pooria gill phd of nanobiotechnology [email protected] stm applications in biomedicine in the...

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Pooria Gill PhD Of Nanobiotechnology [email protected] STM Applications in Biomedicine In The Name of Allah

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Page 1: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

Pooria GillPhD Of Nanobiotechnology

poor iagi l [email protected]

STM Applications in Biomedicine

In The Name of Allah

Page 2: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

Nanoscopy of Nanostructured Biomolecules

Structural AnalysesInteractiomicsPartial SequencingImmobilization CharacterizationPeptide CharacteristicsMicrobial CharacteristicsViral Characteristics…

Page 3: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

Single strand of calf thymus DNA deposited along a surface step of HOPG. (50 x 50 nm, constant current mode, current 0.1 nA, bias voltage 500 mV.)

Methods In Molecular Biology, Vol 22. Microscopy, Opt/cat Spectroscopy, and Macmscop/c Technrqoes Edlted by: C Jones, I3 Mulloy, and A H. Thomas Copynght 01994 Humana Press Inc., Totowa, NJ.

Page 4: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

STM of λ-DNA (GeneRuler DNA) on HOPG

P. Gill, B. Ranjbar, R. Saber. IET Nanobiotechnol., 2011, Vol. 5, Iss. 1, pp. 8–13.

Page 5: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

3D image of a single antibody (IgG) molecule after the filtering and coloring process, which shows orientation of this molecule after physical adsorption on the

rigid surface from the hinge region imaged by NAMA-STM

R. Saber, S. Sarkar, P. Gill, B. Nazari, F. Faridani. Scientia Iranica F (2011) 18 (6), 1643–1646.

Page 6: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

3D image of a single antibody (IgM) molecule, imaged by NAMA-STM. (b) Standard configuration of human immunoglobulin M with pentameric domains

R. Saber, S. Sarkar, P. Gill, B. Nazari, F. Faridani. Scientia Iranica F (2011) 18 (6), 1643–1646.

Page 7: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

STM images of antiferritin antibodies passively adsorbed to a microwell surface

STM images of biotinylated antiferritin antibodies immobilized to a

streptavidin coated microwell surface

STM comparison of passive antibody adsorption and biotinylated antibody linkage to streptavidin on microtiter wells

Davies et al., Journal of Immunological Methods, 167 (1994) 263-269.

Page 8: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

Individual Peptide Structures Visible by STM

Page 9: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

Reconstructed surface topography of coated T4 polybead capsomeres; (a) the TEM and (b) STM representations. The slight variation in the representation may be due to the overlying carbon

film, which is observed by STM but not by TEM. Height range is 2.3 nm. (Reprinted with permission from Stemmer et al., 1989.)

M. FIRTEL and T. J. BEVERIDGE. Scanning Probe Microscopy in Microbiology. Micron, Vol. 26, No. 4, pp. 347-362, 1995.

Page 10: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

Reconstructed surface topography of coated T4 polybead capsomeres; (a) the TEM and (b) STM representations. The slight variation in the representation may be due to the overlying carbon

film, which is observed by STM but not by TEM. Height range is 2.3 nm. (Reprinted with permission from Stemmer et al., 1989.)

M. FIRTEL and T. J. BEVERIDGE. Scanning Probe Microscopy in Microbiology. Micron, Vol. 26, No. 4, pp. 347-362, 1995.

Page 11: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

STM image of coated (a) sheath and (b) hoops from M. hungatei. Bars: x, y = 100 nm; z = 8 nm.

M. FIRTEL and T. J. BEVERIDGE. Scanning Probe Microscopy in Microbiology. Micron, Vol. 26, No. 4, pp. 347-362, 1995.

Page 12: Pooria Gill PhD Of Nanobiotechnology pooriagill@yahoo.com STM Applications in Biomedicine In The Name of Allah

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