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    The Pharmacists Role

    and ResponseSeptember 28, 2005

    Sheeba Samuel, Pharm.D.Clinical Assistant Professor

    Ernest Mario School of PharmacyRutgers, The State University of New Jersey

    Clinical PharmacistHackensack University Medical Center

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    Terminology used in Preparation

    and Response

    Mitigation Measures employed before an incident occurs to reduce

    damage

    Preparedness Activities that are conducted to improve readiness before a

    disaster

    Response

    Actions that deal with the consequences during a disaster Recovery

    Procedures that help normalize business operations

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    Federal Disaster Response

    Organizations

    Federal Emergency Management Agency (FEMA)

    National Response Plan (NRP)

    National Disaster Medical System (NDMS)

    Disaster Medical Assistance Teams (DMATs)

    Metropolitan Medical Response System (MMRS)

    National Pharmacy Response Team (NPRT)

    Centers for Disease Control and Prevention (CDC)

    Strategic National Stockpile (SNS)

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    Federal Emergency Management

    Agency (FEMA)

    Coordinates responsibility for all disasters

    Provides funding at the request of the governor

    Assists state and local organizations to mitigate,prepare for, respond and recover fromemergencies

    Developed the federal response plan

    Organizes federal assistance into 12 categories Examples: search and rescue, transportation, food, health

    and medical services, communication, etc.

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    National Response Plan (NRP)

    Developed as per Homeland Security PresidentialDirective

    Purpose

    Align federal coordination structures, capabilities, andresources

    Goal

    Improve coordination among federal, state, local and tribalorganizations

    Template: National Disaster Medical System (NDMS)

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    National Disaster Medical System

    (NDMS)

    Cooperative effort between 4 agencies Department of Health and Human Services Department of Defense Department of Veterans Affairs FEMA

    Partnership between federal and private sectors Volunteer based 3 major responsibilities

    Provide hospital beds Establish Disaster Medical Assistance Teams (DMATs) Establish specialty DMATs

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    Disaster Medical Assistance Teams

    (DMATs)

    98 state-based teams

    35 medical and support personnel: physicians, nurses,pharmacists, paramedics

    Process 200-250 patients in 24 hour period 26 considered to be readiness level 1 (R1)

    Must meet three requirements

    Be adequately trained and equipped Be able to care for themselves

    Be fully prepared going into disaster to not add toburden of overwhelming infrastructure

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    Disaster Medical Assistance Teams

    (DMATs)

    Provide four services

    Search and rescue

    Triage and initial stabilization Provide definitive medical

    care

    Evacuation

    Gaudette R, Schynitzer , George E, Briggs SM. Lessons Learned from the September 11 th World Trade

    Center Disaster: Pharmacy Preparedness and Participation in an International Medical and Surgical

    Response Team. Pharmacotherapy 2002;22(3):271-81.

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    Specialty DMATs

    Trauma

    Burns

    PediatricsVeterinary Medical Assistance Teams (VMATs)

    Disaster Mortuary Operation Response Teams

    (DMORTs) National Medical Response Teams (NMRTs)

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    Metropolitan Medical Response

    System (MMRS)

    Public and Private sector agencies broughttogether to enhance emergency preparednessand response

    Representatives from local police and firedepartments, hospitals, professional organizations,community and state agencies, and federal groups

    Required to have well-coordinated plan torespond to emergencies

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    National Pharmacy Response Team

    (NPRT)

    Includes pharmacists, pharmacy technicians, pharmacystudents

    Goal: assist in chemoprophylaxis or mass vaccination

    Become temporary federal employee

    Paid salary

    Reimbursed for travel and per diem expenses

    Liability coverage outside of state of licensure

    Deployed for no longer than 2 weeks Required to complete web-based training program, be

    current with treatment recommendations

    Application available at: http://ndms.fema.gov/forms.html

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    Centers for Disease Control and

    Prevention

    Prepare and respond to public health emergencies

    Conduct investigations into health effects and medical

    consequences Assess health and medical needs of disaster victims

    Develop and maintain national systems for acuteenvironmental hazard surveillance

    Provide epidemiologic, laboratory and other scientificservices to agencies involved in disaster planning andresponse

    http://www.in.gov/isdh/bioterrorism/manual/image43.gif

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    Strategic National Stockpile (SNS)

    Previously known as National Pharmaceutical Stockpile(NPS) established in 1999

    Managed by CDC National repository of antibiotics, chemical antidotes,

    antitoxins, life-support medications, medical/surgicalsupplies

    Goal: Ensure rapid delivery within 12 hours 3 main components

    12 hour push packages Enough drugs per packet to treat >100,000 people

    Vendor-managed inventory CDC maintains supply of chemical antidotes

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    SNS

    Can be requested by the state and shipment begin within 12hours pending federal government approval

    State responsible to provide manpower to dissemble packagingand transport pharmaceuticals

    Must factor in time to distribute Role of pharmacy personnel

    Ensure proper storage Provide recommendations for therapeutic alternatives Patient screening and triage

    Dispensing of pharmaceuticals Immunizations Patient counseling and compliance

    May extend expiration date

    http://www.hhs.state.ne.us/images/BT/nps.jpg

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    ASHP Statement on the Role of Health-

    System Pharmacists in Emergency

    Preparedness Pharmacists should play a key role in planning and execution of

    Pharmaceutical distribution and control Drug therapy management of patients

    Be involved in the following Development of guidelines Selection of pharmaceuticals and supplies for national, regional and local

    emergency inventories Ensure proper packaging, storage, handling, labeling and dispensing of

    emergency supplies Ensure proper deployment of emergency supply of pharmaceuticals Ensure appropriate education and counseling

    Advise public health officials on appropriate messages to conveyto the public

    Collaborate with physicians in managing drug therapy

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    Commitments made by ASHP

    Maintain electronic communications network

    Disseminate prompt information to ASHPmembers

    Disseminate timely evidence-based informationabout pharmaceuticals

    Meet with government officials and others

    regarding involvement of health-systempharmacists in emergency preparedness andcounterterrorism

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    Key Roles of a Pharmacist in

    Bioterrorism

    Surveillance

    Information

    Patient education and counseling

    Distribution of pharmaceuticals and medicalsupplies

    Administration of vaccines

    Evaluation/Triage

    Community planning and preparation

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    Surveillance

    Observe patients and their health needs

    Monitor and report any identified increases inpurchases of over-the-counter products forfever, pain or diarrhea

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    Information

    Remain calm and provide reassurance

    Be assertive

    Educate public, media and health professionals Prevent irrational behavior

    Obtain medication history and allergies

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    Patient Education and Counseling

    Ensure appropriate use and safety

    Prevent toxicities and side effects

    Enable identification of other medical andpsychological conditions

    Monitor for safety, efficacy and adherence

    Monitor for side effects

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    Distribution of Pharmaceutical and

    Medical Supplies

    Obtain extra pharmaceuticals from wholesalers

    Keep medications organized and under closesupervision

    Maintain security of controlled substances

    Package and label appropriately

    Prepare drugs onsite Monitor usage of drugs and predict which drugs

    need to be ordered

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    Administration of Vaccines

    Role of pharmacist is moving from distributorof vaccines to administrator of vaccines

    Pharmacists must be trained and educated in the

    technique of providing immunizations Growing number of pharmacists who are

    certified to immunize

    Target vaccines associated with bioterrorism: Smallpox

    Anthrax

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    Evaluation and Triage

    Triaging disaster victims

    Trauma management

    Prevent communicable diseasesAssist in transporting patients to shelters or

    homes

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    Community Planning and

    Preparation

    Contact local and state public health and emergencymedical officials to become part of emergency responseteam

    Coordinate actions with state board of pharmacy Contact prescription drug benefit plans regarding

    protocols for emergency re-fills Set up a handbook of contact information

    Wholesalers, distributors, manufacturers, communicationscompanies

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    Pharmacy Emergency Response

    Team (PERT)

    Trained to respond to chemical, biological, radiological, andnuclear agents

    Identify a lead pharmacist and set responsibilities for teammembers

    Involvement of pharmacy director, administrative support,clinical pharmacists

    Establish collaboration and coordination of the role pharmacyhas in disaster management

    Set procedures for emergency cart fills Resources are provided for efficient communication and

    protection

    Provide staff education

    Conduct drills to optimize functioning of the team

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    How to Prepare: Be Educated and

    Trained

    Become familiar with agents of concern, theirtreatment, prophylaxis and epidemiology

    Take training classes in emergency preparedness

    Learn first aid and become certified incardiopulmonary resuscitation (CPR) andadvanced cardiac life support (ACLS)

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    How to Prepare: Get Involved

    Develop the following Antibiotic selection guidelines

    Dosing charts for pediatric patients

    Counseling information

    Immunization guidelines (especially for high risk patients) Post exposure prophylaxis recommendations both primary and secondary

    exposure

    Assist in writing pharmaceutical distribution plans

    Take part in development of guidelines or treatment algorithms

    in management of patients exposed to bioterrorism Work with wholesalers to develop plans to obtain emergency

    pharmaceuticals

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    How to Prepare: Get Involved

    Teach other pharmacists, nurses, and medicalprofessionals

    Become certified to administer vaccines

    Develop programs for mass prophylaxisfocusing on issues of drug security, triage ofpatients, and counseling

    Take part in practice drills or training exercises Federal government can send training, education and

    demonstration (TED) packages

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    Resources American Society of Health-System Pharmacists

    http://www.ashp.org/emergency/

    American Pharmaceutical Association (APhA) PharmacistResponse Center http://www.aphanet.org/pharmcare/responsecenter.htm

    American Medical Association http://www.ama-assn.org/ama/pub/category/6206.html

    Centers for Disease Control (Bioterrorism preparedness andresponse) www.bt.cdc.gov

    John Hopkins University for Civilian Biodefense Strategies http://www.upmc-biosecurity.org/

    Federal Emergency Management Agency http://www.fema.gov

    U.S. Food and Drug Administration http://www.fda.gov/oc/opacom/hottopics/bioterrorism.html

    National Disaster Medical System http://www.oep-ndms.dhhs.gov/

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    Conclusion

    Pharmacists are identified as being an activeparticipant in the preparation and response toevents related to bioterrorism

    Pharmacists need to be educated and be activelyinvolved

    Utilize the available resources

    Be available to volunteer assistance

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    References

    Terriff CM, Schwartz MD, Lomaestro BM. Bioterrorism: Pivotal Clinical Issues. Pharmacotherapy 2003;23(3):275-90.

    American Society of Health-System Pharmacists. ASHP Statement on the Role of Health-System Pharmacists inCounterterrorism. Am J Health-Syst Pharm 2002;59(3):282-3.

    American Society of Health-System Pharmacists. Summary of the Executive Session on Emergency Preparednessand the Pharmaceutical Supply Chain Am J Health-Syst Pharm 2002;59(3):247-53.

    Teeter DS. Bioterrorism Preparedness: Answers for the Health-System Pharmacist Am J Health-Syst Pharm2002;59(10):928-30.

    Gaudette R, Schynitzer , George E, Briggs SM. Lessons Learned from the September 11th World Trade CenterDisaster: Pharmacy Preparedness and Participation in an International Medical and Surgical Response Team.Pharmacotherapy 2002;22(3):271-81.

    Schultz CH, Koenig KL, Noji EK. Disaster Preparedness. In: Marx JA, Hockberger RS, Walls RN, editors. RosensEmergency Medicine Concepts and Clinical Practice. London: Mosby; 2002. p. 2631-45.

    Department of Homeland Security. National Response Plan; December 2004. Available from:http://www.dhs.gov/dhspublic/theme_home2.jsp

    Emergency Preparedness and Response. Centers for Disease Control and Prevention. Available from:http://www.bt.cdc.gov

    Cohen V. Organization of a health-system pharmacy team to respond to episodes of terrorism. Am J Health-SystPharm 2003;60:1257-63.

    APhA Pharmacist Response Center. Available from: http://www.aphanet.org/pharmcare/responsecenter.htm

    http://www.dhs.gov/dhspublic/theme_home2.jsphttp://www.bt.cdc.gov/http://www.bt.cdc.gov/http://www.dhs.gov/dhspublic/theme_home2.jsp