ppr capabilities
TRANSCRIPT
Corporate Capabilities
1580 McLaughlin Run Road
Pittsburgh, PA 15241
412-257-4461www.pprresearch.com
Quality Research Today for a Better Tomorrow
Primary Physicians Research is an established clinical research provider
We offer:
10 independent, community-based research sites
2 multi-specialty sites
Over 25 years of experience
Over 700 trials.
Dedicated QA/QC department, assuring quality
conduct as well as patient safety
70+ physician network of investigators
A rapidly growing database of over 300,000
patients
Nearly 33,000 study participants (2005-2011)
A strong history of high-quality performance
Strong Enrollment
Reliability
Clean Data
Quick Turnaround
History of strong performance
Phase I-IV and OTC clinical trial capabilities
Ability to accommodate specialist trials
Able to handle large, quick enrollments, due to seasonal issues
Consistent history of achieving and exceeding contracted enrollment
Overenrolled in over 30% of studies from February 2006 – February 2011
Primary Investigators, Sub Investigators, and highly trained staff at each site to
oversee and execute the study protocol
Fully equipped neighborhood offices that offer convenience and familiarity to study
subjects.
A proven track record in pediatric and adult research.
PPR’s Facility PPR’s dedicated research facility is located within the Jefferson Regional Hospital
State of the art on-site
lab capabilities Separate monitor
room with high -speed
Internet, Fax, Phone.
On site PI
Comfortable waiting room
Studies Conducted 300
Total Enrollment Since 2002 30,800
Total Completed 29,974
Studies conducted between January 2002 - February 2011
Patient completion %
Patient drop-out %
Note: The above is all-inclusive of studies taken on by PPR during the period - without regard to size, type, ease/difficulty or
continuance/discontinuance.
2.5-Year Average Study Yield
Jan 2008- February 2011
3.3%
96.6%
97% of patients completed study protocols
Note: The above represents PPR’s mix of business by number of studies across its 7 largest customers over the last 10 years
Merck24%
Abbott4%
GSK29%
Sanofi15%
Lilly1%
Pfizer/Wyeth14%
Novartis13%
7 Largest Sponsors – 10 Year Snapshot
PPR has a strong history with numerous pharmaceutical companies:
Our quality assurance goal is to achieve, sustain, and improve quality in all
aspects of research within the clinical site arena.
PPR’s QA Department has been organized to drive a data quality focus
throughout the organization. This is achieved by:
Training staff on an ongoing basis
Monthly meetings to identify and correct potential adverse trends in
data quality
A Quality Assurance Liaison visits sites monthly to correct identified
problems and trends and works with PIs to ensure adherence to protocol
and GCP’s
In-house audits are performed and quality indicators are reviewed on a
per trial basis
Identifying and implementing best practices for delivering quality data
Quality Assurance
Clinical Conductor manages the large amounts of data involved with the
operation of a clinical trial.
Some of the benefits of using a CTMS include:
Improves recruitment efficiency
Better management of budgets and financials
Tracks advertising responses
Full oversight of multiple trials at multiple sites
Strong Clinical Trial Management Information System
Recruitment and marketing: A top priority
PPR has a marketing and site recruitment team who is solely dedicated to patient
enrollment
Marketing techniques play a pivotal role in how targeted patients become aware of
clinical trials
In-house marketing staff creates advertising and marketing tools that are used by
sub-investigators and site personnel to increase enrollment
Staff adheres to ICH guidelines in obtaining IRB approvals for marketing tools
PPR utilizes online marketing resources and social media tools for patient
recruitment
PPR maintains an active
online presence through it’s
website, social media
networks, and craigslist
Recent Accomplishments:
Used Craigslist.com to
recruit nearly 75% of goal
patients in an osteoarthritis
study with a contracted goal
of 20 patients
Used Craigslist.com to enroll
over 100% of the set 40
patient goal in a Women’s
Health study
Online marketing and social media tools
Trial Experience
Diptherial/Pretussis/Tetanus
DTaP
Tetanus/Diphtheria
Varicella
eIPV
Rotavirus
Influenza (intranasal
Influenza (injection)
Influenza (cellular)
Meningococcal A,C,Y,W-135
Meningococcal B
Lyme Disease
Parainfluenza
Pneumococcal
DTaP/IPV/Hep B (Pediarix)
Haemophilus influenza type B
Hepatitis A
Hepatitis B
Human Papillomavirus
Plague
Respiratory Syncytial Virus (RSV)
Anthrax
Diphtherial/Pertussis/Polio/Tetanus
Meningococcal A,C,W,Y
MMRV
Herpes Simplex Virus
Hepatitis AB
PIV3RSV
Dtap/Hib/IPV (Pentacel)
PPR has conducted numerous vaccine trials including:
Asthma
Osteoporosis
Osteoarthritis
Obesity
Herpes simplex
Antivirals
Diabetes
Strep throat
Antipyretics
Lipids
Influenza
Pharmacokinetics
Migraine
Atrial Fibrillation
Topical Otologicals
Topical Ophthalmologics
Contraceptives
Arthritis
Back pain
Pharyngitis
Acute bronchitis
Chronic bronchitis
Sinusitis
Pneumonia
Otitis media
Bacterial vaginosis
Infant formula
Hypoactive Sexual Desire
Disorder
PPR has conducted numerous therapeutic and nutritional trials:
Our Clients
Note: The above is meant to show PPR’s substantial client base developed over time. It should be noted that some of the above listed clients have
since merged, been acquired or otherwise joined with competitors.
Aventis
Abbott
Advancis
Alcon
Allergan
Almirall
Prodesfarma
Aviron
BioCryst
Bristol Myers
Squibb
Cephalon
Chiron
Dimethaid
Dynavax
Dynport
Genentech
Gilead Sciences
GlaxoSmithKline
GlaxoWelcome
Inspire
Iomai
Johnson & Johnson
KV Pharma
Eli Lilly
Mead Johnson &
Company
MedImmune
Merck
NABI Pharmaceutical
Novartis
Ortho-McNeil
Osiris Therapeutics
Pfizer
Pharmacia
Protein Sciences
Roche
RWJ
Sanofi
Sanofi Aventis
Sanofi Pasteur
Sepracor
Schering-Plough
Shire
Takeda
VaxGen
ViroPharma
Wyeth
PPR has a strong history with numerous pharmaceutical companies:
Advanced Biologics
Covance
I3 research
Icon
MDS
OmnicareCR
Parexel
Pharmanet
PPD
Quintiles
United Biosource Corp
PPR is proud of its working relationships with government agencies
The National Institutes of Health
Working on protocols that have been initiated by the NIH
The Department of Defense
Worked on vaccines to protect military men and women over the last 5 years
The Division of Microbiology and Infectious Diseases (DMID)
Approved by the DMID to work on vaccine trials in collaboration with NIH and VTEU sites
Created QA/QC program that has been approved by the DMID
Subcontractor for the Vaccine and Treatment Evaluation Units (VTEU) program
Partner with the University of Saint Louis to work with them in numerous vaccine trials
PPR has strong relationships with CROs and others:
PPR provides:
Experienced leadership oversees the key functions supporting trial success
Clinical staff receives extensive training and is dedicated solely to conducting
research
Consistent and strong enrollment
Quality data
A team dedicated to delighting our clients!
PRESIDENT & CEO
Paul E. Curley
Phone :412-257-4461 ext 212
Cell: 610-745-9155
EXECUTIVE DIRECTOR, COMMERCIAL OPERATIONS
Carol L. Miller, LPN, CCRC
Phone :412-257-4461 ext 127
Cell: 724-518-9531
BUSINESS DEVELOPMENT
Corry Knuth
Phone :412-257-4461 ext 126
Cell: 724-570-4798
Our clinical research team:
Primary Physicians Research welcomes the opportunity to speak with you to provide more
information about our experience conducting clinical trials or for the opportunity to conduct a
clinical trial for you. Please contact us: