Section Meeting Thursday 15 Nov 2012

EXPLOITING METABOLIC DIVERSITY FOR GENE DISCOVERY

Lloyd W. Sumner Plant Biology Division

Samuel Roberts Noble Foundation

The past decade has yielded highly sophisticated analytical instrumentation which now makes the large-scale biochemi-cal profiling of mRNA, proteins and metabolites possible. These technologies are routinely referred to as transcriptom-ics, proteomics and metabolomics. We are using integrated metabolomics and transcriptomics to obtain novel insight into legume natural product biosynthesis. Legumes are funda-mental sources of nutrition for most global cultures due to their high protein content achieved through unique symbioses with nitrogen-fixing bacteria. Legumes also produce a wide array of natural products including flavonoids, isoflavonoids, lignin, anthocyanins, and triterpene saponins. These com-pounds serve critical roles in plant defense, plant-microbe interactions, symbiosis, and human and animal health. This presentation will introduce the model legume Medicago trun-catula and provide an overview of our metabolomics technol-

NEWSLETTEROklahoma Section

American Chemical Society Volume 18 Number 5 http://oklahoma.sites.acs.org/ November 2012

Buffet Menu BBQ chicken breast sliced BBQ beef seasoned green beans potato salad, coleslaw rolls & butter, iced tea chocolate cake

Cost $15 members $5 students RSVP Deadline

Friday 02 Nov 5 pm Contact: Donna Nelson

405-325-2288 djnelson@ou.edu

RSVP is NOT required to attend the presentation.

Dinner Reservation Information

Oklahoma School of Science and Math library/administration building 1141 N Lincoln Blvd, Oklahoma City, OK 73104

5:30–6:30 pm Social Hour & Campus Tours 6:40–7:20 pm Dinner 7:30–9:00 pm Presentation

map & info: http://www.ossm.edu/

continued on page 2 with the speaker’s biographical sketch. →

OSSM map & directions

OK ACS SECTION ELECTIONS Ballot in this Newsletter

Cast Ballots due on or before 16 Nov

Nathan Malmberg has served as our section’s Chemistry Olympiad Coordinator since 2008. After 4 years of service, he would like to pass the responsibilities on to the next per-son. Filling his shoes can seem like a daunting task. Howev-er he is willing to work with the new coordinator for a season or two to make the transition smooth and painless.

Each year, the Chemistry Olympiad involves 100–120 stu-dents from 5–6 schools. We are always looking for new schools to participate.

The responsibilities of the coordinator are spread out across the season. To give you an idea of the scope of the work, Malmberg has provided the timeline below.

October to January: Contact area high school teachers inviting them to participate in the Chemistry Olympiad.

January: Order exams for the local section competition.

February: Send out exams and registration forms to high school teachers to administer the local section exam.

March: High school teachers administer exams and return answer sheets to the coordinator.

April: The coordinator grades the local exams, invites top

continued on page 2, Coordinator Wanted. →

Chemistry Olympiad

Coordinator Wanted

N e w s l e t t e r November 2012 Oklahoma Section ACS

— 2 —

ogies. The presentation will also provide specific exam-ples of how we are exploiting integrated metabolomics and metabolic diversity for the discovery and characteri-zation of triteprene saponin biosynthetic genes. This presentation also illustrates how cross discipline training provides for real world discoveries.

Lloyd W. Sumner Biographical Sketch

Dr. Sumner acquired his B.Sc. degree in chemistry and mathematics in 1989 from Cameron University in Law-ton, OK, USA and a Ph.D. in analytical chemistry in 1993 from Oklahoma State University in Stillwater, OK, USA. He then joined Texas A&M University, College Station TX, where he was the Director of the Mass Spectrometry Applications Laboratory and where he later served as the cofounder and Associate Director of the TAMU La-boratory for Biological Mass Spectrometry with Prof. Da-vid H Russell. He joined The Noble Foundation in 1999 and has risen to the rank of Professor within the Plant Biology Division. While at the Noble Foundation, Dr. Sumner has built a research program focused around the development and integration of large-scale biochemi-cal profiling of plant metabolites, proteins, and tran-scripts (metabolomics, proteomics and transcriptomics) for the discovery and characterization of the molecular and biochemical components related to plant natural products biosynthesis. He also applies these integrated omics technologies for greater insight into the physiologi-cal and biochemical consequences of gene expression and system responses to genetic and environmental per-turbations. In the process, he has published close to 100 peer reviewed articles and book chapters. Dr. Sumner’s research is supported by The Samuel Roberts Noble Foundation, The NSF 2010, NSF Molecular and Cellular Biosciences, the NSF Major Research Instrumentation program, NSF-JST joint Metabolomics, and The Oklaho-ma Commission for the Advancement of Science and Technology. Dr. Sumner is currently a Fellow of The American Association for the Advancement of Science, current Treasurer and past President of the Metabolom-ics Society, Co- founding Member of the International Advisory Committee for Plant Metabolomics, Adjunct Professor at Oklahoma State University Department of Biochemistry and Molecular Biology, and a Distinguished Alumni of Cameron University. Dr. Sumner serves as a Managing Editor for Plant Physiology and as an Editorial Board member for the journal Metabolomics.

(Coordinator Wanted—continued from front page) (Speaker—continued from front page)

CHEMISTRY OLYMPIAD • March 1–31 — Local Section Competitions • April 11–15 — National Exam (exact date TBA) • June 4–19 — Study Camp • July 15–24 — 45th IChO Moscow, Russia Contact Nathan Malmberg for more information nathan.malmberg@okbu.edu 405.878.2048

students to the national exam, procures materials for the lab portion of national exam, hosts & administers the national exam to the top students in the section, and then sends the exams to the national office to be graded.

May: The coordinator contacts any students who have been selected to participate in the study camp, prints certificates for students who participated in local exam.

Want to get involved? Contact Nathan Malmberg: nathan.malmberg@okbu.edu 405.878.2048

Give back to the community. Give Oklahoma students en-couragement to explore Chemistry as a field of study—and possibly a career.

Nathan Malmberg has been on the faculty at Oklahoma Bap-tist University since 2005. He earned his B.S. from University of Wyoming and his PhD from University of Colorado.

SWRM 2012 68th Southwest Regional Meeting

4–7 November 2012 Hosted by The Baton Rouge Section (Baton Rouge, LA)

http://www.swrm2012.org/

Does ACS have your current email address?

Quick facts • The Oklahoma section of the ACS membership is 534

• Only 502 of you have submitted email addresses to the ACS.

• Of the 502, approximately 19 addresses are undeliverable.

N e w s l e t t e r November 2012 Oklahoma Section ACS

— 3 —

Check out the OK section’s web site

http://oklahoma.sites.acs.org/

2011 Oklahoma ACS Section Officers and

Standing Committee Chairs Donna J. Nelson Chair Dane W. Scott Chair Elect Amanda J. Nichols Immediate Past Chair Lloyd A. Bumm Secretary + interim Newsletter ed. Jason Wickham Treasurer Allen Apblett Councilor + Nominations Com. Nicholas F. Materer Alternate Councilor Charles V. Rice Awards Com. Nathan Malmberg Chemistry Olympiad Com. Valerie Ferguson National Chemistry Week Com. Cheryl Frech Public Relations Jim Dechter Web Master

58TH ANNUAL PENTASECTIONAL MEETING Saturday 09 Mar 2013

Hosted by the Tulsa Section.

Symposium Session Topics Analytical Chemistry Chemical Education

Nanoscience Physical and Computational Chemistry

Organic and Biochemistry Environmental Chemistry

Biofuels and Green Chemistry Inorganic and Organometallic chemistry

Call for Abstracts

Send Abstract to Patrick Idwasi (pidwasi@tulsacc.edu) complete the abstract form and attach to your email. h p://tulsasec on.sites.acs.org/pentasec onal.htm

Pentasectional Web site

Oklahoma Chemist Award 2013 Call for Nominations Five (5) copies of a single nomination should be sent no later than 04 February 2013 to:

Dr. K. Darrell Berlin Chair, Oklahoma Chemist Awards Committee Department of Chemistry Oklahoma State University Stillwater, OK 74078 (405) 744-5950 kenneth.d.berlin@okstate.edu

Criteria and Guidelines for the Preparation of the Nomination and for Selection of the Recipient

1. A nomination letter for the candidate by a colleague, friend, etc.

2. A complete, up-to-date resume of the candidate. 3. A two-page "highlight" of the candidate's major accom-

plishments. 4. Five (5) letters of support for the nominee.

a) a) Two (2) letters from colleagues at the candidate's place of employment.

b) b) Three (3) letters from outside the candidate's place of employment.

Letters from individuals with expertise in the candidate's field are especially welcomed.

5. Special information on the candidate is also solicited, especially as to how the candidate has advanced chem-istry in the state of Oklahoma.

6. Candidates may be involved in research or in chemical education within the state.

WANTED CHEMISTRY OLYMPIAD COORDINATOR

Our section needs a volunteer to serve as the Chemistry Olympiad Coordinator. Nathan Malmberg has served dili-gently for several years. Unfortunately for us, he needs to step down. Thus a replacement is needed. Interested persons should contact: Nathan Malmberg Nathan.Malmberg@okbu.edu or Donna Nelson djnelson@ou.edu

NATIONAL CHEMISTRY WEEK 21–27 OCTOBER 2013 — Mark Your Calendars —

L. A. Bumm Oklahoma Section of the ACS Homer L Dodge Dept of Physics & Astronomy The University of Oklahoma 440 W Brooks St Norman, OK 73019-2061

Nonprofit Organization U.S. Postage Paid

The University of Oklahoma Norman, OK

Permit No. 88

Okl

aho

ma

AC

S C

alen

dar

of

Eve

nts

. V

isit

the

Okl

ahom

a A

CS

WW

W s

ite fo

r th

e la

test

info

rmat

ion.

ht

tp://

okla

hom

a.si

tes.

acs.

org/

2012

Dat

es &

Sp

eake

rs

No

v (4

-7)

SW

RM

201

2 B

aton

Rou

ge, L

A

No

v 15

(Th

u) O

SS

M, L

loyd

Sum

ner,

The

Sam

uel R

ober

ts N

obel

Fou

ndat

ion

Exp

loiti

ng m

etab

olic

div

ersi

ty fo

r ge

ne d

isco

very

2013

Ten

tativ

e D

ates

& S

pea

kers

Feb

12

(Tu

e) U

CO

, Don

na N

elso

n, D

epar

tmen

t of C

hem

istr

y, U

niv.

Okl

ahom

a

2013

Mar

09

(Sat

) 58

th P

enta

sect

iona

l Mee

ting,

hos

ted

by th

e T

ulsa

Sec

tion.

Ap

r 09

(Tu

e) O

C, C

huck

Gay

, Val

ero,

Ard

mor

e, O

K

May

02

(Th

u) O

SU

-OK

C, J

arra

d R

. Wag

ner,

For

ensi

c S

cien

ce, O

SU

Tul

sa

For

ensi

c T

oxic

olog

y an

d T

race

Che

mis

try

Sep

13

(Fri

) OB

U, D

r. J

im a

nd J

enny

Mar

shal

l, U

niv.

Nor

th T

exas

Oct

15

(Tu

e) T

BA

, Chu

nmin

g S

u, S

oil S

cien

tist,

Nat

iona

l NR

ML/

EP

S

No

v 14

(Th

u)

2019

Okl

ahom

a S

ectio

n C

ente

nnia

l

—

4 —

OK

ACS

web

Q

R co

de