age at baseline <18 248 . . . . . . . . . . . . .

Page 12: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Astrocytomas 12

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 105 2 1.9 2 1 50.0 0 0.0 1 50.0 0 0.0 0 0.0

20-24 348 57 16.4 91 44 48.4 2 2.2 23 25.3 14 15.4 8 8.8

25-29 277 88 31.8 158 92 58.2 1 0.6 28 17.7 30 19.0 7 4.4

30-34 182 89 48.9 199 136 68.3 2 1.0 36 18.1 20 10.1 5 2.5

35+ 80 47 58.8 109 73 67.0 4 3.7 21 19.3 10 9.2 1 0.9

Years since diagnosis 5-9 112 7 6.3 12 3 25.0 1 8.3 2 16.7 4 33.3 2 16.7

10-14 427 56 13.1 99 62 62.6 0 0.0 12 12.1 22 22.2 3 3.0

15-19 392 104 26.5 219 134 61.2 4 1.8 45 20.5 25 11.4 11 5.0

20+ 309 116 37.5 229 147 64.2 4 1.7 50 21.8 23 10.0 5 2.2

Age at diagnosis <1 63 2 3.2 7 2 28.6 0 0.0 3 42.9 1 14.3 1 14.3

1-4 383 29 7.6 38 22 57.9 0 0.0 8 21.1 5 13.2 3 7.9

5-9 360 78 21.7 153 88 57.5 2 1.3 40 26.1 18 11.8 5 3.3

10-14 299 102 34.1 197 129 65.5 5 2.5 26 13.2 32 16.2 5 2.5

15-20 135 72 53.3 164 105 64.0 2 1.2 32 19.5 18 11.0 7 4.3

Treatment Surgery only 500 155 31.0 304 189 62.2 4 1.3 60 19.7 41 13.5 10 3.3

Chemotherapy, no radiation 102 10 9.8 23 14 60.9 0 0.0 5 21.7 1 4.3 3 13.0

Radiation, no chemotherapy 348 77 22.1 153 87 56.9 4 2.6 33 21.6 24 15.7 5 3.3

Chemotherapy and radiation 174 18 10.3 34 24 70.6 0 0.0 4 11.8 4 11.8 2 5.9

Unknown 116 23 19.8 45 32 71.1 1 2.2 7 15.6 4 8.9 1 2.2

Page 13: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Medulloblastoma/PNET 13

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 997 64 6.4 98 66 67.3 0 0.0 11 11.2 14 14.3 7 7.1

Age at baseline <18 245 1 0.4 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

18-19 83 2 2.4 2 0 0.0 0 0.0 0 0.0 1 50.0 1 50.0

20-24 280 4 1.4 8 5 62.5 0 0.0 2 25.0 1 12.5 0 0.0

25-29 242 21 8.7 34 22 64.7 0 0.0 6 17.6 3 8.8 3 8.8

30-34 120 27 22.5 40 28 70.0 0 0.0 2 5.0 7 17.5 3 7.5

35+ 27 9 33.3 13 11 84.6 0 0.0 1 7.7 1 7.7 0 0.0

Years since diagnosis 5-9 123 . . . . . . . . . . . . .

10-14 354 12 3.4 17 8 47.1 0 0.0 3 17.6 3 17.6 3 17.6

15-19 329 32 9.7 46 28 60.9 0 0.0 5 10.9 9 19.6 4 8.7

20+ 191 20 10.5 35 30 85.7 0 0.0 3 8.6 2 5.7 0 0.0

Age at diagnosis <1 27 1 3.7 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

1-4 289 3 1.0 7 5 71.4 0 0.0 2 28.6 0 0.0 0 0.0

5-9 402 16 4.0 22 11 50.0 0 0.0 2 9.1 7 31.8 2 9.1

10-14 221 30 13.6 43 34 79.1 0 0.0 5 11.6 2 4.7 2 4.7

15-20 58 14 24.1 23 13 56.5 0 0.0 2 8.7 5 21.7 3 13.0

Treatment Surgery only 9 2 22.2 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy, no radiation 46 3 6.5 9 5 55.6 0 0.0 2 22.2 2 22.2 0 0.0

Radiation, no chemotherapy 201 21 10.4 33 26 78.8 0 0.0 3 9.1 3 9.1 1 3.0

Chemotherapy and radiation 672 33 4.9 45 26 57.8 0 0.0 5 11.1 8 17.8 6 13.3

Unknown 69 5 7.2 8 6 75.0 0 0.0 1 12.5 1 12.5 0 0.0

Males All cases 608 33 5.4 51 35 68.6 0 0.0 5 9.8 6 11.8 5 9.8

Age at baseline <18 147 . . . . . . . . . . . . .

18-19 47 1 2.1 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

20-24 178 2 1.1 3 0 0.0 0 0.0 2 66.7 1 33.3 0 0.0

25-29 152 9 5.9 14 9 64.3 0 0.0 2 14.3 1 7.1 2 14.3

30-34 68 15 22.1 23 17 73.9 0 0.0 0 0.0 3 13.0 3 13.0

35+ 16 6 37.5 10 9 90.0 0 0.0 1 10.0 0 0.0 0 0.0

Years since diagnosis 5-9 76 . . . . . . . . . . . . .

10-14 207 5 2.4 9 3 33.3 0 0.0 3 33.3 1 11.1 2 22.2

15-19 209 17 8.1 23 14 60.9 0 0.0 1 4.3 5 21.7 3 13.0

20+ 116 11 9.5 19 18 94.7 0 0.0 1 5.3 0 0.0 0 0.0

Age at diagnosis <1 15 . . . . . . . . . . . . .

1-4 176 2 1.1 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

5-9 255 9 3.5 12 7 58.3 0 0.0 1 8.3 3 25.0 1 8.3

10-14 127 14 11.0 20 15 75.0 0 0.0 3 15.0 1 5.0 1 5.0

15-20 35 8 22.9 16 10 62.5 0 0.0 1 6.3 2 12.5 3 18.8

Treatment Surgery only 6 2 33.3 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy, no radiation 22 1 4.5 2 0 0.0 0 0.0 0 0.0 2 100.0 0 0.0

Radiation, no chemotherapy 110 12 10.9 16 11 68.8 0 0.0 2 12.5 2 12.5 1 6.3

Chemotherapy and radiation 431 16 3.7 25 16 64.0 0 0.0 3 12.0 2 8.0 4 16.0

Unknown 39 2 5.1 5 5 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Females All cases 389 31 8.0 47 31 66.0 0 0.0 6 12.8 8 17.0 2 4.3

Age at baseline <18 98 1 1.0 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

Page 14: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Medulloblastoma/PNET 14

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 36 1 2.8 1 0 0.0 0 0.0 0 0.0 0 0.0 1 100.0

20-24 102 2 2.0 5 5 100.0 0 0.0 0 0.0 0 0.0 0 0.0

25-29 90 12 13.3 20 13 65.0 0 0.0 4 20.0 2 10.0 1 5.0

30-34 52 12 23.1 17 11 64.7 0 0.0 2 11.8 4 23.5 0 0.0

35+ 11 3 27.3 3 2 66.7 0 0.0 0 0.0 1 33.3 0 0.0

Years since diagnosis 5-9 47 . . . . . . . . . . . . .

10-14 147 7 4.8 8 5 62.5 0 0.0 0 0.0 2 25.0 1 12.5

15-19 120 15 12.5 23 14 60.9 0 0.0 4 17.4 4 17.4 1 4.3

20+ 75 9 12.0 16 12 75.0 0 0.0 2 12.5 2 12.5 0 0.0

Age at diagnosis <1 12 1 8.3 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

1-4 113 1 0.9 4 2 50.0 0 0.0 2 50.0 0 0.0 0 0.0

5-9 147 7 4.8 10 4 40.0 0 0.0 1 10.0 4 40.0 1 10.0

10-14 94 16 17.0 23 19 82.6 0 0.0 2 8.7 1 4.3 1 4.3

15-20 23 6 26.1 7 3 42.9 0 0.0 1 14.3 3 42.9 0 0.0

Treatment Surgery only 3 . . . . . . . . . . . . .

Chemotherapy, no radiation 24 2 8.3 7 5 71.4 0 0.0 2 28.6 0 0.0 0 0.0

Radiation, no chemotherapy 91 9 9.9 17 15 88.2 0 0.0 1 5.9 1 5.9 0 0.0

Chemotherapy and radiation 241 17 7.1 20 10 50.0 0 0.0 2 10.0 6 30.0 2 10.0

Unknown 30 3 10.0 3 1 33.3 0 0.0 1 33.3 1 33.3 0 0.0

Page 15: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Hodgkin

Pregnancies in female survivors or female partners of male survivors

15

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 2996 1234 41.2 2791 1902 68.1 30 1.1 425 15.2 335 12.0 99 3.5

Age at baseline <18 61 1 1.6 1 0 0.0 0 0.0 0 0.0 0 0.0 1 100.0

18-19 62 6 9.7 7 3 42.9 0 0.0 4 57.1 0 0.0 0 0.0

20-24 372 66 17.7 103 57 55.3 0 0.0 13 12.6 24 23.3 9 8.7

25-29 783 282 36.0 553 352 63.7 8 1.4 80 14.5 68 12.3 45 8.1

30-34 912 417 45.7 946 663 70.1 6 0.6 136 14.4 118 12.5 23 2.4

35+ 806 462 57.3 1181 827 70.0 16 1.4 192 16.3 125 10.6 21 1.8

Years since diagnosis 5-9 242 49 20.2 81 42 51.9 0 0.0 12 14.8 10 12.3 17 21.0

10-14 947 324 34.2 648 417 64.4 7 1.1 95 14.7 95 14.7 34 5.2

15-19 967 447 46.2 1011 711 70.3 11 1.1 147 14.5 108 10.7 34 3.4

20+ 840 414 49.3 1051 732 69.6 12 1.1 171 16.3 122 11.6 14 1.3

Age at diagnosis 1-4 79 11 13.9 16 7 43.8 0 0.0 3 18.8 5 31.3 1 6.3

5-9 404 89 22.0 174 105 60.3 0 0.0 34 19.5 25 14.4 10 5.7

10-14 1075 418 38.9 975 668 68.5 15 1.5 142 14.6 122 12.5 28 2.9

15-20 1438 716 49.8 1626 1122 69.0 15 0.9 246 15.1 183 11.3 60 3.7

Treatment Surgery only 2 . . . . . . . . . . . . .

Chemotherapy, no radiation 327 122 37.3 307 197 64.2 3 1.0 55 17.9 41 13.4 11 3.6

Radiation, no chemotherapy 626 344 55.0 782 531 67.9 12 1.5 116 14.8 101 12.9 22 2.8

Chemotherapy and radiation 1750 649 37.1 1428 983 68.8 15 1.1 214 15.0 164 11.5 52 3.6

Unknown 291 119 40.9 274 191 69.7 0 0.0 40 14.6 29 10.6 14 5.1

Males All cases 1576 420 26.6 856 596 69.6 8 0.9 123 14.4 81 9.5 48 5.6

Age at baseline <18 46 1 2.2 1 0 0.0 0 0.0 0 0.0 0 0.0 1 100.0

18-19 49 5 10.2 6 2 33.3 0 0.0 4 66.7 0 0.0 0 0.0

20-24 238 28 11.8 44 20 45.5 0 0.0 6 13.6 11 25.0 7 15.9

25-29 437 94 21.5 165 100 60.6 2 1.2 28 17.0 19 11.5 16 9.7

30-34 458 141 30.8 283 209 73.9 0 0.0 38 13.4 22 7.8 14 4.9

35+ 348 151 43.4 357 265 74.2 6 1.7 47 13.2 29 8.1 10 2.8

Years since diagnosis 5-9 138 15 10.9 23 9 39.1 0 0.0 4 17.4 3 13.0 7 30.4

10-14 493 97 19.7 164 102 62.2 1 0.6 31 18.9 17 10.4 13 7.9

15-19 515 151 29.3 306 223 72.9 1 0.3 38 12.4 22 7.2 22 7.2

20+ 430 157 36.5 363 262 72.2 6 1.7 50 13.8 39 10.7 6 1.7

Age at diagnosis 1-4 61 8 13.1 11 3 27.3 0 0.0 2 18.2 5 45.5 1 9.1

5-9 297 52 17.5 97 54 55.7 0 0.0 17 17.5 17 17.5 9 9.3

10-14 558 127 22.8 264 189 71.6 2 0.8 45 17.0 18 6.8 10 3.8

15-20 660 233 35.3 484 350 72.3 6 1.2 59 12.2 41 8.5 28 5.8

Treatment Surgery only 2 . . . . . . . . . . . . .

Chemotherapy, no radiation 168 40 23.8 97 66 68.0 1 1.0 18 18.6 8 8.2 4 4.1

Radiation, no chemotherapy 323 140 43.3 302 212 70.2 3 1.0 43 14.2 35 11.6 9 3.0

Chemotherapy and radiation 906 191 21.1 365 256 70.1 4 1.1 50 13.7 28 7.7 27 7.4

Unknown 177 49 27.7 92 62 67.4 0 0.0 12 13.0 10 10.9 8 8.7

Females All cases 1420 814 57.3 1935 1306 67.5 22 1.1 302 15.6 254 13.1 51 2.6

Age at baseline <18 15 . . . . . . . . . . . . .

18-19 13 1 7.7 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

20-24 134 38 28.4 59 37 62.7 0 0.0 7 11.9 13 22.0 2 3.4

Page 16: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Hodgkin

Pregnancies in female survivors or female partners of male survivors

16

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

25-29 346 188 54.3 388 252 64.9 6 1.5 52 13.4 49 12.6 29 7.5

30-34 454 276 60.8 663 454 68.5 6 0.9 98 14.8 96 14.5 9 1.4

35+ 458 311 67.9 824 562 68.2 10 1.2 145 17.6 96 11.7 11 1.3

Years since diagnosis 5-9 104 34 32.7 58 33 56.9 0 0.0 8 13.8 7 12.1 10 17.2

10-14 454 227 50.0 484 315 65.1 6 1.2 64 13.2 78 16.1 21 4.3

15-19 452 296 65.5 705 488 69.2 10 1.4 109 15.5 86 12.2 12 1.7

20+ 410 257 62.7 688 470 68.3 6 0.9 121 17.6 83 12.1 8 1.2

Age at diagnosis 1-4 18 3 16.7 5 4 80.0 0 0.0 1 20.0 0 0.0 0 0.0

5-9 107 37 34.6 77 51 66.2 0 0.0 17 22.1 8 10.4 1 1.3

10-14 517 291 56.3 711 479 67.4 13 1.8 97 13.6 104 14.6 18 2.5

15-20 778 483 62.1 1142 772 67.6 9 0.8 187 16.4 142 12.4 32 2.8

Treatment Chemotherapy, no radiation 159 82 51.6 210 131 62.4 2 1.0 37 17.6 33 15.7 7 3.3

Radiation, no chemotherapy 303 204 67.3 480 319 66.5 9 1.9 73 15.2 66 13.8 13 2.7

Chemotherapy and radiation 844 458 54.3 1063 727 68.4 11 1.0 164 15.4 136 12.8 25 2.4

Unknown 114 70 61.4 182 129 70.9 0 0.0 28 15.4 19 10.4 6 3.3

Page 17: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: NHL

Pregnancies in female survivors or female partners of male survivors

17

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 1987 613 30.9 1304 894 68.6 13 1.0 199 15.3 148 11.3 50 3.8

Age at baseline <18 212 . . . . . . . . . . . . .

18-19 131 2 1.5 2 0 0.0 0 0.0 1 50.0 1 50.0 0 0.0

20-24 459 76 16.6 118 63 53.4 0 0.0 22 18.6 22 18.6 11 9.3

25-29 534 191 35.8 364 250 68.7 6 1.6 51 14.0 36 9.9 21 5.8

30-34 441 206 46.7 464 342 73.7 4 0.9 59 12.7 51 11.0 8 1.7

35+ 210 138 65.7 356 239 67.1 3 0.8 66 18.5 38 10.7 10 2.8

Years since diagnosis 5-9 144 5 3.5 7 4 57.1 0 0.0 1 14.3 2 28.6 0 0.0

10-14 673 154 22.9 290 192 66.2 2 0.7 44 15.2 39 13.4 13 4.5

15-19 684 235 34.4 479 354 73.9 6 1.3 59 12.3 44 9.2 16 3.3

20+ 486 219 45.1 528 344 65.2 5 0.9 95 18.0 63 11.9 21 4.0

Age at diagnosis <1 15 . . . . . . . . . . . . .

1-4 327 30 9.2 61 29 47.5 1 1.6 14 23.0 10 16.4 7 11.5

5-9 601 126 21.0 237 152 64.1 3 1.3 40 16.9 28 11.8 14 5.9

10-14 635 241 38.0 528 367 69.5 2 0.4 78 14.8 62 11.7 19 3.6

15-20 409 216 52.8 478 346 72.4 7 1.5 67 14.0 48 10.0 10 2.1

Treatment Surgery only 15 5 33.3 7 7 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy, no radiation 983 315 32.0 627 434 69.2 2 0.3 89 14.2 67 10.7 35 5.6

Radiation, no chemotherapy 37 24 64.9 67 48 71.6 3 4.5 12 17.9 4 6.0 0 0.0

Chemotherapy and radiation 759 209 27.5 453 306 67.5 6 1.3 72 15.9 57 12.6 12 2.6

Unknown 193 60 31.1 150 99 66.0 2 1.3 26 17.3 20 13.3 3 2.0

Males All cases 1346 349 25.9 690 495 71.7 5 0.7 91 13.2 72 10.4 27 3.9

Age at baseline <18 146 . . . . . . . . . . . . .

18-19 96 1 1.0 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

20-24 298 28 9.4 38 17 44.7 0 0.0 6 15.8 9 23.7 6 15.8

25-29 379 112 29.6 198 143 72.2 2 1.0 28 14.1 15 7.6 10 5.1

30-34 288 120 41.7 229 183 79.9 1 0.4 17 7.4 24 10.5 4 1.7

35+ 139 88 63.3 224 152 67.9 2 0.9 40 17.9 23 10.3 7 3.1

Years since diagnosis 5-9 109 3 2.8 4 3 75.0 0 0.0 0 0.0 1 25.0 0 0.0

10-14 458 80 17.5 144 103 71.5 0 0.0 19 13.2 16 11.1 6 4.2

15-19 445 128 28.8 231 177 76.6 2 0.9 25 10.8 18 7.8 9 3.9

20+ 334 138 41.3 311 212 68.2 3 1.0 47 15.1 37 11.9 12 3.9

Age at diagnosis <1 5 . . . . . . . . . . . . .

1-4 221 12 5.4 22 13 59.1 0 0.0 3 13.6 4 18.2 2 9.1

5-9 421 67 15.9 110 69 62.7 3 2.7 18 16.4 11 10.0 9 8.2

10-14 431 138 32.0 269 202 75.1 0 0.0 26 9.7 30 11.2 11 4.1

15-20 268 132 49.3 289 211 73.0 2 0.7 44 15.2 27 9.3 5 1.7

Treatment Surgery only 12 5 41.7 7 7 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy, no radiation 663 183 27.6 348 244 70.1 1 0.3 44 12.6 40 11.5 19 5.5

Radiation, no chemotherapy 28 17 60.7 43 37 86.0 2 4.7 3 7.0 1 2.3 0 0.0

Chemotherapy and radiation 506 109 21.5 212 152 71.7 0 0.0 31 14.6 22 10.4 7 3.3

Unknown 137 35 25.5 80 55 68.8 2 2.5 13 16.3 9 11.3 1 1.3

Females All cases 641 264 41.2 614 399 65.0 8 1.3 108 17.6 76 12.4 23 3.7

Age at baseline <18 66 . . . . . . . . . . . . .

Page 18: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: NHL

Pregnancies in female survivors or female partners of male survivors

18

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 35 1 2.9 1 0 0.0 0 0.0 1 100.0 0 0.0 0 0.0

20-24 161 48 29.8 80 46 57.5 0 0.0 16 20.0 13 16.3 5 6.3

25-29 155 79 51.0 166 107 64.5 4 2.4 23 13.9 21 12.7 11 6.6

30-34 153 86 56.2 235 159 67.7 3 1.3 42 17.9 27 11.5 4 1.7

35+ 71 50 70.4 132 87 65.9 1 0.8 26 19.7 15 11.4 3 2.3

Years since diagnosis 5-9 35 2 5.7 3 1 33.3 0 0.0 1 33.3 1 33.3 0 0.0

10-14 215 74 34.4 146 89 61.0 2 1.4 25 17.1 23 15.8 7 4.8

15-19 239 107 44.8 248 177 71.4 4 1.6 34 13.7 26 10.5 7 2.8

20+ 152 81 53.3 217 132 60.8 2 0.9 48 22.1 26 12.0 9 4.1

Age at diagnosis <1 10 . . . . . . . . . . . . .

1-4 106 18 17.0 39 16 41.0 1 2.6 11 28.2 6 15.4 5 12.8

5-9 180 59 32.8 127 83 65.4 0 0.0 22 17.3 17 13.4 5 3.9

10-14 204 103 50.5 259 165 63.7 2 0.8 52 20.1 32 12.4 8 3.1

15-20 141 84 59.6 189 135 71.4 5 2.6 23 12.2 21 11.1 5 2.6

Treatment Surgery only 3 . . . . . . . . . . . . .

Chemotherapy, no radiation 320 132 41.3 279 190 68.1 1 0.4 45 16.1 27 9.7 16 5.7

Radiation, no chemotherapy 9 7 77.8 24 11 45.8 1 4.2 9 37.5 3 12.5 0 0.0

Chemotherapy and radiation 253 100 39.5 241 154 63.9 6 2.5 41 17.0 35 14.5 5 2.1

Unknown 56 25 44.6 70 44 62.9 0 0.0 13 18.6 11 15.7 2 2.9

Page 19: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Wilms

Pregnancies in female survivors or female partners of male survivors

19

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 2159 329 15.2 596 339 56.9 9 1.5 106 17.8 101 16.9 41 6.9

Age at baseline <18 825 9 1.1 11 3 27.3 0 0.0 1 9.1 1 9.1 6 54.5

18-19 297 26 8.8 37 16 43.2 1 2.7 8 21.6 12 32.4 0 0.0

20-24 639 124 19.4 202 115 56.9 2 1.0 41 20.3 29 14.4 15 7.4

25-29 327 125 38.2 248 144 58.1 6 2.4 47 19.0 36 14.5 15 6.0

30-34 57 38 66.7 76 48 63.2 0 0.0 7 9.2 16 21.1 5 6.6

35+ 14 7 50.0 22 13 59.1 0 0.0 2 9.1 7 31.8 0 0.0

Years since diagnosis 5-9 175 1 0.6 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

10-14 738 28 3.8 50 21 42.0 1 2.0 8 16.0 16 32.0 4 8.0

15-19 722 113 15.7 179 105 58.7 1 0.6 34 19.0 29 16.2 10 5.6

20+ 524 187 35.7 366 212 57.9 7 1.9 64 17.5 56 15.3 27 7.4

Age at diagnosis <1 313 26 8.3 42 23 54.8 1 2.4 9 21.4 4 9.5 5 11.9

1-4 1326 173 13.0 309 173 56.0 5 1.6 62 20.1 49 15.9 20 6.5

5-9 444 98 22.1 174 98 56.3 3 1.7 28 16.1 29 16.7 16 9.2

10-14 53 21 39.6 44 29 65.9 0 0.0 5 11.4 10 22.7 0 0.0

15-20 23 11 47.8 27 16 59.3 0 0.0 2 7.4 9 33.3 0 0.0

Treatment Surgery only 31 3 9.7 7 3 42.9 0 0.0 0 0.0 4 57.1 0 0.0

Chemotherapy, no radiation 804 95 11.8 167 100 59.9 1 0.6 27 16.2 26 15.6 13 7.8

Radiation, no chemotherapy 4 2 50.0 2 0 0.0 0 0.0 1 50.0 0 0.0 1 50.0

Chemotherapy and radiation 1117 179 16.0 323 182 56.3 6 1.9 63 19.5 54 16.7 18 5.6

Unknown 203 50 24.6 97 54 55.7 2 2.1 15 15.5 17 17.5 9 9.3

Males All cases 970 109 11.2 193 109 56.5 3 1.6 31 16.1 35 18.1 15 7.8

Age at baseline <18 400 3 0.8 3 1 33.3 0 0.0 0 0.0 0 0.0 2 66.7

18-19 124 7 5.6 9 4 44.4 0 0.0 1 11.1 4 44.4 0 0.0

20-24 271 35 12.9 55 27 49.1 0 0.0 17 30.9 6 10.9 5 9.1

25-29 146 44 30.1 80 49 61.3 3 3.8 8 10.0 15 18.8 5 6.3

30-34 24 18 75.0 41 23 56.1 0 0.0 5 12.2 10 24.4 3 7.3

35+ 5 2 40.0 5 5 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Years since diagnosis 5-9 77 . . . . . . . . . . . . .

10-14 334 7 2.1 9 5 55.6 0 0.0 0 0.0 2 22.2 2 22.2

15-19 321 28 8.7 44 22 50.0 0 0.0 11 25.0 10 22.7 1 2.3

20+ 238 74 31.1 140 82 58.6 3 2.1 20 14.3 23 16.4 12 8.6

Age at diagnosis <1 163 8 4.9 13 6 46.2 1 7.7 2 15.4 1 7.7 3 23.1

1-4 597 57 9.5 104 56 53.8 1 1.0 20 19.2 19 18.3 8 7.7

5-9 181 34 18.8 56 32 57.1 1 1.8 7 12.5 12 21.4 4 7.1

10-14 20 8 40.0 17 13 76.5 0 0.0 2 11.8 2 11.8 0 0.0

15-20 9 2 22.2 3 2 66.7 0 0.0 0 0.0 1 33.3 0 0.0

Treatment Surgery only 17 . . . . . . . . . . . . .

Chemotherapy, no radiation 370 33 8.9 59 31 52.5 1 1.7 9 15.3 12 20.3 6 10.2

Chemotherapy and radiation 481 55 11.4 99 61 61.6 1 1.0 17 17.2 16 16.2 4 4.0

Unknown 102 21 20.6 35 17 48.6 1 2.9 5 14.3 7 20.0 5 14.3

Females All cases 1189 220 18.5 403 230 57.1 6 1.5 75 18.6 66 16.4 26 6.5

Age at baseline <18 425 6 1.4 8 2 25.0 0 0.0 1 12.5 1 12.5 4 50.0

18-19 173 19 11.0 28 12 42.9 1 3.6 7 25.0 8 28.6 0 0.0

Page 20: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Wilms

Pregnancies in female survivors or female partners of male survivors

20

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

20-24 368 89 24.2 147 88 59.9 2 1.4 24 16.3 23 15.6 10 6.8

25-29 181 81 44.8 168 95 56.5 3 1.8 39 23.2 21 12.5 10 6.0

30-34 33 20 60.6 35 25 71.4 0 0.0 2 5.7 6 17.1 2 5.7

35+ 9 5 55.6 17 8 47.1 0 0.0 2 11.8 7 41.2 0 0.0

Years since diagnosis 5-9 98 1 1.0 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

10-14 404 21 5.2 41 16 39.0 1 2.4 8 19.5 14 34.1 2 4.9

15-19 401 85 21.2 135 83 61.5 1 0.7 23 17.0 19 14.1 9 6.7

20+ 286 113 39.5 226 130 57.5 4 1.8 44 19.5 33 14.6 15 6.6

Age at diagnosis <1 150 18 12.0 29 17 58.6 0 0.0 7 24.1 3 10.3 2 6.9

1-4 729 116 15.9 205 117 57.1 4 2.0 42 20.5 30 14.6 12 5.9

5-9 263 64 24.3 118 66 55.9 2 1.7 21 17.8 17 14.4 12 10.2

10-14 33 13 39.4 27 16 59.3 0 0.0 3 11.1 8 29.6 0 0.0

15-20 14 9 64.3 24 14 58.3 0 0.0 2 8.3 8 33.3 0 0.0

Treatment Surgery only 14 3 21.4 7 3 42.9 0 0.0 0 0.0 4 57.1 0 0.0

Chemotherapy, no radiation 434 62 14.3 108 69 63.9 0 0.0 18 16.7 14 13.0 7 6.5

Radiation, no chemotherapy 4 2 50.0 2 0 0.0 0 0.0 1 50.0 0 0.0 1 50.0

Chemotherapy and radiation 636 124 19.5 224 121 54.0 5 2.2 46 20.5 38 17.0 14 6.3

Unknown 101 29 28.7 62 37 59.7 1 1.6 10 16.1 10 16.1 4 6.5

Page 21: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Neuroblastoma

Pregnancies in female survivors or female partners of male survivors

21

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 1852 181 9.8 316 183 57.9 0 0.0 52 16.5 58 18.4 23 7.3

Age at baseline <18 942 10 1.1 12 5 41.7 0 0.0 0 0.0 1 8.3 6 50.0

18-19 228 22 9.6 32 18 56.3 0 0.0 6 18.8 6 18.8 2 6.3

20-24 503 83 16.5 141 81 57.4 0 0.0 24 17.0 25 17.7 11 7.8

25-29 141 47 33.3 87 49 56.3 0 0.0 16 18.4 18 20.7 4 4.6

30-34 32 16 50.0 38 24 63.2 0 0.0 6 15.8 8 21.1 0 0.0

35+ 6 3 50.0 6 6 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Years since diagnosis 5-9 159 . . . . . . . . . . . . .

10-14 606 10 1.7 17 9 52.9 0 0.0 2 11.8 3 17.6 3 17.6

15-19 607 56 9.2 93 46 49.5 0 0.0 16 17.2 19 20.4 12 12.9

20+ 480 115 24.0 206 128 62.1 0 0.0 34 16.5 36 17.5 8 3.9

Age at diagnosis <1 950 69 7.3 120 69 57.5 0 0.0 19 15.8 24 20.0 8 6.7

1-4 716 77 10.8 124 72 58.1 0 0.0 21 16.9 20 16.1 11 8.9

5-9 140 22 15.7 46 24 52.2 0 0.0 9 19.6 10 21.7 3 6.5

10-14 28 7 25.0 13 7 53.8 0 0.0 3 23.1 2 15.4 1 7.7

15-20 18 6 33.3 13 11 84.6 0 0.0 0 0.0 2 15.4 0 0.0

Treatment Surgery only 514 58 11.3 94 54 57.4 0 0.0 17 18.1 14 14.9 9 9.6

Chemotherapy, no radiation 527 32 6.1 61 36 59.0 0 0.0 14 23.0 7 11.5 4 6.6

Radiation, no chemotherapy 138 21 15.2 32 20 62.5 0 0.0 2 6.3 7 21.9 3 9.4

Chemotherapy and radiation 510 47 9.2 82 40 48.8 0 0.0 11 13.4 25 30.5 6 7.3

Unknown 163 23 14.1 47 33 70.2 0 0.0 8 17.0 5 10.6 1 2.1

Males All cases 904 44 4.9 67 42 62.7 0 0.0 9 13.4 15 22.4 1 1.5

Age at baseline <18 469 . . . . . . . . . . . . .

18-19 100 4 4.0 5 3 60.0 0 0.0 0 0.0 2 40.0 0 0.0

20-24 253 22 8.7 32 18 56.3 0 0.0 6 18.8 7 21.9 1 3.1

25-29 66 14 21.2 22 16 72.7 0 0.0 2 9.1 4 18.2 0 0.0

30-34 13 3 23.1 6 3 50.0 0 0.0 1 16.7 2 33.3 0 0.0

35+ 3 1 33.3 2 2 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Years since diagnosis 5-9 75 . . . . . . . . . . . . .

10-14 302 1 0.3 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

15-19 288 11 3.8 13 9 69.2 0 0.0 1 7.7 2 15.4 1 7.7

20+ 239 32 13.4 53 32 60.4 0 0.0 8 15.1 13 24.5 0 0.0

Age at diagnosis <1 496 23 4.6 37 20 54.1 0 0.0 6 16.2 11 29.7 0 0.0

1-4 318 11 3.5 15 11 73.3 0 0.0 2 13.3 1 6.7 1 6.7

5-9 71 7 9.9 11 7 63.6 0 0.0 1 9.1 3 27.3 0 0.0

10-14 13 2 15.4 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

15-20 6 1 16.7 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Treatment Surgery only 248 14 5.6 23 10 43.5 0 0.0 4 17.4 9 39.1 0 0.0

Chemotherapy, no radiation 262 5 1.9 5 4 80.0 0 0.0 1 20.0 0 0.0 0 0.0

Radiation, no chemotherapy 62 5 8.1 8 5 62.5 0 0.0 1 12.5 2 25.0 0 0.0

Chemotherapy and radiation 247 11 4.5 15 10 66.7 0 0.0 2 13.3 2 13.3 1 6.7

Unknown 85 9 10.6 16 13 81.3 0 0.0 1 6.3 2 12.5 0 0.0

Females All cases 948 137 14.5 249 141 56.6 0 0.0 43 17.3 43 17.3 22 8.8

Age at baseline <18 473 10 2.1 12 5 41.7 0 0.0 0 0.0 1 8.3 6 50.0

Page 22: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Neuroblastoma

Pregnancies in female survivors or female partners of male survivors

22

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 128 18 14.1 27 15 55.6 0 0.0 6 22.2 4 14.8 2 7.4

20-24 250 61 24.4 109 63 57.8 0 0.0 18 16.5 18 16.5 10 9.2

25-29 75 33 44.0 65 33 50.8 0 0.0 14 21.5 14 21.5 4 6.2

30-34 19 13 68.4 32 21 65.6 0 0.0 5 15.6 6 18.8 0 0.0

35+ 3 2 66.7 4 4 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Years since diagnosis 5-9 84 . . . . . . . . . . . . .

10-14 304 9 3.0 16 8 50.0 0 0.0 2 12.5 3 18.8 3 18.8

15-19 319 45 14.1 80 37 46.3 0 0.0 15 18.8 17 21.3 11 13.8

20+ 241 83 34.4 153 96 62.7 0 0.0 26 17.0 23 15.0 8 5.2

Age at diagnosis <1 454 46 10.1 83 49 59.0 0 0.0 13 15.7 13 15.7 8 9.6

1-4 398 66 16.6 109 61 56.0 0 0.0 19 17.4 19 17.4 10 9.2

5-9 69 15 21.7 35 17 48.6 0 0.0 8 22.9 7 20.0 3 8.6

10-14 15 5 33.3 10 4 40.0 0 0.0 3 30.0 2 20.0 1 10.0

15-20 12 5 41.7 12 10 83.3 0 0.0 0 0.0 2 16.7 0 0.0

Treatment Surgery only 266 44 16.5 71 44 62.0 0 0.0 13 18.3 5 7.0 9 12.7

Chemotherapy, no radiation 265 27 10.2 56 32 57.1 0 0.0 13 23.2 7 12.5 4 7.1

Radiation, no chemotherapy 76 16 21.1 24 15 62.5 0 0.0 1 4.2 5 20.8 3 12.5

Chemotherapy and radiation 263 36 13.7 67 30 44.8 0 0.0 9 13.4 23 34.3 5 7.5

Unknown 78 14 17.9 31 20 64.5 0 0.0 7 22.6 3 9.7 1 3.2

Page 23: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: STS

Pregnancies in female survivors or female partners of male survivors

23

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 1706 441 25.8 944 627 66.4 9 1.0 143 15.1 129 13.7 36 3.8

Age at baseline <18 339 1 0.3 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

18-19 122 8 6.6 10 5 50.0 0 0.0 2 20.0 2 20.0 1 10.0

20-24 412 66 16.0 105 60 57.1 0 0.0 18 17.1 24 22.9 3 2.9

25-29 377 119 31.6 235 136 57.9 1 0.4 39 16.6 38 16.2 21 8.9

30-34 282 131 46.5 296 220 74.3 2 0.7 35 11.8 30 10.1 9 3.0

35+ 174 116 66.7 297 205 69.0 6 2.0 49 16.5 35 11.8 2 0.7

Years since diagnosis 5-9 181 24 13.3 42 21 50.0 0 0.0 6 14.3 4 9.5 11 26.2

10-14 521 87 16.7 161 107 66.5 2 1.2 19 11.8 27 16.8 6 3.7

15-19 525 147 28.0 319 213 66.8 1 0.3 47 14.7 49 15.4 9 2.8

20+ 479 183 38.2 422 286 67.8 6 1.4 71 16.8 49 11.6 10 2.4

Age at diagnosis <1 119 7 5.9 12 7 58.3 0 0.0 2 16.7 3 25.0 0 0.0

1-4 535 49 9.2 85 48 56.5 0 0.0 14 16.5 18 21.2 5 5.9

5-9 387 82 21.2 161 106 65.8 1 0.6 28 17.4 23 14.3 3 1.9

10-14 338 127 37.6 268 187 69.8 2 0.7 40 14.9 30 11.2 9 3.4

15-20 327 176 53.8 418 279 66.7 6 1.4 59 14.1 55 13.2 19 4.5

Treatment Surgery only 167 80 47.9 213 143 67.1 4 1.9 38 17.8 23 10.8 5 2.3

Chemotherapy, no radiation 346 98 28.3 196 121 61.7 1 0.5 31 15.8 36 18.4 7 3.6

Radiation, no chemotherapy 60 29 48.3 69 44 63.8 1 1.4 10 14.5 13 18.8 1 1.4

Chemotherapy and radiation 959 181 18.9 356 245 68.8 1 0.3 53 14.9 45 12.6 12 3.4

Unknown 174 53 30.5 110 74 67.3 2 1.8 11 10.0 12 10.9 11 10.0

Males All cases 922 164 17.8 348 248 71.3 4 1.1 48 13.8 33 9.5 15 4.3

Age at baseline <18 191 . . . . . . . . . . . . .

18-19 66 5 7.6 6 1 16.7 0 0.0 2 33.3 2 33.3 1 16.7

20-24 233 23 9.9 34 22 64.7 0 0.0 4 11.8 8 23.5 0 0.0

25-29 199 33 16.6 58 36 62.1 0 0.0 10 17.2 6 10.3 6 10.3

30-34 150 52 34.7 119 93 78.2 1 0.8 12 10.1 7 5.9 6 5.0

35+ 83 51 61.4 131 96 73.3 3 2.3 20 15.3 10 7.6 2 1.5

Years since diagnosis 5-9 100 6 6.0 12 7 58.3 0 0.0 1 8.3 0 0.0 4 33.3

10-14 288 25 8.7 51 37 72.5 0 0.0 6 11.8 6 11.8 2 3.9

15-19 271 57 21.0 109 81 74.3 1 0.9 13 11.9 9 8.3 5 4.6

20+ 263 76 28.9 176 123 69.9 3 1.7 28 15.9 18 10.2 4 2.3

Age at diagnosis <1 51 3 5.9 3 1 33.3 0 0.0 1 33.3 1 33.3 0 0.0

1-4 318 21 6.6 33 19 57.6 0 0.0 5 15.2 7 21.2 2 6.1

5-9 216 31 14.4 60 41 68.3 1 1.7 10 16.7 8 13.3 0 0.0

10-14 181 41 22.7 86 64 74.4 1 1.2 11 12.8 7 8.1 3 3.5

15-20 156 68 43.6 166 123 74.1 2 1.2 21 12.7 10 6.0 10 6.0

Treatment Surgery only 74 31 41.9 87 63 72.4 1 1.1 13 14.9 7 8.0 3 3.4

Chemotherapy, no radiation 201 44 21.9 78 53 67.9 0 0.0 10 12.8 13 16.7 2 2.6

Radiation, no chemotherapy 30 12 40.0 31 20 64.5 1 3.2 7 22.6 2 6.5 1 3.2

Chemotherapy and radiation 515 55 10.7 108 81 75.0 1 0.9 13 12.0 9 8.3 4 3.7

Unknown 102 22 21.6 44 31 70.5 1 2.3 5 11.4 2 4.5 5 11.4

Females All cases 784 277 35.3 596 379 63.6 5 0.8 95 15.9 96 16.1 21 3.5

Age at baseline <18 148 1 0.7 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Page 24: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: STS

Pregnancies in female survivors or female partners of male survivors

24

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 56 3 5.4 4 4 100.0 0 0.0 0 0.0 0 0.0 0 0.0

20-24 179 43 24.0 71 38 53.5 0 0.0 14 19.7 16 22.5 3 4.2

25-29 178 86 48.3 177 100 56.5 1 0.6 29 16.4 32 18.1 15 8.5

30-34 132 79 59.8 177 127 71.8 1 0.6 23 13.0 23 13.0 3 1.7

35+ 91 65 71.4 166 109 65.7 3 1.8 29 17.5 25 15.1 0 0.0

Years since diagnosis 5-9 81 18 22.2 30 14 46.7 0 0.0 5 16.7 4 13.3 7 23.3

10-14 233 62 26.6 110 70 63.6 2 1.8 13 11.8 21 19.1 4 3.6

15-19 254 90 35.4 210 132 62.9 0 0.0 34 16.2 40 19.0 4 1.9

20+ 216 107 49.5 246 163 66.3 3 1.2 43 17.5 31 12.6 6 2.4

Age at diagnosis <1 68 4 5.9 9 6 66.7 0 0.0 1 11.1 2 22.2 0 0.0

1-4 217 28 12.9 52 29 55.8 0 0.0 9 17.3 11 21.2 3 5.8

5-9 171 51 29.8 101 65 64.4 0 0.0 18 17.8 15 14.9 3 3.0

10-14 157 86 54.8 182 123 67.6 1 0.5 29 15.9 23 12.6 6 3.3

15-20 171 108 63.2 252 156 61.9 4 1.6 38 15.1 45 17.9 9 3.6

Treatment Surgery only 93 49 52.7 126 80 63.5 3 2.4 25 19.8 16 12.7 2 1.6

Chemotherapy, no radiation 145 54 37.2 118 68 57.6 1 0.8 21 17.8 23 19.5 5 4.2

Radiation, no chemotherapy 30 17 56.7 38 24 63.2 0 0.0 3 7.9 11 28.9 0 0.0

Chemotherapy and radiation 444 126 28.4 248 164 66.1 0 0.0 40 16.1 36 14.5 8 3.2

Unknown 72 31 43.1 66 43 65.2 1 1.5 6 9.1 10 15.2 6 9.1

Page 25: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: All bone

Pregnancies in female survivors or female partners of male survivors

25

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 2017 748 37.1 1644 1081 65.8 14 0.9 267 16.2 207 12.6 75 4.6

Age at baseline <18 96 2 2.1 3 1 33.3 0 0.0 0 0.0 2 66.7 0 0.0

18-19 72 2 2.8 3 1 33.3 0 0.0 1 33.3 0 0.0 1 33.3

20-24 383 68 17.8 118 66 55.9 3 2.5 18 15.3 19 16.1 12 10.2

25-29 552 177 32.1 322 209 64.9 2 0.6 47 14.6 38 11.8 26 8.1

30-34 538 265 49.3 623 411 66.0 5 0.8 99 15.9 81 13.0 27 4.3

35+ 376 234 62.2 575 393 68.3 4 0.7 102 17.7 67 11.7 9 1.6

Years since diagnosis 5-9 241 24 10.0 35 21 60.0 0 0.0 3 8.6 6 17.1 5 14.3

10-14 676 193 28.6 366 231 63.1 6 1.6 55 15.0 54 14.8 20 5.5

15-19 641 273 42.6 607 401 66.1 6 1.0 92 15.2 73 12.0 35 5.8

20+ 459 258 56.2 636 428 67.3 2 0.3 117 18.4 74 11.6 15 2.4

Age at diagnosis <1 10 1 10.0 3 2 66.7 0 0.0 1 33.3 0 0.0 0 0.0

1-4 83 9 10.8 17 10 58.8 0 0.0 3 17.6 3 17.6 1 5.9

5-9 356 68 19.1 140 86 61.4 0 0.0 28 20.0 13 9.3 13 9.3

10-14 805 309 38.4 694 451 65.0 8 1.2 106 15.3 94 13.5 35 5.0

15-20 763 361 47.3 790 532 67.3 6 0.8 129 16.3 97 12.3 26 3.3

Treatment Surgery only 116 65 56.0 150 104 69.3 1 0.7 24 16.0 16 10.7 5 3.3

Chemotherapy, no radiation 1127 458 40.6 1011 666 65.9 7 0.7 160 15.8 135 13.4 43 4.3

Radiation, no chemotherapy 15 8 53.3 16 11 68.8 1 6.3 3 18.8 1 6.3 0 0.0

Chemotherapy and radiation 583 150 25.7 319 199 62.4 4 1.3 54 16.9 45 14.1 17 5.3

Unknown 176 67 38.1 148 101 68.2 1 0.7 26 17.6 10 6.8 10 6.8

Males All cases 1044 261 25.0 560 375 67.0 3 0.5 102 18.2 59 10.5 21 3.8

Age at baseline <18 48 . . . . . . . . . . . . .

18-19 36 . . . . . . . . . . . . .

20-24 189 13 6.9 20 12 60.0 0 0.0 4 20.0 1 5.0 3 15.0

25-29 293 54 18.4 92 58 63.0 1 1.1 17 18.5 9 9.8 7 7.6

30-34 271 95 35.1 202 137 67.8 1 0.5 29 14.4 29 14.4 6 3.0

35+ 207 99 47.8 246 168 68.3 1 0.4 52 21.1 20 8.1 5 2.0

Years since diagnosis 5-9 132 5 3.8 6 2 33.3 0 0.0 0 0.0 1 16.7 3 50.0

10-14 346 67 19.4 117 79 67.5 1 0.9 17 14.5 14 12.0 6 5.1

15-19 333 96 28.8 207 142 68.6 2 1.0 35 16.9 22 10.6 6 2.9

20+ 233 93 39.9 230 152 66.1 0 0.0 50 21.7 22 9.6 6 2.6

Age at diagnosis <1 4 . . . . . . . . . . . . .

1-4 43 4 9.3 8 4 50.0 0 0.0 3 37.5 0 0.0 1 12.5

5-9 185 15 8.1 29 23 79.3 0 0.0 4 13.8 2 6.9 0 0.0

10-14 385 86 22.3 189 118 62.4 1 0.5 39 20.6 24 12.7 7 3.7

15-20 427 156 36.5 334 230 68.9 2 0.6 56 16.8 33 9.9 13 3.9

Treatment Surgery only 49 18 36.7 39 25 64.1 0 0.0 7 17.9 6 15.4 1 2.6

Chemotherapy, no radiation 578 161 27.9 354 238 67.2 2 0.6 68 19.2 32 9.0 14 4.0

Radiation, no chemotherapy 7 3 42.9 6 3 50.0 0 0.0 2 33.3 1 16.7 0 0.0

Chemotherapy and radiation 299 44 14.7 94 62 66.0 1 1.1 14 14.9 14 14.9 3 3.2

Unknown 111 35 31.5 67 47 70.1 0 0.0 11 16.4 6 9.0 3 4.5

Females All cases 973 487 50.1 1084 706 65.1 11 1.0 165 15.2 148 13.7 54 5.0

Age at baseline <18 48 2 4.2 3 1 33.3 0 0.0 0 0.0 2 66.7 0 0.0

Page 26: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: All bone

Pregnancies in female survivors or female partners of male survivors

26

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

18-19 36 2 5.6 3 1 33.3 0 0.0 1 33.3 0 0.0 1 33.3

20-24 194 55 28.4 98 54 55.1 3 3.1 14 14.3 18 18.4 9 9.2

25-29 259 123 47.5 230 151 65.7 1 0.4 30 13.0 29 12.6 19 8.3

30-34 267 170 63.7 421 274 65.1 4 1.0 70 16.6 52 12.4 21 5.0

35+ 169 135 79.9 329 225 68.4 3 0.9 50 15.2 47 14.3 4 1.2

Years since diagnosis 5-9 109 19 17.4 29 19 65.5 0 0.0 3 10.3 5 17.2 2 6.9

10-14 330 126 38.2 249 152 61.0 5 2.0 38 15.3 40 16.1 14 5.6

15-19 308 177 57.5 400 259 64.8 4 1.0 57 14.3 51 12.8 29 7.3

20+ 226 165 73.0 406 276 68.0 2 0.5 67 16.5 52 12.8 9 2.2

Age at diagnosis <1 6 1 16.7 3 2 66.7 0 0.0 1 33.3 0 0.0 0 0.0

1-4 40 5 12.5 9 6 66.7 0 0.0 0 0.0 3 33.3 0 0.0

5-9 171 53 31.0 111 63 56.8 0 0.0 24 21.6 11 9.9 13 11.7

10-14 420 223 53.1 505 333 65.9 7 1.4 67 13.3 70 13.9 28 5.5

15-20 336 205 61.0 456 302 66.2 4 0.9 73 16.0 64 14.0 13 2.9

Treatment Surgery only 67 47 70.1 111 79 71.2 1 0.9 17 15.3 10 9.0 4 3.6

Chemotherapy, no radiation 549 297 54.1 657 428 65.1 5 0.8 92 14.0 103 15.7 29 4.4

Radiation, no chemotherapy 8 5 62.5 10 8 80.0 1 10.0 1 10.0 0 0.0 0 0.0

Chemotherapy and radiation 284 106 37.3 225 137 60.9 3 1.3 40 17.8 31 13.8 14 6.2

Unknown 65 32 49.2 81 54 66.7 1 1.2 15 18.5 4 4.9 7 8.6

Page 27: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Ewings 27

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 714 178 24.9 395 244 61.8 4 1.0 72 18.2 45 11.4 30 7.6

Age at baseline <18 61 1 1.6 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

18-19 36 1 2.8 2 1 50.0 0 0.0 1 50.0 0 0.0 0 0.0

20-24 168 21 12.5 43 19 44.2 3 7.0 7 16.3 4 9.3 10 23.3

25-29 199 45 22.6 73 46 63.0 0 0.0 15 20.5 7 9.6 5 6.8

30-34 155 58 37.4 144 82 56.9 1 0.7 25 17.4 23 16.0 13 9.0

35+ 95 52 54.7 132 96 72.7 0 0.0 24 18.2 10 7.6 2 1.5

Years since diagnosis 5-9 103 3 2.9 3 1 33.3 0 0.0 1 33.3 0 0.0 1 33.3

10-14 245 46 18.8 84 46 54.8 4 4.8 15 17.9 11 13.1 8 9.5

15-19 213 59 27.7 130 87 66.9 0 0.0 16 12.3 12 9.2 15 11.5

20+ 153 70 45.8 178 110 61.8 0 0.0 40 22.5 22 12.4 6 3.4

Age at diagnosis <1 5 . . . . . . . . . . . . .

1-4 52 5 9.6 11 5 45.5 0 0.0 3 27.3 2 18.2 1 9.1

5-9 181 29 16.0 59 31 52.5 0 0.0 16 27.1 4 6.8 8 13.6

10-14 267 65 24.3 155 84 54.2 3 1.9 31 20.0 22 14.2 15 9.7

15-20 209 79 37.8 170 124 72.9 1 0.6 22 12.9 17 10.0 6 3.5

Treatment Surgery only 1 1 100.0 1 0 0.0 0 0.0 1 100.0 0 0.0 0 0.0

Chemotherapy, no radiation 199 52 26.1 117 77 65.8 0 0.0 22 18.8 11 9.4 7 6.0

Radiation, no chemotherapy 2 1 50.0 2 2 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy and radiation 457 112 24.5 248 150 60.5 4 1.6 46 18.5 33 13.3 15 6.0

Unknown 55 12 21.8 27 15 55.6 0 0.0 3 11.1 1 3.7 8 29.6

Males All cases 371 51 13.7 111 67 60.4 1 0.9 22 19.8 13 11.7 8 7.2

Age at baseline <18 27 . . . . . . . . . . . . .

18-19 20 . . . . . . . . . . . . .

20-24 85 3 3.5 4 1 25.0 0 0.0 2 50.0 0 0.0 1 25.0

25-29 102 9 8.8 19 10 52.6 0 0.0 6 31.6 0 0.0 3 15.8

30-34 85 19 22.4 38 20 52.6 1 2.6 3 7.9 11 28.9 3 7.9

35+ 52 20 38.5 50 36 72.0 0 0.0 11 22.0 2 4.0 1 2.0

Years since diagnosis 5-9 55 1 1.8 1 1 100.0 0 0.0 0 0.0 0 0.0 0 0.0

10-14 119 15 12.6 26 15 57.7 1 3.8 4 15.4 2 7.7 4 15.4

15-19 117 13 11.1 26 18 69.2 0 0.0 5 19.2 2 7.7 1 3.8

20+ 80 22 27.5 58 33 56.9 0 0.0 13 22.4 9 15.5 3 5.2

Age at diagnosis <1 2 . . . . . . . . . . . . .

1-4 27 2 7.4 5 1 20.0 0 0.0 3 60.0 0 0.0 1 20.0

5-9 90 3 3.3 6 4 66.7 0 0.0 1 16.7 1 16.7 0 0.0

10-14 141 15 10.6 33 14 42.4 0 0.0 10 30.3 6 18.2 3 9.1

15-20 111 31 27.9 67 48 71.6 1 1.5 8 11.9 6 9.0 4 6.0

Treatment Chemotherapy, no radiation 104 12 11.5 33 17 51.5 0 0.0 10 30.3 2 6.1 4 12.1

Radiation, no chemotherapy 1 1 100.0 2 2 100.0 0 0.0 0 0.0 0 0.0 0 0.0

Chemotherapy and radiation 233 35 15.0 73 47 64.4 1 1.4 12 16.4 11 15.1 2 2.7

Unknown 33 3 9.1 3 1 33.3 0 0.0 0 0.0 0 0.0 2 66.7

Females All cases 343 127 37.0 284 177 62.3 3 1.1 50 17.6 32 11.3 22 7.7

Age at baseline <18 34 1 2.9 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

18-19 16 1 6.3 2 1 50.0 0 0.0 1 50.0 0 0.0 0 0.0

Page 28: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Ewings 28

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

20-24 83 18 21.7 39 18 46.2 3 7.7 5 12.8 4 10.3 9 23.1

25-29 97 36 37.1 54 36 66.7 0 0.0 9 16.7 7 13.0 2 3.7

30-34 70 39 55.7 106 62 58.5 0 0.0 22 20.8 12 11.3 10 9.4

35+ 43 32 74.4 82 60 73.2 0 0.0 13 15.9 8 9.8 1 1.2

Years since diagnosis 5-9 48 2 4.2 2 0 0.0 0 0.0 1 50.0 0 0.0 1 50.0

10-14 126 31 24.6 58 31 53.4 3 5.2 11 19.0 9 15.5 4 6.9

15-19 96 46 47.9 104 69 66.3 0 0.0 11 10.6 10 9.6 14 13.5

20+ 73 48 65.8 120 77 64.2 0 0.0 27 22.5 13 10.8 3 2.5

Age at diagnosis <1 3 . . . . . . . . . . . . .

1-4 25 3 12.0 6 4 66.7 0 0.0 0 0.0 2 33.3 0 0.0

5-9 91 26 28.6 53 27 50.9 0 0.0 15 28.3 3 5.7 8 15.1

10-14 126 50 39.7 122 70 57.4 3 2.5 21 17.2 16 13.1 12 9.8

15-20 98 48 49.0 103 76 73.8 0 0.0 14 13.6 11 10.7 2 1.9

Treatment Surgery only 1 1 100.0 1 0 0.0 0 0.0 1 100.0 0 0.0 0 0.0

Chemotherapy, no radiation 95 40 42.1 84 60 71.4 0 0.0 12 14.3 9 10.7 3 3.6

Radiation, no chemotherapy 1 . . . . . . . . . . . . .

Chemotherapy and radiation 224 77 34.4 175 103 58.9 3 1.7 34 19.4 22 12.6 13 7.4

Unknown 22 9 40.9 24 14 58.3 0 0.0 3 12.5 1 4.2 6 25.0

Page 29: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Osteosarcoma 29

Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

Both sexes All cases 1205 539 44.7 1182 794 67.2 10 0.8 183 15.5 151 12.8 44 3.7

Age at baseline <18 29 1 3.4 2 1 50.0 0 0.0 0 0.0 1 50.0 0 0.0

18-19 30 1 3.3 1 0 0.0 0 0.0 0 0.0 0 0.0 1 100.0

20-24 198 44 22.2 67 43 64.2 0 0.0 9 13.4 13 19.4 2 3.0

25-29 333 128 38.4 240 156 65.0 2 0.8 30 12.5 31 12.9 21 8.8

30-34 356 198 55.6 460 317 68.9 4 0.9 68 14.8 57 12.4 14 3.0

35+ 259 167 64.5 412 277 67.2 4 1.0 76 18.4 49 11.9 6 1.5

Years since diagnosis 5-9 131 20 15.3 31 20 64.5 0 0.0 2 6.5 5 16.1 4 12.9

10-14 394 140 35.5 267 174 65.2 2 0.7 37 13.9 42 15.7 12 4.5

15-19 401 206 51.4 459 302 65.8 6 1.3 71 15.5 60 13.1 20 4.4

20+ 279 173 62.0 425 298 70.1 2 0.5 73 17.2 44 10.4 8 1.9

Age at diagnosis 1-4 24 4 16.7 6 5 83.3 0 0.0 0 0.0 1 16.7 0 0.0

5-9 159 38 23.9 78 53 67.9 0 0.0 11 14.1 9 11.5 5 6.4

10-14 509 235 46.2 515 353 68.5 5 1.0 70 13.6 67 13.0 20 3.9

15-20 513 262 51.1 583 383 65.7 5 0.9 102 17.5 74 12.7 19 3.3

Treatment Surgery only 83 48 57.8 118 81 68.6 1 0.8 19 16.1 12 10.2 5 4.2

Chemotherapy, no radiation 907 401 44.2 880 583 66.3 7 0.8 134 15.2 121 13.8 35 4.0

Radiation, no chemotherapy 9 6 66.7 13 8 61.5 1 7.7 3 23.1 1 7.7 0 0.0

Chemotherapy and radiation 91 31 34.1 55 39 70.9 0 0.0 6 10.9 8 14.5 2 3.6

Unknown 115 53 46.1 116 83 71.6 1 0.9 21 18.1 9 7.8 2 1.7

Males All cases 624 199 31.9 425 293 68.9 2 0.5 74 17.4 43 10.1 13 3.1

Age at baseline <18 20 . . . . . . . . . . . . .

18-19 12 . . . . . . . . . . . . .

20-24 95 10 10.5 16 11 68.8 0 0.0 2 12.5 1 6.3 2 12.5

25-29 180 43 23.9 69 45 65.2 1 1.4 10 14.5 9 13.0 4 5.8

30-34 172 72 41.9 155 112 72.3 0 0.0 22 14.2 18 11.6 3 1.9

35+ 145 74 51.0 185 125 67.6 1 0.5 40 21.6 15 8.1 4 2.2

Years since diagnosis 5-9 74 4 5.4 5 1 20.0 0 0.0 0 0.0 1 20.0 3 60.0

10-14 208 49 23.6 84 59 70.2 0 0.0 11 13.1 12 14.3 2 2.4

15-19 203 80 39.4 176 121 68.8 2 1.1 28 15.9 20 11.4 5 2.8

20+ 139 66 47.5 160 112 70.0 0 0.0 35 21.9 10 6.3 3 1.9

Age at diagnosis 1-4 13 2 15.4 3 3 100.0 0 0.0 0 0.0 0 0.0 0 0.0

5-9 82 11 13.4 20 17 85.0 0 0.0 2 10.0 1 5.0 0 0.0

10-14 235 70 29.8 154 103 66.9 1 0.6 28 18.2 18 11.7 4 2.6

15-20 294 116 39.5 248 170 68.5 1 0.4 44 17.7 24 9.7 9 3.6

Treatment Surgery only 31 12 38.7 26 18 69.2 0 0.0 4 15.4 3 11.5 1 3.8

Chemotherapy, no radiation 464 148 31.9 320 220 68.8 2 0.6 58 18.1 30 9.4 10 3.1

Radiation, no chemotherapy 5 2 40.0 4 1 25.0 0 0.0 2 50.0 1 25.0 0 0.0

Chemotherapy and radiation 50 7 14.0 16 11 68.8 0 0.0 1 6.3 3 18.8 1 6.3

Unknown 74 30 40.5 59 43 72.9 0 0.0 9 15.3 6 10.2 1 1.7

Females All cases 581 340 58.5 757 501 66.2 8 1.1 109 14.4 108 14.3 31 4.1

Age at baseline <18 9 1 11.1 2 1 50.0 0 0.0 0 0.0 1 50.0 0 0.0

18-19 18 1 5.6 1 0 0.0 0 0.0 0 0.0 0 0.0 1 100.0

20-24 103 34 33.0 51 32 62.7 0 0.0 7 13.7 12 23.5 0 0.0

Page 30: Pregnancy Outcomes: All cancers 1 Pregnancies in …...Pregnancy Outcomes: All cancers Pregnancies in female survivors or female partners of male survivors 2 CCSS data from Dec2010

CCSS data from Dec2010 and March 2015 data freeze

Based on items in M11/N8 1 Indicates at least one pregnancy for the survivor. Denominator for percentage is all cases. 2 Reported outcomes for all pregnancies, including multiple pregnancies per survivor. Denominator for percentages is all pregnancies 3 Unknown includes pregnancies with outcome unknown or currently pregnant

Pregnancy Outcomes: Osteosarcoma 30Pregnancies in female survivors or female partners of male survivors

Pregnancy Outcome 2

Any pregnancy1

Live Births Stillbirths Miscarriages Abortions Unknown3

All cases N %

Total # pregnancies N % N % N % N % N %

25-29 153 85 55.6 171 111 64.9 1 0.6 20 11.7 22 12.9 17 9.9

30-34 184 126 68.5 305 205 67.2 4 1.3 46 15.1 39 12.8 11 3.6

35+ 114 93 81.6 227 152 67.0 3 1.3 36 15.9 34 15.0 2 0.9

Years since diagnosis 5-9 57 16 28.1 26 19 73.1 0 0.0 2 7.7 4 15.4 1 3.8

10-14 186 91 48.9 183 115 62.8 2 1.1 26 14.2 30 16.4 10 5.5

15-19 198 126 63.6 283 181 64.0 4 1.4 43 15.2 40 14.1 15 5.3

20+ 140 107 76.4 265 186 70.2 2 0.8 38 14.3 34 12.8 5 1.9

Age at diagnosis 1-4 11 2 18.2 3 2 66.7 0 0.0 0 0.0 1 33.3 0 0.0

5-9 77 27 35.1 58 36 62.1 0 0.0 9 15.5 8 13.8 5 8.6

10-14 274 165 60.2 361 250 69.3 4 1.1 42 11.6 49 13.6 16 4.4

15-20 219 146 66.7 335 213 63.6 4 1.2 58 17.3 50 14.9 10 3.0

Treatment Surgery only 52 36 69.2 92 63 68.5 1 1.1 15 16.3 9 9.8 4 4.3

Chemotherapy, no radiation 443 253 57.1 560 363 64.8 5 0.9 76 13.6 91 16.3 25 4.5

Radiation, no chemotherapy 4 4 100.0 9 7 77.8 1 11.1 1 11.1 0 0.0 0 0.0

Chemotherapy and radiation 41 24 58.5 39 28 71.8 0 0.0 5 12.8 5 12.8 1 2.6

Unknown 41 23 56.1 57 40 70.2 1 1.8 12 21.1 3 5.3 1 1.8