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1/9/2018 1 ©2018 MFMER | 3712003-1 Pericardial Diseases Illustrative Cases Jae K. Oh, MD ©2018 MFMER | 3712003-2 47 year old man Chest pain Not exertional Normal Examination Case #1

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Page 1: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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©2018 MFMER | 3712003-1

Pericardial DiseasesIllustrative Cases

Jae K. Oh, MD

©2018 MFMER | 3712003-2

47 year old man

•Chest pain

•Not exertional

•Normal Examination

Case #1

Page 2: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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©2018 MFMER | 3712003-3

47 year old man with chest pain

• Usually left side

• Heart shifted to left

• Mostly asymptomatic

• Strangulation can happen

©2018 MFMER | 3712003-4

Congenital Absence of the Pericardium

Snoopy Sign

Page 3: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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Pericardial CystCase #2

©2018 MFMER | 3712003-6

A large pericardial cyst

©2011 MFMER | slide-6

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Case #351 year old with SLE and BP 150/115

©2018 MFMER | 3712003-8

57 year old male with STEMIThrombolysis and Stent

Hypotensive and tachycardic

Case # 4Case #4

Page 5: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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©2018 MFMER | 3712003-9

57 year old man with STEMI

Hepatic vein diastolic reversal with expiration

RV Diastolic Collapse

©2018 MFMER | 3712003-10

Tamponade Physiology

Pressure

Volume over time

Rapid effusion Slow effusion

Criticaltamponade

Limit of pericardial stretch

NEJM 349: 684, 2003CP1299236-6

Page 6: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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©2018 MFMER | 3712003-11

Cardiac Tamponade

RV collapse Mitral inflow variation HV expiratory reversal

©2018 MFMER | 3712003-12

Hemo‐pericardiumCase #5

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©2018 MFMER | 3712003-13

Intramural Hematoma

©2018 MFMER | 3712003-14

66 year old woman with dyspneaPneumo-pericardium

PneGastro-pericardial fistulau

Case #6

Page 8: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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©2018 MFMER | 3712003-15

77 yo man with severe aortic stenosisTAVR and PM implantation & RV Perforation

Pericardiocentesis yielded 125 cc of bloody fluid

Case #7

©2018 MFMER | 3712003-16

77 yo man with severe aortic stenosisIncreasing dyspnea 2 months after pericardiocentesis

After Pericardiocentesis 2 months later

Page 9: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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Effusive-Constrictive Pericarditis

Interventricular Dependence

Expiratory diastolic flow reversal

©2018 MFMER | 3712003-18

Tamponade vs Effusive CP

Miranda et al. In Preparation

Page 10: Pericardial Diseases Illustrative Cases · After Pericardiocentesis 2 months later. 1/9/2018 9 ©2018 MFMER | 3712003-17 Effusive-Constrictive Pericarditis Interventricular Dependence

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©2011 MFMER | slide-19

MRI DE in 2 patients with Constriction

Circulation Oct 3rd 2011

Baseline

Medical RX

3 Months

©2018 MFMER | 3712003-20

©2011 MFMER | slide-20

One week of Steroid RxTransient Constrictive Pericarditis

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©2011 MFMER | slide-21

Transient ConstrictionReversible (N=14) Persistent (N=15)

Age 54 ± 17 59 ± 16

LVEF 57 ± 3 60 ± 3

E’ (cm/sec) 12 ± 1 11 ± 1

Steroid Rx 71 % 53 %

Pericardium 3.8 ± 0.6 mm 4.0 ± 0.6 mm

DE Pericardium 4.4 ± 0.4 mm 2.1 ± 0.4mm

Grade 3-4/4 DE 93 % 33 %

Sed rate 45 to 4 25 to 20

CRP 75 to 2 14 to 15

©2018 MFMER | 3712003-22

35 yo man presents with dyspnea and feverBP 80/40 mmHg

Case #8

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©2018 MFMER | 3712003-23

35 yo man with tamponade and feverTEE after pericardiocentesis

©2018 MFMER | 3712003-24

36 yo man with dyspnea, chest pain, and abd pain

Case #9

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©2018 MFMER | 3712003-25

36 yo man with dyspnea, chest pain, and abd pain

Case #9

©2018 MFMER | 3712003-26

36 yo man with dyspnea, chest pain, and abd pain

Case #9

Sarcoidosis

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©2018 MFMER | 3712003-27

Pericardial Diseases and TamponadeTake home message

• Always, identify underlying cause for pericarditis, pericardial effusion or tamponade

• Echo diagnosis of tamponade• Plethoric IVC• Diastolic collapse of RV, RA and LA• Interventricular dependence• Diastolic HV flow reversal with expiration

• We may be able to identify the patients who may develop effusive-constrictive pericarditis at the time of pericadiocentesis

©2018 MFMER | 3712003-28

Thank You !

[email protected]

[email protected]

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©2018 MFMER | 3712003-29

©2012 MFMER | 3213949-29

©2018 MFMER | 3712003-30

Questions & Discussion

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Welles-04-07.mov

Echo-Guided Pericardiocentesis

18%3%

Chest wall 79%

SubcostalLocation