Personalized Lifestyle Modification to Prevent

Cardiovascular Disease: A Case Study

BACKGROUND:

Routhenstein M* MS, RD, RDN, CDE, CDN, Black N BSpExSci, Lam Jie Lei T BSc (Hons), MSc , Joose J BNutrDiet (Hons), An LS BSc SpHSci, Axelrod V MS, Karpov P BS, LaRocco J MS, PhD,

Heng CK PhD, Ting P MBBS, MRCP (UK), MPH (Harvard), FACC, FAsCC, FAMS, Lal S MBBS, MS, PhD, Fathianathan M BS Mech Eng, PhD

RESULTS:

Cardiovascular disease (CVD) is the leading cause of deaths in the US, killing

801,000 Americans every year. About 85.6 million Americans are living with some

form of CVD, while over 49% of the population has at least one risk factor of

CVD. With only 32,000 cardiologists in the U.S., the demand for cardiologists far

exceeds supply, and the shortage is worsening with time.

Doctors currently have limited infrastructure and expertise to prescribe a lifestyle

modification based preventive cardiology solution to individuals at risk.

Personalized lifestyle intervention under clinical supervision when delivered

through an interactive tele-medicine platform, supported by a preventive

cardiology specialist team can lead to successful outcomes (significant reduction

in cardiovascular disease risk), as described in this case report. The results

demonstrate a potential approach to scaling preventive cardiology through doctors

and healthcare providers nationwide.

D

Fig 5. The preventive cardiology specialist provided John with recommendations on dietary

modifications (5a) based on nutrition parameters (5b), leading to an improved HLS (5c)

A BA’ B’

Lifestyle Analysis + CVD Risk Assessment (Baseline)

Fig 3. John’s Healthy Living Score (HLS) was

computed based on detailed data on his diet, sleep

patterns, stress levels, water intake and physical

activity recorded on the platform.

Fig 4. Tracking of individual lifestyle parameters including sleep (4a), smoking frequency (4b), diet -

scored using an eats well score methodology (4c) and Alternative Healthy Living Index-2010 (AHEI)

score (4d).

Fig 2. John’s baseline CVD risk profile.

The comprehensive risk assessment

scoring methodology incorporates blood

test results, physical examination reports

by the doctor, and a detailed analysis of

lifestyle (Healthy Living Score - HLS) over

a 1 week period.

Lifestyle Analysis + CVD Risk Assessment

after 11 weeks on the program

BASELINE

11 WEEKS

Clinical goals (prescribed by the doctor) for John were translated into

personalized lifestyle goals by the health coach, and were customized based

on both intensity and sequence of modifying different lifestyle parameters. Daily

interactions with the specialist over the platform further refined and enhanced

the personalization aspects of lifestyle intervention.

CARDIATRICS, 254 Canal Street, Suite 3005, New York 10013 *michelle@cardiatricshealth.com

Fig. 6. John’s compliance on the program was

carefully monitored and scored with respect to

adherence to all the lifestyle factors.

Fig.1 Lifestyle data was collected through a mobile

health & telemedicine platform and assessed by the

designated health coach (preventive cardiology

specialist).

Healthy Living Score (HLS)Sleep Chart

Clinically supervised lifestyle modification can lead to measurable reduction in CVD

risk, when enabled by a team of experts and a technology platform. The results

demonstrate a potential approach to scaling preventive cardiology through doctors and

healthcare providers nationwide.

Fig. 7. Risk profile and score demonstrated a significant reduction in John’s 10-year CVD risk after

11 weeks on the personalized lifestyle modification program.

John Doe (name changed), a 42 year old male subject was enrolled in a

personalized CVD risk assessment and lifestyle modification program as

prescribed by a physician in New York City.

Fig.4b

Fig.4a

Fig.4c

Fig.4d

CONCLUSION:

Fig.5c

Fig.5b

Fig.5a

METHODS:

ABSTRACT:

Personalized Lifestyle Modification

Fig. 7. Improvement in John’s Healthy Living

Score (HLS) at the 11th week of the program.