plan competition 2016 tomotherapy planning system plan competition... · additional contours...

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Radiotherapy Plan Competition 2016 TomoTherapy Planning System Dmytro Synchuk Ukrainian Center of TomoTherapy, Kirovograd, Ukraine

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Page 1: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Radiotherapy Plan Competition 2016

TomoTherapy Planning System

Dmytro Synchuk

Ukrainian Center of TomoTherapy,Kirovograd, Ukraine

Page 2: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Beam Geometry

• 6MV fan beam

• 3 jaw options 1.0, 2.5 and 5 cm

• 64 leaves binary collimator

• Leaf measurement at isocenter 0.65cm

Page 3: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Delivery regimes

HELICAL

• Continuous gantry rotation at a constant rate

• Continuous couch movement in superior direction

DIRECT

• Discrete 2-12 static directions

• Continuous couch movement in superior direction for each direction separately

Page 4: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Objective function

where

The smaller volume we can control the better

OARsTargetsPlan FFF

voxels

2

calcprescrROIvolumeROI

penaltyDVHpenaltiesdoseimportance)D(DF

Page 5: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Beam blocking

None(Default)

DirectionalBlocking

CompleteBlocking

Target

Critical Structure

Target

Critical Structure

Target

Critical Structure

Allowed Beam Direction

Prohibited Beam Direction

• Directional Blocking – only those beam directions that first go through the target are allowed

• Complete Blocking – all beam directions that go through the completely blocked structure are prohibited

Page 6: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

How I did my first Plan

Troubleshootings:

• Time cumbersome

• Works only for PTV_BREAST

• Steel needed additional structures

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121994/

Page 7: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Additional Contours

• Dmin1 – 0,5 cm margin around the PTV to create steep dose gradient around the target

• Dmin2 – 2,5-3 cm margin around the PTV to avoid high doses in body

Dmin2

Dmin1 Dmin1

Dmin2

Page 8: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Additional Contours

• Brest Right Block – 3 mm outer ring completely blocked to achieve no more than 2Gy dose inside right breast• HEART BLOCK – part of the hard that is further than 3 cm from PTV (completely blocked)• HEART Plan - part of the hard that is closer than 3 cm to PTV (here I optimize)• LUNG LEFT BLOCK – part of the left lung that is further than 3 cm from PTV (completely blocked)• Dmin Lung Left – part of the left lung that is closer than 1.5 cm to PTV• LUNG LEFT Plan – part of the left lung that is closer than 3 cm to PTV excluding Dmin Lung Left

Breast Right Block

LUNGRIGHTBLOCK

HEARTBLOCK

LUNGLEFTBLOCK

LUNG LEFT Plan

Page 9: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Additional contours

Emergence of PTV SC leads to:• LUNG LEFT Top – part of the left lung that is closer than 3 cm to PTV on the slices

where PTV SC is present• LUNG RIGHT BLOCK – part of the right lung that is 1.5 cm lover than PTV SC • Avoidances – some volumes where some “dose problems” are predicted or found

LUNGRIGHTBLOCK

LUNGRIGHT

LUNG LEFT Top

LUNG LEFT Top

LUNGRIGHT

Avoidances

Page 10: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Additional contours

• Block – structure in the inferior part of the body made as the prolongation of the blocked regions

• PTV Min – small part of the PTV made to shrink the volume of minimum dose

BLOCK

PTV Min

Page 11: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

General Parameters

• Calculation Grid Fine resolution equal to imported planning images (256x256)

• Field width 2.5 cm was set according to the PTV length

• Beamlet Mode is a general mode in clinical practice - optimizer uses pre-computed dose volumes and simply re-weightings them

widthfield

/rotationdPitch couch

beamletsusedfortimeopenbeamletAverage

timeopenbeamletMaxMF

Page 12: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

General Parameters

• Calculation Grid Fine resolution equal to imported planning images (256x256)

• Field width 2.5 cm was set according to the PTV length

• Beamlet Mode is a general mode in clinical practice - optimizer uses pre-computed dose volumes and simply re-weightings them

widthfield

/rotationdPitch couch

beamletsusedfortimeopenbeamletAverage

timeopenbeamletMaxMF

Page 13: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Starting restrictions

Page 14: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

First Results

• First I protect OARs

Page 15: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Further optimization

• Now I work with Targets

• Don’t forget about OARs

Page 16: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Further optimization

Page 17: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Final restrictions

Page 18: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Final Histogram

Full Dose Final Dose

Page 19: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Final Dose Distribution

Page 20: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Main difference from my first plan

Page 21: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Evaluation

Old Results New Results

Page 22: Plan Competition 2016 Tomotherapy Planning System Plan Competition... · Additional contours Emergence of PTV SC leads to: • LUNG LEFT Top –part of the left lung that is closer

Thank You!