positions available

Cell, vol. 50. NO. 5, August 28, 1987

Positions Available

Cell Classified Information Cell publishes classified advertisements for positions available, and for announcements of meetings, symposia, and courses. Rates are $175 for a quarter page, $325 for a half page, and $695 for a full page. We will accept either camera-ready material or copy for typesetting. Deadlines for the next available issues are as follows (all material due close of business on due date):

*Sept. II, 1987 issue: copy due Aug. 6, 1987 *Sept. 25, 1987 issue: copy due Aug. 21, 1987 *Oct. 9, 1987 issue: copy due Sept. 3, 1987 *Oct. 23,1987 issue: copy due Sept. 18,1987 l NOV. 6,1987 issue: copy due Oct. I, 1987 l NOV. 20,1967 issue: copy due Oct. 15,1987 .Dec. 4,1987 issue: copy due Nov. 51987 *Dec. 24,1967 issue: copy due Nov. 12,1987

Advertisements should be sent to: Allison Kemmerer

Classified Ad Department Cell

50 Church Street Cambridge, MA 02138 (617-661-7059).

Research Associate Postdoctoral Fellow Massachusetts General Hospital

A research associate/postdoctoral position is available immediately to join multi-disciplinary group engaged in insulin growth factor action. Project involves purification and characterization of growth factor-stimulated P-tyr proteins. Strong background in monoclonal antibodies and experience with protein peptide purification is required. Protein micro- sequencing, oligonucleotide and peptide synthesis available via adjacent core laboratory. Send curriculum vitae and three letters of reference to:

Dr. Joseph Avruch Chief, Diabetes Unit Massachusetts General Hospital Boston, MA 02114 or call (617) 726-8909.

Research Associate Boston University School of Medicine

Postdoctoral position - a cellular/molecular biologist is sought to characterize and clone cDNA for proteins associated with a unique intracellular vesicle that reversibly moves to the cell surface in response to hormone/growth factors. This is one of several ongoing projects directed towards understanding the transmembrane signalling mechanism of receptor/tyrosine kinases (Insulin, IGF-I, EGF), and the pleiotropic consequences of such signalling.

Send a resume and the names of three references to:

Dr. Paul F. Pilch Department of Biochemistry Boston University School of Medicine 80 E. Concord Street Boston, MA 02118.

An Equal Opportunity Employer, M/F.

Cell, Vol. 50, No. 5. August 28, 1987

Postdoctoral Position Howard Hughes Medical Institute UCLA School of Medicine

A postdoctoral position is available immediately in a laboratory studying human molecular genetics. The principal research focus is the biology of mammalian sex chromosomes. Control of gene expression via X chromosome inactivation, as well as X and Y homology, pairing, and recombination are being studied along with the mechanisms of several inherited diseases. Extensive use is made of somatic cell genetics, molecular methods, and clinically derived chromosome rearrangements. A recent Ph.D. degree with experience in cloning and sequencing methods is required. Send curriculum vitae with the names of three references to: Larry J. Shapiro, M.D. Professor of Pediatrics and Biological Chemistry Howard Hughes Medical Institute UCLA School of Medicine Division of Medical Genetics 1000 West Carson Street Torrance, CA 90509.

Postdoctoral Positions University of California, San Francisco

Two postdoctoral positions are available for study of scrapie prion protein chemistry. Experience in carbohydrate structure determination, mass spectrometry analysis of protein modifications, membrane protein reconstitution, or structural and conformational analysis of proteins is highly preferred. NIH stipends range from $15,996 - $30,OOO/yr. according to experience. Candidates must be US citizens, or possess permanent residence visas. Send curriculum vitae and three letters of reference to:

Dr. Stanley Prusiner UCSF, San Francisco San Francisco, CA 94143-0518.

An Affirmative Action/Equal Opportunity Employer.

Postdoctoral Positions The Center for Applied Molecular Biology and Immunology SUNY at Buffalo

AIDS RESEARCH. The Center for Applied Molecular Biology and Immunology of the State University of New York at Buffalo is seeking highly qualified individuals to join an interdisciplinary research group studying the molecular biology and immunology of HIV. The projects presently underway include studies on (1) HIV envelope protein expression and biogenesis, (2) studies exploring the molecular interactions between EBV and HIV and (3) regulation of HIV gene expression. Experience in virology, recombinant DNA technology, cell culture or molecular immunology is required. Send curriculum vitae, and names of three references to: Dr. M.L Hammarskjoid and Dr. D. Rekosh Department of Microbiology 203 Sherman Hall SUNY at Buffalo Buffalo, NY 14214. An Afirmative Action/Equal Opportunity Employer.

Postdoctoral Research Associate Brown University

A postdoctoral position is available immediately involving work on oncogene and growth factor expression in normal and transformed liver cells and studies of cell lineages and stem cells in liver carcinogenesis. Experience with molecular biology techniques and/or tissue culture methodology is desirable. Please send curriculum vitae and names and addresses of two referees to:

Nelson Faust0 Department of Pathology and Laboratory Medicine Division of Biology and Medicine Brown University Providence, RI 02912.

Brown University is an Equal Opportunity/Affirmative Action Employer.

Cell, Vol. 50. No. 5, August 28. 1997

Postdoctoral/Research Associate Molecular Parasitology SUNY at Buffalo

A postdoctoral/research associate position is available immediately in a highly interactive group studying regulation of gene expression in the human blood fluke Schistosoma. This ongoing project involves identification and characterization of genes and gene products that play a role in immunity. cDNA and genomic clone banks and well-defined sera are available. Initial appointments are for two years with a competitive salary. Respond with curriculum vitae and names of three references with phone numbers to:

Drs. Phillp T. LoVerde or Davld M. Rekosh Department of Microbiology School of Medicine 203 Sherman Hall SUNY at Buffalo Buffalo, NY 14214.

An Affhmative Action/Equal Opportunity Employer.

STAFF POSITIONS

DEPARTMENT OF CELL ANDJ~o~~y?MENIAL

ROCHE INSTITUTE OF MOLECULAR BIOLOGY

A s part of a newly expanded program in developmental biology, applications are invited for sev- era1 positions equrvalent in rank to Assrstant,

Associate, and Full Professor. Candidates are sought who are applyin contemporary ex erimental approaches to basic

8. researc rn developmental rology. as it is broadly defmed. 1, ‘Institute staff enjoy total freedom and independence in therr choice and pursuit of research problems, as well as full funding of their research programs, includmg postdoctoral fellows, by Hoffmann-La Roche. The Institute IS located in a suburban setting only 10 miles west of New York City Send curriculum vitae, names of three references, and summary of research interests to: Or. Paul Wassarman, Chairman, Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Nstley, New Jersey 07llO. We are an equal opportunity employer.

4D Roche Institute of Molecular Biology Hollmann~la Roche Inc

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Postdoctoral Position Molecular Virology Public Health Research Institute

An NIH-funded postdoctoral position is available immediately to perform studies of structural and functional correlations of retroviral gene products by site-specific mutagenesis. Systems being studied include murine leukemia viruses, spleen focus-forming viruses, and HIV. A molecular genetic background is essential, with experience in gene cloning and in vitro mutagenesis preferred. Salary will be commensurate with experience. Send a curriculum vitae and three letters of recommendation to:

Dr. Abraham Pinter Department of Retroviral Biology Public Health Research Institute 455 First Avenue New York, NY 10016.

Cell, Vol. 50. No. 5, August 28, 1987

Postdoctoral Fellowship Duke University Medical Center

This research project involves the study of the toxin, w, in m. A major effort will be the generation of mutant yeast resistant to the toxin, as well as the molecular characterization of these mutations. A related project will involve in-vitro and in-vivo studies of the functional domains of ricin, both with regard to uptake and toxicity. The position is available immediately at $18,000- $21 ,OOO/year.

Contact: Dr. Arthur E. Frankel at (919-664-5060) or Dr. Stephen Johnston at (919-664-4123).

Head Department of Biological Sciences Purdue University

The Department of Biological Sciences, Purdue University, is seeking an established scholar with broad interests to serve as Head of the Department. The Department has about sixty faculty members and extensive teaching, research, and service responsibilities appropriate to a publicly supported university. We are looking for a person with a record of outstanding scientific achievement and commitment to higher education. Applications and nominations, including a curriculum vitae, bibliography, and names of three individuals familiar with the candidate’s qualifications, should be sent by October 15, 1967 to: Search Committee Convener Department of Biological Sciences Purdue University West Lafayette, Indiana 47907.

Purdue University is an Equal Opportunity/Affirmative Action Employer.

Wavne State University

Faculty Positions

Wayne State University

The Department of Molecular Biology and Genetics, with the support of the Molecular Biology Center at Wayne State University, invites applications for multiple tenure track faculty positions for Fall, 1988 or earlier hire dates at the level of ASSISTANT, ASSOCIATE, or FULL PROFESSOR, depending upon qualifications and experience. Generous start-up funds will be available. These positions are part of a major University-wide expansion in molecular biology. While emphasis is on health related research, candidates with demonstrated research excellence in any area of molecular biology or molecular genetics will be considered. Send applications (deadline: November 1, 1987), including curriculum vitae, the names of at least three references, and a statement of future research plans to:

Orlando J. Miller, M.D. Chairman

Department of Molecular Biology and Genetics

Wayne State University School of Medicine 540 East Canfield

Room 3216 Scott Hall Detroit, Ml 46201.

Wayne State University is an Equal Opportunity/Affhative Action Employer and actively seeks applications from women and minority groups.

cell, vol. so, NO. 5. August 28. 1987


Research Positions in

Molecular Biology


The Molecular Biology Center at Wayne State University invites applications for multiple research positions for Fall, 1988 or earlier hire dates at the level of assistant professor (research), associate professor (research), and professor (research), depending upon qualifications and experience. These positions carry generous start-up funds and are part of a major University-wide expansion in molecular biology. A primary goal of the Center is improvement in human health with a concern for biotechnology implementation. Four broad areas of research are emphasized: gene structure and function, organization of the human genome, synthesis and characterization of new macro- molecules (products), and protein structure and function. Candidates with demonstrated research excellence in any area of molecular biology or molecular genetics will be considered. Send application (deadline: November 15, 1987), including curriculum vitae, the names of at least three references, and a statement of future research plans to:

Orlando J. Miller, M.D. Director

Molecular Biology Center Wayne State University

540 East Canfield Room 3216 Scott Hall

Detroit, Ml 48201.

Wayne State University is an Equal OppoHuniiy/AfRmative Action Employw and a&e/y seeks applications from women and minority grvups.

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Research Assistant Professor of Pediatrics The University of Pennsylvania

An opening exists in the Division of Pediatric Hematology, University of Pennsylvania School of Medicine, for a Ph.D. with two or more years postdoctoral experience in cloning, sequence determination, and functional expression of cloned genes. Hands-on experience in oligonucleotide synthesis and isolation and DNA sequence determination is necessary. Candidate will be involved in development and management of protein and nucleic acid synthesis/microsequenoing facility and in collaborative studies of globin and megakaryocyte gene expression in humans. Applicant will be expected to obtain extramural funding within a reasonable period. Contact: Elias Schwartz, M.D. Dlrector, Division of Hematology The Children’s Hospital of Philadelphia 34th Street and Civic Center Boulevard Philadelphia, PA 19104. The University of Pennsylvania is an Equal Opportunity/Aftirmat Action Employer.

Cell, Vol. 50, No. 5, August 28, 1987

Molecular Parasitologist University of Cincinnati

The Department of Biological Sciences, University of Cincinnati, invites applications for an ASSISTANT PROFESSOR TENURE TRACK position in the area of MOLECULAR PARASITOLOGY, beginning September 1, 1988. The candidate must have completed a doctorate, with postdoctoral experience required. The successful candidate will be expected to develop an externally funded independent research program studying the molecular basis of the biology of parasites and/or host-parasite interactions, with animal systems preferred. In addition, the candidate will participate in graduate and undergraduate education. Applicants must submit a curriculum vitae, a one page statement of research goals, and have at least three letters of recommendation submitted to: Dr. Richard D. Karp, Molecular Parasitologist Search Committee, Department of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221. The deadline for applications is November 15, 1987. The University of Cincinnati is an Equal Opportuniiy/ Affirmative Action Employer.

Protein Biochemist and Molecular Biologist LSU Medical Center

The Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center in Shreveport, invites applications for two faculty positions at the associate or full professor level to share in the leadership of an expanding department. Outstanding candidates at the assistant professor level will also be considered. The successful applicants are expected to conduct a vigorous research program in the areas of protein biochemistry, molecular biology or molecular genetics. Twelve month salary support, generous start-up funds and modern well-equipped research facilities are available. Letters of application, including curriculum vitae, a statement of future research interests as well as three letters of reference should be sent by October 1, 1987 to: Dr. Richard J. Courtney, Chairman, Department of Biochemistry and Molecular Biology, L.S.U. Medical Center, 1501 Kings Highway, Shreveport, LA 71130. An Affirmative Action/Equal Opportunity Employer.

Senior Project Leader Natural Environment Research Council Institute of Virology Oxford, United Kingdom

Applications are invited for the position of project leader and on the retirement of the present holder of the post, in the summer of 1988, that of assistant director of the NERC Institute of Virology, Oxford.

Candidates should have a distinguished record of research in molecular virology and some laboratory management experience. Experience in biotechnology would be an advantage. The Assistant Director will be responsible for managing the Institute in the absence of the Director, Professor D.H.L. Bishop, and should therefore have an appropriate scientific reputation. However, the primary responsibility of the successful candidate will be to undertake and develop a program of research in a field of virology that complements the areas currently under investigation in the Institute.

The post will be grade 7 with a salary in the range of f15,030 - 220,292 pounds sterling per annum, depending on experience.

Requests for further particulars and application forms should be sent to: Mrs. J. Shields, NERC, Polaris House, North Star Avenue, Swindon, Wiltshire SN2 1 EU, UK. Telephone: Swindon (0793) 40101 Ext. 472.

The closing date for applications is September 11, 1987. NERC is an Equal Opportunity Employer.


POST DOCTORAL POSITION

The Dana Farber Cancer Institute is seeking to fill one research position at the post doctoral level for a person interested in taking a combined molecular-genetic and biochemical approach to understanding the role of growth factors (aFGF, bFGF, NGF and others) in regulating neural development and differentiation. We are interested in establishing how transmembrane sig- naling events and protein kinases are involved in regulating gene expression and other differentiated properties. Ex- perience in molecular biology and/or protein chemistry is extremely desirable. Send C.V. and names of three references to: Dr. John A. Wagner.

44 Binney St., Boston, MA 02115

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Faculty Position in Biochemistry Medical College of Ohio

The Department of Biochemistry, Medical College of Ohio, invites candidates to apply for a tenure track position at the assistant or associate professor level. The Department is expanding its faculty to include those with research interests that extend its present programs, which include regulation of gene expression, mechanisms of hormone action, protein structure -function relationships, antifolates, protein kineses, posttranslation modification of peptides, peptide hormone analogues, neuroendocrine regulation, membrane receptors, growth factors, and oncogene function. Candidates who employ molecular approaches to their research problems are particularly encouraged to apply. Responsibilities will include establishment of an active research program and participation in the teaching of medical and graduate students. Research facilities within the Department include a core laboratory with state-of-the-art equipment for peptide and oligodeoxynucleotide synthesis, and for protein sequence analysis. Send curriculum vitae, brief summary of research goals, and three letters of reference to:

Dr. James H. Frelsheim Professor and Chairman Department of Biochemistry Medical College of Ohio C.S. 10008 Toledo, Ohlo 43899.

An Equal Oppotinity Employel:

Ceil, Vol. 50, No. 5, August 28, 1987

Biochemistry Faculty Position Nucleic Acid Biochemistry

The Department of Biochemistry, Albert Einstein The Department of Biochemistry, Albert Einstein College of Medicine, is seeking an assistant professor College of Medicine, is seeking an experienced with research interests related to nucleic acid metab- macromolecule crystallographer to develop facilities olism. Areas of research which involve mechanisms of for X-ray crystallography and structural analysis. The regulation, structural aspects of nucleic acid metab- appointee will be involved in the recruitment of olism or enzymology of nucleic acids are preferred. additional faculty who will share the use of the facility. The Department will be adding several faculty in areas Preferred areas of research include protein-nucleic related to nucleic acid metabolism and structural bio- acid structure and enzyme structure, however, other chemistry. Candidates should have completed post- areas will be considered. The faculty rank is open doctoral training and have a strong record of research depending on experience and qualifications. accomplishments. Substantial resources and laboratory Resources are available for development of the research facilities are available. Applicants should facility. Applicants should submit a curriculum vitae, submit a curriculum vitae, references, and a descrip- references, and a description of research plans to: tion of research plans to: Dr. Vern L. Schramm, Dr. Vern L. Schramm, Professor and Chairman of Professor and Chairman of Biochemistry, Albert Biochemistry, Albert Einstein College of Medicine of Einstein College of Medicine of Yeshiva University, Yeshiva University, 1300 Morris Park Avenue, Bronx, 1300 Morris Park Ave., Bronx NY 10461. Applications NY 10461. Applications should be received before should be received before October 30, 1987. October 30, 1987. An Equal Opportunity/Affirmative An Equal Opportuniiy/Afkmative Action Employer. Action Employer.

Biochemistry Faculty Position X-ray Crystallography

ASSOCIATE PROFESSOR, ASSISTANT PROFESSOR AND POSTDOCTORAL POSITIONS

Department o f M icrobiology, Mount Sinai School o f Medicine

are Invited to apply In partsular. mdiwdoals-wth &dependent research achievements III DNA and RNA tumor VIIUS~S and oncogenes are encouraged These efforrs are I” ccadmatlon wth currem ma,or recru,,men,a ,n the newl! created Centers for Molecular B~olog) Neurohtology and Immonobnolog) ar rhe Mom Sina! School of Med~cme

Postdoctorallresearch assw,ate posmons are also dradable ,n the laboratories of the foUowing faculty members I” the Department

Constantin Bona: Regulation of Idiity~determmed munune rqonx, molecular basis for the diversity of anobody response to foreign and autoant~gens. prepara non of idiotype vaccmes

Selins Chcn-Kiang: In wrro RNA transcnpt~on and procwmg. molecular mechamsm of regulatwn of transformmg genes I” human lymphold cells

Ming-Ta Hsu: DNA topology and gene expresxon. DNA tumor r~rology. elec tron rmcroscopy of nucleic acids and nucleopmtem complexes

Edwin D. Kifboume: Influenza vru vaccme and tmmune rcsp~w. genetr deter minatmn of wal virulence

Mark Kryslnl: Viral replxat~on; structure-funcoon relaoonshlpsof wral protens through expre~ion and m ”tagenes,s.

Peter Pnlese: Genera of animal viruses; mecharmm of repbcat~on of influenza wruscs: development of antwirals, molecular epldemlology of v~rws

MOUNT SINAI

cell, Vol. 50, NO. 5, August 28, 1987

Postdoctoral Fellowship Molecular-Cellular Biology University of Vermont

Postdoctoral positions within a strong multidisciplinary center for thrombosis and hemostasis, to study human proteins C and S and their relationship to the prothrom- binase complex (prothrombin, Factors X and v) in model and cellular systems. Studies include gene cloning and DNA sequencing; mRNA analyses of megakaryocytes (platelet progenitors), monocytes/ macrophages and vascular endothelial cells; production and analyses of modified proteins via site-directed mutagenesis/mammalian cell expression; thermo- dynamic and kinetic analyses of protein C/S effects on prothrombin activation on cellular surfaces involving plasma and endogenously-generated protein factors. Experience in at least one of these areas is strongly preferred. Send resume and two reference letters to: Dr. George L Long Department of Biochemistry Unlverslty of Vermont Burllngton, VT 05405. Telephone: (802) 656-0351.

Postdoctoral Position Department of Cell Biology

Postdoctoral position available Fall, 1987 to determine the molecular basis of new mutations that affect glycosylation pathways in Chinese hamster ovary cell mutants. Glycosylation mutants that express a dominant phenotype possibly resulting from gene activation will be studied with highest priority. Once characterized, the mutants provide an ideal approach to cloning glycosylation enzymes by DNA transfection and gene rescue. Salary consistent with experience, begins at $20,000 p.a. Send curriculum vitae and names of three references to: Pamela Stanley, Ph.D., Professor Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461. An Equal Opportunity Employer.

ALBERTEINSTEIN COLLEGE OF MEDICINE

ASSlSTANT PROFESSOR Tenure track position available for Mem- brane Cell Biologist. Preferred areas of research: membrane-cytoskeleton interactions, image reconstruction analyses, in vitro reconstitution of vesicular transport and molecular biology of membrane components. Salary commensurate with training and experience. Candidates are expected to participate in one team taught course in the medical college and in the training of graduate students in cell biology or genetics. To apply, send CV and a brief summary of research interests to: Dr. Donald Fischman, Chairman Dept. of Cell Biology and Anatomy

Cornell University Medical College 1300 York Avenue New York, New York 10021

Applications should be received by September 15. 1987 EEOIAAIMIFIHIV

Postdoctoral Position in Signal Transduction and

Cytoskeleton-Membrane Interaction:

Appllcallons are invited for a postdoctoral position available in the Fall, 1987 In a group of laboratories involved in projec

relating to signal transduction mechanisms, cytoskeletal- membrane Interactions, malignant transformation and the relatlonshlp of these processes. Preceptors Include

members of the Departments of Anatomy and Structural Biology, Molecular Pharmacology, Pathology, and Molecula

Biology. Techniques include molecular genetics. tissue

culture, protein blcchemlstty, Immunocytochemlstry. and eleclron mlcroscopy. This Is an NIH Training grant posltlon.

SlIpend according to experience and NIH guidelines.

Applicants should direct Inquiries including currlculw

Vitae and names of three references to:

Dr. Peter Satir, Chairman, Department of Anatomy and

Structural Biology, Albert Einstein College of MediChe,

1300 Morris Park Avenue, Bronx, NY 10461.

An Equal Opportunity Employer.

ALBERTENSTEIN COLLEGE OF MEDICINE

Cell, Vol. 50. No. 5, August 28, 1987

Postdoctoral Fellows Tufts University

Positions for two NIH funded postdoctoral fellows are available to study virological models of B cell differentiation in humans using Epstein-Barr virus (EBV) and in mice using Abelson Murine leukemia virus (A-MLV). Areas of study range from molecular biology and protein chemistry to immunology. A background in molecular biology is preferable. Send a curriculum vitae and letter of reference to:

Dr. Naomi Rosenberg (A-MLV) or Dr. David Thoriey-Lawson (EBV) Department of Pathology Tufts University School of Medicine 136 Harrison Avenue Boston, MA 02111.

Postdoctoral Fellowships Neurovirology and Neuroimmunology The University of Pennsylvania

Positions available Winter, 1987 under an NIH training grant. Candidates can choose a research program with one of ten trainers from the Departments of Microbiology, Neurology, or Pathology at the University of Pennsylvania, or the Wistar institute. Areas of investigation include: molecular virology, viral pathogenesis, viral and host genetics, autoimmune CNS disease, viral immunopathology and persistent infections. Send curriculum vitae and three references to:

Dr. Neal Nathanson Department of Microbiology School of Medicine University of Pennsylvania 209 Johnson Pavilion Philadelphia, PA 19104-6076 Telephone: 215-898-8011.

An Equal Opportunity Employer.

Staff Scientists lnstitut du Cancer de Montreal

The lnstitut du Cancer de Montreal invites applications for several appointments as staff scientists. The preferred fields of research are onto-developmental biology, tissue-specific gene expression, and the molecular biology of oncogenes. A Ph.D. or M.D., relevant postdoctoral experience, and the ability to carry out an independent research program are required. The Institu, du Cancer de Montreal is affiliated with the Universitb de Montreal and is located within Notre-Dame Hospital in downtown MontrBai. The current basic research group consists of ten independent staff scientists with diverse interests within the fields of molecular biology, cancer virology, and the biology of development. The working languages of the Institute are French and English. Candidates for this position may be eligible for a two year income tax exemption offered by the Government of Qu6bec to new scientific personnel. Please submit your curriculum vitae, present and future research plans, and the names and addresses of at least three references to: Dr. Daniel Skup, Scientific Director institut du Cancer de Mont&al, 1560 Sherbrooke Street East, Montreal, Quebec, H2L 4M1, Canada.

Molecular/Cellular Neurobiologist Department of Anatomy and Cell Biology UCLA Medical School

The Department of Anatomy and Cell Biology at the University of California Los Angeles, invites applications for a tenure track faculty position that is currently available at the assistant professor level. Applicants must have either an M.D. or Ph.D. degree and research experience in molecular or cellular neurobiology. A background or interest in neuroendocrinology is preferred. The position includes participation in the departmental teaching program. Please send curriculum vitae, a brief letter describing your research program, and the names of three references to:

Dr. Richard W. Young Department of Anatomy and Ceil Biology UCLA Medical School Los Angeles, CA 90024-1763.

UCLA is an Aftkmatiw Action/Equal Opportunity Employer.

Cell,Vol. 50. No. 5.August28, 1987

Senior Scientist Molecular Genetics Hoffmann - La Roche

The Department of Molecular Genetics, Roche Research Center, Hoffmann-La Roche, Inc. seeks a senior scientist who will be responsible for a basic research program in eukaryotic molecular biology and participate in research projects using recombinant DNA technology. The Department conducts basic and applied research on prokaryotic and eukaryotic gene expression, retroviruses, lymphokines, oncogenes, growth factors, and other areas with relevance to human pharmaceuticals. Qualifications include a Ph.D. in molecular biology, biochemistry, or virology and a minimum of two years postdoctoral training. Individuals with experience in retroviral gene regulation or eukaryotic expression systems are encouraged to apply. The Roche Research Center is located in a suburban setting 10 miles from New York City.

Roche offers a very competitive compensation package and a research environment that encourages scientific growth. Interested individuals should send curriculum vitae and a letter indicating past, current, and future research interests to:

Dr. Peter Lomedico Director, Department of Molecular Genetics Uoche Research Center Hoffmann-La Roche, inc. Nutley, NJ 07110.

Hoffmann-La Roche is an Equal Opportunity Employer.

Research Opportunities

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Postdoctoral Fellowships University of W isconsin School of Medicine

Two postdoctoral positions are available to study the regulation of glucose metabolism-induced insulin release in the pancreatic islet. Studies involve recombinant DNA technology as well as traditional biochemical approaches.

Please send curriculum vitae and names of references to:

Dr. Michael J. MacDonald University of Wisconsin Medical School 1300 University Avenue Madison, W I 53706.

The University of Wisconsin is an Equal Opportunity Employer.

@Jyale UNIVERSIm ‘C a <, “ill+ Cellular Neurobiologist or Cell Biologist

The Department of Biology at Yale University wishes to appoint an assistant professor with an established research interest in Cellular Neurobiology or Cell Biology. The successful applicant is expected to conduct a vigorous research program, interact with a diverse group of cellular and developmental neuro- biologists and cell biologists, and teach effectively at graduate and undergraduate levels, Send curriculum vitae, description of research, and names and addresses of at least three references by October 1, 1987 to:

Chairman, Department of Biology Yale University PO Box 6666

New Haven, CT 06511. Yale University is an Equal Opportunity/Aftirmative Action Employer. Women and members of minority groups are urged to apply.

POSTDOCTORAL POSITION

in Eukaryotic Gene Regulation

The Salk Institute for Biological Studies

Qualified individuals interested in molecular approaches to the developmental regulation of gene expression are sought for a postdoctoral position to study regulation of the human glycoprotein hormone genes. Aspects of the studies include approaches to questions in reproduction, development, oncogenesis, hormonal regulation (both second messenger and steroid hormone regulation), and transcriptional control. Projects include characterization of interdependent and complex enhancer sequences and the trans-acting factors with which they interact. Specific approaches include gene transfer to cells in culture, transgenic mice, in vitro transcription, affinity chromatography for the purification of transcription factors, and DNAse footprinting.

Interested individuals please send curriculum vitae and names of references to:

Pamela Mellon, Ph.D. Assistant Professor

The Salk Institute 10010 N. Torrey Pines Road

La Jolla, California 92037 (619) 453-4100 x209.

positions available

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