physical activity research: portfolio analysis · physical activity research: portfolio analysis...
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PHYSICAL ACTIVITY
RESEARCH: PORTFOLIO
ANALYSIS
Physical Activity Workshop: How do we get more people moving more?
December 14, 2012
Barry Portnoy
Jessica Wu
Office of Disease Prevention
National Institutes of Health
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What is Portfolio Analysis?
Purpose: To describe the distribution of projects and
research that NIH funds
Identify trends in funding
Aids strategic planning initiatives, budget analysis
QVR
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Purpose for PA Portfolio Analysis
To provide a preliminary, high-level overview of
NIH’s physical activity funding portfolio
To identify distribution of funding portfolio
Over time
Across ICs
Across different categories
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PA Portfolio Analysis: Overview
1. Search with QVR (Query/View/Report)
2. Develop validation rubric
3. Manually sort and validate grants
4. Identify challenges and limitations to understand
boundaries of the analysis
5. Analyze data
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PA Portfolio Analysis: Step 1
Search with QVR (Query, View, and Report)
Limited search to RCDC category “Prevention”
Searched FY2008-FY2011
Funded and Awarded NIH grants
Broad keyword search terms in title and abstracts of
grant applications: “Exercise” or “Physical Activity”
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Portfolio Analysis Process: Step 2
Validation Rubric: Used titles and abstracts
Did not include: Animal studies, tertiary prevention, meditation
Did include:
If “physical activity” or “exercise” was mentioned in the title or abstract
if PA was measured or included in questionnaire
physical inactivity/sedentary behavior
Large trials or studies that incorporated PA (Look AHEAD, Mr. OS)
Did not group grants into further categories
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Portfolio Analysis Process: Results
After manual validation…
Fiscal Year Number of
entries
Valid entries % Valid
entries
2011 1285 787 61%
2010 1537 876 57%
2009 1617 932 58%
2008 1314 817 62%
2008-2011 5753 3412 59%
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Challenges and Limitations
RCDC coding: Computerized reporting process
Tracking multi-year projects
Does not accurately reflect budget
Does not capture detailed information
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Challenges and Limitations, pt. 2
Implications for data analysis results:
Very rough overview of physical activity portfolio
Unknown sensitivity, high specificity
Qualitative rather than quantitative
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Budget
Fiscal Year
Physical Activity
Prevention (from RCDC)0
1000
2000
3000
4000
5000
6000
$ (
in M
illions)
20082009
20102011
NIH Prevention and Physical Activity Research Budget
Prevention budget (RCDC):
$5.5B/year
20% of total NIH budget
PA budget (on average): $340M/year
6% of Prevention budget
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PA Budget vs. RCDC Categories
Average Funding Per Year (FY2008-11)
$0
$100
$200
$300
$400
$500
$600
$700
$800
$900
Obesity Tobacco Chronic Pain Injury(Accidents/adverse
effects)
Physical Activity
Fundin
g (
$m
illions)
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Data Visualization Programs
NIH Topic Maps: Cluster-based visualization using
CSR Integrated Review Groups
IN-SPIRE: Text-mining and data visualization tool
NIH Portfolio Visualization Tool (Pviz)
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NIHMaps: 2011
Projects
Population Sciences
& Epidemiology
Surgical Sciences, Biomedical
Imaging, & Bioengineering
Risk Prevention &
Health Behavior
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NIHMaps: 2011
Projects
Population Sciences
& Epidemiology
Surgical Sciences, Biomedical
Imaging, & Bioengineering
Risk Prevention &
Health Behavior
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Risk Prevention &
Health Behavior
Population Sciences
& Epidemiology
NIHMaps: 2011
Validated Projects
Surgical Sciences, Biomedical
Imaging, & Bioengineering
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Projects by Year
0
100
200
300
400
500
600
700
800
900
1000
FY2008 FY2009 FY2010 FY2011
Other (FIC, NEI, NHGRI, NIAAA, NIAID,NIDCD, NIDCR, NIGMS, NLM)
NIEHS
NCCAM
NINDS
NCRR
NIDA
NIMH
NIAMS
NINR
NIMHD
NIA
NICHD
NCI
NIDDK
NHLBI
NICHD
NHLBI
NIDDK
NCI
# P
roje
cts
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Projects by Year
0
100
200
300
400
500
600
700
800
900
1000
FY2008 FY2009 FY2010 FY2011
Other (FIC, NEI, NHGRI, NIAAA, NIAID,NIDCD, NIDCR, NIGMS, NLM)
NIEHS
NCCAM
NINDS
NCRR
NIDA
NIMH
NIAMS
NINR
NIMHD
NIA
NICHD
NCI
NIDDK
NHLBI
NICHD
NHLBI
NCRR
NIDDK
NCI
# P
roje
cts
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Grant Activity Codes
F- Fellowship Programs
K- Research Career Programs
P- Research Program Projects and Centers
R- Research Projects
U- Cooperative Agreements
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Projects by Activity
0 500 1000 1500 2000 2500
F
Other
U
K
P
R (not R01)
R01
R (all)
FY08
FY09
FY10
FY11
# Projects
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Distribution by Funding Mechanism
R- Research Projects
R01 64%
R03 6%
R18 4%
R21 13%
R24 2% R (others)
11%
All other grants
R grants
R01: Research Project
R03: Small Research Grants
R18: Research Demonstration and
Dissemination Projects
R21: Exploratory/Developmental
Grants
R24: Resource-Related Research
Projects
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PViz: Most Common RCDC categories
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IN-SPIRE
FY2011 Physical Activity Portfolio Landscape
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Projects by Theme
From PA guidelines:
Population groups: women, children/youth
Obesity/weight
Diabetes
Cardiovascular disease
Environments: neighborhood, school, community
Accelerometry and pedometry
Exercise types: aerobic activity, resistance training,
bone-strengthening
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Projects by theme: FY08-FY11
IN-SPIRE
3500
0
500
1000
1500
2000
2500
3000
# o
f Pro
ject
s
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Projects by Theme: “Accelerometry” or
“Pedometry”
IN-SPIRE
140
0
20
40
60
80
100
120
FY08 FY09 FY10 FY11
# o
f Pro
ject
s
NIEHS
NIDA
NINDS
NIAAA
NIDCR
NIMHD
NIA
NINR
NIMH
NCRR
NIAMS
NIDDK
NICHD
NHLBI
NCI
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Common Themes: “Disparities”
PViz
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12%
0%
2%
4%
6%
8%
10%
FY08 FY09 FY10 FY11
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Trends in Exercise Categories %
of
tota
l pro
ject
s
Bone/Fracture/skeletal
Aerobic
Resistance training
IN-SPIRE
Top ICs
Bone: NIDDK, NIA, NIAMS
Aerobic: NHLBI, NIA, NCI,
NIDDK
Resistance: NCI, NIA, NIDDK
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Acknowledgements
Office of Portfolio Analysis
George Santangelo, Director
Carole Christian
Paula Fearon
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Summary Discussion
Were you surprised by any of the data – e.g. number of projects, themes of IC distribution?
If you were to make a recommendation on mechanism of award (R, K, P) and the state-of-the-science in PA research, what should NIH focus on for the next five years?
From information and themes depicted in the visualization, are there themes or areas of research that should receive increased emphasis, decreased emphasis?
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Additional discussion questions
Are there new approaches for strengthening the evidence base for future physical activity program and policy initiatives?
What are the key questions related to future studydesigns, physical activity measurement methodology, etc.?
What are the priority research and program needs?
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Supplemental Information
The following slides contain additional materials
produced from the portfolio analysis process
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Projects by IC: FY2011
NHLBI, 18%
NIDDK, 18%
NCI, 18%
NICHD, 10%
NIA, 8%
NIMHD, 5%
Other (NINDS, NCCAM,
NIEHS, NIDCD, NIAAA, NIGMS,
NIDCR, NLM, NEI, NHGRI,
FIC), 5%
NINR, 4%
NIAMS, 4%
NIMH, 3% NIDA, 2% NCRR, 2%
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Distribution of Projects by Activity
Distribution of projects by activity (FY08-FY11)
F 2%
Other 6%
U 9%
K 9%
P 10%
R (not R01) 23%
R01 41%
Distribution of projects by activity (FY11)
F 2%
Other 4%
U 7%
K 12%
P 11%
R (not R01) 20%
R01 44%
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Distribution by Funding Mechanism
P- Research Program Projects and Centers
P20 30%
P30 22%
P01 19%
P60 18%
P50 9%
P41 2%
P grants
P01: Research Program Projects
P20: Exploratory Grants
P30: Center Core Grants
P41: Biotechnology Resource
Grants
P50: Specialized Center
P60: Comprehensive Center
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Distribution by Funding Mechanism
K- Research Career Programs
K23 36%
K01 27%
K07 17%
K24 7%
K (others) 13%
K grants
K01: Research Scientist
Development Award
K07: Academic/Teacher Award
K23: Mentored Patient-Oriented
Research Career Development
Award
K24: Midcareer Investigator Award
in Patient-Oriented Research
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Distribution by Funding Mechanism
U- Cooperative Agreements
U01 69%
U54 18%
U10 5%
U13 4%
U19 3%
U (others) 1%
U grants
U01: Research Project
U10: Cooperative Clinical
Research U13: Conference
U19: Research Program
U54: Specialized Center
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Common Themes: “Obesity”
PViz
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Common Themes “Women”
PViz