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Page 1: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

CONTROLPESTGUIDE

2012

A SUPPLEMENT TO

Page 2: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

2012 | PEST CONTROL GUIDE | 3

Pest Listings

Insect or Mite Pest

Pest Control Material Common Name

Pest Control Material Trade Name(s)

Restricted Entry Interval (REI) Mode of Action

APHIDS Abamectin Avid 12 hours GABA1 Chloride Channel ActivatorAcephate Orthene/Precise 24/12 hours Acetylcholine Esterase Inhibitor

Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Beauveria bassiana BotaniGard/Naturalis 4 hours

Bifenazate + Abamectin Sirocco 12 hours Mitochondria Electron Transport Inhibitor + GABA Chloride Channel Activator

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium Channels Chlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor

Clarified hydrophobic extract of neem oil Triact 4 hours Suffocation or Membrane Disruptor

Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium ChannelsDinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic

Flonicamid Aria 12 hours Selective Feeding Blocker/Blocks Action of Potassium Channels

Fluvalinate Mavrik 12 hours Prolong Opening of Sodium Channels

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Kinoprene Enstar II/AQ 4 hours Juvenile Hormone Mimic

Greenhouse pest management involves using a multitude of strategies in order to minimize

the prospect of dealing with arthropod pest (insect and mite) populations. The use of pest control materials (insec-ticides and miticides) is one compo-nent of a pest management program that also includes pest identification and monitoring along with cultural, physical, and biological control. Proper stewardship of pest control materials includes resistance management by rotating products with different modes

Pest control materials for managing insect and mite pests of greenhouse-grown crops

By Raymond A. Cloyd // Department of Entomology //Kansas State University

of action. A system has been devel-oped by the Insecticide Resistance Action Committee (IRAC) to facilitate the implementation of appropriate rotation programs. Pest control materi-als have been assigned a designated number (sometimes number and letter combinations) based on their mode of action. For more information consult the IRAC website (www.irac.online.org). The information presented in this chart is not a substitute for the label. It is important to read and understand all information presented on the label be-

fore using any pest control material. Be sure to check county and state regula-tions to determine if there are any local restrictions associated with the use of specific pest control materials listed in this chart.

Pest Control Guide

Use this guide to find controls labeled for aphids.

Page 3: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

4 | PEST CONTROL GUIDE | 2012

Pest Control Guide

Insect or Mite Pest

Pest Control Material Common Name

Pest Control Material Trade Name(s)

Restricted Entry Interval (REI) Mode of Action

Methiocarb Mesurol 24 hours Acetylcholine Esterase Inhibitor Paecilomyces fumosoroseus PFR-97/NoFly 4 hours

Petroleum oil Ultra-Pure Oil/SuffOil-X 4 hours Suffocation or Membrane DisruptorPotassium salts of fatty

acids M-Pede 12 hours Desiccation or Membrane Disruptor

Pymetrozine Endeavor 12 hours Selective Feeding Blocker

Pyrethrins Pyreth-It/Pyrethrum 12 hours Prolong Opening of Sodium Channels

Spirotetramat Kontos 24 hours Lipid Biosynthesis Inhibitor

Thiamethoxam Flagship 12 hours Nicotinic Acetylcholine Receptor Disruptor Tolfenpyrad Hachi-Hachi 12 hours Mitochondria Electron Transport Inhibitor

BROAD MITE Abamectin Avid 12 hours GABA Chloride Channel Activator

Bifenazate + Abamectin Sirocco 12 hours Mitochondria Electron Transport Inhibitor + GABA Chloride Channel Activator

Chlorfenapyr Pylon 12 hours Oxidative Phosphorylation Uncoupler Fenpyroximate Akari 12 hours Mitochondria Electron Transport Inhibitor

Pyridaben Sanmite 12 hours Mitochondria Electron Transport Inhibitor Spiromesifen Judo 12 hours Lipid Biosynthesis Inhibitor

CATERPILLARS Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Bacillus thuringiensis spp. kurstaki Dipel 4 hours Midgut Membrane Disruptor

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium ChannelsChlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium Channels

Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic Fenpropathrin Tame 24 hours Prolong Opening of Sodium Channels

Fluvalinate Mavrik 12 hours Prolong Opening of Sodium ChannelsPotassium salts of fatty

acids M-Pede 12 hours Desiccation or Membrane Disruptor

Novaluron Pedestal 12 hours Chitin Synthesis Inhibitor

Spinosad Conserve 4 hours Nicotinic Acetylcholine Receptor Agonist and GABA Chloride Channel Activator

Tolfenpyrad Hachi-Hachi 12 hours Mitochondria Electron Transport Inhibitor CYCLAMEN

MITE Abamectin Avid 12 hours GABA Chloride Channel Activator

Bifenazate + Abamectin Sirocco 12 hours Mitochondria Electron Transport Inhibitor + GABA Chloride Channel Activator

Chlorfenapyr Pylon 12 hours Oxidative Phosphorylation Uncoupler Fenpyroximate Akari 12 hours Mitochondria Electron Transport Inhibitor Spiromesifen Judo 12 hours Lipid Biosynthesis Inhibitor

FUNGUS GNAT LARVAE Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Bacillus thuringiensis spp. israelensis Gnatrol 4 hours Midgut Membrane Disruptor

Chlorfenapyr Pylon 12 hours Oxidative Phosphorylation UncouplerChlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor Cyromazine Citation 12 hours Chitin Synthesis Inhibitor

Diflubenzuron Adept 12 hours Chitin Synthesis Inhibitor

Dinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor

Page 4: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

2012 | PEST CONTROL GUIDE | 5

Pest Control Guide

Insect or Mite Pest

Pest Control Material Common Name

Pest Control Material Trade Name(s)

Restricted Entry Interval (REI) Mode of Action

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Kinoprene Enstar II/AQ 4 hours Juvenile Hormone Mimic Pyriproxyfen Distance 12 hours Juvenile Hormone Mimic

Steinernema feltiaeNemasys, NemaShield,

Scanmask, and Entonem

Thiamethoxam Flagship 12 hours Nicotinic Acetylcholine Receptor Disruptor FUNGUS GNAT

ADULTS Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium Channels

Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium ChannelsFenpropathrin Tame 24 hours Prolong Opening of Sodium Channels

Fluvalinate Mavrik 12 hours Prolong Opening of Sodium ChannelsPotassium salts of fatty

acids M-Pede 12 hours Desiccation or Membrane Disruptor

LEAFHOPPERS Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium ChannelsBuprofezin Talus 12 hours Chitin Synthesis Inhibitor Chlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium Channels

Dinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor Fluvalinate Mavrik 12 hours Prolong Opening of Sodium Channels

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Potassium salts of fatty acids M-Pede 12 hours Desiccation or Membrane Disruptor

Spirotetramat Kontos 24 hours Lipid Biosynthesis Inhibitor Tolfenpyrad Hachi-Hachi 12 hours Mitochondria Electron Transport Inhibitor

LEAFMINERS Abamectin Avid 12 hours GABA Chloride Channel Activator Acephate Orthene 24 hours Acetylcholine Esterase Inhibitor

Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Cyromazine Citation 12 hours Chitin Synthesis Inhibitor Dinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic Novaluron Pedestal 12 hours Chitin Synthesis Inhibitor

Spinosad Conserve 4 hours Nicotinic Acetylcholine Receptor Agonist and GABA Chloride Channel Activator

Thiamethoxam Flagship 12 hours Nicotinic Acetylcholine Receptor Disruptor MEALYBUGS Acephate Orthene/Precise 24/12 hours Acetylcholine Esterase Inhibitor

Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Beauveria bassiana BotaniGard/Naturalis 4 hours

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium ChannelsBuprofezin Talus 12 hours Chitin Synthesis Inhibitor Chlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor

Page 5: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

6 | PEST CONTROL GUIDE | 2012

Pest Control Guide

Insect or Mite Pest

Pest Control Material Common Name

Pest Control Material Trade Name(s)

Restricted Entry Interval (REI) Mode of Action

Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium ChannelsDinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic

Fenpropathrin Tame 24 hours Prolong Opening of Sodium Channels

Flonicamid Aria 12 hours Selective Feeding Blocker/Blocks Action of Potassium Channels

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Kinoprene Enstar II/AQ 4 hours Juvenile Hormone Mimic Petroleum oil Ultra-Pure Oil/SuffOil-X 4 hours Suffocation or Membrane Disruptor

Potassium salts of fatty acids M-Pede 12 hours Desiccation or Membrane Disruptor

Spirotetramat Kontos 24 hours Lipid Biosynthesis Inhibitor Thiamethoxam Flagship 12 hours Nicotinic Acetylcholine Receptor Disruptor

PLANT BUGS Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium ChannelsFluvalinate Mavrik 12 hours Prolong Opening of Sodium Channels

SCALES (HARD AND SOFT)a Acephate Orthene/Precise 24/12 hours Acetylcholine Esterase Inhibitor

Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium ChannelsBuprofezin Talus 12 hours Chitin Synthesis Inhibitor

Clarified hydrophobic extract of neem oil Triact 4 hours Suffocation or Membrane Disruptor

Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium ChannelsDinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Kinoprene Enstar II/AQ 4 hours Juvenile Hormone Mimic Petroleum oil Ultra-Pure Oil/SuffOil-X 4 hours Suffocation or Membrane Disruptor

Potassium salts of fatty acids M-Pede 12 hours Desiccation or Membrane Disruptor

Thiamethoxam Flagship 12 hours Nicotinic Acetylcholine Receptor Disruptor Tolfenpyrad Hachi-Hachi 12 hours Mitochondria Electron Transport Inhibitor

SHORE FLY Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Chlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor

Cyromazine Citation 12 hours Chitin Synthesis Inhibitor

Diflubenzuron Adept 12 hours Chitin Synthesis Inhibitor

Pyriproxyfen Distance 12 hours Juvenile Hormone Mimic

SLUG AND SNAIL Iron phosphate Sluggo 0 hours Inhibits Calcium Metabolism

Metaldehyde Deadline Refer to Label Central Nervous System Toxin

Methiocarb Mesurol 24 hours Acetylcholine Esterase Inhibitor

TWOSPOTTED SPIDER MITE Abamectin Avid 12 hours GABA Chloride Channel Activator

Acequinocyl Shuttle 12 hours Mitochondria Electron Transport Inhibitor

Bifenazate Floramite 4 hours Mitochondria Electron Transport Inhibitor

Page 6: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

2012 | PEST CONTROL GUIDE | 7

Pest Control Guide

Insect or Mite Pest

Pest Control Material Common Name

Pest Control Material Trade Name(s)

Restricted Entry Interval (REI) Mode of Action

Bifenazate + Abamectin Sirocco 12 hours Mitochondria Electron Transport Inhibitor + GABA Chloride Channel Activator

Chlorfenapyr Pylon 12 hours Oxidative Phosphorylation Uncoupler

Clarified hydrophobic extract of neem oil Triact 4 hours Suffocation or Membrane Disruptor

Clofentezine Ovation 12 hours Growth and Embryogenesis Inhibitor Etoxazole TetraSan 12 hours Chitin Synthesis Inhibitor

Fenazaquin Magus 12 hours Mitochondria Electron Transport Inhibitor

Fenbutatin-oxide (Hexakis) ProMite 48 hours Oxidative Phosphorylation Inhibitor

Fenpyroximate Akari 12 hours Mitochondria Electron Transport Inhibitor Hexythiazox Hexygon 12 hours Growth and Embryogenesis Inhibitor

Petroleum oil Ultra-Pure Oil/SuffOil-X 4 hours Suffocation or Membrane DisruptorPotassium salts of fatty

acids M-Pede 12 hours Desiccation or Membrane Disruptor

Pyridaben Sanmite 12 hours Mitochondria Electron Transport Inhibitor

Spiromesifen Judo 12 hours Lipid Biosynthesis Inhibitor

Spirotetramat Kontos 24 hours Lipid Biosynthesis Inhibitor

THRIPS Abamectin Avid 12 hours GABA Chloride Channel Activator

Acephate Orthene/Precise 24/12 hours Acetylcholine Esterase Inhibitor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Beauveria bassiana Botanigard/Naturalis 4 hours

Bifenazate + Abamectin Sirocco 12 hours Mitochondria Electron Transport Inhibitor + GABA Chloride Channel Activator

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium ChannelsChlorfenapyr Pylon 12 hours Oxidative Phosphorylation Uncoupler Chlorpyrifos DuraGuard 24 hours Acetylcholine Esterase Inhibitor

Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium Channels

Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic

Flonicamid Aria 12 hours Selective Feeding Blocker/Blocks Action of Potassium Channels

Fluvalinate Mavrik 12 hours Prolong Opening of Sodium ChannelsKinoprene Enstar II/AQ 4 hours Juvenile Hormone Mimic Methiocarb Mesurol 24 hours Acetylcholine Esterase Inhibitor Novaluron Pedestal 12 hours Chitin Synthesis Inhibitor

Paecilomyces fumosoroseus PFR-97/NoFly 4 hours

Pyrethrins Pyreth-It/Pyrethrum 12 hours Prolong Opening of Sodium ChannelsPyridalyl Overture 12 hours Mode of Action Unknown

Spinosad Conserve 4 hours Nicotinic Acetylcholine Receptor Agonist and GABA Chloride Channel Activator

Tolfenpyrad Hachi-Hachi 12 hours Mitochondria Electron Transport Inhibitor WHITEFLIES Abamectin Avid 12 hours GABA Chloride Channel Activator

Acephate Orthene/Precise 24/12 hours Acetylcholine Esterase Inhibitor Acetamiprid TriStar 12 hours Nicotinic Acetylcholine Receptor Disruptor

Azadirachtin Azatin/Ornazin/Molt-X/Azatrol 4/12/4/4 hours Ecdysone Antagonist

Beauveria bassiana Botanigard/Naturalis 4 hours

Bifenthrin Attain/Talstar 12 hours Prolong Opening of Sodium Channels

Page 7: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

8 | PEST CONTROL GUIDE | 2012

Pest Control Guide

Insect or Mite Pest

Pest Control Material Common Name

Pest Control Material Trade Name(s)

Restricted Entry Interval (REI) Mode of Action

Bifenazate + Abamectin Sirocco 12 hours Mitochondria Electron Transport Inhibitor + GABA Chloride Channel Activator

Buprofezin Talus 12 hours Chitin Synthesis Inhibitor Clarified hydrophobic

extract of neem oil Triact 4 hours Suffocation or Membrane Disruptor

Cyfluthrin Decathlon 12 hours Prolong Opening of Sodium Channels

Diflubenzuron Adept 12 hours Chitin Synthesis Inhibitor

Dinotefuran Safari 12 hours Nicotinic Acetylcholine Receptor Disruptor

Fenazaquin Magus 12 hours Mitochondria Electron Transport Inhibitor

Fenoxycarb Preclude 12 hours Juvenile Hormone Mimic

Fenpropathrin Tame 24 hours Prolong Opening of Sodium Channels

Flonicamid Aria 12 hours Selective Feeding Blocker/Blocks Action of Potassium Channels

Fluvalinate Mavrik 12 hours Prolong Opening of Sodium Channels

Imidacloprid Marathon/Benefit/Mantra 12 hours Nicotinic Acetylcholine Receptor Disruptor

Kinoprene Enstar II/AQ 4 hours Juvenile Hormone Mimic

Novaluron Pedestal 12 hours Chitin Synthesis Inhibitor

Paecilomyces fumosoroseus PFR-97/NoFly 4 hours

Petroleum oil Ultra-Pure Oil/SuffOil-X 4 hours Suffocation or Membrane Disruptor

Potassium salts of fatty acids M-Pede 12 hours Desiccation or Membrane Disruptor

Pymetrozine Endeavor 12 hours Selective Feeding Blocker

Pyrethrins Pyreth-It/Pyrethrum 12 hours Prolong Opening of Sodium Channels

Pyridaben Sanmite 12 hours Mitochondria Electron Transport Inhibitor

Pyriproxyfen Distance 12 hours Juvenile Hormone Mimic

Spiromesifen Judo 12 hours Lipid Biosynthesis Inhibitor

Spirotetramat Kontos 24 hours Lipid Biosynthesis Inhibitor

Thiamethoxam Flagship 12 hours Nicotinic Acetylcholine Receptor Disruptor

Tolfenpyrad Hachi-Hachi 12 hours Mitochondria Electron Transport Inhibitor

a Refer to label for specific scale species.1 GABA=Gamma-aminobutyric acid

For more: Raymond A. CloydKansas State University, Department of Entomology123 Waters Hall, Manhattan, Kansas 66506(785) 532-4750, [email protected]

Page 8: Pest Control Guidegiecdn.blob.core.windows.net/...supplementgm.pdf · A SUPPLEMENT TO. 2012 | PEST CONTROL GUIDE | 3 Pest Listings Insect or Mite Pest Pest Control Material Common

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2012 | PEST CONTROL GUIDE | 9

Pest Control Guide

greenhousemanagementonline.com/readerservice - #27

A useful tool for early detec-tion and pest management in greenhouses are the so-called

yellow sticky cards. Learn more about the data collected from the cards, what it means and how to understand it. Greenhouse owners and manag-ers should use this information when training workers to become scouts. Re-member, sticky traps will catch pests and beneficials. Always use sticky traps combined with other techniques. Do not rely on this method alone.

Learning pest I.D. Pictorial guides, experience and attending workshops and grower meetings are helpful. Get some kind of magnification equip-ment—a hand lens is a good start. With experience you will become acquainted with the major pest groups and will be able to easily identify them. If you are not sure, send samples to your nearest pest diagnostic clinic.

Sticky traps examination. If you want a picture of population trends, examine traps weekly. If you want to see a “snapshot” of pest activity at the moment, place traps in the green-house for a few hours once or twice each week. The important matter is to be consistent. Be careful about de-ploying traps just prior to using some pyrethroid insecticides. These insecti-cides can cause an increase in insect activity, leading to misleading conclu-sions about insecticide effectiveness and pest populations. Insect count can be facilitated by using sticky traps with a background grid. The grid becomes especially useful when there are many insects on the card.

Counting the pests. Depending on

Sticky traps: A useful tool for pest‑scouting programs

your objectives, you can count all of the pests on each trap, those on a one-inch vertical strip on each trap, or place pest numbers in categories, depending on estimated numbers. For example, categories could be none, few, some, too many. You will

have to establish these levels depend-ing on the pest crop and season. The numbers of western flower thrips that can be tolerated will be higher if INSV is not a problem. Do what you can ac-complish consistently.

— Ohio State University