the LENT-SOMA scale and the scoring system described by Phulpin.Assessments were performed pre-operatively and at 3 months.

It is anticipated that treatment will require three installations,3 months apart and assessments will be repeated to a 2 year end-point.

Results: The study is still recruiting and we present the early re-sults of the index cases. There were no donor site complications.There was improvement in all measured indices and reportedimprovement in subjective measures such as pain and Quality of Lifescores.

Summary: This is a low morbidity procedure which has provenutility in other sites. The early results support its continued usewithin the determined criteria and may offer a therapeutic solutionto other cicatrical or ischaemic problems in post burns or trauma.

doi:10.1016/j.oraloncology.2011.06.443

P201. The change of C-Reactive Protein in oral cancer patientsafter resection and reconstructive surgeryC.-H. Kim, C.-H. Lee, S.-I. Han *

Dankook University, Republic of Korea

Purpose: The aim of this study is that we evaluate the change ofthe White Blood Cell (WBC) count, Absolute Neutrophil Count (ANC),Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP)values, and try to make standardization for postoperative sequels be-fore and after the oral cancer resection and reconstructive surgery.

Materials and methods: The study was comprised of 34 patients(male 15, female 19) who were diagnosed as an oral cancer and hadperformed ablation and reconstructive surgery at Dankook univer-sity dental hospital. Each blood specimen was collected from pa-tients and estimated WBC count, Neutrophil count, ESR, CRP onfirst, third, fifth, seventh day before and after surgery and analyzinginter relationship between each value. Classifying Group I (resectionwith reconstructive surgery patients) and Group II (resection with-out reconstructive surgery patients). Also classifying Group A (below4 h of operation time), Group B (4–8 h of operation time), Group C(above 8 h of operation time), each group was analyzed and com-pared. The Following results were induced.

Results:

1. In coefficient of correlation, the CRP and WBC has highest valueexcept WBC count and Neutrophil count.

2. There was no significant difference any lapse in the progressbetween Group I and II of WBC count, Neutrophil count, but theCRP shows statistically higher level in Group I than Group II atimmediate postoperative day, and 1–5 days after surgery.

3. There is no significant difference any lapse in the progressbetween Group A, B, C of WBC count, Neutrophil count, but CRPshows statistically significant difference in 1 day, 3 days aftersurgery

Conclusion: It should be suggested that, determination of CRP ismost valuable parameter for postoperative management and deter-mination of postoperative clinical changes than other parametersuch as WBC count, Neutrophil count, and ESR values in oral cancerpatient after resection and reconstructive surgery, based on the re-sults of this study.

doi:10.1016/j.oraloncology.2011.06.444

P202. Submental island flap for reconstruction of oral cavity andoropharynxS. Song*, Y. Kim, C. Bae, S. Ye, B. Jeon

Yeungnam University Medical Center, Republic of Korea

Introduction: Variable flaps are using for reconstruction afterhead and neck tumor surgery. The submental island flap whichwas introduced by Martin et al. (1993) is a variation of platysmamyocutaneous flap. It was used for variable defect after head andneck surgery. We performed this study to evaluate the usefulness,reliability, donor site morbidity, oncological safety and complicationof the submental island flap in oral and oropharyngeal cancer.

Methods: Nine cases of oral and oropharyngeal cancer were en-rolled this study. We reviewed patients’ medical records retrospec-tively. Primary sites were two cases of palatine tonsil, three casesof mouth floor, two cases of mobile tongue, a case of buccal mucosaand a case of lateral pharyngeal wall. Defects were reconstructedwith the submental island flap in all cases.

Results: Reconstructions of defect performed transorally in eightcases and through lower cheek flap in a case. It takes only 1 h to ele-vate the submental flap. There was no need to microscopic vascularanastomosis, so total needed time for reconstruction using submen-tal island flap was much shorter than that for reconstruction usingfree flap. Tracheotomy was made in five cases and removed withoutany difficulties in all case within a week. Total flap loss was occurredin first case having mouth floor cancer who was previously treatedwith concurrent chemoradiation for soft palate cancer of contralat-eral side. There was no recurrence in transferred flap or morbidityof donor site. Transient facial palsy was developed in a case, andintractable hair growth was found in a case. Debulking operationwas done in two cases of mouth floor cancer.

Discussion: The submental island flap is very useful and oncolog-ically safe reconstructive method for defect of oral cavity and oro-pharynx. Submental island flap can be performed by head andneck surgeon himself and can be made in same field with main pro-cedure. So, we concluded that the submental island flap can be usedfor excellent variable for reconstruction in oral cavity and oropha-ryngeal cancer surgery.

doi:10.1016/j.oraloncology.2011.06.445

P203. Reconstruction of post oncological tongue defectsS. Selva Seetha Raman*, S. Praba Yadav, S. Vinay Kant, J. Dushyant,S. Nitin, N.S. Bheem

Tata Memorial Hospital, India

Introduction: Carcinoma tongue is one of the most commonmalignancies in the developing countries and surgery is the primarymodality of management. The reconstruction of such tongue defectsshould aim at providing good speech, bulk, mobility and preventionof aspiration.

Methods: We present the cases of post oncological tongue de-fects reconstructed by using both pedicled and free flaps, done inour institute in the past 5 years. We have done Pectoralis MajorMyocutaneous flap, Pectoralis Major muscle flap, Free Radial ArteryForearm Flap, Free Anterolateral Thigh Flap depending upon the per-centage of remaining tongue, the presence of tissue in the floor ofmouth and the patient conditions.

Results: Free Radial Artery Forearm Flaps gives the best func-tional result when the tongue excision is between 20% and 80%and the floor of mouth is intact. Anterolateral thigh flap gives the

Abstracts / Oral Oncology 47 (2011) S74–S156 S139