postoperative pain assessment and management
DESCRIPTION
pain, postoperative, opioids side effectsTRANSCRIPT
Acute postoperative Pain Assessment and
Management
PRESENTED BY
Dr. MAHMOUD A. KAFY
MD Anesthesia & ICU
MINISTRY OF HEALTHFUJAIRAH HOSPITAL
Objectives• Be able to provide a definition for pain
• Have an understanding of pain assessment and pain assessment tools
• Have a knowledge of analgesic drugs and side effects of drugs
• Have an understanding of routes of drug administration
INTRODUCTION
“Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage.”IASP (1979)
Definition of pain
• Implies emotional component.• Pain can exist without tissue
damage.
PATHOPHYSIOLOGY OF PAIN
• Involves four physiological processes:
- Transduction
- Transmission
- Modulation
- Perception
Pain Language
• Acute pain: lasts less than 6 months, subsides once the healing process is accomplished.
• Chronic pain: involves complex processes and pathology. Usually involves altered anatomy and neural pathways. It is constant and prolonged, lasting longer than 6 months, and sometimes, for life.
Why Treat Pain?
• Basic human right!
• ↓ pain and suffering
• ↓ complications of unreleived pain
• ↓ chronic pain development
• ↑ patient satisfaction
• ↑ speed of recovery → ↓ length of stay → ↓ cost
• ↑ productivity and quality of life
Barriers to Effective Pain Management
● Multidisciplinary factors
- lack of knowledge
- failure to recognize multi - faceted nature of pain
- poor interpretation of information
● Patient factors
- unwillingness to report pain
- non compliance with treatment
- lack of knowledge / information
COMPLICATIONS OF
UNRELIEVED PAIN
Pain may be undertreated
Physicians may have concern that pain medications will:
- worsen hemodynamic instability - produce harmful or long-lasting metabolites in the
setting of multiple organ dysfunction - Impair the ability to examine a patient’s mental status.
However, these concerns must be balanced against harmful effects of undertreatment of pain.
Adverse effects of unrelieved PainAdverse effects of unrelieved PainCardiovascularCardiovascular Heart Rate
Blood PressureIncreased
myocardial o2
demandHypercoagulation
Unstable anginaMyocardial infarctionDVTPE
RespiratoryRespiratory Lung VolumesDecreased coughRetension of secretion
AtelectasisPneumoniaHypoxemia
GIGI Gastric Emptying Bowel Motility
ConstipationAnorexiaIleus
National Pharmaceutical Council (2001). Macintyre & Schug (2007).Cohen et al (2004)
Adverse effects of unrelieved PainAdverse effects of unrelieved PainNeuroendocrinNeuroendocrinee
Altered release of multiple hormones
HyperglycemiaWt loss/ muscle wastingImpaired wound healingImpaired immune function
MSKMSK Muscle spasmImpaired muscle mobility & function
ImmobilityWeaknessFatigue
PsychologicalPsychological AnxietyFear
Sleep deprivationPost traumatic stress disorder
PAIN PATHWAY
Pain Pathway – Pain Management
Tricyclic AntidepressantsOpioidsSSRI
Anticonvulsants
PAIN ASSESSMENT
Pain Assessment
“One of the most important functions of the nurse is to alleviate the suffering of people who are experiencing pain”
Schofield P(1995)
Why we assess pain ?• To establish degree and nature of pain
• To ensure patient comfort
• To evaluate effectiveness of analgesia
• To help alleviate anxiety
• To decide on type of analgesia
• To aid recovery and prevent complications
When should pain be measured
• Usually asked when pt. are resting .
• Better indicator is assessment of pain during coughing , deep breathing or movement .
• Regular reassessment .
How to assess pain
• Communication with patient is essential
• Observe for changes in physiological signs
• Consider pain as 5th vital sign
• Use a pain scoring system
pain Assessment in Critical Care
In patients who are unable to self-report and in whom motor function is intact and behaviors are observable.The Behavioral Pain Scale (BPS) and the Critical-Care Pain Observation Tool (CPOT) are the most valid and reliable behavioral pain scales for monitoring pain in• Medical ICU• Postoperative, • Trauma (except for brain injury)
In patients who are unable to self-report and in whom motor function is intact and behaviors are observable.The Behavioral Pain Scale (BPS) and the Critical-Care Pain Observation Tool (CPOT) are the most valid and reliable behavioral pain scales for monitoring pain in• Medical ICU• Postoperative, • Trauma (except for brain injury)
Identifying and Treating PainIdentifying and Treating Pain
Patients who can self reportNumerical scale
Guideline do not suggest that vital signs be used alone for pain assessment in adult ICU patients. Guideline suggest that vital signs may be used as a cue to begin further assessment of pain in these patients,
Assess pain ≥ 4 times per shift & as needed
Pain is a more terrible lord of mankind than even death itself”
DO:301DO:301
Pain in the ICU
*CPOT range = 0 – 8, CPOT > 3 is significant
Critical Care Pain Observation Tool* (CPOT)
post operative painmanagement
Management of acute painAnalgesic drugs are used to treat acute pain,
the choice of drug dependent on the intensity of pain being experienced.
Analgesic Ladder
What is the “Best Way” to manage acute pain?
• FIRST , DO NO HARMTherefore , the “best way” is a BALANCE
Patient Safety
Effective AnalgesicModalities
How do we do it?• Multimodal analgesia : Several analgesics with
different mechanisms of action , each working at different sites in the nervous system
• Acetaminophen
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Opioids
• NMDA Antagonists
• Local anaesthetics
• Non-pharmacologic methods
Methods of administration• Epidural Analgesia• Patient Controlled Analgesia [ intra - venous ]• Intra Muscular Injection• Sub Cutaneous• Oral• Rectal [ suppositories ]• Transdermal• Inhalation [ gas ]• Regional Nerve Blocks e.g. Paravertebral, Brachial Plexus block.• Wound Infiltration
Opioid
Opioid is a blanket term used for any drug which binds to the opioid receptors in the CNS.
Opioids for acute pain (ARI)• Morphine• Diamorphine• Fentanyl • Oxycodone• Tramadol• MST continus• Hydormorphone• Codeine• Dihydrocodeine
Adverse effects of opioids• Respiratory Depression
• Sedation
• Nausea and Vomiting
• Pruritus
• Urinary retention
• Hallucinations
PARACETAMOL
Mechanism of action: ? Selective inhibition of
prostaglandin synthesis in CNS
Analgesic and antipyretic
Oral , rectal and intravenous prep
Useful adjunct
NSAIDS• Work at site of tissue injury to prevent the formation
of the nociceptive mediators Prostaglandins.• Can decrease opioid use ~30% therefore decreasing
opioid-related side effects• NSAIDs should be the first-line drug for treatment
of mild to moderate pain & should be used in combination with opioids for more severe pain .
• Adv. : no sedation , resp. depression , N&V.– Side effects : GI upset , gastric ulcers , decrease
renal medullary blood flow , reversible inhibition of platelet function
NSAIDS• Newer NSAIDS selectively (primarily) inhibit
cyclooxygenase-2 (COX-2) which is induced by surgical trauma with minimal effect on COX-1 which is responsible for GI and platelet side effects
• Equivalent analgesic efficacy with non-selective COX-inhibitors
• No effects on platelets!
• Much reduced incidence of upper GI S/E compared to non-selective
• Duration of action about 24 hr.
NMDA Receptor Antagonists • Ketamine : - Ketamine 0.15 - 0.3 mg/kg IV with induction of
general anesthesia has pre-emptive analgesic effects - less pain and less opioid use post-op
- Low dose (0.25-0.5 mg/kg) IV bolus followed by infusion of 2-4 µg/kg/min , can provide significant analgesia.
- Ketamine as co-analgesic , combined 1:1 with morphine IV PCA . Better analgesia , less S/E
Dexmedetomidine :- Highly selective - Highly selective αα22 agonist. agonist.
- Does not depress the respiratory drive.- Does not depress the respiratory drive.
- Causes- Analgesia dose-dependent , sedation - Causes- Analgesia dose-dependent , sedation (“(“Cooperative sedationCooperative sedation”), anxiolysis.”), anxiolysis.
- Reduction in Sympathetic tone.- Reduction in Sympathetic tone.- Useful adjunct to both opioid & non-opioid analgesicUseful adjunct to both opioid & non-opioid analgesic.- Side effects : Bradycardia , Hypotension
- Dose : Loading dose – 1 µg/kg i.v. over 10 min , followed by infusion of 0.2-0.7 µg/kg/hr.
- Metabolised by liver & excreted in urine.
NON PHARMACOLOGICAL METHODS
• CRYOTHERAPY
• TENS
• ACUPUNCTURE
THANK YOU