patogenesis radang pada organ mata
TRANSCRIPT
-
7/27/2019 Patogenesis Radang Pada Organ Mata
1/13
-
7/27/2019 Patogenesis Radang Pada Organ Mata
2/13
-
7/27/2019 Patogenesis Radang Pada Organ Mata
3/13
Clinical Manifestation of Eye Disease
Pain : - many different types
- conjunctival / corneal : associated with itching, burning +photophobia
- >> : glaucoma
Visual Disturbances- decreased visual aquity (amblyopia)
- spots / halos : cataract / glaucoma- diplopia : eye muscle disfunction
Discharge- increasing tearing ( eg. : allergic)
- microscopic : inflam.cells / viral or chlamydial inclusions
Change in Appearance :
strabismus (muscle imbalance), hemorrhage, congestion, jaundice,
swelling, displacement (eg.proptosis), tumors
-
7/27/2019 Patogenesis Radang Pada Organ Mata
4/13
The Eye Lid
Blepharitis : low grade inflammation
Hordeolum- acute suppurative inflam. of hair folicle : + sebaceous glands (Zeis) +
+ apocrine glands ( Moll)
- caused by Staph. aureus
-
7/27/2019 Patogenesis Radang Pada Organ Mata
5/13
Chalazion
- involving meibomian glands
- cause by duct obstruction :- leading to retention of secretions
infection
chronic inflam.
( macrophages,
lymphocyte,
plasma cells)
- produces mass :
mistaken for a neoplasm
-
7/27/2019 Patogenesis Radang Pada Organ Mata
6/13
The Conjunctiva & Cornea
Keratoconjunctivitis-inflam. of conjunctiva : conj.tis
-Inflam.of the cornea : keratitis
-frequently both involve : keratoconj.tis
Acute Bacterial Conj.tis- pain, hyperemia (vascular injection) :red eye,
- discharge (neutrophils)
- common : Neisseria, pneumococcus, Haemophilus aegyptus
- severe cases : ulceration, involves cornea : visual impairment
Opthalmia Neonatorum : infection of the fetus w/ N. gonorrhoeaeduring delivery through the birth canal
-
7/27/2019 Patogenesis Radang Pada Organ Mata
7/13
Red eye ; OS>OD
Crusting on the lashes
Conjunctival injection with a follicular
conjunctivitis.
-
7/27/2019 Patogenesis Radang Pada Organ Mata
8/13
Ciliary flush along the corneal limbus.
Follicles on the palpebral conjunctivae
-
7/27/2019 Patogenesis Radang Pada Organ Mata
9/13
Viral Conj.tis: adenoviruses / herpes simplex virus
Inclusion Conj.tis- swimming pool conj.tis
- acute inflam. With pain, red eye, discharge
- histologically : accum.of lymphocyte in conj.
- caused by Chlamydiae : cytoplasmic inclusions in infected cells
in the exudate
- transmited : contaminated hands, shared towels, fetus by infected
birth canal
- self-limited : after few days
Corneal scar by recurent
herpes simplex keratitis
-
7/27/2019 Patogenesis Radang Pada Organ Mata
10/13
Trachoma- serious Chlamydial infection
- long term destruction of the cornea
- non early treated : blindness
- acute inflam. progress to chronicepithelial hyperplasia + lymphocytic infiltration
+ pannus formation inflammed mass of granulation tissue
replaced superficial layers of the cornea blindness
Acanthamoeba Keratoconj.tis- caused by amoeba :Acanthamoeba, contaminated lens cleaning fluids
Allergic Conj.tis- vernal / spring conj.tis
- typically seasonal- + hay fever
- hstpl : goblet cell hyperplasia, lymphocyte and eosinophils infiltration
-
7/27/2019 Patogenesis Radang Pada Organ Mata
11/13
PhlyctenularConj.tis
- delayed hypersensitivity response to Ag bacteria ( M.tuberculosis, S.aureus)
- elevated, hard, red triangular plaque at the limbus ulcerate
heals
( 2 weeks)
-
7/27/2019 Patogenesis Radang Pada Organ Mata
12/13
The Eye Ball
Bacterial Infection- pyogenic bacteria (staph) :entry the eye ball by :
> penetrating injuries
> orbital cellulitis
> blood stream
- endophtalmitis or panophtalmitis
Toxoplasma Chorioretinitis
- Toxoplasma gondii choroid and retina
- Congenital or Acquired- hstpl : focal coagulative necrosis of retina / choroid + granulamatous
inflam. + fibrosis
Toxoplasma : crescent-shapes trophozoites / larger pseudocyst
-
7/27/2019 Patogenesis Radang Pada Organ Mata
13/13