perforator vein treatment - the venous · pdf fileperforator vein treatment: you can’t...
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Perforator Vein Treatment:
You can’t tell people what they want to hear…
If you also want to tell them the truth*
Steve Elias MD FACS FACPh
Director, Division of Vascular Surgery Vein Programs
Columbia University NY
Englewood NJ
Assistant Professor of Surgery
Columbia University NY
The Hold Steady. Soft In The Center.“Heaven is Whenever”.
2010; Key Hits Muy Interesante Music.
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Disclosure
Steve Elias, M.D.
I disclose the following financial relationship(s):
Consultant/Advisory Board: Covidien Inc, Vascular
Insights LLC
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Ceci n’est pas une pipe
“The Treachery of Images”: Rene Magritte
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Issues in General
Goal - heal ulcer & prevent recurrence
Decrease venous hypertension
GSV, VV, Perforators, Suprainguinal
Hypertensive threshold concept
How low is low enough
Anatomic ablation vs. clinical success
Ulcer Healing vs. Ulcer Recurrence
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DSM IV: Criteria
Personality Type - normal variant
Personality Disorder - pathologic
Incompetent person≠Pathologic person
Pathologic person=Incompetent person
Incompetent vs. Pathologic Perforator
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Primary criteriaReversal of flow > 0.5 seconds
Secondary criteriaBi-directional flow > 0.5 seconds
Perforator vein diameter > 3.0 mm
Size @ fascia > 3.0mm
= 90% incompetence
Size @ fascia > 4.0mm
= 100% incompetence
Sandri, JL. Diameter-reflux relationship in perforating veins of patients with varicose veins: JVS; 30,5,11999
Duplex Ultrasound:
Diagnostic Modality of Choice
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Incompetent or Pathologic?
“The duplex criteria for diagnosing IPVs are extremely important in the selection process…to ablate an IPV. An enlarged IPV diameter at the fascia > than 3.5 mm as well as duplex evidence of high volume and prolonged outward flow may indicate an IPV with significant pathophysiology.”
O’Donnell, T.Role of perforators in chronic venous insufficiency.
Phlebology 2010;25:3-10
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Courtesy: Nicos Labropoulos
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Lower calf posterolateral PV
Courtesy: Nicos Labropoulos
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Midthigh medial PV reflux
Courtesy: Nicos Labropoulos
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Pathologic vs. Incompetent(Perforators, Not People)
≥ 3.5 mm
Reflux ≥ 0.5 secs.
C5 – C6 patients
IPV under or in proximity of ulcer
Incompetent – as above but < C5 pts.
SVS/AVF Clinical Practice Guidelines for Management of
Varicose Veins. In Press J Vasc Surg
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If You Do Believe (I Do Sometimes)
SEPS – Subfascial Endoscopic Perforator
Surgery
PAPS – Percutaneous Ablation of
PerforatorS
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SEPS/PAPS: Indications
CEAP 5,6
CEAP 2 or 3 - if source of VV (thigh) or pain
After GSV treatment or same time?
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SEPS
1990’s
Remote incisions
Endoscopic visualization
Subfascial ligation – clips, harmonic scalpel
Outpatient
Regional/General anesthesia
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Anatomy of Lower Leg
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Endoscopic InstrumentationAnd Surgical Techniques
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SEPS TechniquesDirect Subfascial
Visualization
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SEPS Advantages
Remote incisions -low wound complications
Visualize pathology
Identify more IPVs than pre op (2-3)
How do you know they’re IPVs?
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SEPS Disadvantages
Distal IPVs
Swordfighting
Learning curve
General/Regional anesthesia
ASC or OR setting
Frustration and incomplete exploration
Low adaptation rate by surgeons
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Perforator Location Above Medial
Malleolus 25 Patients(72 IPVs)
0 – 5 cms. 24
6 – 10 cms. 24
11-15 cms. 10
Greater than 15 cms. 14
66% (48/72) within 10 cms of medial malleolus
Average = 2.9 IPVs per patient
Elias,S. Single-port SEPS: Less is more. AVF Annual Meeting 2005.
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Endoscopic InstrumentationAnd Surgical Techniques
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Single Port Scope
Elias,S.Single port SEPS:Less is more. AVF Feb. 2005
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New Concept - PAPS
Percutaneous
Ablation
PerforatorS
Will PAPS replace SEPS?
Elias S. Will SEPS Be Around in 5 Years?, IVC Apr. 2005, Miami FL.
Elias S. The New Perforator Algorithm,IVC Apr. 2006, Miami FL.
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PAPS: A Better Way
Percutaneous – No incisions
Ultrasound guided access
Local anesthesia
Office based
Easily repeatable
Elias,S. Will SEPS be around in 5 years? IVC Apr. 2005; Miami Fl
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PAPS Choices
Radiofrequency -TRLOP
Laser
Liquid/Foam
MOCA
Natural extension of EVA GSV/SSV
Enough energy to destroy vein
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PAPS Radiofrequency Catheters
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PAPS Laser Kit
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PAPS Laser Kit Features
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PAPS ACCESS
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PAPS: ACCESS
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PAPS:MOCA
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Pre op IPV Duplex
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Percutaneous USG Access
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Post PAPS Changes - US
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Post PAPS Changes - Duplex
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Post SEPS Clipping
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Pre and Post PAPS
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EHMC Technique
Access – RFS, 21 g. needle, 16g. angiocath
Location – just below fascia and above
Treat – 2-3 segments approx. 1-2 mm apart
RF - 85 C, 60sec/quadrant, 4min,12min total
Laser – Pulsed 5 sec/15 W, 75 joules, 225 joules total
Compression – 1 min with probe
Post Rx – Confirm occlusion, deep flow
Follow up – Eccentric wrap 48hr, stocking 2 wks.
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EHMC Center for Vein Disease
Total pts. - 31
CEAP 4 - 8
CEAP 5 - 5
CEAP 6 - 18
Total IPVs - 50
Avg/pt - 1.6
Avg size - 4.8mm
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EHMC Overall (RF and Laser)
100% procedure success
88% closed @ 3 months (42/48)*
89% ulcer healing at 6 weeks (16/18)
* Excluding 2 undertreated IPV
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EHMC Complications
Nerve injury – 0%
Vascular injury – 0%
Hematoma – 1/50 (2%)
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Results Others – USG Sclero
3% STD liquid
.5-1 cc/IPV
Compression 4 weeks
85% occlusion at 6 months
No DVT/skin/nerve injury
*Thibault PK et al.Recurrent varicose veins.Part2:injection of
Incompetent perforating veins using ultrasound guidance.
J Dermatol Surg Oncol.1992:18:895-900
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Results Others – USG Sclero
Sodium morrhuate 5% liquid
80 pts.
98% initial success
75% closed at 20 months
No skin/nerve injury
*Masuda EM et al.The effect of ultrasound guided sclerotherapy
Of incompetent perforating veins on venous clinical severity and
Disability scores.J Vasc Surg 2006;43:551-7.
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Results Others - RF
Lumsden - 91% closed @3 months(SCVS 05)
Chang - 87% reflux free @ 6 mo.
-91% reflux free @ 12 mo. (VEITH 2006)
Murphy - 90% closed @ 6 mo. (ACP 2006)
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Results Others - Laser
Kabnick - 85% closed @ 4 mo. (InVein 2006)
Murphy - 100% closed @ 6 mo. (ACP2006)
Proebstle - 100% closed @ 48hrs.(50 IPVs)
- 100% closed @ 4 mo.(17 only) -C2 pts.
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Recent Reports 1 yr. – 82% closed
Treated truncal first and then IPV after only 1 week
“Perforator incompetence was present if any outward flow was present with color…All IPVs were treated regardless of diameter.”
“We treated all IPVs as part of our treatment plan regardless of VCSS or symptoms”
Marsh,P et al. 1 yr. outcomes of RFA of IPVs using RF stylet device.
Phlebology 2010;25:79-84
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The Treachery of Images: Whiteley Group Cont.
“IPV’s were re-identified intaop using DUS….
“But we did not routinely reasses competence of IPVs at this stage after treatment of truncal reflux” (only 1 week before)
“Diameter of IPV’s was not measured preop..so can’t comment on effect of tx”
Endpoints – Closure only? Treating the image?
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PAPS Results: Summary*
80% - 90% early closure 3 – 6 – 12 months
Access with experience 100%
Minimal morbidity
Technically harder than EVA GSV/SSV
Too many C2 patients done
Short term F/U only and most address ablation only**
*Elias,S. Peden,E. Ultrasound-guided percutaneous ablation for the
treatment of perforating vein incompetence. Vascular 2007;15:281-9
**Bacon, JL et al. Five year results of perforator vein closure using
Trans-Luminal Occlusion of Perforator. Phlebology 2009;24:74-8.
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The Big Problem: 2C*No EBM for IPV Rx
Dutch SEPS Trial
ESCHAR Study
Minimal follow up > 1 year
The end is near unless…..
Clinical Trials - isolate IPV’s
*Elias, S. Percutaneous Ablation of Perforators. Handbook of Venous
Disorders 3rd ed. (Gloviczki, P. ed.), 2009.
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Clinical Trials
Isolate IPV’s –Superficial/Deep issues
Endpoints - recurrence not healing
Endpoints - recurrence not ablation
Define pathologic PV in trials/reports
Candidates - C5 & C6
Not C2 patients - let’s be realistic
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DSM IV: Criteria
Personality Type - normal variant
Personality Disorder – pathologic
Incompetent person≠ Pathologic person
Pathologic person= Incompetent person
Incompetent Perf ≠ Pathologic Perf
Pathologic Perf = Incompetent Perf
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Pathologic vs. Incompetent(Perforators, Not People)
≥ 3.5 mm
Reflux ≥ 0.5 secs.
C5 – C6 patients
IPV under or in proximity of ulcer
Incompetent – as above but < C5 pts.
SVS/AVF Clinical Practice Guidelines for Management of
Varicose Veins. In Press J Vasc Surg
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Why does a dog lick himself ?Because he can
Just because we can do it
Doesn’t mean we should do it
Even if it is fun (PAPS)
Insurance is correctly questioning
Without facts we look like fools
Prove it or forget it
If not……The End Is Near
![Page 54: Perforator Vein Treatment - The Venous · PDF filePerforator Vein Treatment: You can’t tell people what they want to hear If you also want to tell them the truth* Steve Elias MD](https://reader034.vdocuments.site/reader034/viewer/2022042708/5a78f30b7f8b9a83238ed57e/html5/thumbnails/54.jpg)
The End: Treat the Right Patient
Not The Image
The Treachery of Images, Rene Magritte