List of drugs for the exam on Pharmacology

Agents Affecting the Afferent NSNovocainum (Procaine) – [Local

anesthetic] - for infiltration anesthesia 0.25 and 0.5%, conducting – 1 and 2%, cerebrospinal – 5% solution. PA: Amp 0.25%, 0.5%, 1% –1,2,5,10 ml. Ung.5%

Lidocain – [Local anesthetic and Antiarrhythmic agent] PA: Amp 2%-10 ml, 10%-2 ml

Ultracain (Articaine) – [Local anesthetic] for infiltration and conducting anesthesia1%-0.5-3 ml. PA Amp 1% and 2%-1 ml

Anesthesine - [Local anesthetic] – PA: Tab 0.3, Supp 0.05-0.1

Tannine – [Astringent] PA: powder, 1-2% for rinsing of mouth, nose, throat, larynx, 3-10% for local lubrication of burns, scissures, ulcers, decubitus)

Carbo activatus [Adsorbent] – PA: Tab 0.5Menthol – [Irritant] PA: Sol. Spirit 1-2%

externally and POAmmoniac solution (Sol. Ammonii caustici

10%) - [Irritant] PA: vial 10 ml - a small piece of cotton or gauze wetted with the drug is brought to the nose inlet for inhalation in syncope conditions. It also has disinfectant properties and is used for surgeon’s hands cleansing.

Agents Affecting the Efferent NSAtropini sulfas – [M-Сholinoblocker] -

PA: amp 0.1%-1 ml IM or IV, Eye ointment 1%- 5-10 ml

Ipratropium bromide (Atrovent) – [M-cholinoblocker] PA: Aeroz 15 ml – 2 inhalations bid or tid

Platiphyllini hydrotartras - [M-Сholinoblocker] PA: Tab 0.005; Amp. 0.2 % - 1 ml IV, IM

Pirenzepine (Gastrozepin) – [M1-Сholinoblocker]: tb 50 mg, amp 0.5%-2 ml

Pilocarpini hydrochloridum – [M-Сholinomimetic] PA: Eye drops 1% and 2%, Ung 1% and 2% - 5-10 ml, Tab 5 mg. Adults: 5 mg PO tid.

Proserine (Neostigmine)- [Anticholinesterase]: tb. 0.015; Amp. 0.05% - 1 ml SC, IM

Galantamine hydrobromide - [Anticholinesterase] PA: Amp 0.1%, 0.5%, 1% - 1 ml SC

Alloximum – [AhE Reactivator] PA: Amp 0.075 (sol for inject 1 ml) IM

Izonitrozinum – [AhE Reactivator]: Amp 40%-3 ml IM

Tubocurarine chloride (Curarin)- [Non-Depolarizing Myorelaxant] PA: Amp. 1% - 1.5 ml IV

Ditiline - [Depolarizing Myorelaxant] PA: Amp. 2% - 5 and 10 ml IV

Adrenalini hydrochloridum - [α1 α2 β1 β2 - Adrenomimetic] PA: Amp. 0.1% - 1 ml SC, IM, IV; 1-2% - 5-10 ml Eye drops

Noradrenalini hydrotartras - [α1 α2 β1 - Adrenomimetic] PA: Amp. 0.2 % - 1 ml: 4-8 mg in 500 ml 5% Glucose or 0.9% NaCl IV infusion

Mesatone – [α1, α2 - Adrenomimetic] PA: Amp 1% - 1 ml SC, IM, IV

Salbutamol - [β2 - Adrenomimetic] PA: Aeroz, Tab 2 mg

Prazosine - [α1 - Adrenoblocker] PA: Tab 1; 3 and 5 mg

Anaprilinum - [β1 β2 - Adrenoblocker]: Tb 0.01, 0.04, amp 0.25%-1 ml

Metoprolol - [β1 -Adrenoblocker] PA: Tab 0.05, 0.1, Amp. 1 % - 5 ml

Reserpine - [Sympatholytic] PA: Tab 0.1 mg and 0.25 mg

General Anesthetics. Hypnotics. Antiepileptics

Ketamine (Kalipsol, Ketalar) – [Agent for Non-Inhalation Narcosis] PA: Amp 5%-10 ml IM and IV

Zolpidem – [Hypnotic] PA: Tab 10 mgZopiclone – [Hypnotic] PA: Tab 7.5 mgCarbamazepine – [Antiepileptic] PA: Tab

0.2Natrii oxybutyras - [Agent for Non-

Inhalation Narcosis, Antihypoxant] PA: Amp. 20 % - 10 ml IM, IV, syrup 5%-400 ml. PO 1 tbsp 2-3 times a day.

Natrii valproas – [Antiepileptic] PA: Tab 0.3

Levodopa - [AntiParkinson Agent] PA: Tab 0.25 and 0.5

Nitrasepam – [Tranquilizer] PA: Tab 5 mgPhenobarbitalum - [Antiepileptic] PA:

Tab 0.05, 0.1

Opioid and Non-Opioid AnalgesicsMorphini hydrochloridum - [Opioid

Analgesic]: Tb 0.01; Amp. 1 % - 1 ml SCPromedolum (Trimeperidine) - [Opioid

Analgesic] PA: Amp 1% and 2% - 1 ml SC, IM, IV

Acid acetylsalicylic -[NSAID] PA: Tab 0.25, 0.35, 0.5 g

Diclofenac-natrium - [NSAID] PA: Tab 0.025; Amp. 2.5% - 3 ml IM

Tramadole – [NSAID] PA: Caps 0.05, Amp 5%-1 and 2 ml IM, IV, SC

Naloxone – [NSAID] PA: Amp 0.04%-1 ml IM, IV

Analgine – [NSAID] PA: Tab 0.5, amp 25%-2 ml IM, IV

Paracetamol (Acetaminophen) – [Non-Narcotic Analgesic, Antipyretic] PA: Tab 0.2 g

Meloxicam – [NSAID, selective COX-2 inhibitor] PA: Tab 0.015

Celecoxib – [NSAID, selective COX-2 inhibitor] PA: Caps 0.1

Nimesulide – [NSAID, preferable COX-2 inhibitor] PA: tb 0.1

Antipsychotic Agents and LithiumAminazine - [Neuroleptic] PA: Amp. 2.5%

- 1 ml IM, IV; Dr. 0.025 gDroperidolum - [Neuroleptic] PA: Amp.

0.25% - 10 ml SC, IM, IVDiazepam – [Tranquilizer] PA: Tab 5 mg,

Amp 0.5%-2 ml IM, IVGidazepamum – [Tranquilizer] PA: Tab

0.02 and 0.05 gPhenazepamum - [Tranquilizer] PA: Tab

0.5 mg and 1 mgBuspirone – [Tranquilizer] PA: Tab 5 and

10 mgCoffeini - natrii benzoas - [CNS stimulant,

analeptic, respiratory stimulant] PA: Tab 0.1, 0.2; Amp 10% and 20% - 1 and 2ml IM, IV

Cordiamin – [Analeptic]: Amp 1 and 2 ml SC, IM, IV; Vial 15 ml PO 15-40 drops 2-3 times a day

Sulfocamphocaine - [Analeptic] PA: Amp 10%-2 ml SC, IM, IV

Tinctura Valerianae – [Sedative Agent] PA: Vial 30 ml PO

Etimizol – [Respiratory Stimulant] PA: Amp 1.5%-3 ml- 2 ml IM, IV

Amitriptylinum - [Antidepressant] PA: Tab 0.025, Amp.1% - 2 ml IM

Fluoxetine – [Antidepressant] PA: Tab 0.02

Sertraline (Zoloft) – [Antidepressant] PA: Caps 0.05 and 0.1

Piracetam (Nootropil)- [Nootrop]: Caps. 0.4, Amp. 20% - 5 ml IM, IV

Phenibutum – [Nootrop] PA: Tab 0.25Drugs Affecting the Respiratory Systems

Aminophilline (Euphilline) - [Spasmolytic, Broncholytic] PA: Tab 0.015; Amp. 24% - 1 ml IM, 2.4%-10 ml IV

Acetylcysteinum - [Mucolytic agent, antidote for Paracetamol overdose] PA: Amp. 10% and 20% - 10 ml; Tab 0.1 and 0.2. Adults and children: 1-2 ml of 10% or 10% solution by direct instillation into trachea as often as every hour; or 3-5 ml of 20% or 6-10 ml of 10% solution administered by nebulizer every 2-3 hours. Paracetamol toxicity: 10 g PO followed by 5 g q 4 hours for 17 doses (a total of 1,330 mg/kg).

Ambroxol (Lasolvan) - [Mucolytic agent] PA: Tab 0.03 PO

Bromhexine – [Mucolytic agent] PA: Tab 0.004 and 0.008 PO

Tusuprex – [Antitussive agent] PA: Tab 0.01 and 0.02 PO

Libexine – [Antitussive agent] PA: Tab 0.1 PO

CardiostimulantsDigoxin - [Cardiac Glycoside] PA: Tab

0.25 mg and 0.1 mg; Amp. 0.025% – 1 ml IVDobutamine - [β1-adrenomimetic] PA:

Amp. 5% - 5 ml IV infusionCorglycone - [Cardiac glycoside] PA: Amp

0.06%-1 ml IM, IVSthrophanthine – [Cardiac glycoside] PA:

Amp 0.025%-1 ml IVUnitiolum [Antidotes – donor of

Sulfhydric groups] PA: Amp 5%-5 ml IM, IV infusion

Antianginal and antiarrhythmic agentsNitroglycerinum – [Nitrate, Antianginal

agent] PA: Tab 0.5 mg (Sublingual), Vial 1% spirit – 5 ml, Aerosol (lingual) 0.4 mg/metered spray; 2% ointment (Topical)

Isosorbide mononitrate – [Nitrate, Antianginal agent] PA: Tab 10 and 20 mg PO

Amlodipine – [Dihydropyridine Ca2+

channel blocker] PA: Tab 2.5, 5 and 10 mg POVerapamil – [Phenylalkylamine Ca2+

channel blocker] PA: Tab 0.04, 0.08, Amp 0.25%-2 ml IV

Novocainamide – [Antiarrhythmic agent]: Tab 0.25, Amp 10%-5 ml IV

Amiodaronum - [Antiarrhythmic agent] PA: Tab 0.2, Amp. 5% - 3 ml IV infusion

Molsidomine – [Peripheral vasodilator] PA: Tab 0.002 PO

A. Antihypertensive agents. Lipid-lowering agents. Angioprotectors

Captoprilum (Capoten) - [IACE] PA: Tab 25 and 50 mg PO

Lisinipril – [IACE] PA: Tab 10, 20 and 40 mg PO

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Enalapril (Renitec) - [IACE] PA: Tab 5, 10 and 20 mg PO

Drotaverine (No-spa) – [Spasmolytic]: Tab 0.04, Amp 2%-2 ml IM, IV

Fenofibrat – [Lipid-lowering agent] PA: Caps 0.1 PO

Lipostabil – [Lipid-lowering agent] PA: Caps PO, Amp 10 ml IV

Probucol – [Lipid-lowering agent] PA: Tab 0.25 and 0.5 PO

Lovastatine – [Lipid-lowering agent, HMG-CoA Reductase Inhibitor] PA: Tab 10, 20 and 40 mg PO

Magnesii sulfas - [Laxative, spasmolytic, sedative, cholagogue] PA: Amp 20% and 25% - 10 ml, powder

Nifedipine – [Dihydropyridine Ca2+ channel blocker] PA: Tab 0.01

Pentoxyphilline – [Peripheral vasodilator] PA: Tab 0.1 g, Amp 2%-5 ml

Clopheline – [α2- Adrenomimetic] PA: Tab 0.075 mg and 0.15 mg, Amp 0.01% - 1 ml

Drugs Used in Gastrointestinal Diseases

Metoclopramid (Cerucal) – [Antiemetic] PA: Tab 10 mg, amp 0.5%-2 ml IM, IV

Ranitidine – [H2 antagonist] PA: Tab 0.15 g

Famotidine – [H2 antagonist] PA: Tab 0.02 and 0.04

Almagel – [Astringent] PA: Vial 170 mlContrical (Aprotinin, Trasylol) –

[Antienenzyme, Antifibrinolytic] PA: Vial 30,000 and 50,000 UA IV infusion

Cholosasum (syrup from Wild rose’ fruits) – [Cholagogue]: vial 300 ml

Bisacodyl – [Purgative] PA: tb 5 mg, supp 10 mg

Omeprazole – [Proton Pump Inhibitor] PA: caps 20 mg

Pancreatin – [Digestant] PA: tb 0.25‘Allocholum’ – [Cholagogue] PA: tb

officinal (bile, Carbo activatus, Extr. from Garlic and Nettle)

Siliborum – [Hepatoprotector] PA: tb 0.04Essentiale – [Hepatoprotector] PA: caps

officinal, amp 5 mlAgents affecting the Kidney and Uterus

Hydrochlorthiazide [Thiazide

Diuretic] PA: Tab 25 and 100 mg

Furosemide [Loop Diuretic] PA: tb 0.04, amp 1%-2 ml

Spironolactone [Potassium Sparing Diuretic – Aldosterone antagonist] PA: Tab 25 mg

Oxytocinum – [Posterior Pituitary Hormone - Uterine stimulant] PA: amp 1 ml (5 UA)

Ergometrine maleate – [an Ergot alkaloid - Uterine stimulant] PA: tb 0.2 mg, amp 0.02%-1 ml IM, IV

Dinoprost – [Uterine stimulant] PA: Amp 0.5%-1 ml Intraamnionly and Extraamnionly

Fenoterol (Partusisten) [Tocolytic] PA: Aeroz 15 ml, Tab 5 mg, Amp 0.005% - 10 ml

Drugs affecting the Blood

Filgrastim -[Leucopoiesis

Stimulant] PA: (Vial 0.3 mg/ml and

0.48 mg/ml IV infusion with 5%

Glucose)

Methyluracilum – [Leucopoiesis Stimulant] PA: Tab 0.5 PO, Supp 0.5 per rectum

Fercovenum – [Erythropoiesis Stimulant] PA: amp 5 ml (1 ml: 20 mg Fe and 90 μg Co) IV

Cyanocobalamine - [Erythropoiesis Stimulant] PA: amp 0.01%, 0.05% and 0.1%-1 ml IM, IV

Acidum Folicum – [Erythropoiesis Stimulant] PA: tb 1 mg PO

Heparinum – [Anticoagulant of direct action] PA: vial 5 ml (5,000 UA/ml) SC, IM, IV

Fraxiparin – [Anticoagulant of direct action] PA: Syringe/injections 1 ml (1 ml – 9,500 IU) SC

Neodicumarinum – [Anticoagulant of indirect action] PA: Tab 0.05 and 0.1

Vicasolum – [Coagulant] PA: Tab 15 mg, Amp 1%-1 ml IM, IV

Acidum Aminocapronicum – [Antifibrinolytic] PA: Vial 5%-100 ml IV infusion

Epogen (Eprex, Epoetinum α) – [Erythropoiesis Stimulant] PA: vial 2,000 UA/ml; 4,000 UA/ml; 10,000 UA/ml SC or IV

VitaminsThiamini chloridum – [Vitamin B1] PA:

Tab 5mg and 10 mg, Amp 5%-1 ml IM, IVAcidum Nicotinicum – [Vitamin PP] PA:

Tab 0.1 g and 0.5 g, Amp 10%-1 ml IM, IV

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Ergocalciferolum – [Vitamin D2] PA: Dr 500 IU, Sol. Oleosae 0.5%-10 ml (1 drop–5,000 IU) PO

Retinoli acetas – [Vitamin A] PA: Dr 3,300 IU, Sol. Oleosae 3.44% and 8.6% - 10 ml PO

Acidum Ascorbinicum – [Vitamin C] tb 0.05 and 0.1, amp 5% and 10% - 1 and 2 ml IM, IV

Rutinum – [Vitamin P] PA: Tab 0.02 g POTocopheroli acetas – [Vitamin E] PA:

Vial – Sol. Oleosae 5%, 10% and 30% - 50 ml. PO 0.05-0.1 g a day, Amp - Sol. Oleosae 5%, 10% and 30% - 1 ml IM

HormonesCorticotropine (ACTH) [Anterior Pituitary

Hormone] PA: Vial 2 and 5 ml, 10-40 IU/ml. Primarily for the diagnosis of disorders of pituitary adrenal axis. 25 IU is infused IV and 24 hr urine is collected. If <74 μ mole of 17-hydrocorticosteroids are present in the 24 hr urine – adrenal insufficiency is indicated.

L-Thyroxine [Thyroid Hormone] PA: Tab 50 and 100 mg

Mercazolilum (Methimazole) [Antithyroid drug – Thyroid Inhibitor] PA: Tab 5 mg PO 3-4 times a day

Insuline [Pancreatic Hormone] PA: Vial 5 and 10 ml (40 and 80 UA/ml) SC, IV infusion: individualized dosage adjusted according to patient’s blood and urine glucose concentration

Glibenclamide [Sulfonylureas – Oral Hypoglycemic Drugs]: Tab 5 mg

Metformin [Biguanids – Oral Hypoglycemic Drugs] PA: Tab 0.5 and 0.85 g. PO 0.5 bid or 0.85 g PO once daily with morning meal

Prednisolone [Corticosteroid] PA: Tab 1 and 5 mg, Amp 3%-1 ml IM, IV

Progesteronum [Estrogen] PA: Amp Sol. Oleosae 1% and 2.5 % - 1 ml IM

Testosterone propionate [Androgen] PA: Amp ol 1% and 5% - 1 ml

Androcur (Cyproterone Acetate) [Antiandrogen] PA: Tab 50 mg, Amp 10%-3 ml

Retabolile (Nandrolone) [Anabolic steroid] PA: Amp Sol. Oleosae 5% -1 ml IM

Enzyme anti-enzyme agents.Salts, Acids, Alkalis. Plasma

substitutesLydazum (Hyaluronidase) [Protein

enzyme] PA: Vial 64 CU

Calcii chloridum [Macro and microelements] PA: Amp 10%-5 and 10 ml IV, PO Sol 10% 1 tbsp tid

Calcii gluconas [Macro and microelements] PA: tb 0.5, amp 10%-5 and 10 ml

Natrii hydrocarbonate [Macro and microelements] PA: tb 0.3 and 0.5, amp 4%-20 ml

Asparcam [Macro and microelements]: officinal tb, amp 5 and 10 ml

Glucose [Carbohydrate – Total Parenteral Nutrition component, caloric agent, fluid volume replacement] PA: Vial 5%, 10%, 20% - 200 and 400 ml

Magnesii sulfas [Macro and microelements] - amp 20 and 25%-10 ml

Sol. Natrii chloridum [Macro and microelements] PA: 0.9% isotonica pro injectionibus – 5, 10 and 20 ml, 10%-200 and 400 mlAntiallergic and Immunomodulating agents

Dimedrolum (Diphenhydramine) [1st Generation H1 antihistaminic] PA: Tab 0.02; 0.03; 0.05 g, Amp. 1% - 1ml IM, IV

Suprastine [1st Generation H1

antihistaminic] PA: tb 25 mg, amp 2%-1 mlLoratidine [2nd Generation H1

antihistaminic] PA: Tab 10 mgThymogen [Immunostimulant] PA: Vial

0.01% - 10 ml i/nasally or SC, IM 0.5-1 ml qdCycloferone [Immunostimulant] PA:

Amp 12.5%-2 ml IM or IV, Tab 0.15Laferone (Interferone α)

[Immunostimulant] PA: amp 1,000,000 IU and 3,000,000 IU SC, amp 100,000 IU (i/nasal)

A. AntisepticsHydrogenium peroxidum [Antiseptics -

Oxidant] PA:Vial 3%-30 mlKalii permanganas [Antiseptics - Oxidant]

PA: Powder, 0.1% - lavage of stomachViride nitens (Brilliant green) [Antiseptics

- Dyes] PA: Vial – Sol. spirit 1% and 2% - 10 ml

Iodine [Antiseptics - halogen] PA: Sol. spirit 5%-10 ml

Ioddicerinum [Antiseptics - halogen] PA: Vial 25 ml – 0.5%-for disinfection of wound, burns

Chlorhexidinum [Antiseptics - Biguanide] PA: Vial 20%-500 ml – only locally as 0.5% spirit or 1% water solution for surgical scrub, neonatal bath, mouthwash, obstetrics and a general skin antiseptic

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Furacilinum [Antiseptics – Furan derivative] PA: Tab 0.1; 0.02, Powder, 0.2% solution and cream

Spiritus aethylicus [Antiseptics -

Alcohols]: Vial 70%, 95% - 100 ml

Antibiotics and Antifungal DrugsBensilpenicillini-natrii [Penicillin

antibiotic] PA: Vial 500,000 UA IM, IV 3-4 hourly

Bicillinum-5 [Penicillin antibiotic] PA: Vial 1,500,000 UA IM every 4 weeks

Amoxycillin [Penicillin antibiotic] PA: Tab 1.0; Caps. 0.25, 0.5. PO 0.5-0.75 bid, in severe cases ad 1.0 g tid (typhoid, bronchitis, urinary infections, Subacute bacterial endocarditis and gonorrhea)

Ceftriaxon [3d generation Cephalosporins] PA: Vial 0.5 and 1.0

Doxycyclini hydrochloridum [Tetracycline antibiotic] PA: Tab 0.1 g

Gentamicini sulfas [Aminoglycoside antibiotic] PA: Amp 4% - 2 ml IM, IV 2-3 times a day

Amikacini sulfas [Aminoglycoside antibiotic] PA: Amp 5%, 12.5% and 25% - 2 ml IM, IV infusion 2-3 times a day

Azithromycin (Sumamed) [Macrolide antibiotic, subgroup of azalides] PA: Tab 0.5 g to be taken 1 hr before or 2 hr after meal. PO 0.5 g once daily (children above 6 month 10 mg/kg) for 3 days is sufficient for most infections. Urogenital infections (including gonorrhea) in both men and women - 1.0 g single dose is curative.

Nystatinum [Antifungal polyene antibiotic] PA: Tab 250,000 and 500,000 UA PO 3-4 times a day

Clotrimazole [Antifungal - Imidazoles] PA: Cream 1% - 20.0, Vial 1%-15 ml, Tab vaginal 0.1 g

Itraconazole [Antifungal - Triazoles] PA: Caps 0.1. PO 0.2 qd or bid for 3 months or more

Synthetic antimicrobic agentsCo-Trimoxazole [combination of

Sulfamethoxazole and Trimethoprime] PA: Tab 120 (80+40) and 480 (400+80) mg

Ciprofloxacin [Fluoroquinolones] PA: Tab 0.5 and 0.75 g PO bid for 10 days; Gonorrhoea – single 0.5 g dose is nearly 100% curative; Amp 1%-10 ml, vial 0.2%-50 and 100 ml IV infusion 12 hourly

Agents to teat Tuberculosis & Antiviral Drugs

Isoniazidum [1st line Antitubercular drug] PA: Tab 0.3 g PO 2-3 times a day, Amp 10%-5 ml IM or IV slowly qd № 30-150

Pirazinamide [1st line Antitubercular drug] PA: Tab 0.25 and 0.5 g PO 1.0 g bid

Rifampicinum [1st line Antitubercular antibiotic] PA: Caps 0.15, 0.3 and 0.45 g PO qd

Azidotimidine (Retrovir, Zidovudine) [Antiviral drug] PA: Caps 0.1 and 0.25 g PO 5-6 times a day; Vial 2%-20 ml IV infusion

Aciclovir [Antiviral drug] PA: Vial 0.25 IV or IV infusion tid, Tab 0.4 and 0.8 4-5 times a day, eye ointment 5%-30 ml

Remantadine [Antiviral drug] PA: Tab

0.05. PO 1.0 bid

Antiprotozoal DrugsChingaminum (Chloroquin, Delagil)

[Antimalarial Drug] PA: Tab 0.25. PO 1st day: 1.0 once (4 tb), then 0.5 3-4 times a day, 2nd

and 3rd days 0.5 qd. Amp 5% - 5 ml IM 10 ml every 6-8 hr (not >3 times) or IV in Sol. Glucose 40%-10-20 ml or Sol. Natrii chloridum 0.9% isotonica only in severe cases

Mebendazole (Vermox) [Anthelmintic] PA: Tab 0.1 bid for 3 days

Metronidazolum (Trichopol)

[Antiprotozoal drug]: Tab 0.25 and 0.5

Manifestation and emergence

treatment of acute poisonings with medical

agents

Adrenaline, Noradrenaline, Mesatone,

Aminazine, Paracetamole, Butadione,

Atropine, Morphine, POC (phosphoric-organic

compounds), Phenobarbitale, Diazepam,

Clopheline, Novocaine, Ethanol,

Pachycarpine, Anapriline, Closepine,

Indomethacine, Dimedrole

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