Postgraduate Medical Journal

EditorA. A. G. LEWIS B.Sc. M.D. F.R.C.P.

Advisory Editorial BoardA. G. Apley F.R.C.S.D. Barltrop B.SC. M.D. M.R.C.P. D.C.H.E. M. M. Besterman M.A. M.D. F.R.C.P.E. H. Brown D.M. M.R.C.P. D.C.H.A. E. R. Buckle F.R.C.S. F.R.C.O.O.J. 0. Caig F.R.C.S.I. D.M.R.D. F.F.R.A. H. Crisp M.D. M.R.C.P.E. D.P.M.Sir Robert Drew K.C.B. C.B.E., F.R.C.P, F.R.A.C.P.H. Ellis M.A. D.M. F.R.C.S.R. Goulding B.SC. M.D. F.R.C.P.

B. I. Hoffbrand M.A., D.M., M.R.C.P.J. P. Hopewell F.R.C.S.D. G. James M.A. M.D. F.R.C.P.S. B. Karani D.P.H. F.R.C.P. F.A.C.C.P.C. E. Newman C.B.E. M.D. F.R.C.P.K. L. Nissen F.R.C.S.J. W. Paulley M.D. F.R.C.P.T. A. J. Prankerd M.D. F.R.C.P.D. A. Pyke M.D. F.R.C.P.P. K. Thomas B.SC. M.D. F.R.C.P.P. Turner B.SC. M.D. M.R.C.P.

Editoril Representatve for North AmericaCharles G. Roland M.D.

Editorial Representative for AustrliProfessor Thomas Stapleton M.A. D.M. M.R.C.P. D.C.H.

Editorial A tMrs M. E. Coops B.SC.

Postgraduate Medical Journal is published monthlyfor the Fellowship of Postgraduate Medicine byBlackwell Scientific Publications Ltd. The annualsubscription is £8.00 ($27.00) post free, and the priceof single issues 90p ($3.00) postage extra. Ordersfor back issues published up to December 1966 andcorrespondence from Fellows and Associates shouldbe sent to The Secretary, The Fellowship of Post-graduate Medicine, 9 Great James Street, London,W.C.1 (tel: 01-242 6900); other orders andbusiness correspondence should be addressed toBlackwell Scientific Publications Ltd, 5 Alfred Street,Oxford OX1 4HB (tel: Oxford 40201).

All editorial correspondence should be addressedto Dr A. A. G. Lewis, The Postgraduate MedicalJournal, 9 Great James Street, London, W.C.1(tel: 01-242 6900).

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The Fellowship of Postgraduate Medicine wasfounded by a group of London consultants after theFirst World War to assist postgraduates, particularlythose coming to London from the Commonwealth,to pursue their studies. The Fellowship first publishedthe Postgraduate Medical Journal to give informa-

tion about lectures, conferences and courses and toprovide a monthly review ofall branches of medicine.

Postgaduate Medical Journal publishes originalpapers on subjects of current clinical importanceand welcomes review articles with extensive, up-to-date bibliographies as guides to further reading.Several symposia are published every year, eachdevoted to a single subject and written, by invitation,by specialists in different disciplines. Most issuesinclude authoritative Current Surveys of clinicalproblems, as well as well-documented Reports ofcases of particular interest, Correspondence andBook Reviews.A 'Notice to Contributors' is published on the

inside back cover of this issue. The Editor reservesthe right to make changes which may clarify orcondense papers where this is considered desirable.

© The contents of this Journal are copyright and,subject to the provisions of Section 7 of the Copy-right Act, 1956, they may not be copied, adapted orreproduced without permission. Requests for per-mission to reproduce material elsewhere, either inwhole or in part, should be addressed to the Editor,Postgraduate Medical Journal, 9 Great James Street,,London, W.C.1.

Postgraduate Medical Journal (December 1971) 47, 823-824.

Books receivedModern Radiotherapy-Gynaecological Cancer. Edited byTHOMAS J. DEELEY. Pp. 324, illustrated. London: Butter-worths, 1971. £5.00.

Law Relating to Hospitals and Kindred Institutions. ByS. R. SPELLER. Pp. 782. London: H. K. Lewis and Co.,Ltd, 1971. £9.50.

Pathology Annual: 1971. Vol. 6. By SHELDON G. SOMMERS.Pp. 576, illustrated. London: Butterworths, 1971. £7.50.

Scoliosis and Growth. Edited by P. A. ZORAB. Pp. 154, illus-trated. Edinburgh: Churchill Livingstone, 1971. £4.00.

Cardiology: A Clinicophysiologic Approach. Edited by S. M.AYRES and J. J. GREGORY. Pp. 667, illustrated. London:Butterworths, 1971. £6.80.

Schizophrenia in Children. By J. L. DESPART. Pp. 215.London: Butterworths, 1971. £3.00.

The Interface between Psychiatry and Anthropology. Edited byTAGO GALDSTON. Pp. 150. London: Butterworths, 1971.£3.00.

The Briefer Psychotherapies. By LEONARD SMALL. Pp. 262.London: Butterworths, 1971. £3.25.

Psychiatric Emergencies: Diagnosis and Management. ByP. K. BRIDGES. Pp. 195, illustrated. U.S.A.: CharlesThomas, 1971. $12.00.

Choriocarcinoma-A Study of its Pathology. By W. W. PARK.Pp. 214, illustrated. London: William Heinemann MedicalBooks Ltd, 1971. £3.00.

Recent Results in Cancer Research. Endolymphatic Radio-therapy in Malignant Lymphomas. By S. CHIAPPA, R.MUSUMECI and C. USLENGHI. Pp. 129, illustrated. London:William Heinemann Medical Books Ltd, 1971. £6.90.

The Human Adipose Cell. A Model for Errors in MetabolicRegulation. By DAVID G. GALTON. Pp. 220, illustrated.London: Butterworths, 1971. £4.00.

New EditionsShort Practice of Surgery. By BAILEY and LOVE, revised by

A. J. HARDING RAINS and W. MELVILLE CAPPER. Fifteenthedition. Pp. 1296, illustrated. London: H. K. Lewis andCo., Ltd, 1971. £6.50.

Samson Wright's Applied Physiology. Revised by CYRIL A.KEELE and ERIC NEIL. Twelfth edition. Pp. 576, illustrated.Oxford: Oxford University Press, 1971. £3.50.

General Anaesthesia. Vol. 1 and '. Edited by T. CECIL GRAYand J. F. NUNN. Third edition. Pp. 736 and 773, illustrated.London: Butterworths, 1971. £16.00 each.

Clinical Disorder of Iron Metabolism. By V. F. FAIRBANKS.Second edition. Pp. 486, illustrated. U.S.A.: Grune andStratton, Inc., 1971. $25.00.

Williams Obstetrics. By L. M. HELLMAN and J. A. PRITCHARD.Fourteenth edition. Pp. 1242, illustrated. New York:Appleton-Century Crofts; London: Butterworths, 1971.£10.50.

Book reviewsManagement of Renal Failure

Edited by M. D. MILNE. Pp. 190, illustrated. London:British Council, 1971. £2.00.

In a very rapidly advancing field this comprehensive, yetessentially practical review of the current management ofrenal failure, will be of great value to the nephrologist andto the general physician. There is inevitably some repetitiondue to overlap between the articles, but there is very littleconflict of opinion in terms of practical management.The opening article by 0. Wrong covers very completely

the diagnosis and treatment of acute uraemia, and dealshelpfully with common but knotty problems such as thediagnosis of salt depletion, and the misuse of alkalis inuraemic acidosis. Recent developments in investigationreceive timely, critical appraisal in the contributions byP. Clark on 'Surgical Aspects of Chronic Renal Failure', andby 1. Kelsey Fry and W. R. Cattell on 'Radiology in theDiagnosis of Renal Failure'. The latter includes a useful dis-cussion on the surgical and medical treatment of renal stones.T. M. Barratt, in 'Renal Failure in the First Year of Life'emphasizes important problems in diagnosis and treatment,peculiar to infants, and his contribution, together with thatof R. Shackman and A. E. Kulatilake include helpful adviceon the technique of peritoneal dialysis in children. Thespectrum of renal diseases in the tropics, and the differentapproach necessitated by socio-economic and geographicalfeatures is dealt with by M. S. R. Hutt and A. J. Wing, andmakes reading not only fascinating, but of practical im-portance in days of rapid travel. One of the highlights is theexcellent article by J. J. Brown et al. on the mechanisms ofhypertension in renal failure, which manages to make acomplicated subject, if not simple, at least understandable;they suggest, with much experimental backing, cogentreasons why hypertension in some patients on chronicdialysis is controllable, and in others uncontrollable. Themechanisms of anaemia in renal failure, with particular

emphasis on the role of erythropoietin, and on micro-angio-pathic haemolytic anaemia, are authoritatively reviewed byD. G. Penington and Priscilla Kincaid-Smith. F. O'Gradyprovides a thoughtful, scientific discussion of factors affectingthe effective concentration of antibiotics, followed by somepractical guide-lines for assessment of dosage of drugseliminated by the kidneys in patients with renal failure.J. Siddiqui and D. N. S. Kerr in their article on complicationsof renal failure include a good review of renal bone disease,substantiated by many references. In addition some of thelittle recognized complications, such as myopathy, receivetimely emphasis. The controversial question of the optimalprotein intake in renal failure is discussed by J. D. Blaineyand M. J. Chamberlain in 'Dietary Treatment of ChronicRenal Failure'. It is perhaps a pity that such scant referenceis made to the dietary management of the diabetic with renalfailure. The concluding articles on dialysis in hospital and athome by J. H. Jones, J. R. Curtis, and B. H. B. Robinson, andon transplantation by J. Swihney bring one up-to-date oncurrent techniques, complications, facilities, costs andmortality.

Recent Advances in PaediatricsEdited by D. GAIRDNER and D. HULL. Fourth edition.Pp. 567, illustrated. London: J. and A. Churchill, 1971.£6.00.

This is the fourth edition in the series which began in 1954.It comprises fifteen chapters, each of which is devoted to asingle aspect of paediatrics and might almost be regarded asa short monograph in its own right. The references cited arenumerous and have in this edition reached the prodigioustotal of 2500. A wide range of topics are covered and thefoetus and neonate are prominent among them, with sectionson neonatal respiration, foetal growth, asphyxia neonatorum,the respiratory distress syndrome, haemolytic disease and aninteresting section on the care of infants in incubators. Other

Subject Index

PageAbdominal injuries, multiple ... Tension pneumo-

peritoneum as a post-operative complication of.. . D. Keowen and K. Cronin 131

Abnormalities . . . Multiple unusual . . . in theelectrocardiogram in myxoedema ... J. de Swiet 626

Accessory artery in essential hypertension ... BoonSeng Ooi, Beatrice T. M. Cheng, Sheng Fong Yuand Oon Teik Khoo 197

Acetone in uncontrolled diabetes . .. M. J. Sulway,M. D. Trotter, E. Trotter and J. M. Malins 382

Acid/base . . . Blood . . . studies and urinary acidexcretion in obese fasting patients ... S. K. Ross,R. E. G. Dale, W. S. T. Thomson and J. T.Ireland 447

Acid excretion . . . Blood acid base studies andurinary ... in obese fasting patients ... S. K.Ross, R. E. G. Dale, W. S. T. Thomson andJ. T. Ireland 447

Acid, hydrochloric-Metabolic alkalosis treatedwith intravenous . . . F. X. M. Beach and E.Sherwood Jones 516

Acidotic-Non-keto-. . . diabetic coma ... J. V.Collins and P. W. R. Harris 388

Acidosis . . . Haemodialysis in the treatment oflactic ... associated with acute hepatic and renalfailure ... A. Colombi and H. Tholen 628

Acquired haemolytic anaemia during the earlypuerperium ... A case of ... T. Singh 156

Action-hypoglycaemic. . . The ... of metformin... K. N. Frayn, P. I. Adnitt and Paul Turner 777

Active chronic hepatitis ... Fibrosing alveolitis and... without hyperglobulinaemia ... R. B. Huddyand A. Ahmed 363

Active chronic hepatitis and haemolytic anaemiaassociated with Rh-specific antibodies ... C. D. R.Pengelly and R. C. Jennings 683

Activity-Hepatitis and . .. Dennis M. Krikler 490Acute hepatic failure-The management of . . .

Sheila Sherlock and S. P. Parbhoo 493Addicts-Viral hepatitis in drug . . . Susan F.

Sullman and A. J. Zuckerman 473Adenomatosis-multiple, presenting with psychia-

tric manifestations . . . M. W. P. Carney, I.Weinbren, F. Jackson and G. V. Purnell 242

Aetiological-Psychological factors in asthma: areview of their . .. and therapeutic significance 533

Aetiology-The multiple .. . of viral hepatitis 476African patients ... Clinical experience with metol-

azone in fifty-two ... : synergy with frusemide. . . R. F. Gunstone, A. J. Wing, H. G. P. Shani,D. Njemo and E. M. W. Sabuka 789

Aged South African Bantu consuming a diet low incalcium, Metacarpal bone dimensions in youngand . . . Alexander R. P. Walker, B. F. Walkerand B. D. Richardson 320

Alkalosis-The use of amiloride hydrochloride inthe correction of hypokalaemic . .. induced bydiuretics . . . A. C. Antcliff, D. G. Beevers, M.Hamilton and J. E. Harpur 644

PageAlkalosis-Metabolic ... treated with intravenous

hydrochloric acid . . . F. X. M. Beach and E.Sherwood Jones 516

Alveolitis-fibrosing ... and active chronic hepa-titis without hyperglobulinaemia ... R. B. Huddyand A. Ahmed 363

Amantadine hydrochloride in extra-pyramidal dis-orders ... L-Dopa and ... J. D. Parkes, R. P.Knill-Jones and P. J. Clements 116

Amiloride hydrochloride-The use of . . . in thecorrection of hypokalaemic alkalosis induced bydiuretics . . . A. C. Antcliff, D. G. Beevers, M.Hamilton and J. E. Harpur 644

Amoebiasis ... Radiological changes in hepatic ...S. Ramachandran, D. L. N. Jayawardena andJ. R. A. Perumal 615

Amoebic pericaiditis . . . B. C. Bansal and D. S.Gupta 678

Amyloidosis-secondary . . . in relation to car-cinoma of the kidney ... David Spencer 820

Anaemia-Active chronic hepatitis and haemolytic... associated with Rh-specific antibodies 683

Anaemia-aplastic... with carcinoma ofthe thyroid... C. C. Smith and A. J. King 161

Anaemia-Haemocytic periodicity and periodicdisorders: Periodic neutropenia, thrombocyto-penia, lymphocytosis and . . . Hobart A. Rei-mann 504

Anaemia-haemolytic ... A case of acquired ...during the early puerperium . . . T. Singh 156

Aneurysms ... David J. Tibbs 270Aneurysms-Fusiform ... of the brachial artery ina child treated by proximal ligation . . . J. F.Colin and Harold Ellis 323

Aneurysms-intracranial ... Use of an anti-fibrino-lytic agent (tranexamic acid) in the managementof ruptured ... J. R. Gibbs and A. G. L. Corkill 199

Anorexia nervosa . . The relationship betweensleep, nutrition and mood: a study of patientswith . . . A. H. Crisp, Edward Stonehill andGeorge W. Fenton 207

Anti-arthritic drugs . . . Gastric ulcer and the ...J. H. Emmanuel and R. D. Montgomery 227

Antibodies-Active chronic hepatitis and haemo-lytic anaemia associated with Rh-specific . . .

C. D. R. Pengelly and R. C. Jennings 683Anticoagulants . . . Mitral valve disease, systemicembolism and ... H. A. Fleming and Sheila M.Bailey 599

Antidiuretic-Inappropriate secretion of . .. hor.mone in Guillain-Barre syndrome ... Aeron G.Davies 651

Antigen-A review of the present position ofAustralia ... F. 0. MacCallum 481

Antigen-Electron microscopic observations andspeculations on Australia . .. June D. Almeida 484

Anti-fibrinolytic agent (tranexamic acid) in themanagement of ruptured intracranial aneurysms-Use of an ... J. R. Gibbs and A. G. L. Corkill 199

iv Postgraduate Medical Journal

Anti-tuberculosis drugs ... Problems of drug resis-tance in tuberculosis-the newer ... John Crofton 748

Antrum ... Carcinoma of the gastric ... in identicaltwins ... Frank I. Lee 622

Aplastic anaemia with carcinoma of the thyroid ...C. C. Smith and A. J. King 161

Appraisal-An ... of hypnosis ... H. Merskey 572Arterial injuries and their management ... G. Slaneyand F. Ashton 257

Arterial-Limb salvage ... surgery for gangrene ...G. W. Taylor 251

Artery-Fusiform aneurysms of the brachial ... ina child treated by proximal ligation ... J. F. Colinand Harold Ellis 323

Artery-the accessory-in essential hypertension... Boon Seng Ooi, Beatrice T. M. Cheng, ShengFong Yu and Oon Teik Khoo 197

Asthma ... Biochemistry and rheology of sputumin ... E. E. Keal 171

Asthma . . . Bronchial lavage in . . . Norton E.Williams 188

Asthma ... The immunological aspects of... H. E.Amos 166

Asthma and mites ... A. W. Frankland 178Asthma-Psychological factors in . . .: a review of

their aetiological and therapeutic significance ...Samuel I. Cohen 533

Asthma . . . The physiology and management ofchildhood . .. R. S. Jones 181

Atrial-left-myxoma in a child diagnosed byultra-sound ... A. J. S. Nicholls, M. A. Goodmanand R. B. Pridie 804

Atrophy ... Complete heart block in patients withperoneal muscular . . . B. A. J. Ponder, K.Chatterjee and G. C. Sutton 595

Australia antigen-A review of the present positionof... F. 0. MacCallum 481

Australia antigen-Electron microscopic observa-tions and speculations on . .. 484

Axial osteomalacia ... John R. Condon and J. R.Nassim 817

Back-low-and leg pain due to presumptive pro-lapsed intervertebral disc-The results of surgeryfor ... G. E. Dunkerley 120

Bantu-South African-Metacarpal bone dimen-sions in young and aged ... consuming a diet lowin calcium . . . Alexander R. P. Walker, B. F.Walker and B. D. Richardson 320

Basic psychosomatic concepts . .. Heinz H. Wolff 525BCG vaccination . . . Future policy for . . . in

Britain ... Ian Sutherland 756Biochemistry and rheology of sputum in asthma ...

E. E. Keal 171Bladder-the urinary-Phaeochromocytoma of ...

with acute oliguric renal failure: the use of aplasma catecholamine assay in diagnosis . . .

M. J. Goggin, J. Finberg, A. R. Adamson andA. M. Joekes 238

Block-complete heart-in patients with peronealmuscular atrophy ... B. A. J. Ponder, K. Chatter-jee and G. C. Sutton 595

Blood acid/base studies and urinary acid excretionin obese fasting patients ... S. K. Ross, R. E. G.Dale, W. S. T. Thomson and J. T. Ireland 447

Blood sugar-Insulin . . . and hunger . . . TrevorSilverstone and Michael Besser 427

Bone dimensions-metacarpal-in young and agedSouth African Bantu consuming a diet low incalcium . . . Alexander R. P. Walker, B. F.Walker and B. D. Richardson 320

Brachial artery-Fusiform aneurysms of the .. . ina child treated by proximal ligation 323

Brent-Tuberculosis in . . . M. W. McNicol andJ. R. Mikhail 691

Bristol-Infectious hepatitis in. . . , 1959-70 462Britain-Future policy for BCG vaccination in ...

Ian Sutherland 756Bronchial lavage in asthma ... Norton E. Williams 188Burkitt's lymphoma-Immunological studies on

.. . George Klein 141Businessmen-The dietary sugar intake of . . .:The results of a cross-sectional survey . . . J. F.Richardson 423

Calcium-Metacarpal bone dimensions in youngand aged South African Bantu consuming a dietlow in ... Alexander R. P. Walker, B. F. Walkerand B. D. Richardson 320

Carbenoxolone sodium-Hypokalaemic myopathyand myoglobinuria due to . .. P. C. Barnes andJ. H. C. Leonard 813

Carcinoma of the gastric antrum in identical twins... Frank I. Lee 622

Carcinoma-Secondary amyloidosis in relation to... of the kidney ... David Spencer 820

Carcinoma of the thyroid-Aplastic anaemia with... C. C. Smith and A. J. King 161

Cardio-respiratory failure-Obesity with . . . P.Dinda, W. D. Riding, S. S. Chatterjee 158

Carotid-vertebral-Surgical aspects of . . . in-sufficiency . . . J. A. Gillespie 282

Case of acquired haemolytic anaemia during theearly puerperium-A ... T. Singh 156

Catecholamine assay-Phaeochromocytoma of theurinary bladder with acute oliguric renal failure:the use of a plasma . . . in diagnosis . . . M. J.Goggin J. Finberg, A. R. Adamson and A. M.Joekes 238

Cause or coincidence?-Gallstones and flatulentdyspepsia: ... Alan G. Johnson 767

Cerebral oedema associated with hyponatraemia inrenal failure . . . K. K. Arora, M. J. Brummitt,Joanna Sheldon and J. A. P. Trafford 365

Cervical-Tuberculous ... lymphadenopathy ...J. F. Newcombe 713

Changes-Radiological . . . in hepatic amoebiasis... S. Ramachandran, D. L. N. Jayawardena andJ. R. A. Perumal 615

Chest disease-Clindamycin levels in sputum in apatient with purulent ... due to cystic fibrosis ...J. A. Raeburn and J. G. Devine 366

Index to Volume 47 v

Child-Fusiform aneurysms of the brachial arteryin a . . . treated by proximal ligation . . . J. F.Colin and Harold Ellis 323

Child-Left atrial myxoma in a ... diagnosed byultra-sound ... A. J. S. Nicholls, M. A. Good-man and R. B. Pridie 804

Child-Osteogenesis imperfecta in a... presentingwith neurological features ... N. A. P. Evans 512

Childhood asthma-The physiology and manage-ment of ... R. S. Jones 181

Children-Plasma lipids in obese . . . treated with350 Kcal diets ... Audrey S. Fosbrook, C. D. G.Brook and June K. Lloyd 444

Chloropropamide therapy-A massive lipoma in apatient receiving ... Henry A. Garfinkel 137

Cholangitis-Primary sclerosing . . . LaurenceTinckler 666

Chronic hepatitis-Active . . . and Hemolyticanaemia associated with Rh-specific antibodies 683

Chronic renal failure-Psychiatric disturbance in. . . and its treatment by dialysis ... J. DonovanHailstone 549

Chronic hepatitis-Fibrosing alveolitis and active... without hyperglobulinaemia ... R. B. Huddyand A. Ahmed 363

Clindamycin levels in sputum in a patient withpurulent chest disease due to cystic fibrosis ...J. A. Raeburn and J. D. Devine 366

Clinical experience with metolazone in fifty-twoAfrican patients: synergy with frusemide ... R. F.Gunstone, A. J. Wing, H. G. P. Shani, D. Njemoand E. M. W. Sabuka 789

Clioquinol-Raised serum protein-bound iodineafter topical ... A. C. Upjohn, H-J. B. Galbraithand Bethel Solomons 515

Coincidence-Gallstones and flatulent dyspepsia:cause or ... ? Alan G. Johnson 767

Colchicine-self-poisoning with ... M. G. Ellwoodand G. H. Robb 129

Colon-Pneumatic rupture of . . . Raj Kumar, T. R.Rowe and R. B. Dave 631

Coma-A critical appraisal of mechanisms con-cerned in non-ketotic hyperosmolar diabetic ...W. P. U. Jackson 399

Coma-diabetic-The management of... over one-third of a century ... W. G. Oakley 48

Coma-hypoglycaemic-after partial gastrectomy... P. A. Bacon and A. B. Myles 134

Coma-Non-keto-acidotic diabetic ... J. V. Collinsand P. W. R. Harris 388

Comas-Diabetic ... T. D. R. Hockaday 376Combined degeneration-Subacute ... of the spinal

cord in a vegan ... H. N. Misra and J. M. Fallow-field 624

Comparison of propanolol and LB 46 (prinodolol)on hyperthyroid tachycardia . . . A. G. Arbaband P. Turner 329

Complete heart block in patients with peronealmuscular atrophy ... B. A. J. Ponder, K. Chatter-jee and G. C. Sutton 595

Concepts, current, of Parkinsonism ... John Pearceand Iris Pearce 794

Congenital-Non-cardiac morphological stigmataof ... heart disease ... Brian Livesley 800

Considerations, general, in intermittent drugtherapy of pulmonary tuberculosis . . . WallaceFox 729

Cord, spinal-Subacute combined degeneration ofthe ... in a vegan ... H. N. Misra and J. M.Fallowfield 624

Coronary care-intensive, in a regional hospital,experiences of .. . P. M. McAllen 5

Coronary care-A review of current and futuretrends in ... J. Shillingford 23

Coronary care unit-Some nursing problems in ...Elizabeth S. Mendelssohn 3

Coronary heart disease-Obesity and . . . I.McLean Baird 30

Correction of-The use of amiloride hydrochloridein the . . . hypokalaemic alkalosis induced bydiuretics ... A. C. Antcliff, D. G. Beevers, M.Hamilton and J. E. Harpur 644

Critical appraisal of mechanisms concerned in non-ketotic hyperosmolar diabetic coma, a . . .W. P. U. Jackson 399

Current concepts of Parkinsonism ... John Pearceand Iris Pearce 794

Cystic fibrosis-Clindamycin levels in sputum in apatient with purulent chest disease due to . . .J. A. Raeburn and J. D. Devine 366

Deep vein thrombosis ... G. E. Mavor 311Degeneration-Subacute combined. . . of the spinal

cord in a vegan . . . H. N. Misra and J. M.Fallowfield 624

Diabetes-Acetone in uncontrolled . .. M. J. Sul-way, M. D. Trotter and J. M. Malins 382

Diabetes-Haemochromatosis and . . . I. W.Dymock and Roger Williams 79

Diabetes-Hyperosmolar non-ketotic ... MichaelB. Macaulay 191

Diabetes-Lipoprotein and fibrinogen studies in... A. Hart, J. M. Thorp and H. Cohen 435

Diabetes mellitus and hypothyroidism-. . . J. F.Bridgman 781

Diabetes mellitus and pregnancy (abstract) . . . J.Pedersen 66

Diabetes-Men, women and ... D. A. Pyke 54Diabetes-Obesity and ... Arnold Bloom 430Diabetes and vascular surgery ... L. T. Cotton,D. I. R. Higton and H. E. Berry 84

Diabetic coma-A critical appraisal of mechanismconcemed in non-ketotic hyperosmolar . . .W. P. U. Jackson 399

Diabetic coma-The management of ... over one-third of a century ... W. G. Oakley 48

Diabetic coma-non-keto-acidotic . . . J. V. Collinsand P. W. R. Harris 388

Diabetic comas ... T. D. R. Hockaday 376Diabetics' eyes-Forty years looking at . . . T. H.

Whittington 62Diagnosis of pulmonary embolism: a review with

particular reference to the use of radionuclides,The ... David J. Cook and Harry Lander 214

vi Postgraduate Medical Journal

Diagnostic procedure-Mediastinoscopy: a ... inhilar and paratracheal lymphadenopathy . . .

J. R. Mikhail, D. N. Mitchell and I. Sutherland 698Dialysable thyroxine-Effect of diazepam (Valium)on . . . V. F. Saldanha, R. Bird and C. W. R.Havard 329

Dialysis-Prevention of hepatitis in . . . units ...

S. Polakoff 501Dialysis-Psychiatric disturbance in chronic renal

failure and its treatment by . . . J. DonovanHailstone 549

Diazepam-Effect of . . . (Valium) on dialysablethyroxine . . . V. F. Saldhana, R. Bird andC. W. H. Havard 329

Diet low in calcium-Metacarpal bone dimensionsin young and aged South African Bantu con-suming a diet ... Alexander R. P. Walker, B. F.Walker and B. D. Richardson 320

Dietary factors in heart disease . .. I. Macdonald 33Dietary sugar intake of businessmen: the results ofa cross-sectional survey, The ... J. F. Richardson 423

Diets-Plasma lipids in obese children treated with350 Kcal diets ... Audrey S. Fosbrook, C. D. G.Brook and June K. Lloyd 444

Dimensions-metacarpal bone . . . in young andaged South African Bantu consuming a diet lowin calcium . . . Alexander R. P. Walker, B. F.Walker and B. D. Richardson 320

Disc-The results of surgery for low back and legpain due to presumptive, prolapsed interverte-bral ... G. E. Dunkerley 120

Disorders-Haemocytic periodicity and periodic: Periodic neutropenia, thrombocytopenia,

Lymphocytosis and anaemia . . . Hobart A.Reimann 504

Diuretics-The long-term treatment of hypertensionwith thiazide . . . D. G. Beevers, M. Hamiltonand J. E. Harpur 639

Diuretics-The use of amiloride hydrochloride inthe correction of hypokalaemic alkalosis inducedby... A. C. Anticliff, D. G. Beevers, M. Hamil-ton and J. E. Harpur 644

Double glucagon test, the-a new liver functiontest . . . H. Verhaegen, A. de Beukelaer, M. L.Verhaegen-Declerq and F. Krug 108

Drug addicts-Viral hepatitis in ... Susan F. Sull-man and A. J. Zuckerman 473

Drug resistance-Problems of ... in tuberculosis-the newer anti-tuberculosis drugs . . . JohnCrofton 748

Drug therapy-Laboratory aspects of intermittent... D. A. Mitchison and Jean M. Dickinson 737

Drug therapy, intermittent-General considerationsin ... of pulmonary tuberculosis ... Wallace Fox 729

Drugs, anti-arthritic-Gastric ulcer and the . . .

J. H. Emmanuel and R. D. Montgomery 227Drugs, anti-tuberculosis-Problems of drug resis-

tance in tuberculosis, the newer. . . John Crofton 748Duogastrone-induced hypokalaemic nephropathyand myopathy with myoglobinuria . .. A. B. S.Mitchell 807

Dyspepsia-Gallstones and flatulent ... : cause orcoincidence? ... Alan G. Johnson 767

Early insulin response-The pattern of . .. to oralglucose ... B. Karamanos, W. J. H. Butterfield,A. C. Asmal, B. D. Cox and M. J. Wichelow 440

Effect of diazepam (Valium) on dialysable thyroxine... V. F. Saldanha, R. Bird and C. W. H. Havard 329

Effect of surgical operation on leg venous flowmeasured with radioactive hippuran, the . . .

J. V. Harvey Kemble 773Electrocardiogram - Multiple unusual abnorma-

lities in the . .. in myxoedema . .. J. de Swiet 626Electron microscopic observations and speculationson Australia antigen ... June D. Almeida 484

Embolism-Mitral valve disease, systemic . .. andanticoagulants ... H. A. Fleming and Sheila M.Bailey 599

Embolism, pulmonary-The diagnosis of.. . Areview with particular reference to the use ofradionuclides . . . David J. Cook and HarryLander 214

Endogenous insulin-The peripheral uptake ofglucose and ... A. C. Asmal, W. J. H. Butterfield,B. D. Cox, B. Karamanos and M. J. Whichelow 407

England and Wales-Tuberculosis in. . . in the.next20 years ... J. R. Bignall 759

Epidemiology-Some aspects of the . .. of Hepa-titis in Sweden ... Olof Ringertz 465

Essential hypertension-Accessory artery in . . .

Boon Seng Ooi, Beatrice T. M. Cheng, ShengFong Yu and Oon Teik Khoo 197

Excretion-Blood acid/base studies and urinaryacid ... in obese fasting patients ... S. K. Ross,R. E. G. Dale, W. S. T. Thomson and J. T. Ire-land 447

Experimental approaches to the prophylaxis andtreatment of ischaemic heart disease . . . J. D.Fitzgerald 36

Extra-pyramidal disorders-Amantadine hydro-chloride and L-Dopa in .. . J. D. Parkes, R. P.Knill-Jones and P. J. Clements 116

Eyes, diabetics'-Forty years looking at . . . T. H.Whittington 62

Factors controlling the flux of glucose through thepentose phosphate pathway . . . Khalid A.Gumaa and Patricia McLean 403

Factors influencing the prognosis in myelomatosis... Audrey A. Dawson and D. Ogston 635

Familial periodic paralysis-Waardenburg's syn-drome and ... C. H. Tay 354

Fasting as a treatment of obesity ... T. Lawlor andD. G. Wells 452

Fasting-Blood acid/base studies and urinary acidexcretion in obese . . . patients . . . S. K. Ross,R. E. G. Dale, W. S. T. Thomson and J. T. Ireland 447

Fetal response to glucose loading ... R. W. Beard,R. C. Turner and N. W. Oakley 68

Fibrillation-Syncope in myxoedema due to tran-sient ventricular . . . Michael B. Macaulay andRobert J. Shepherd 361

Fibrinogen-Lipoprotein and . . . studies in dia-betes ... A. Hart, J. M. Thorp and H. Cohen 435

Index to Volume 47 vii

Fibrosa-Normocalcaemic primary hyperparathy-roidism with osteitis ... D. A. Heath and M. R.Wills 815

Fibrosing alveolitis and active chronic hepatitiswithout hyperglobulinaemia . . . R. B. Huddyand A. Ahmed 363

Fibrosis-Clindamycin levels in sputum in apatient with purulent chest disease due to cysticfibrosis ... J. A. Raeburn and J. D. Devine 366

Fibrosis-Idiopathic retroperitoneal . . . L. R.Pathak, R. C. Renjhen and C. P. Chandra 675

Flatulent dyspepsia-Gallstones and ... : cause orcoincidence?. . . Alan G. Johnson 767

Flux-Factors controlling the . . . of glucosethrough the pentose phosphate pathway . . .

Khalid A. Gumaa and Patricia McLean 403Fructose in medicine . . . Jussi K. Huttunen 654Frusemide-Clinical experience with metolazone in

fifty-two African patients; synergy with ... R. F.Gunstone, A. J. Wing, H. G. P. Shani, D. Njemoand E. M. W. Sabuka 789

Fusiform aneurysms of the brachial artery in a childtreated by proximal ligation . . . J. F. Colin andHarold Ellis 323

Gallstones and flatulent dyspepsia: cause or coinci-dence? ... Alan G. Johnson 767

Gangrene-Limb salvage arterial surgery for . . .

G. W. Taylor 251Gastrectomy, partial-Hypoglycaemic coma after

... P. A. Bacon and A. B. Myles 134Gastric-Carcinoma of the. . . antrum in identical

twins ... Frank I. Lee 622Gastric ulcer and the anti-arthritic drugs . . . J. H.Emmanuel and R. D. Montgomery 227

General considerations in intermittent drug therapyof pulmonary tuberculosis ... Wallace Fox 729

'General professional training' inquiry, A ... A. D.Clayden, J. Knowelden and James Parkhouse 201

Glucagon test, The double, a new liver functiontest . . . H. Verhaegen, A. de Beukelaer, M. L.Verhaegen-Declercq and F. Krug 108

Glucose-Factors controlling the flux of . . .

through the pentose phosphate pathway . . .

Khalid A. Gumaa and Patricia McLean 403Glucose-The insulin response to . . in patients

with non-diabetic glycosuria . . . M. T. McKiddie,R. T. A. Scott and R. Cole 605

Glucose-Intravenous ... tolerance in myocardialinfarction ... Donald Pearson 648

Glucose loading-Fetal response to . . . R. W.Beard, R. C. Turner and N. W. Oakley 68

Glucose-The pattern of early insulin response tooral ... B. Karamanos, W. J. H. Butterfield, A. C.Asmal, B. D. Cox and M. J. Wichelow 440

Glucose-The peripheral uptake of ... and endo-genous insulin ... A. C. Asmal, W. J. H. Butter-field, B. D. Cox, B. Karamanos and M. J.Wichelow 407

Glycosuria-The insulin response to glucose inpatients with non-diabetic ... M. T. McKiddie,R. T. A. Scott and R. Cole. 605

Guillain-Barre-Inappropriate secretion of anti-diuretic hormone in . syndrome ... Aeron G.Davies 651

Haematuria during methicillin therapy . . . P. J.Gallagher and D. J. Wayne 511

Haemochromatosis and diabetes . . . I. W. Dymockand Roger Williams 79

Haemocytic periodicity and periodic disorders:Periodic neutropenia, thrombocytopenia, lym-phocytosis and anaemia ... Hobart A. Reimann 504

Haemodialysis-associated hepatitis ... Ronald Finn 499Haemodialysis in the treatment of lactic acidosis

associated with acute hepatic and renal failure... A. Colombi and H. Tholen 628

Haemolytic anaemia, acquired, during the earlypuerperium-A case of . . . T. Singh 156

Headache-Psychological aspects of . . . P. K.Bridges 556

Heart block-Complete . .. in patients with pero-neal muscular atrophy ... B. A. J. Ponder, K.Chatterjee and G. C. Sutton 595

Heart disease-Dietary factors in ... I. Macdonald 33Heart disease-Non-cardiac morphological stig-mata in congenital ... Brian Livesley 800

Hepatic-Haemodialysis in the treatment of lacticacidosis associated with acute . . . and renalfailure ... A. Colombi and H. Tholen 628

Hepatic amoebiasis-Radiological changes in ... S.Ramachandran, D. L. N. Jayawardena andJ. R. A. Perumal 615

Hepatic-The management of acute ... failure ...Sheila Sherlock and S. P. Parbhoo 493

Hepatitis-Active chronic . . . and haemolyticanaemia associated with Rh-specific antibodies... C. D. R. Pengelly and R. C. Jennings 683

Hepatitis and activity ... Dennis M. Krikler 490Hepatitis-Haemodialysis-associated . . . RonaldFinn 499

Hepatitis-Infectious . . . in Bristol, 1959-70 ...J. F. Skone 462

Hepatitis-The multiple aetiology of viral ... A. J.Zuckerman 476

Hepatitis-Prevention of ... in dialysis units . . . S.Polakoff 501

Hepatitis-Prevention of ... with immunoglobulin... Daniel Reid 488

Hepatitis-Some aspects of the epidemiology of...in Sweden ... Olof Ringertz 465

Hepatitis-Viral ... in drug addicts ... Susan F.Sullman and A. J. Zuckerman 473

Hepatitis-Myocardial involvement in infectious... N. Nagaratnam, D. P. K. M. de Silva andK. R. W. Gunawardene 785

viii Postgraduate- Medical Journal

High-dose-Potentially serious side-effects of . . .

twice-weekly rifampicin ... Graham Poole, PeterStradling and Sheila Worlledge 742

Hilar-Mediastinoscopy: a diagnostic procedure in. . . and paratracheal lymphadenopathy ... J. R.

-.Mikhail, D. N. Mitchell and I. Sutherland 698Hippuran-The effect of surgical operation on legvenous flow measured with radioactive ... J. V.Harvey Kemble 773

Histiocytic-Splenectomy for ... medullary reticu-losis ... John M. Goldman, Bernard M. Jacob-son and G. Watson James III 671

Holt-Oram syndrome in a Maltese family ... F. F.Fenech, C. J. Jaccarani and P. Vassallo Agius 589

Hunger-Insulin, blood sugar and ... Trevor Silver-stone and Michael Besser 427

Hydrochloric acid-Metabolic alkalosis treatedwith intravenous . . . F. X. M. Beach and E.Sherwood Jones' 516

Hyperglobulinaemia-Fibrosing alveolitis andactive chronic hepatitis without. . . R. B. Huddyand A. Ahmed 363

Hyperosmolar-A critical appraisal of mechanismsconcerned in non-ketotic . . diabetic coma ...W. P. U. Jackson 399

Hyperosmolar non-ketotic diabetes ... Michael B.Macaulay 191

Hyperparathyroidism - Normocalcaemic primary... with osteitis fibrosa ... D. A. Heath andM. R. Wills 815

Hypertension, essential-Accessory artery in . . .

Boon Seng Ooi, Beatrice T. M. Cheng, ShengFong Yu and Oon Teik Khoo 197

Hypertension-The long-term treatment of... withthiazide diuretics ... D. G. Beevers, M. Hamiltonand J. E. Harpur 639

Hypertension-Psychosomatic aspects of . . .

Bernard Heine 541Hyperthyroid-Comparison of propanolol andLB 46 (prinodolol) on ... tachycardia ... A. G.Arbab and P. Turner 329

Hypnosis-An appraisal of ... H. Merskey ... 572Hypoglycaemic action of'metformin, the ... K. N.

Frayn, P. I. Adnitt and Paul Turner 777Hypoglycaemic coma after partial gastrectomy ...

P. A. Bacon and A. B. Myles 134Hypokalaemic myopathy and myoglobinuria due to

carbenoxolone sodium'. . . P. C. Barnes andJ. H. C. Leonard 813

Hypokalaemic nephropathy-Duogastrone induced... and myopathy with myoglobinuria ... A. B. S.Mitchell 807

Hypokalaemic-The use ofamiloride hydrochloridein the correction of . . . alkalosis induced bydiuretics ... A. C. Antcliff, D. G. Beevers, M.Hamilton and J. E. Harpur 644

Hyponatraemia-Cerebral oedema associated with... in renal failure ... K. K. Arora, M. J. Brum-mitt, Joanna Sheldon and J. A. P. Trafford 365

Hypothyroidism-Diabetes mellitus and . .. J. F.Bridgman 781

Hypothyroidism-The musculo-skeletal featuresof ... Douglas N. Golding 611

Identical twins-Carcinoma of the gastric antrumin ... Frank I. Lee 622

Idiopathic retroperitoneal fibrosis ... L. R. Pathak,R. C. Renjhen C. P. Chandra 675

Immunoglobulin-Prevention of hepatitis with ...Daniel Reid 488

Immunological aspects of asthma, the . . . H. E.Amos 166

Immunological studies on Burkitt's Lymphoma... George Klein 141

Imperfecta, osteogenesis,-. . . in a child presentingwith neurological features ... N. A. P. Evans 512

Inappropriate secretion of antidiuretic hormone inGuillain-Barre syndrome ... Aeron G. Davies 651

Inadequacy-Sexual ... in the male ... John Ban-croft 562

Incidence of obesity-A survey of the ... in theUnited Kingdom ... V. M. E. Montegriffo 418

Infarction-Intravenous glucose tolerance in myo-cardial ... Donald Pearson 648

Infarction-Myocardial . . . during pregnancy:report of two cases with a review of the literature... M. H. Husaini 660

Infectious diseases-Annual review of significantpublications ... Hobart A. Reimann 332

Infectious hepatitis in Bristol, 1959-70 . . . J. F.Skone 462

Infectious hepatitis-Myocardial involvement in... N. Nagaratnam, D. P. K. M. de Silva andK. R. W. Gunawardene 785

Injuries-Arterial ... and their management ...G. Slaney and F. Ashton 257

Inquiry-A 'general professional training' ... A. D.Clayden, J. Knowelden and James Parkhouse 201

Insulin, blood sugar and hunger ... Trevor Silver-stone and Michael Besser 427

Insulin-The peripheral uptake of glucose andendogenous ... A. C. Asmal, W. J. M. Butter-field, B. D. Cox, B. Karamanos and M. J.Wichelow 407

Insulin response to glucose in patients with non-diabetic glycosuria, the . . . M. T. McKiddie,R. T. A. Scott and R. Cole 605

Insulin response-The pattern of early ... to oralglucose ... B. Karamanos, W. J. H. Butterfield,A. C. Asmal, B. D. Cox and M. J. Wichelow 440

Insulin-The secretion of ... K. W. Taylor 57Insulin secretion rate in obesity, the ... Esko A.

Nikkila and Marja-Riitta Taskinen 412Intake, sugar-The dietary . . . of businessmen:The results of a cross-sectional survey . . . J. F.Richardson 423

Intermittent drug therapy-General considerationsin ... of pulmonary tuberculosis ... Wallace Fox 729

Intermittent drug therapy-Laboratory aspects of... D. A. Mitchison and Jean M. Dickinson 737

Intervertebral disc-The results of surgery for lowback and leg pain due to presumptive prolapsed... G. E. Dunkerley 120

Index to Volume 47 ix

Intravenous glucose tolerance in myocardial in-farction ... Donald Pearson 648

Intravenous-Metabolic alkalosis treated with ...hydrochloric acid . . . F. X. M. Beach and E.Sherwood Jones 516

Intracranial aneurysms-Use of an anti-fibrino-lytic agent (tranexamic acid) in the managementof ruptured ... J. R. Gibbs and A. G. L. Corkill 199

Involvement, myocardial, in infectious hepatitis ...N. Nagaratnam, D. P. K. M. de Silva andK. R. W. Gunawardene 785

Iodine-Raised serum protein-bound . . . aftertopical clioquinol . . . A. C. Upjohn, H-J. B.Galbraith and Bethel Solomons 515

Ischaemic heart disease-Experimental approachesto the prophylaxis and treatment of . . . J. D.Fitzgerald 36

Kcal, 350-Plasma lipids in obese children treatedwith ... diets ... Audrey S. Fosbrook, C. D. G.Brook and June K. Lloyd 444

Keto-acidotic, non- . . . diabetic coma ... J. V.Collins and P. W. R. Harris 388

Ketone bodies-Physiological ketosis, or why ... ?.. . D. H. Williamson 371

Ketosis-Physiological ... , or why ketone bodies?... D. H. Williamson 371

Ketotic, non- -A critical appraisal of mechanismsconcerned in ... hyperosmolar diabetic coma ...W. P. U. Jackson 399

Kidney-Secondary amyloidosis in relation to car-cinoma of the ... David Spencer 820

Kidney transplant failures-Presensitization and... P. I. Terasaki and M. Kreisler 89

Laboratory aspects of intermittent drug therapy ...D. A. Mitchison and Jean M. Dickinson 737

Lactic acidosis-Haemodialysis in the treatment of. . . associated with acute hepatic and renalfailure ... A. Colombi and H. Tholen 628

Lavage-Bronchial ... in asthma ... Norton E.Williams 188

L-Dopa and amantadine hydrochloride in extra-pyramidal disorders ... J. D. Parkes, R. P. Knill-Jones and P. J. Clements 116

Left atrial myxoma in a child diagnosed by ultra-sound ... A. J. S. Nicholls, M. A. Goodman andR. B. Pridie 804

Leg pain due to presumptive prolapsed inter-vertebral disc-The results of surgery for lowback and ... G. E. Dunkerley 120

Leg venous flow-The effect of surgical ooerationon ... measured with radioactive hippuran ...J. V. Harvey Kemble 773

Levels in sputum-Clindamycin . . . in a patientwith purulent chest disease due to cystic fibrosis... J. A. Raeburn and J. D. Devine 366

Ligation-Fusiform aneurysms of the brachialartery in a child treated by proximal ... J. F.Colin and Harold Eliis 323

Limb salvage arterial surgery for gangrene-G. W.Taylor 251

Lipids-Plasma ... in obese children treated with350 Kcal diets ... Audrey S. Fosbrooke, C. D. G.Brook and June K. Lloyd 444

Lipoma, a massive, in a patient receiving chlor-propamide therapy ... Henry A. Garfinkel 137

Lipoprotein and fibrinogen studies in diabetes ...A. Hart, J. M. Thorp and H. Cohen 435

Liver function test, a new-The double glucagontest ... H. Veraegen, A. de Beukelaer, M. L.Verhaegen Declercq and F. Krug 108

Long-term treatment of hypertension with thiazidediuretics-the ... D. G. Beevers, M. Hamiltonand J. E. Harpur 639

Lymphadenopathy-Mediastinoscopy: a diagnosticprocedure in hilar and paratracheal . . . J. R.Mikhail, D. N. Mitchell and I. Sutherland 698

Lymphadenopathy-Tuberculous cervical ... J. F.Newcombe 713

Lymphocytosis - Haemocytic periodicity andperiodic disorders: Periodic neutropenia, throm-bocytopenia, . . . , and anaemia ... Hobart A.Reimann 504

Lymphoma, -Burkitt's, -Immunological studieson ... George Klein 141

Male Sexual inadequacy in the ... John Bancroft 562Maltese family-Holt-Oram syndrome in a ... F. F,

Fenech, C. J. Jaccarani and P. Vassallo Agius' 589Management ofacute hepatic failure-the ... Sheila

Sherlock and S. P. Parbhoo 493Massive lipoma in a patient receiving chlorprop-amide therapy, a ... Henry A. Garfinkle 137

Mechanisms-A critical appraisal of . . . concernedin non-ketotic hyperosmolar diabetic coma . . .

W. P. U. Jackson 399Mediastinoscopy: a diagnostic procedure in hilarand paratracheal lymphadenopathy . . . J. R.Mikhail, D. N. Mitchell and I. Sutherland 698

Medicine-Fructose in ... Jussi K. Huttunen 654Medullary-Sp!enectomy for histiocytic ... reticu-

losis ... John M. Goldman, Bernard M. Jacobsonand G. Watson James III 671

Mellitus, diabetes-. and hypothyroidism ...J. F. Bridgman 781

Men, women and diabetes ... D. A. Pyke 54Mental symptoms-Some . . . in neurology . . .

Simon Behrman 101Metabolic alkalosis treated with intravenous hydro-

chloric acid ... F. X. M. Beach and E. SherwoodJones 516

Metacarpal bone dimensions in young and agedSouth African Bantu consuming a diet low incalcium ... Alexander R. P. Walker, B. F. Walkerand B. D. Richardson 3-20

Metformin-The hypoglycaemic action of... K. N.Frayn, P. I. Adnitt and Paul Turner 777

x Postgraduate Medical Journal

Methicillin-Haematuria during .. . therapy ...P. J. Gallagher and D. J. Wayne 511

Metolazone-Clinical experience with ... in fifty-two African patients: synergy with frusemide ...R. F. Gunstone, A. J. Wing, H. G. P. Shani, D.Njemo and E. M. W. Sabuka 789

Microscopic-Electron ... observations and specu-lations on Australia antigen ... June D. Almeida 484

Mites-Asthma and ... A. W. Frankland 178Mitral valve disease, systemic embolism and anti-

coagulants . . . H. A. Fleming and Sheila M.Bailey 599

Mood, nutrition and sleep: a study of patients withanorexia nervosa-The relationship between ...A. H. Crisp, Edward Stonehill and George W.Fenton 207

Morphological-Non-cardiac ... stigmata of con-genital heart disease . .. Brian Livesley 800

Multiple adenomatosis presenting with psychiatricmanifestations ... M. W. P. Carney, I. Weinbren,F. Jackson and G. V. Purnell 242

Multiple aetiology of viral hepatitis-the . .. A. J.Zuckerman 476

Multiple unusual abnormalities in the electro-cardiogram in myxoedema ... J. de Swiet 626

Muscular atrophy-Complete heart block inpatients with peroneal . . . B. A. J. Ponder, K.Chatterjee and G. C. Sutton 595

Musculo-skeletal features of hypothyroidism, the... Douglas N. Golding 611

Mycobacteria-The opportunist . . -a 20-yearretrospect ... J. Marks and P. A. Jenkins 705

Myelomatosis-Factors influencing the prognosisin ... Audrey A. Dawson and D. Ogston 635

Myocardial infarction during pregnancy: report oftwo cases with a review of the literature ... M. H.Husaini 660

Myocardial infarction-Intravenous glucose toler-ance in ... Donald Pearson 648

Myocardial infacrtion ... pacing after ... A. Harris 16Myocardial involvement in infectious hepatitis ...N. Nagaratnam, D. P. K. M. de Silva andK. R. W. Gunawardene 785

Myoglobinuria-Duogastrone-induced hypoka-laemic nephropathy and myopathy with . . .

A. B. S. Mitchell 807Myoglobinuria-Hypokalaemic myopathy and ...due to carbenoxolone sodium. . P. C. Barnesand J. H. C. Leonard 813

Myopathy- Duogastrone - induced hypokalaemicnephropathy and . . . with myoglobinuria . . .

A. B. S. Mitchell 807Myopathy-Hypokalaemic ... and myoglobinuriadue to carbenoxolone sodium . . . P. C. Barnesand J. H. C. Leonard 813

Myxoedema-Multiple unusual abnormalities inthe electrocardiogram in ... J. de Swiet 626

Myxoedema-Syncope in . . . due to transientventricular fibrillation . . . Michael B. Macaulayand Robert J. Shepherd 361

Myxoma-Left atrial ... in a child diagnosed byultra-sound ... A. J. S. Nichols, M. A. Goodmanand R. P. Pridie 804

Nephropathy, hypokalaemic - Duogastrone - in-duced ... and myopathy with myoglobinuria ...A. B. S. Mitchell 807

Neurological-Osteogenesis imperfecta in a childpresenting with ... features ... N. A. P. Evans 512

Neurology-Some mental symptoms in ... SimonBehrman 101

Neutropenia-Haemocytic periodicity and periodicdisorders: Periodic . . . , thrombocytopenia,lymphocytosis and anaemia . . . Hobart A.Reiman 504

Newer anti-tuberculosis drugs, the-Problems ofdrug resistance in tuberculosis ... John Crofton 748

Non-cardiac morphological stigmata of congenitalheart disease . .. Brian Livesley 800

Non-diabetic glycosuria-The insulin response toglucose in patients with . . . M. T. McKiddie,R. T. A. Scott and R. Cole 605

Non-keto-acidotic diabetic coma ... J. V. Collinsand P. W. R. Harris 388

Non-ketotic-A critical appraisal of mechanismsconcerned in ... hyperosmolar diabetic coma ...W. P. U. Jackson 399

Non-ketotic diabetes, hyperosmolar ... Michael B.Macaulay 191

Normocalcaemic primary hyperparathyroidism withosteitis fibrosa ... D. A. Heath and M. R. Wills 815

Nutrition, mood and sleep: a study of patients withanorexia nervosa-The relationship between . . .

A. H. Crisp, Edward Stonehill and George W.Fenton 207

Obese children-Plasma lipids in . . . treated with350 Kcal diets ... Audrey S. Fosbrooke, C. D. G.Brook and June K. Lloyd 444

Obese fasting patients-Blood acid/base studiesand urinary acid excretion in . . . S. K. Ross,R. E. G. Dale, W. S. T. Thomson and J. T.Ireland 447

Obesity-Fasting as a treatment of ... T. Lawlorand D. G. Wells 452

Obesity and coronary heart disease ... I. McLeanBaird 30

Obesity with cardio-respiratory failure ... P. Dinda,W. D. Riding and S. S. Chatterjee 158

Obesity and diabetes ... Arnold Bloom 430Obesity-The insulin secretion rate in ... Esko A.

Nikkila and Marja-Riitta Taskiners 412Obesity-A survey of the incidence of . .. in the

United Kingdom ... V. M. E. Montegriffo 418Oedema-Cerebral .. . associated with hyponatrae-mia in renal failure ... K. K. Arora, M. J. Brum-mitt, Joanna Sheldon and J. A. P. Trafford 365

Oliguric renal failure-Phaeochromocytoma of theurinary bladder with acute . . . : the use of aplasma catecholamine assay in diagnosis . . .

M. J. Goggin, J. Finberg, A. R. Adamson andA. M. Joekes 238

Operation, surgical-The effect of... on leg venousflow measured with radioactive hippuran . .. J. V.Harvey Kemble 773

Index to Volume 47 xi

Opportunist mycobacteria, the-a 20-year retro-spect ... J. Marks and P. A. Jenkins 705

Oral glucose-The pattern of early insulin responseto . . . B. Karamanos, W. J. H. Butterfield, A. C.Asmal, B. D. Cox and M. J. Whichelow 440

Osteitis fibrosa-Normocalcaemic primary hyper-parathyroidism with ... D. A. Heath and M. R.Wills 815

Osteogenesis imperfecta in a child presenting withneurological features .. . N. A. P. Evans 512

Osteomalacia, axial ... John R. Condon and J. R.Nassim 817

Osteomalacia following vagotomy and pyloroplasty... A. B. S. Mitchell, D. Glass and A. MortonGill 233

Pacing after myocardial infarction . . . A. Harris 16Paralysis-Waardenburg's syndrome and familial

periodic ... C. H. Tay 354Paratracheallymphadenopathy-Mediastinoscopy:a diagnostic procedure in hilar and . . . J. R.Mikhail, D. N. Mitchell and I. Sutherland 698

Parkinsonism-Current concepts of... John Pearceand Iris Pearce 794

Pathway-Factors controlling the flux of glucosethrough the pentose phosphate . . . Khalid A.Gumaa and Patricia McLean 403

Patient monitoring-Some aspects of continuous... H. S. Wolff 12

Pattern of early insulin response to oral glucose,the ... B. Karamanos, W. J. H. Butterfield, A. C.Asmal, B. D. Cox and M. J. Wichelow 440

Pentose phosphate-Factors controlling and fluxof glucose through the. . . pathway ... Khalid A.Gumaa and Patricia McLean 403

Pericarditis-Amoebic ... B. C. Bansal and D. S.Gupta 678

Periodic disorders-Haemocytic periodicity and: Periodic neutropenia, thrombocytopenia,

lymphocytosis and anaemia . . . Hobart A.Reimann 504

Periodic neutropenia-Haemocytic periodicity andperiodic disorders: . . . , thrombocytopenia,lymphocytosis and anaemia . . . Hobart A.Reimann 504

Periodic paralysis-Waardenburgs's syndrome andfamilial ... C. H. Tay 354

Periodicity-Haemocytic... and periodic disorders:Period c neutropenia, thrombocytopenia, lym-phocytosis and anaemia ... Hobart A. Reimann 504

Peripheral uptake of glucose and endogenous in-sulin, the . .. A. C. Asmal, W. J. H. Butterfield,B. D. Cox, B. Karamanos and M. J. Wichelow 407

Peroneal-Complete heart block in patients with... muscular atrophy ... B. A. J. Ponder, K.Chatterjee and G. C. Sutton 595

Phaeochromocytoma of the urinary bladder withacute oliguric renal failure: the use of a plasmacatecholamine assay in diagnosis . . . M. J.Goggin, J. Finberg, A. R. Adamson and A. M.Joekes 238

Phosphate-Factors controlling the flux of glucosethrough the pentose ... pathway ... Khalid A.Gumaa and Patricia McLean 403

Physiological ketosis, or why ketone bodies? . . .

D. H. Williamson 371Physiology and management of childhood asthma,

the ... R. S. Jones 181Plasma catecholamine assay-Phaeochromocytoma

of the urinary bladder with acute oliguric renalfailure: the use of a . . . in diagnosis . . . M. J.Goggin, J. Finberg, A. R. Adamson and A. M.Joekes 238

Plasma lipids in obese children treated with 350Kcal diets . . . Audrey S. Fosbrook, C. D. G.Brook and June K. Lloyd 444

Pneumatic rupture of colon ... Raj Kumar, T. R.Rowe and R. B. Dave 631

Policy-Future ... for BCG vaccination in Britain... Ian Sutherland 756

Postgraduate teaching hospital-Psychiatry in a ...David Abrahamson 538

Pregnancy-Diabetes mellitus and . . . (abstract)... J. Pederson 66

Pregnancy-Myocardial infarction during . . .:report of two cases with a review of the literature... M. H. Husaini 660

Presensitization and kidney transplant failures . . .P. I. Terasaki and M. Kreisler 89

Present position-A review of the . . . in Australiaantigen ... F. 0. MacCallum 481

Prevention of hepatitis in dialysis units . . . S.Polakoff 501

Prevention of hepatitis with immunog!obulin ...Daniel Reid 488

Primary hyperparathyroidism - Normocalcaemic... with osteitis fibrosa ... D. A. Heath andM. R. Wills 815

Primary sclerosing cholangitis . . . LaurenceTinckler 666

Prinodolol-Comparison of propanolol and LB 46(.. . ) on hyperthyroid tachycardia ... A. G.Arbab and P. Turner 329

Problems of drug resistance in tuberculosis-thenewer antituberculosis drugs ... John Crofton 748

Procedure-Mediastinoscopy: a diagnostic ... inhilar and paratracheal lymphadenopathy . . .

J. R. Mikhail, D. N. Mitchell and I. Sutherland 698'Professional training' inquiry-A 'general'. . . A. D.

Clayden, J. Knowelden and James Parkhouse 201Prognosis-Factors influencing the ... in myeloma-

tosis ... Audrey A. Dawson and D. Ogston 635Propanolol-Comparison of ... and LB 46 (prino-

dolol) on hyperthyroid tachycardia . . . A. G.Arbab and P. Turner 329

Prophylaxis, the-Experimental approaches to . . .and treatment of ischaemic heart disease . . .

J. D. Fitzgerald 36Protein-bound-Raised serum . . . iodine after

topical clioquinol . . . A. C. Upjohn, H-J. B.Galbraith and Bethel Solomons 515

Proximal ligation-Fusiform aneurysms of thebrachial artery in a child treated by . . . J. F.Colin and Harold Ellis 323

xii Postgraduate Medical Journal

Psychiatric disturbance in chronic renal failure andits treatment by dialysis ... J. Donovan Hailstone 549

Psychiatric manifestations-Multiple adenomatosispresenting with . . . M. W. P. Carney, I. Wein-bren, F. Jackson and G. V. Purnell 242

Psychiatrist, the-Reasons against referral to . . .

Alex G. Mezey and John M. Kellett 315Psychiatry in a postgraduate teaching hospital ...David Abrahamson 583

Psychological aspects of headache ... P. K. Bridges 556Psychological factors in asthma: a review of their

aetiological and therapeutic significance . . .

Samuel I. Cohen 533Psychosomatic aspects of hypertension ... BernardHeine 541

Psychosomatic-Basic . . . concepts . . . Heinz H.Wolfe 525

Puerperium, the early-A case of acquired haemo-lytic anaemia during ... T. Singh 156

Pulmonary embolism-The diagnosis of... a reviewwith particular reference to the use of radio-nuclides ... David J. Cook and Harry Lander 214

Pulmonary tuberculosis-General considerations inintermittent drug therapy of ... Wallace Fox 729

Purulent chest disease-Clindamycin levels insputum in a patient with . .. due to cystic fibrosis. . . J. A. Raeburn and J. D. Devine 366

Pyloroplasty-Osteomalacia following vagotomyand ... A. B. S. Mitchell, D. Glass and A. MortonGill 233

Radioactive hippuran-The effect of surgical opera-tion on leg venous flow measured with . .. J. V.Kemble 773

Radiological changes in hepatic amoebiasis . .. S.Ramachandran, D. L. N. Jayawardena andJ. R. A. Perumal 615

Radionuclides-The diagnosis of pumonary em-bolism: a review with particular reference to theuse of . .. David J. Cook and Harry Lander 214

Raised serum protein-bound iodine after topicalclioquinol . . . A. C. Upjohn, H-J. B. Galbraithand Bethel Solomons 515

Raynaud-The ... syndrome ... Martin Birnstingl 297Reasons against referral to the psychiatrist ... AlexG. Mezey and John M. Kellett 315

Referral to the psychiatrist-Reasons against ...Alex G. Mezey and John M. Kellett 315

Relationship between sleep, nutrition and mood: astudy of patients with anorexia nervosa ... A. H.Crisp, Edward Stonehill and George W. Fenton 207

Renal failure-Cerebral oedema associated withhyponatraemia in ... K. K. Arora, M. J. Brum-mitt, Joanna Sheldon and J. A. P. Trafford 365

Renal failure-Haemodialysis in the treatment oflactic acidosis associated with acute hepatic andrenal failure ... A. Colombi and H. Tholen 628

Renal failure-Phaeochromocytoma of the urinarybladder with acute oliguric . . . : the use of aplasma catecholamine assay in diagnosis . . .

M. J. Goggin, J. Finberg, A. R. Adamson andA. M. Joekes 238

Renal-Psychiatric disturbance in chronic . . .

failure and its treatment by dialysis. . . J. Dono-van Hailstone 549

Resistance, drug-Problems of... in tuberculosis-the newer anti-tuberculosis drugs . . . JohnCrofton 748

Resistance patterns of urinary tract pathogens ingeneral practice-A six-year survey of ... M. H.Robertson 111

Response to glucose-The insulin . . . in patientswith non-diabetic glycosuria ... M. T. McKiddie,R. T. A. Scott and R. Cole 605

Response-The pattern of early insulin . .. to oralglucose ... B. Karamanos, W. J. H. Butterfield,A. C. Asmal, B. D. Cox and M. J. Whichelow 440

Results of surgery for low back and leg pain due topresumptive prolapsed intervertebral disc, the. . .G. E. Dunkerley 120

Reticulosis-Splenectomy for histiocytic medullary. . . John M. Goldman, Bernard M. Jacobsonand G. Watson James III 671

Retroperitoneal-Idiopathic ... fibrosis ... L. R.Pathak, R. C. Renjhen and C. P. Chandra 675

Rh-specific-Active chronic hepatitis and haemo-lytic anaemia associated with ... antibodies . . .C. D. R. Pengelly and R. C. Jennings 683

Rheology of sputum in asthma-Biochemistry and... E. E. Keal 171

Rifampicin-Potentially serious side-effects ofhigh-dose twice-weekly ... Graham Poole, PeterStradling and Sheila Worlledge 742

Rupture-Pneumatic ... of colon ... Raj Kumar,T. R. Rowe and R. B. Dave 631

Ruptured intracranial aneurysms-Use of an anti-fibrinolytic agent (tranexamic acid) in themanagement of . . . J. R. Gibbs and A. G. L.Corkill 199

Salvage-Limb . . . arterial surgery for gangrene ...G. W. Taylor 251

Sclerosing-Primary ... cholangitis ... LaurenceTinckler 666

Secondary amyloidosis in relation to carcinoma ofthe kidney ... David Spencer 820

Secretion-Inappropriate . . . of antidiuretic hor-mone in Guillain-Barre syndrome ... Aeron G.Davies 651

Secretion of insulin, the ... K. W. Taylor 57Secretion, insulin-The ... rate in obesity ... EskoA. Nikkila and Marja-Riitta Taskinen 412

Self-poisoning with colchicine . . . M. G. Ellwoodand G. H. Robb 129

Sensitivity-Tuberculin ... in tuberculosis ... J. G.Scadding 694

Serum-Raised . . . protein-bound iodine aftertopical clioquinol ... A. C. Upjohn, H-J. B. Gal-braith and Bethel Solomons 515

Sexual inadequacy in the male ... John Bancroft 562Side-effects-Potentially serious . .- . of high-dose

twice-weekly rifampicin ... Graham Poole, PeterStradling and Sheila Worlledge 742

Index to Volume 47 xiii

Six-year survey of resistance patterns of urinarytract pathogens in general practice, a . .. M. H.Robertson 111

Skeletal-Musculo-... features of hypothyroidism,the ... Douglas N. Golding 611

Sleep, nutrition and mood: a study of patients withanorexia nervosa-The relationship between ...A. H. Crisp, Edward Stonehill and George W.Fenton 207

Sodium-Hypokalaemic myopathy and myoglo-binuria due to carbenoxolone ... P. C. Barnesand J. H. C. Leonard 813

Some mental symptoms in neurology . . . SimonBehrman 101

South African Bantu consuming a diet low in cal-cium-Metacarpal bone dimensions in youngand aged . . . Alexander R. P. Walker, B. F.Walker and B. D. Richardson 320

Spinal cord-Subacute combined degeneration ofthe . . . in a vegan . . . H. N. Misra and J. M.Fallowfield 624

Spinal tuberculosis-J. W. Jackson 723Splenectomy for histiocytic medullary reticulosis

... John M. Goldman, Bernard M. Jacobson andG. Watson James III 671

Sprue-Temperate . . . M. J. Kendall and T. J.Bayley 680

Sputum in asthma-Biochemistry and rheology of... E. E. Keal 171

Sputum-Clindamycin levels in ... in a patient withpurvulent chest disease due to cystic fibrosis ...J. A. Raeburn and J. D. Devine 366

Stigmata-non-cardiac morphological . . . of con-genital heart disease . .. Brian Livesley 800

Studies-Blood acid/base . .. and urinary acid ex-cretion in obese fasting patients . . . S. K. Ross,R. E. G. Dale, W. S. T. Thomson and J. T. Ire-land 447

Studies in diabetes-Lipoprotein and fibrinogen ...A. Hart, J. M. Thorp and H. Cohen 435

Subacute combined degeneration of the spinal cordin a vegan ... H. N. Misra and J. M. Fallowfield 624

Sugar-Insulin, blood ... and hunger ... TrevorSilverstone and Michael Besser 427

Sugar intake-The dietary ... of businessmen: theresults of a cross-sectional survey . . . J. F.Richardson 423

Surgery for low back and leg pain due to presump-tive prolapsed intervertebral disc-The results of... G. E. Dunkerley 120

Surgery-Limb salvage artetial ... for gangrene ...G. W. Taylor 251

Surgery-Vascular ... comes of age ... H. H. G.Eastcott 250

Surgical aspects of carotid-vertebral insufficiency... J. A. Gillespie 282

Surgical operation-The effect of ... on leg venousflow measured with radioactive hippuran ... J. V.Harvey Kemble 773

Survey-The dietary sugar intake of businessmen:the results of a cross-sectional ... J. F. Richardson 423

Survey of the incidence of obesity in the UnitedKingdom ... V. M. E. Montegriffo 418

Sweden-Some aspects of the epidemiology ofhepatitis in . . . Olof Ringertz 465

Syncope in myxoedema due to transient ventricularfibrillation ... Michael B. Macaulay and RobertJ. Shepherd 361

Syndrome-Holt-Oram ... in a Maltese family ...F. F. Fenech, C. J. Jaccarani and P. VassalloAgius 589

Syndrome-Guillain-Barre-Inappropriate secre-tion of antidiuretic hormone in . . . Aeron G.Davies 651

Syndrome-The Raynaud ... Martin Birnstingl 297Synergy-Clinical experience with metolazone in

fifty-two African patients: .. . with frusemide ...R. F. Gunstone, A. J. Wing, H. G. P. Shani, D.Njemo and E. M. W. Sabuka 789

Systemic embolism-Mitral valve disease . . . andanticoagulants ... H. A. Fleming and Sheila M.Bailey 599

Tachycardia-Comparison of propanolol andLB 46 (prinodolol) on hyperthyroid . . . A. G.Arbab and P. Turner 329

Teaching hospital-Psychiatry in a postgraduate... David Abrahamson 538

Temperate sprue . . . M. J. Kendall and T. J.Bayley 680

Tension pneumoperitoneum as a post-operativecomplication of multiple abdominal injuries ...D. Keown and K. Cronin 131

Therapeutic-Psychological factors in asthma: areview of their aetiological and . . . significance... Samuel I. Cohen 533

Therapy, chloropropamide-A massive lipoma ina patient receiving . .. Henry A. Garfinkel 137

Therapy, drug-Laboratory aspects of intermittent-... D. A. Mitchison and Jean M. Dickinson 737

Therapy-General considerations in intermittentdrug ... of pulmonary tuberculosis . .. WallaceFox 729

Therapy-Haematuria during methicillin ... P. J.Gallagher and D. J. Wayne 511

Thiazide-The long-term treatment of hypertensionwith . . . diuretics . . . D. G. Beevers, M. Hamil-ton and J. E. Harpur 639

Thrombocytopenia-Haemocytic periodicity andperiodic disorders: Periodic neutropenia .lymphocytosis and anaemia . . . Hobart A.Reimann -504

Thrombosis-Deep vein ... G. E. Mavor 311Thyroid-Aplastic anaemia with carcinoma of the

... C. C. Smith and A. J. King 161Thyroxine-Effect of diazepam (Valium) on dialys-

able . . . V. F. Saldanha, R. Bird and C. W. H. GHavard 329

Tolerance-Intravenous glucose . . . in myocardialinfarction ... Donald Pearson 648

Topical clioquinol-Raised serum protein-boundiodine after . . . A. C. Upjohn, H-J. B. Gal-braith and Bethel Solomons 515

xiv Postgraduate Medical Journal

Tranexamic acid-Use of an anti-fibrinolytic agent(... ) in the management of ruptured intracranialaneurysms ... J. R. Gibbs and A. G. L. Corkill 199

Transient ventricular fibrillation-Syncope inmyxoedema due to ... Michael B. Macaulay andRobert J. Shepherd 361

Treatment of obesity-Fasting as a . .. T. Lawlorand D. G. Wells 452

Tuberculosis in Brent... M. W. McNicol and J. R.Mikhail 691

Tuberculosis in England and Wales in the next 20years . .. J. R. Bignall 759

Tuberculosis-Problems of drug resistance in ...the newer anti-tuberculosis drugs . . . JohnCrofton 748

Tuberculosis, pulmonary-General considerationsin intermittent drug therapy of . .. Wallace Fox 729

Tuberculosis-Tuberculin sensitivity in . . . J. G.Scadding 694

Tuberculosis, spinal ... J. W. Jackson 723Tuberculosis, urinary .. . P. R. Riddle 718Tuberculin sensitivity in tuberculosis . . . J. G.

Scadding 694Tuberculous cervical lymphadenopathy-J. F.Newcombe 713

Twice-weekly-Potentially serious side-effects ofhigh-dose ... rifampicin ... Graham Poole, PeterStradling and Sheila Worlledge 742

Twins-Carcinoma of the gastric antrum in identi-cal . . . Frank I. Lee 622

Ulcer-gastric-and the anti-arthritic drugs . . .

J. H. Emmanuel and R. D. Montgomery 227Ultra-sound-Left atrial myxoma of a child diag-nosed by ... A. J. S. Nicholls, M. A. Goodmanand R. B. Pridie 804

Uncontrolled-Acetone in ... diabetes ... M. J.Sulway, M. D. Trotter, E. Trotter and J. M.Malins 382

United Kingdom, the-A survey of the incidence ofobesity in the ... V. M. E. Montegriffo 418

Unusual abnormalities-Multiple ... in the electro-cardiogram in myxoedema ... J. de Swiet 626

Uptake of glucose-The peripheral . .. and endo-genous insulin ... A. C. Asmal, W. J. H. Butter-field, B. D. Cox, B. Karamanos and M. J.Wichelow 407

Urinary bladder, the-Phaeochromocytoma of... with acute oliguric renal failure: the use of aplasma catecholamine assay in diagnosis . . .

M. J. Goggin, J. Finberg, A. R. Adamson andA. M. Joekes 238

Urinary-Blood acid/base studies and . . . acidexcretion in obese fasting patients ... S. K. Ross,R. E. G. Dale, W. S. T. Thomson and J. T.Ireland 447

Urinary tract pathogens-A six-year survey ofresistance patterns of . .. in general practice ...

M. H. Robertson 111Urinary tuberculosis . .. P. R. Riddle 718

Vaccination, BCG-Future policy for ... in Britain... Ian Sutherland 756

Vagotomy-Osteomalacia following ... and pyloro-plasty . . . A. B. S. Mitchell, D. Glass and A.Morton Gill 233

(Valium)-Effect of diazepam (... ) on dialysablethyroxine . . . V. F. Saldanha, R. Bird andC. W. H. Havard 329

Valve disease, mitral, systemic embolism and anti-coagulants . . . H. A. Fleming and Sheila M.Bailey 599

Vascular surgery comes of age-Introduction ...H. H. G. Eastcott 250

Vascular surgery-Diabetes and . .. L. T. Cotton,D. I. R. Higton and H. E. Berry 84

Vegan-Subacute combined degeneration of thespinal cord in a ... H. N. Misra and J. M. Fallow-field 624

Vein-Deep ... thrombosis ... G. E. Mavor 311Venous flow-Effect of surgical operation on leg

... measured with radioactive hippuran ... J. V.Harvey Kemble 773

Ventricular fibrillation-Syncope in myxoedemadue to transient . . . Michael B. Macaulay andRobert J. Shepherd 361

Viral hepatitis in drug addicts. . . Susan F. Sullmanand A. J. Zuckerman 473

Viral hepatitis-The multiple aetiology of ... A. J.Zuckerman 473

Waardenburg's syndrome and familial periodicparalysis ... C. H. Tay 354

Wales-Tuberculosis in England and ... in the next20 years ... J. R. Bignall 759

Years, the next 20-Tuberculosis in England andWales in . . . J. R. Bignall 759

Young and aged South African Bantu consuming adiet low in calcium-Metacarpal bone dimen-sions in ... Alexander R. P. Walker, B. F. Walker,and B. D. Richardson 320

Author Index

Abrahamson, David: Psychiatry in a postgraduateteaching hospital 538

Adamson, A.R. (and Goggin, M.J., Finberg, J. andJoekes, A.M.): Phaeochromocytoma of theurinary bladder with acute oliguric renal failure:the use of a plasma catecholamine assay indiagnosis 238

Adnitt, P.I. (Frayn, K.N. and Turner, Paul): Thehypoglycaemic action of metformin 777

Agius, P. Vassallo (Fenech, F.F. and Jaccarani,C.J.): Holt-Oram syndrome in a Maltese family 589

Ahmed, A. (and Huddy, R.B.): Fibrosing alveolitisand active chronic hepatitis without hyper-globinaemia 363

Almeida, June D.: Electron microscopic observa-tions and speculations on Australia antigen 484

Amos, H. E.: The immunological aspects of asthma 166Antcliff, A.C. (and Beevers, D.G., Hamilton, M.and Harpur, J.E.): The use of amiloride hydro-chloride in the correction of hypokalaemic alka-losis induced by diuretics 644

Arbab, A.G. (and Turner, P.): Comparison ofpropanolol and LB 46 (prinodolol) on hyper-thyroid tachycardia 329

Arora, K.K. (Brummitt, M.J., Sheldon, Joanna andTrafford, J.A.P.): Cerebral oedema associatedwith hyponatraemia in renal failure 365

Ashton, F. (and Slaney, G.): Arterial injuries andtheir management 257

Asmal, A.C. (Butterfield, W.J.H., Cox, B.D.,Karamanos, B. and Whichelow, M.J.): The peri-pheral uptake of glucose and endogenous insulin 407

Asmal, A.C. (Karamanos, B., Butterfield, W.J.H.,Cox, B.D. and Whichelow, M.J.): The pattern ofearly insulin response to oral glucose 440

Bacon, P.A. (and Myles, A.B.): Hypoglycaemiccoma after partial gastrectomy 134

Bailey, Sheila M. (and Fleming, H.A.): Mitralvalve disease, systemic embolism and anticoagu-lants 599

Bancroft, John: Sexual inadequacy in the male 562Bansal, B.C. (and Gupta, D.S.): Amoebic peri-

carditis 678Barnes, P.C. (and Leonard, J.H.C.): Hypokalaemicmyopathy and myoglobinuria due to carbenoxo-lone sodium 813

Bayley, T.J. (and Kendall, M.J.): Temperate sprue 680Beach, F.X.M. (and Jones, E. Sherwood): Meta-

bolic alkalosis treated with intravenous hydro-chloric acid 516

Beard, R.W. (and Turner, R.C. and Oakley, N.W.):Fetal response to glucose loading 68

Beevers, D.G. (and Antcliff, A.C., Hamilton, M.and Harpur, J.E.): The use of amiloride hydro-chloride in the correction of hypokalaemicalkalosis induced by diuretics 644

Beevers, D.G. (and Hamilton, M. and Harpur, J.E.):The long-term treatment of hypertension withthiazide diuretics 639

Behrman, Simon: Some mental symptoms inneurology 101

Berry, H.E. (and Cotton, L.T. and Higton, D.I.R.):Diabetes and vascular surgery 84

Besser, Michael (and Silverstone, Trevor): Insulin,blood sugar and hunger 427

Bignall, J.R.: Tuberculosis in England and Walesin the next 20 years 759

Bird, R. (Saldanha, V.F. and Havard, C.W.H.):Effect of diazepam (Valium) on dialysablethyroxine 329

Birnstingl, Martin: The Raynaud syndrome 297Bloom, Arnold: Obesity and diabetes 430Bridges, P.K.: Psychological aspects of headache 556Bridgman, J.F.: Diabetes mellitus and hypo-

thyroidism 781Brook, C.D.G. (Fosbrook, Audrey, S. and Lloyd,

June K.): Plasma lipids in obese children treatedwith 350 Kcal diets 444

Brummit, M.J. (and Arora, K.K., Sheldon, Joannaand Trafford, J.A.P.): Cerebral oedema associ-ated with hyponatraemia in renal failure 365

Butterfield, W.J.M. (and Asmal, A.C., Cox, B.D.,Karamanos, B. and Whichelow, M.J.): Theperipheral uptake of glucose and endogenousinsulin 407

Butterfield, W.J.H. (and Karamanos, B., Asmal,A.C., Cox, B.D. and Whichelow, M.J.): Thepattern of early insulin response to oral glucose 440

Carney, M.W.P. (Weinbren, I, Jackson, F. andPurnell, G.V.): Multiple adenomatosis presentingwith psychiatric manifestations 242

Chandra, C.P. (Pathak, L.R. and Renjhen, R.C.):Idiopathic retroperitoneal fibrosis 675

Chatterjee, K. (Ponder, B.A.J. and Sutton, G.C.):Complete heart block in patients with peronealmuscular atrophy 595

Chatterjee, S.S. (Dinda, P. and Riding, W.D.):Obesity with cardio-respiratory failure 158

Chen, Beatrice T.M. (Ooi, Boon Seng, Yu, ShenFong and Khoo, Oon Teik): The accessory arteryin essential hypertension 197

Clayden, A.D. (Knowelden, J. and Parkhouse,James): A 'general professional training' inquiry 201

Clements, P.J. (Parkes, J.D. and Knill-Jones, R.P.):L-Dopa and amantidine hydrochloride in extra-pyramidal disorders 116

Cohen, H. (Hart, A. and Thorp, J.M.): Lipopro-tein and fibrinogen studies in diabetes 435

Cohen, Samuel I.: Psychological factors in asthma:a review of their aetiological and therapeuticsignificance 533

xvi Postgraduate Medical Journal

Cole, R. (McKiddie, M.T. and Scott, R.T.A.): Theinsulin response to glucose in patients with non-diabetic glycosuria 605

Colin, J.F. (and Ellis, Harold): Fusiform aneurysmsof the brachial artery in a child treated by proxi-mal ligation 323

Collins, J.V. (and Harris, P.W.R.): Non-keto-acidotic diabetic coma 388

Colombi, A. (and Tholen, H.): Haemodialysis inthe treatment of lactic acidosis associated withacute hepatic and renal failure 628

Condon, John R. (and Nassim, J.R.): Axial osteo-malacia 817

Cook,David J. (and Lander, Harry): The diagnosisof pulmonary embolism: a review with particularreference to the use of radionuclides 214

Corkill, A.G.L. (and Gibbs, J.R.): Use of an anti-fibrinolytic agent (tranexamic acid) in the manage-ment of ruptured intracranial aneurysms 199

Cotton, L.T. (and Higton, D.I.R. and Berry, H.E.)Diabetes and vascular surgery 84

Cox, B.D. (and Asmal, A.C., Butterfield, W.J.M.,Karamanos, B. and Whichelow, M.J.): The peri-pheral uptake of glucose and endogenous insulin 407

Cox, B.D. (and Karamanos, B., Butterfield, W.J.H.,Asmal, A.C. and Whichelow, M.J.): The patternof early insulin response to oral glucose 440

Crisp, A.H. (Stonehill, Edward and Fenton, GeorgeW.): The relationship between sleep, nutritionand mood: a study of patients with anorexianervosa 207

Crofton, John: Problems of drug resistance intuberculosis-the newer anti-tuberculosis drugs 748

Cronin, K. (and Keown, D.): Tension pneumoperi-toneum as a post-operative complication ofmultiple abdominal injuries 131

Dale, R.E.G. (Ross, S.K., Thomson, W.S.T. andIreland, J.T.): Blood acid/base studies andurinary acid excretion in obese fasting patients 447

Dave, R.B. (Kumar, Raj and Rowe, T.R.): Pneu-matic rupture of colon 631

Davies, Aeron G.: Inappropriate secretion of anti-diuretic hormone in Guillain-Barre syndrome 651

Dawson, Audrey A. (and Ogston, D.): Factors in-fluencing the prognosis in myelomatosis 635

De Beukelaer, A. (Verhaegen-Declerq, M.L.,Verhaegen, H. and Krug, F.): The double gluca-gon test, a new liver function test 108

De Silva, D.P.K.M. (and Nagaratnam, N. andGunawardene, K.R.W.): Myocardial involve-ment in infectious hepatitis 785

De Swiet, J.: Multiple unusual abnormalities in theelectrocardiogram in myxoedema 626

Devine, J.D. (and Raeburn, J.A.): Clindamycinlevels in sputum in a patient with purulent chestdisease due to cystic fibrosis 366

Dickinson, Jean M. (and Mitchison, D.A.): Labora-tory aspects of intermittent drug therapy 737

Dinda, P. (Riding, W.D. and Chatterjee, S.S.):Obesity with cardio-respiratory failure 158

Dunkerley, G.E.: The results of surgery for lowback and leg pain due to presumptive prolapsedintervertebral disc 120

Dymock, I.W. (and Roger Williams): Haemochro-matosis and diabetes 79

Eastcott, H.H.G.: Vascular surgery comes of age 250Ellis, Harold (and Colin, J.F.): Fusiform aneurysms

of the brachial artery in a child treated by proxi-mal ligation 323

Ellwood, M.G. (and Robb, G.H.): Self-poisoningwith colchicine 129

Emmanuel, J.H. (and Montgomery, R.D.): Gastriculcer and the anti-arthritic drugs 227

Evans, N.A.P.: Osteogenesis imperfecta in a childpresenting with neurological features 512

Fallowfield, J.M. (and Misra, H.N.): Subacutecombined degeneration of the spinal cord in avegan 624

Fenech, F.F. (Jaccarani, C.J. and Agius, P.Vassallo): Holt-Oram syndrome in a Maltesefamily 589

Fenton, George W. (Crisp, A.H. and Stonehill,Edward): The relationship between sleep, nutri-tion and mood: a study of patients with anorexianervosa 207

Finberg, J. (Goggin, M.J., Adamson, A.R. andJoekes, A.M.): Phaeochromocytoma of theurinary bladder with acute oliguric renal failure;the use of a plasma catecholamine assay indiagnosis 238

Finn, Ronald: Haemodialysis-associated hepatitis 499Fitzgerald, J.D.: Experimental approaches to the

prophylaxis and treatment of ischaemic heartdisease 36

Fleming, H.A. (and Bailey, Sheila, M.): Mitral valvedisease, systemic embolism and anticoagulants 599

Fosbrook, Audrey S. (and Brook, C.D.G. andLloyd, June K.): Plasma lipids in obese childrentreated with 350 Kcal diets 444

Fox, Wallace: General considerations in inter-mittent drug therapy of pulmonary tuberculosis 729

Frankland, A.W.: Asthma and mites 178Frayn, K.N. (Adnitt, P.I. and Turner, Paul): The

hypoglycaemic action of metformin 777

Galbraith, H-J. B. (Upjohn, A.C. and Solomons,Bethel): Raised serum protein-bound iodine aftertopical clioquinol 515

Gallagher, P.J. (and Wayne, D.J.): Haematuriaduring methicillin therapy 511

Garfinkel, Henry A.: A massive lipoma in a patientreceiving chlorpropamide therapy 137

Gibbs, J.R. (and Corkill, A.G.L.): Use of an anti-fibrinolytic agent (tranexamic acid) in themanagement of ruptured intracranial aneurysms 199

Index to Volume 47 xvii

Gill, A. Morton (Mitchill, A.B.S. and Glass, D.):Osteomalacia following vagotomy and pyloro-plasty 233

Gillespie, J.A.: Surgical aspects of carotid-vertebralinsufficiency 282

Glass, D. (Mitchell, A.B.S. and Gill, A. Morton):Osteomalacia following vagotomy and pyloro-plasty 233

Goggin, M.J. (Finberg, J., Adamson, A.R. andJoekes, A.M.): Phaeochromocytoma of theurinary bladder with acute oliguric renal failure:the use of a plasma catecholamine assay indiagnosis 238

Golding, Douglas N.: The musculo-skeletalfeatures of hypothyroidism 611

Goldman, John M. (Jacobson, Bernard M. andJames III, G. Watson): Splenectomy for his-tiocytic medullary reticulosis 671

Goodman, M.A. (Nicholls, A.J.S. and Pridie, R.B.):Left atrial myxoma in a child diagnosed by ultra-sound 804

Gumaa, Khalid A. (and McLean, Patricia): Factorscontrolling the flux ofglucose through the pentosephosphate pathway 403

Gunawardene, K.R.W. (Nagaratnam, N. and deSilva, D.P.K.M.): Myocardial involvement ininfectious hepatitis 785

Gunstone, R.F. (Wing, A.J., Shani, H.G.P., Njemo,D. and Sabuka, E.M.W.): Clinical experience withmetolazone in fifty-two African patients: synergywith frusemide 789

Gupta, D.S. (and Bansal, B.C.): Amoebic pericar-ditis 678

Hailstone, J. Donovan: Psychiatric disturbance inchronic renal failure and its treatment by di-alysis 549

Hamilton, M. (Antcliff, A.C., Beevers, D.G. andHarpur, J.E.): The use of amiloride hydro-chloride in the correction of hypokalaemicalkalosis induced by diuretics 644

Hamilton, M. (Beevers, D.G. and Harpur, J.E.):The long-term treatment of hypertension withthiazide diuretics 639

Harpur, J.E. (Antcliff, A.C., Beevers, D.G. andHamilton, M.): The use of amiloride hydro-chloride in the correction of hypokalaemicalkalosis induced by diuretics 644

Harpur, J.E. (Beevers, D.G. and Hamilton, M.):The long-term treatment of hypertension withthiazide diuretics 639

Harris, A.: Pacing after myocardial infarction 16Harris, P.W.R. (and Collins, J.V.): Non-keto-

acidotic diabetic coma 388Hart, A. (Thorp, J.M. and Cohen, H.): Lipoproteinand fibrinogen studies in diabetes 435

Havard, C.W.H. (Saldanha, V.F. and Bird, R.):Effect of diazepam (Valium) on dialysablethyroxine 329

Heath, D.A. (and Wills, M.R.): Normocalcaemicprimary hyperparathyroidism with osteitisfibrosa 815

Heine, Bernard: Psychosomatic aspects of hyper-tension 541

Higton, D.I.R. (Cotton, L.T. and Berry, H.E.):Diabetes and vascular surgery 84

Hockaday, T.D.R.: Diabetic comas 376Huddy, R.B. (and Ahmed, A.): Fibrosing alveolitisand active chronic hepatitis without hyperglo-bulinaemia 363

Husaini, M.H.: Myocardial infarction during preg-nancy: report of two cases with a review of theliterature 660

Huttunen, Jussi K.: Fructose in medicine 654

Ireland, J.T. (Ross, S.K., Dale, R.E.G. and Thom-son, W.S.T.): Blood acid/base studies andurinary acid excretion in obese fasting patients 447

Jaccarani, C.J. (Fenech, F.F. and Agius, P.Vassallo): Holt-Oram syndrome in a Maltesefamily 589

Jackson, F. (Carney, M.W.P., Weinbren, I. andPurnell, G.V.): Multiple adenomatosis presentingwith psychiatric manifestations 242

Jackson, J.W.: Spinal tuberculosis 723Jackson, W.P.U.: A critical appraisal of mech-

anisms concerned in non-ketotic hyperosmolardiabetic coma 399

Jacobson, Bernard M. (Goldman, John M. andJames III, G. Watson): Splenectomy for his-tiocytic medullary reticulosis 671

James III, G. Watson (Goldman, John M. andJacobson, Bernard M.): Splenectomy for histio-cytic medullary reticulosis 671

Jayawardena, D.L.N. (Ramachandran, S. andPerumal, J.R.A.): Radiological changes inhepatic amoebiasis 615

Jenkins, P.A. (and Marks, J.): The opportunistmycobacteria-a 20-year retrospect 705

Jennings, R.C. (and Pengelly, C.D.R.): Activechronic hepatitis and haemolytic anaemia associ-ated with Rh-specific antibodies 683

Joekes, A.M. (Goggin, M.J., Finberg, J. andAdamson, A.R.): Phaeochromocytoma of theurinary bladder with acute oliguric renal failure:the use of a plasma catecholamine assay in diag-nosis 238

Johnson, Alan G.: Gallstones and flatulent dys-pepsia: cause or coincidence? 767

Jones, E. Sherwood (and Beach, F.X.M.): Meta-bolic alkalosis treated with intravenous hydro-chloric acid 516

Jones, R.S.: The physiology and management ofchildhood asthma 181

Karamanos, B. (Asmal, A.C., Butterfield, W.J.H.,Cox, B.D. and Whichelow, M.J.): The peripheraluptake of glucose and endogenous insulin 407

xviii Postgraduate Medical Journal

Karamanos, B. (Butterfield, W.J.H., Asmal, A.C.,Cox, B.D. and Whichelow, M.J.): The pattern ofearly insulin response to oral glucose 440

Keal, E.E.: Biochemistry and rheology of sputumin asthma 171

Kellett, John M. (and Mezey, Alex G.): Reasonsagainst referral to the psychiatrist 315

Kemble, J.V. Harvey: The effect of surgical opera-tion on leg venous flow measured with radio-active hippuran 773

Kendall, M.J. (and Bayley, T.J.): Temperate sprue 680Keown, D. (and Cronin, K.): Tension pneumoperi-toneum as a post-operative complication ofmultiple abdominal injuries 131

Khoo, Oon Teik (Ooi, Boon Seng, Chen, BeatriceT.M. and Yu, Sheng Fong): The accessory arteryin essential hypertension 197

King, A.J. (and Smith, C.C.): Aplastic anaemiawith carcinoma of the thyroid 161

Klein, George: Immunological studies on Burkitt'slymphoma 141

Knill-Jones, R.P. (Parkes, J.D. and Clements, P.J.):L-Dopa and amantadine hydrochloride in extrapyramidal disorders 116

Knowelden, J. (Clayden, A.D. and Parkhouse,James): A 'general professional training' inquiry 201

Kreisler, M. (and Terasaki, P.I.): Presensitizationand kidney transplant failures 89

Krikler, Dennis M.: Hepatitis and activity 490Krug, F. (Verhaegen, H., de Beukelaer, A. and

Verhaegen-Declercq, M.L.): The double glucagontest, a new liver function test 108

Kumar, Raj (Rowe, T.R. and Dave, R.B.): Pneu-matic rupture of colon 631

Lander, Harry (and Cook, David J.): The diagnosisof pulmonary embolism: a review with particularreference to the use of radionuclides 214

Lawlor, T. (and Wells, D.G.): Fasting as a treat-ment of obesity 452

Lee, Frank I.: Carcinoma of the gastric antrum inidentical twins 622

Leonard, J.H.C. (and Barnes, P.C.): Hypokalaemicmyopathy and myoglobinuria due to carbenozo-lone sodium 813

Livesley, Brian: Non-cardiac morphological stig-mata in congenital heart disease 800

Lloyd, June 'K. (Fosbrook, Audrey S. and Brook,C.D.G.): Plasma lipids in obese children treatedwith 350 Kcal diets 444

McAllen, P.M.: Experiences of intensive coronarycare in a regional hispital 5

McKiddie, M.T. (Scott, R.T.A. and Cole, R): Theinsulin response to glucose in patients with non-diabetic glycosuria 605

McLean, Patricia (and Gumaa, Khalid, A.):Factors controlling the flux of glucose throughthe pentose phosphate pathway 403

McLean, Baird I.: Obesity and coronary heartdisease 30

McNicol, M.W. (and Mikhail, J.R. and Sutherland,I.): Tuberculosis in Brent 691

Macaulay, Michael B.: Hyperosmolar non-ketoticdiabetes 191

Macaulay, Michael B. (and Shepherd, Robert J.):Syncope in myxoedema due to transient ventricu-lar fibrillation 361

MacCallum, F.O.: A review of the present positionof Australia antigen 481

Macdonald, I.: Dietary factors in heart disease 33Malins, M.J. (Sulway, M.J., Trotter, M.D. and

Trotter, E.): Acetone in uncontrolled diabetes 382Marks, J. (and Jenkins, P.A.): The opportunistmycobacteria-a 20-year retrospect 705

Mavor, G.E.: Deep vein thrombosis 311Mendelssohn, Elizabeth S.: Some nursing problems

in a coronary care unit 3Merskey, H.: An appraisal of hypnosis 572Mezey, Alex G. (and Kellett, John M.): Reasons

against referral to the psychiatrist 315Mikhail, J.R. (and McNicol, M.W. and Sutherland,

I): Tuberculosis in Brent 691Mikhail, J.R. (Mitchell, D.N. and Sutherland, I.):

Mediastinoscopy: A diagnostic procedure inhilar and paratracheal lymphadenopathy 698

Misra, H.N. (and Fallowfield, J.M.): Subacutecombined degeneration of the spinal cord in avegan 624

Mitchell, A.B.S.: Duogastrone-induced hypoka-leamic nephropathy and myopathy with myoglo-binuria 807

Mitchell, A.B.S. (Glass, D. and Morton Gill, A.):Osteomalacia following vagotomy and pyloro-plasty 233

Mitchell, D.N. (Mikhail, J.R. and Sutherland, I.):Mediastinoscopy: a diagnostic procedure inhilar and paratracheal lymphadenopathy 698

Mitchison, D.A. (and Dickinson, Jean M.): Labora-tory aspects of intermittent drug therapy 737

Montegriffo, V.M.E.: A survey of the incidence ofobesity in the United Kingdom 418

Montgomery, R.D. (and Emmanuel, J.H.): Gastriculcer and the anti-arthritic drugs 227

Myles, A.B. (and Bacon, P.A.): Hypoglycaemiccoma after partial gastrectomy 134

Nagaratnam, N. (de Silva, D.P.K.M. and Guna-wardene, K.R.W.): Myocardial involvement ininfectious hepatitis 785

Newcombe, J.F.: Tuberculous cervical lympha-denopathy 713

Nicholls, A.J.S. (Goodman, M.A. and Pridie, R.B.):Left atrial myxoma in a child diagnosed by ultra-sound 804

Nikkila, Esko A. (and Taskinen, Marja-Riitta):The insulin secretion rate in obesity 412

Njemo, D. (Gunstone, R.F., Wing, A.J., Shani,H.G.P. and Sabuka, E.M.W.): Clinical experi-ence with metolazone in fifty-two Africanpatients: synergy with frusemide 789

Index to Volume 47 xix

Oakley, N.W. (Beard, R.W. and Turner, R.C.):Fetal response to glucose loading 68

Oakley, W.G.: The management of diabetic comaover one-third of a century 48

Ogston, D. (and Dawson, Audrey A.): Factors in-fluencing the prognosis in myelomatosis 635

Ooi, Boon Seng (and Chen, Beatrice T.M., Yu,Sheng Fong and Khoo, Oon Teik): The accessoryartery in essential hypertension 197

Parbhoo, S.P. (and Sherlock, Sheila): The manage-ment of acute hepatic failure 493

Parkes, J.D. (Knill-Jones, R.P. and Clements, P.J.):L-Dopa and amantadine hydrochloride in extra-pyramidal disorders 116

Parkhouse, James (Clayden, A.D. and Knowelden,J.): A 'general professional training' inquiry 201

Pathak, L.R. (Renjhen, R.C. and Chandra, C.P.):Idiopathic retroperitoneal fibrosis 675

Pearce, Iris (and Pearce, John): Current conceptsof Parkinsonism 794

Pearce, John (and Pearce, Iris): Current conceptsof Parkinsonism 794

Pearson, Donald: Intravenous glucose tolerance inmyocardial infarction 648

Pederson, J.: Diabetes mellitus and pregnancy(abstract) 66

Pengelly, C.D.R. (and Jennings, R.C.): Activechronic hepatitis and haemolytic anaemia associ-ated with Rh-specific antibodies 683

Perumal, J.R.A. (Ramachandran, S. and Jayawar-dena, D.L.N.): Radiological changes in hepaticamoebiasis 615

Polakoff, S.: Prevention of hepatitis in dialysisunits 501

Ponder B.A.J. (and Chatterjee, K. and Sutton,G.C.): Complete heart block in patients withperoneal muscular atrophy 595

Poole, Graham (Stradling, Peter and Worlledge,Sheila): Potentially serious side-effects of high-dose twice-weekly rifampicin 742

Pridie, R.B. (Nicholls, A.J.S. and Goodman, M.A.):Left atrial myxoma in a child diagnosed by ultra-sound 804

Purnell, G.V. (Carney, M.W.P., Weinbren, I. andJackson, F.): Multiple adenomatosis presentingwith psychiatric manifestations 242

Pyke, D.A.: Men, women and diabetes 54

Raeburn, J.A. (and Devine, J.D.): Clindamycinlevels in sputum in a patient with purulent chestdisease due to cystic fibrosis 366

Ramachandran, S. (Jayawardena, D.L.N. andPerumal, J.R.A.): Radiological changes inhepatic amoebiasis 615

Reid, Daniel: Prevention of hepatitis with immuno-globulin 488

Reimann, Hobart A.: Infectious diseases: Annualreview of significant publications 332

Reimann, Hobart A.: Haemocytic periodicity andperiodic disorders: Periodic neutropenia, throm-bocytopenia, lymphocytosis and anaemia 504

Renjhen, R.C. (Pathak, L.R. and Chandra, C.P.):Idiopathic retroperitoneal fibrosis 675

Richardson, B.D. (Walter, Alexander, R.P. andWalker, B.F.): Metacarpal bone dimensions inyoung and aged South African Bantu consuminga diet low in calcium 320

Richardson, J.F.: The dietary sugar intake ofbusinessmen: the results of a cross-sectionalsurvey 423

Riddle, P.R.: Urinary tuberculosis 718Riding, W.D. (Dinda, P. and Chatterjee, S.S.):

Obesity with cardio-respiratory failure 158Ringertz, Olof: Some aspects of epidemiology of

hepatitis in Sweden 465Robb, G.H. (and Ellwood, M.G.): Self-poisoning

with colchicine 129Robertson, M.H.: A six-year survey of resistance

patterns of urinary tract pathogens in generalpractice 111

Ross, S.K. (Dale, R.E.G., Thomson, W.S.T. andIreland, J.T.): Blood acid/base studies andurinary acid excretion in obese fasting patients 447

Rowe, T.R. (Kumar, Raj and Dave, R.B.): Pneu-matic rupture of colon 631

Sabuka, E.M.W. (Gunstone, R.F., Wing, A.J.,Shani, H.G.P. and Njemo, D.): Clinical ex-perience with metolazone in fifty-two Africanpatients; synergy with frusemide 789

Saldanha, V.F. (Bird, R. and Havard, C.W.H.):Effect of diazepam (Valium) on dialysablethyroxine 329

Scadding, J.G.: Tuberculin sensitivity in tubercu-losis 694

Scott, R.T.A. (McKiddie, M.T. and Cole, R.):The insulin response to glucose in patients withnon-diabetic glycosuria 605

Shani, H.G.R. (Gunstone, R.F., Wing, A.J.,Njemo, D. and Sabuka, E.M.W.): Clinical ex-perience with metolazone in fifty-two Africanpatients; synergy with frusemide 789

Sheldon, Joanna (Arora, K.K., Brummitt, M.J. andTrafford, J.A.P.): Cerebral oedema associatedwith hyponatraemia in renal failure 365

Shepherd, Robert J. (and Macaulay, Michael B.):Syncope in myxoedema due to transient ventri-cular fibrillation 361

Sherlock, Sheila (and Parbhoo, S.P.): The manage-ment of acute hepatic failure 493

Shillingford, J.: A review of current and futuretrends in coronary care 23

Silverstone, Trevor (and Besser, Michael): Insulin,blood sugar and hunger 427

Singh, T.: A case of acquired haemolytic anaemiaduring the early puerperium 156

Skone J.F.: Infectious hepatitis in Bristol 1959-70 462Slaney, G. (and Ashton, F.): Arterial injuries and

their management 257

xx Postgraduate Medical Journal

Smith, C.C. (and King, A.J.): Aplastic anaemiawith carcinoma of the thyroid 161

Solomons, Bethel (Upjohn, A.C. and Galbraith,H-J. B.): Raised serum protein-bound iodineafter topical clioquinol 515

Spencer, David: Secondary amyloidosis in relationto carcinoma of the kidney 820

Stonehill, Edward (Crisp, A.H. and Fenton, GeorgeW.): The relationship between sleep, nutritionand mood; a study of patients with anorexianervosa 207

Stradling, Peter (Poole, Graham and Worlledge,Sheila): Potentially serious side-effects of high-dose twice-weekly rifampicin 742

Sullman, Susan F. (and Zuckerman, A.J.): Viralhepatitis in drug addicts 473

Sulway, M.J. (Trotter, M.D., Trotter, E. andMalins, J.M.): Acetone in uncontrolled diabetes 382

Sutherland, Ian: Future policy for BCG vaccina-tion in Britain . 756

Sutherland, I. (Mikhail, J.R. and McNicol, M.W.):Tubercolosis in Brent 691

Sutherland, I. (Mikhail, J.R. and Mitchell, D.N.):Mediastinoscopy: a diagnostic procedure in hilarand paratracheal lymphadenopathy 698

Sutton, G.C. (Ponder, B.A.J. and Chatterjee, K.):Complete heart block in patients with peronealmuscular atrophy 595

Taskinen, 'Marja-Riitta (and Nikkila, Esko A.):The insulin secretion rate in obesity 412

Tay, C.H.: Waardenburg's syndrome and familialperiodic paralysis 354

Taylor, G.W.: Limb salvage arterial surgery forgangrene 251

Taylor, K.W.: The secretion of insulin 57Terasaki, P.I. (and Kreisler, M.): Presensitizationand kidney transplant failures 89

Tholen,.H. (and Colombi, A.): Haemodialysis in thetreatment of lactic acidosis associated with acutehepatic and renal failure 628

Thomson, W.S.T. (Ross, S.K., Dale, R.E.G. andIreland, J.T.): Blood acid/base studies andurinary acid excretion in obese fasting patients 447

Thorp, J.M. (Hart, A. and Cohen, H.): Lipoproteinand fibrinogen studies in diabetes 435

Tibbs, David J.: Aneurysms 270Tinckler, Laurence: Primary sclerosing cholangitis 666Trafford, J.A.P. (Arora, K.K., Brummitt, M.J. and

Sheldon, Joanna): Cerebral oedema associatedwith hyponatraemia in renal failure 365

Trotter, E. (Sulway, M.J., Trotter, M.D. andMalins, J.M.): Acetone in uncontrolled diabetes 382

Trotter, M.D. (Sulway, M.J., Trotter, E. and MalinsJ.M.): Acetone in uncontrolled diabetes 382

Turner, P. (and Arbab, A.G.): Comparison of pro-panolol and LB 46 (prinodolol) on hyperthyroidtachycardia 329

Turner, Paul (Frayn, K.N. and Adnitt, P.I.): Thehypoglycaemic action of metformin .777

Turner, R.C. (Beard, R.W. and Oakley, N.W.):Fetal response to glucose loading 68

Upjohn, A.C. (Galbraith, H-J.B and Solomons,Bethel): Raised serum protein-bound iodine aftertopical clioquinol 515

Verhaegen, H. (de Beukelaer, A., Verhaegen-Declercq and Krug, F.): The double glucagontest, a new liver function test 108

Verhaegen-Declercq, M.L. (Verhaegen, H., deBeuklaer, A. and Krug, F.): The double glucagontest, a new liver function test 108

Walker, Alexander R.P. (Walker, B.F. andRichardson, B.D.): Metacarpal bone dimensionsin young and aged South African Bantu con-suming a diet low in calcium 320

Walker, B.F. (Walker, Alexander, R.P. andRichardson, B.D.): Metacarpal bone dimensionsin young and aged South African Bantu consum-ing a diet low in calcium 320

Wayne, D.J. (and Gallagher, P.J.): Haematuriaduring methicillin therapy 511

Weinbren, I. (Carney, M.W.P., Jackson, F. andPurnell, G.V.): Multiple adenomatosis present-ing with psychiatric manifestations 242

Wells, D.G. (and Lawlor, T.): Fasting as a treat-ment of obesity 452

Whichelow, M.J. (Karamanos, B., Butterfield,W.J.H., Asmal, A.C. and Cox, B.D.): Thepattern of early insulin response to oral glucose 440

Whichelow, M.J. (Asmal, A.C., Butterfield, W.J.H.,Cox, B.D. and Karamanos, B.): The peripheraluptake of glucose and endogenous insulin 407

Whittington, T.H.: Forty years looking at diabetics'eyes 62

Williams, Norton E.: Bronchial lavage in asthma 188Williams, Roger (and Dymock, I.W.): Haemochro-

matosis and diabetes 79Williamson, D.H.: Physiological ketosis, or why

ketone bodies? 371Wills, M.R. (and Heath, D.A.): Normocalcaemic

hyperparathyroidism with osteitis fibrosa 815Wing, A.J. (Gunstone, R.F., Shani, H.G.R.,Njemo, D. and Sabuka, E.M.W.): Clinicalexperience with metolazone in fifty-two Africanpatients: Synergy with frusemide 789

Wolff, Heinz H.: Basic psychosomatic concepts 525Wolff, H.S.: Some aspects of continuous patient

monitoring 12Worlledge, Sheila (Poole, Graham and Stradling,

Peter): Potentially serious side-effects of high-dose twice weekly rifampicin 742

t

Yu, Sheng Fong (Ooi, Boon Seng, Chen, Beatrice,T.M. and Khoo, Oon Teik): The accessoryartery in essential hypertension 197

Zuckerman, A.J.: The multiple aetiology of viralhepatitis 476

Zuckerman, A.J. (and Sullman, Susan F.): Viralhepatitis in drug addicts 473

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(10-' g) mg centimetre(s) cmmicrogram(s) millicurie(s) mCi

(104 g) t±g millilitre(s) mlnanogram(s) pound(s) lb

(l0"g) ng milliequivalent mEqpicogram(s)

(10-11 g) pg RF values RFhour(s) hrminute(s) min gravitational acceleration gmicron(s) I percent %

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