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The potential of research in the Centre for Brain Research to advance research in Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons Research - 28 May 2019

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Page 1: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

The potential of research in the

Centre for Brain Research

to advance research in

Parkinson’s Disease

Richard Faull

Director

Centre for Brain Research

The University of Auckland

The Science of Parkinsons: Advances in Parkinsons Research - 28 May 2019

Page 2: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

Centre for Brain Research, University of Auckland

Promote collaborative research

Research Community Clinical

Page 3: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

Brain Research at The University of Auckland

• 84 different research groups across the

University

– Neuropathology & Clinical neuroscience

– Cognitive Neuroscience & Neuropsychology

– Molecular, Cellular, Genetic Neuroscience

– Sensory and Motor Neuroscience

• More than 450 researchers in the Centre

Page 4: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

Clinical Research at the Auckland

Hospitals

• Neurologists

• Neurosurgeons

• Neuropsychologists

• Neuroradiologists

• Geriatricians

• Psychiatrists

• Neuropathologists

• Develop New Treatments & Science

– Deep brain stimulation (PD)

– Choroid Plexus Transplants for PD

– Neurosurgical biopsies – grow brain cells

Page 5: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

Community Partners

• Parkinsons New Zealand• Parkinsons Auckland• Alzheimers New Zealand• Dementia Auckland • Epilepsy New Zealand • Huntington’s Disease Association • Motor Neurone Disease Association of New Zealand • Multiple Sclerosis Society of Auckland • Multiple Sclerosis Society of New Zealand • Muscular Dystrophy Association of New Zealand • Stroke Foundation of New Zealand • Stroke Foundation Northern Region

Page 6: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons
Page 7: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons
Page 8: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

The Neurological Foundation of NZ

Human Brain Bank – Established in 1994

Huntington’s Disease

Parkinson’s Disease

Alzheimer’s Disease

Epilepsy

Motor Neuron Disease

Multiple Sclerosis

Glioblastoma tumoursSUPPORTED BY:

- Alzheimers New Zealand

- Dementia New Zealand

- Parkinsons New Zealand

- Huntington’s Disease Association

- Epilepsy Association of New Zealand

- Motor Neuron Disease Association of New Zealand

Page 9: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

The Neurological Foundation Human Brain Bank:

A World-Class Resource–Centre for Brain Research

Page 10: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

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• Up to 120 blocks per brain

• Tissue from >1000 brains

• 45,000+ blocks in storage

Page 11: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

Dissection Dicing

Digestion

Cell

cultureExperiments

and

Analysis

Culture human brain cells

Page 12: Parkinson’s Disease - PD... · Parkinson’s Disease Richard Faull Director Centre for Brain Research The University of Auckland The Science of Parkinsons: Advances in Parkinsons

Team Collaboration is the key to

World Class Rresearch

Science is about people