onsite hbsag /hcv ab rapid test detects hbv and hcv infection in 1 run
TRANSCRIPT
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OnSite HBsAg /HCV Ab Rapid Test
Detects HBV and HCV Infection in 1 run
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Facts of HBV and HCV Infection
• Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are the two most common blood born infectious agents. – About 5% of world population has chronic HBV infection – More than 3% world population is infected by HCV – HCV and HBsAg is often co-infected
• Infected person or asymptomatic carries with HBV and HCV are only reservoir of infection.
• Prompt identification of carries is the key to prevent from HBV and HCV transmission.
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Indication of HBsAg and HCV Ab Testing
• Blood donor screening • Preparation test before surgery • Hepatitis diagnosis
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HBsAg Is The Marker Of HBV Infection
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HCV Antibodies Is The Marker Of HCV Infection
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Current HBV & HCV Testing Procedure
HBsAg Rapid Test HBsAg ELISA Test HBV PCR Test
HCV Ab Rapid Test HCV Ab ELISA Test HCV PCR Test
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A New Cost Effective Test by CTK
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OnSite HBsAg/HCV Ab Test Procedure
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Result Demonstration
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OnSite HBsAg/HCV Ab Rapid Test Performance
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Equivalent Sensitivity To The Individual HBsAg And HCV Ab Rapid Tests
Specimens HBsAg positive HCV Ab positive
Tests 1:100 1:200 1:10 1:50
HBsAg > + + N/A
HCV Ab N/A N/A ++ +
HBsAg/HCVLot#1
> + + ++ +
HBsAg/HCVLot#2
> + + ++ +
HBsAg/HCVLot#3
> + + ++ +
Detection Level for HBsAg: As low as 0.5 ng/ml
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Performance on clinical specimens
HBsAg/HCV Ab Rapid Test
HCV Ab ELISA Positive Negative Total
Positive 45 0 45
Negative 4 450 454
Total 49 450 499
HBsAg/HCV Ab Rapid Test
HBsAg ELISA Positive Negative Total
Positive 97 0 97
Negative 0 463 463
Total 97 463 560
Relative Sensitivity: 100%, Relative Specificity: 99.1%, Overall Agreement: 99.2%
Detection of HCV
Detection of HBsAg
Relative Sensitivity: 100%, Relative Specificity: 100%, Overall Agreement: 100%
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Highly Specific
No false positive result on
200 frozen random serum specimens 50 fresh random clinical specimens
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No Inferenced By Common Chemicals HBsAg Detection HCV Ab Detection
Control Strong Weak Neg. Strong Weak Neg. Birubin 20mg/dl ++ + - ++ + -
6.7mg/dl ++ + - ++ + -Creatin 442µmol/l ++ + - ++ + -
++ + - ++ + -Glucose 55mmol/l ++ + - ++ + -
++ + - ++ + -Salicylic acid
4.34 mM ++ + - ++ + -1.45 mM ++ + - ++ + -
Heparin 3 U/ml ++ + - ++ + -1 U/ml ++ + - ++ + -
EDTA 3.4uM ++ + - ++ + -1.1uM ++ + - ++ + -
Human IgG
1 g /dl ++ + - ++ + -0.3g/dl ++ + - ++ + -
Citriate sodium
3.8% ++ + - ++ + -1.27% ++ + - ++ + -
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No Cross-Reactivity with Hyper Immune Specimens
ANA specimens KB61155 KB64917 KB77964 KB77335 KB80040 KB8008
HBsAg/HCV Lot#1 Negative Negative Negative Negative Negative Negative
HBsAg/HCV Lot#2 Negative Negative Negative Negative Negative Negative
HBsAg/HCV Lot#3 Negative Negative Negative Negative Negative Negative
RF specimens 22 IU/ml 294 IU/ml 2515 IU/ml
HBsAg/HCV Lot#1 Negative Negative Negative
HBsAg/HCV Lot#2 Negative Negative Negative
HBsAg/HCV Lot#3 Negative Negative Negative
HAMA specimens SD3145 SD3135 SD3139 SD3158
HBsAg/HCV Lot#1 Negative Negative Negative Negative
HBsAg/HCV Lot#2 Negative Negative Negative Negative
HBsAg/HCV Lot#3 Negative Negative Negative Negative
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Not Cross-Reactivity With Common Infectious Diseases
Diseases Dengue HAV HIV Syphilis TB H. plyloriHBsAg/HCV Lot#1 Negative Negative Negative Negative Negative Negative
HBsAg/HCV Lot#2 Negative Negative Negative Negative Negative Negative
HBsAg/HCV Lot#3 Negative Negative Negative Negative Negative Negative
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OnSite: The practical advantages -DRUQ
Detection Advantages Detects HBsAg and HCV Ab in 1 test run Easily accessible specimens serum, plasma, whole blood, suitable for emergency care
Result Advantages HBV and HCV infection within 15 minutes, enabling doctor to take immediate action Highly accurate & reproducible
User Advantages One test procedure for 2 test results Save specimen, reduce work load, and reduce cost!
Quality Advantages Equivalent performance to the individual HBsAg and HCV Ab Rapid Test
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Final Message to Doctors
To reduce cost and work load Order
Onsite HBsAg / HCV Ab Rapid Test
Also available of OnSite HIV/Syphilis Ab Rapid Test
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For further information about OnSite HBsAg / HAV Ab Rapid Test kits
Exclusive distributor in Pakistan
[email protected] [email protected]@ctkbiotech.com San Diego, CA 92121, USA
CTK contact information:
Offices in:
Faisalabad Islamabad LahoreKarachiPrewash