2004 Carboxylic acids

Carboxylic acidsQ 0420 Oxidation of Toluenes to Benzoic Acids by Oxygen in Non-acidic Solvents. —

A new, practical procedure for the oxidation of substituted toluenes with molecular oxygen under atmospheric pressure in non-acid solvents such as dichlorobenzene, chlo-robenzene and bromobenzene using Co(C18H35O2)2/NH4Br or Co(OAc)2/NaBr/AcOH as catalyst in the presence of a radical initiator is described. The oxidation works well both with electron-withdrawing and electron-donating substituted toluenes. — (YANG, F.; SUN, J.; ZHENG, R.; QIU, W.; TANG*, J.; HE, M.; Tetrahedron 60 (2004) 5, 1225-1228; Dep. Chem., East China Norm. Univ., Shanghai 200062, Peop. Rep. China; Eng.) — Bartels

24- 088