physician flip chart
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Physician Flip Chart. The Egg Donation Process. Ottawa Fertility Centre. Topics to be discussed. Should I consider treatment with egg donation? Who are the egg donors? What are logistics between my cycle and my donor? What is recipient screening? What are the pregnancy rates? - PowerPoint PPT PresentationTRANSCRIPT
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PHYSICIAN FLIP CHART
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Ottawa Fertility Centre
The Egg Donation Process
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•Should I consider treatment with egg donation?
•Who are the egg donors?
•What are logistics between my cycle and my donor?
•What is recipient screening?
•What are the pregnancy rates?
•What are my financial options?
TOPICS TO BE DISCUSSED
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OPTIONS AVAILABLE
Ideal choice would be using your own egg and partner sperm
If the ideal option is not feasible the remaining options are:• Adoption • Donor Egg• Choosing Not to have Children
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WHEN IS EGG DONATION NEEDED?
Decreased Ovarian Function
Premature Ovarian Failure
Genetic Abnormalities
Failure of Other
Treatments
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GENETICS OF AGING OOCYTE
Maternal AgeChromosomal
AbnormalityNewborns
30 1/385
35 1/192
40 1/66
41 1/53
42 1/42
43 1/33
44 1/26
45 1/21Reproductive Medicine Associates: Genetics 2003-2004
ACOG publications
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EFFECTS OF AGE ON PREGNANCY RATES
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OOCYTE NUMBER
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DONOR SCREENING REQUIREMENTS
•Women between the ages of 21 – 32 years
•Height & Weight Proportionate (BMI <28)
•Non-smokers
•Healthy Medical and Family History
•Normal Hormone & Ovarian Evaluation
•Consultation with physician or nurse practitioner
• Negative drug screening
• Negative for Communicable Diseases, in accordance to FDA protocol
• Genetic Screening (Cystic Fibrosis, SMA, Fragile X and ethnically indicated genetic disorders)
• Psychological Evaluation
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Full profile includes :
• Physical characteristics
• Health and obstetrical history
• Family health history
• Likes & Interests
• Personal Essay Questions, including motivation for donation
• Childhood and adult photographs
DONOR APPLICATION
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REASONS FOR DONOR EXCLUSION
•Poor baseline hormone values and/or antral follicle count
•Psychological exclusion
•Problematic medical or family history
•Smoker
•Positive drug screen
•Positive genetic screen
•Donor changes mind, relocation, schedule conflict
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FDONOR EGG BANK USA
• Recipients receive 5-7 mature eggs• No need for synchronization with donor• Widens donor selection• No wait to select• More control of cycle timing• Less expensive
Advantages
• Limited number of eggs• Lower chance of embryo cryopreservation
Disadvantages
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SELECTING A DONOR
Decide on a donor program: fresh or frozen
View Donor Profiles
Select Donor
Make payment and start your cycle
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TIPS FOR SELECTING A DONOR
• Take your time, you may not see someone you like immediately
• Expect to match the most important issues
• Expect to make compromises on some less important issues
• Look for intellectual potential (essay and skills section), not just education level
• Everyone has imperfections
• Matching blood types is not medically necessary and does not impact success rates
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INFANT COMPLICATIONS FROM MULTIPLE PREGNANCY
Singleton Twin Triplet
Average Month at Birth 9 mths 8 mths 7 mths
% Very Premature(<7 mths) 1.7% 14% 41%
Average Birth Weight 7.4lbs 5.2lbs 3.8lbs
% Severe Handicap 1.9% 3.4% 5.7%
% Infant Mortality 0.6% 2.8% 19%
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DONOR EGG BANK USA THROUGH DECEMBER 31, 2013
EggThaws
EmbryosTransfers
Average # of Eggs
per Cycle
Average # of Embryos
Transferred
Clinical Pregnancies
(% ET) Miscarriages
(% ET)Ongoing
Pregnancies (% ET)
626 582 6.21.8
(day 3)1.6
(day 5)
291(50%)
36 (6%)
255(44%)