oncogenic intelligence: cell immortalization and transformation by the p53 gene

2

' Nature Publishing Group 1984

Upload: dp

Post on 21-Jul-2016

213 views

Category:

Documents

0 download

Report

Download

Embed Size (px):

TRANSCRIPT

Page 1: Oncogenic intelligence: Cell immortalization and transformation by the p53 gene

© Nature Publishing Group1984

Page 2: Oncogenic intelligence: Cell immortalization and transformation by the p53 gene

© Nature Publishing Group1984

Novocastra Lyophilized Rabbit Polyclonal Antibody p53 ... · NCL-p53-CM1 Page 2 Novocastra TM Lyophilized Rabbit Polyclonal Antibody p53 Protein (CM1) Product Code: NCL-p53-CM1 Intended

Oncogenic virus ppt

Regulation of gene expression by mutant and oncogenic forms of the p53 tumor suppressor

The MDM2/MDMX-p53 Antagonist PM2 Radiosensitizes Wild … · performed on 3D multicellular tumor spheroids, using wt p53, p53, and mutant p53 cancer cells as described in the/ Supplementary

Oncogenic virus-host cell interaction

Isolation, immortalization, and characterization of a human ...publicationslist.org/data/rene.villadsen/ref-4/Gudjonsson...Isolation, immortalization, and characterization of a human

Regulation of autophagy by cytoplasmic p53 - … · Regulation of autophagy by cytoplasmic p53 ... p53 was able to repress the enhanced autophagy of p53–/ ... 4Università degli

Immortalization of Human Lymphocytes by Fusion with Cytoplasts of

Evolutionary Action Score of TP53 Identi High-Risk ...high-risk TP53 alterations. These oncogenic p53 mutations also had a distinct mRNA expression proﬁle, which suggests high-risk

Control of Nucleotide Metabolism Enables Mutant p53’s ...€¦ · Keywords: p53; nucleotide metabolism; GOFs; ETS2 1. Mutant p53’s Oncogenic Gain-of-Function TP53, a gene which

Oncogenic Stress Sensed by The

1 Molecular Biology of Cancer Eternal Life: Cell Immortalization and Tumorigenesis

Oncogenic risks in ART

Telomerase, Immortalization and Cancer Eric Bankaitis Cancer Bio 169 March 9, 2006

Immortalization of primary microglia: a new platform to ... · Immortalization of primary microglia: a new platform to study HIVregulation in the central nervous system Yoelvis Garcia-Mesa1

p53 Total and p53 (Phospho-Ser392 Dual Staining …gene, a significant proportion of them have inactivated p53 by alternative mechanisms.2 These characteristics make p53 a useful biomarker

05.04.09(b): Oncogenic Viruses

ZBTB2,aNovelMasterRegulatorofthep53Pathway S · tial proto-oncogenic master control gene of the p53 pathway and, in particular, is a potent transcription repressor of the cell cycle

p53 alteration is a common event in the spontaneous ...genesdev.cshlp.org/content/5/12b/2375.full.pdf · p53 alteration is a common event in the spontaneous immortalization of primary

The p53 target Wig-1 regulates p53 mRNA stability through ... › content › pnas › 106 › 37 › 15756.full.pdf · The p53 target Wig-1 regulates p53 mRNA stability through an

Oncogenic role of SFRP2 in p53-mutant osteosarcoma ...lDepartment of Pathology, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; mCenter for Stem Cell and Regenerative Medicine,

Senescence and immortalization

Oncogenic KRAS G12D mutation promotes dimerization …

Research Paper The Gain of Function of p53 Mutant p53S in ...The loss of wild type p53 tumor suppressive function and oncogenic gain-of-function of p53 mutants have been showing important

The Role of Apaf-1, Caspase-9, and Bid Proteins in Etoposide- or ... · Apaf-1 or caspase-9 has been shown to substitute for p53 loss in promoting oncogenic transformation of the

Rab35FunctionsinAxonElongationAreRegulatedby P53

ONCOGENIC DRIVERS OF CUTANEOUS MALIGNANT MELANOMA …

of HPV16 in cervical lesions determined with the Luminex ... 4.pdf · oncogenic transformation, for which interaction of E6 and E7 with the tumor suppressor gene products p53 and

CELL TRANSFORMATION ONCOGENIC VIRUSES

Oncogenic KRAS and p53 Loss Drive Gastric Tumorigenesis ......Tumor and Stem Cell Biology Oncogenic KRAS and p53 Loss Drive Gastric Tumorigenesis in Mice That Can Be Attenuated by

Shifting perspectives from “oncogenic” to oncofetal

Immortalization eliminates a roadblock during cellular ...rheinwaldlab.bwh.harvard.edu/pdf/Utikal 2009 Nature, immort aids... · Immortalization eliminates a roadblock during cellular

Nano-Traps against p53-N-term, p53-C-term & Mdm4/ HdmX for ...€¦ · Nano-Traps against p53-N-term, p53-C-term & Mdm4/ HdmX for Immunoprecipitation Pulldown of the p53 proteome

Case Report Nasal Hemangiopericytoma Causing Oncogenic