oct in retinopathy of prematurity - livemedia.gr · b a r te s e lli g , d e ll'a r ti l , p...

OCT in Retinopathy of Prematurity

Susana Teixeira

Retina Department Ophthalmology Service Hospital Prof. Dr. Fernando Fonseca

28/01/2015 oct retina - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/?term=oct+retina 1/3

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Results: 1 to 20 of 14937

Peripapillary astrocytic hamartomas evolve from the optic nerve.

Saxena S, Meyer CH.

BMJ Case Rep. 2015 Jan 23;2015. pii: bcr2014207275. doi: 10.1136/bcr2014207275.

PMID: 25618878 [PubMed in process]

[Effect of nutrition on growth and neurodevelopment in the preterm infant: a systematic review].

Aguilar Cordero MJ, Sánchez López AM, Mur Villar N, Hermoso Rodríguez E, Latorre García J.

Nutr Hosp. 2014 Oct 31;31(2):71629. doi: 10.3305/nh.2015.31.2.8266. Spanish.

PMID: 25617555 [PubMed in process] Free Article

Complex I Subunit Gene Therapy with NDUFA6 Ameliorates Neurodegeneration in EAE.

Talla V, Koilkonda RD, Porciatti V, Chiodo VA, Boye SL, Hauswirth WW, Guy J.

Invest Ophthalmol Vis Sci. 2015 Jan 22. pii: IOVS1415950. doi: 10.1167/iovs.1415950. [Epub ahead of print]

PMID: 25613946 [PubMed as supplied by publisher]

Fluorescein angiography and optical coherence tomography in myopic choroidal neovascularization.

Chhablani J, Deepa MJ, Tyagi M, Narayanan R, Kozak I.

Eye (Lond). 2015 Jan 23. doi: 10.1038/eye.2014.345. [Epub ahead of print]


Longitudinal modifications of the Ozurdex intravitreal implant as imaged by SDOCT.

Barteselli G, Dell'Arti L, Pinna V, Ratiglia R, Viola F.

Eur J Ophthalmol. 2015 Jan 15:0. doi: 10.5301/ejo.5000551. [Epub ahead of print]


OPTICAL COHERENCE TOMOGRAPHYBASED POSITIONING REGIMEN FOR MACULAR HOLE

SURGERY.

Chow DR, Chaudhary KM.

Retina. 2015 Jan 19. [Epub ahead of print]


The effect of rebreathing and hyperventilation on retinal and choroidal vessels measured by spectral

domain optical coherence tomography.

Ozcimen M, Sakarya Y, Goktas S, Sakarya R, Alpfidan I, Yener HI, Demir LS.

Cutan Ocul Toxicol. 2015 Jan 19:15. [Epub ahead of print]


A prospective pilot study of intravitreal aflibercept for the treatment of chronic central serous

chorioretinopathy: the CONTAIN study.

Pitcher JD 3rd, Witkin AJ, DeCroos FC, Ho AC.

Br J Ophthalmol. 2015 Jan 16. pii: bjophthalmol2014306018. doi: 10.1136/bjophthalmol2014306018. [Epub ahead of print]

Summary 20 per page Sorted by Recently Added

PubMed oct retina

28/01/2015 oct glaucoma - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/?term=oct+glaucoma 1/3

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Validity of the temporaltonasal macular ganglion cellinner plexiform layer thickness ratio as a

diagnostic parameter in early glaucoma.

Park JW, Jung HH, Heo H, Park SW.

Acta Ophthalmol. 2015 Jan 25. doi: 10.1111/aos.12666. [Epub ahead of print]


Structural and functional changes in glaucoma: comparing the twoflash multifocal electroretinogram to

optical coherence tomography and visual fields.

Ledolter AA, Monhart M, Schoetzau A, Todorova MG, PalmowskiWolfe AM.

Doc Ophthalmol. 2015 Jan 24. [Epub ahead of print]


Dexamethasone Intravitreal Implant for Chronic Diabetic Macular Edema Resistant to Intravitreal

Bevacizumab Treatment.

Totan Y, Güler E, Gürağaç FB.

Curr Eye Res. 2015 Jan 22:17. [Epub ahead of print]


A joint estimation detection of Glaucoma progression in 3D spectral domain optical coherence

tomography optic nerve head images.

Belghith A, Bowd C, Weinreb RN, Zangwill LM.

Proc SPIE. 2014 Mar 18;9035:90350O.

PMID: 25606299 [PubMed] Free PMC Article

Assessing assumptions of a combined structurefunction index.

Swanson WH, Horner DG.

Ophthalmic Physiol Opt. 2015 Jan 21. doi: 10.1111/opo.12195. [Epub ahead of print]


New developments in optical coherence tomography.

Kostanyan T, Wollstein G, Schuman JS.

Curr Opin Ophthalmol. 2015 Jan 15. [Epub ahead of print]


Lamina Cribrosa Visibility using Optical Coherence Tomography: Comparison of Devices and Effects of

Image Enhancement Techniques.

Girard MJ, Tun TA, Husain R, Acharyya S, Haaland B, Wei X, Mari JM, Perera SA, Baskaran M, Aung T,

Strouthidis NG.

Invest Ophthalmol Vis Sci. 2015 Jan 15. pii: IOVS1414903. doi: 10.1167/iovs.1414903. [Epub ahead of print]



PubMed oct glaucoma

28/01/2015 oct cornea - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/?term=oct+cornea 1/3

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[Evaluation the change of corneal epithelium thickness after pterygium excision with conjunctival

autograft transplantation by Fourier domain optical coherence tomography].

Wu D, Hong J, Wang F, Cui X, Yang Y, Zhao Y, Xu J.

Zhonghua Yan Ke Za Zhi. 2014 Nov;50(11):8338. Chinese.


Fourierdomain optical coherence tomography imaging in corneal epithelial basement membrane

dystrophy: a structural analysis.

El Sanharawi M, Sandali O, Basli E, Bouheraoua N, Ameline B, Goemaere I, Georgeon C, Hamiche T,

Borderie V, Laroche L.

Am J Ophthalmol. 2015 Jan 8. pii: S00029394(15)000070. doi: 10.1016/j.ajo.2015.01.003. [Epub ahead of print]


[DSAEK after failed penetrating keratoplasty].

Zitte K, Bonnin N, Kémény JL, Bacin F, Mulliez A, Chiambaretta F.

J Fr Ophtalmol. 2015 Jan;38(1):2233. doi: 10.1016/j.jfo.2014.06.009. Epub 2015 Jan 6. French.


Disease progression in iridocorneal angle tissues of BMP2induced ocular hypertensive mice with optical

coherence tomography.

Li G, Farsiu S, Qiu J, Dixon A, Song C, McKinnon SJ, Yuan F, Gonzalez P, Stamer WD.

Mol Vis. 2014 Dec 20;20:1695709. eCollection 2014.

PMID: 25558173 [PubMed in process] Free PMC Article

Evaluation of the adhesive properties of the cornea by means of optical coherence tomography in

patients with meibomian gland dysfunction and lacrimal tear deficiency.

Napoli PE, Coronella F, Satta GM, Galantuomo MS, Fossarello M.

PLoS One. 2014 Dec 23;9(12):e115762. doi: 10.1371/journal.pone.0115762. eCollection 2014.

PMID: 25536051 [PubMed in process] Free PMC Article

[The clinical study of corneal crosslinking with hypoosmolar riboflavin solution in thin keratoconic

corneas].

Wu H, Luo S, Dong N, Lin Z, Liu Z, Shang X.

Zhonghua Yan Ke Za Zhi. 2014 Sep;50(9):6816. Chinese.


[The study of corneal epithelial change in keratoconic eyes with Fourierdomain optical coherence

tomographic pachymetry].

Zhao Y, Hong J, Wang F, Cui X, Yang Y, Zhu X, Wu D, Wei A, Chen Y, Wu S, Huang F, Xu J.

Zhonghua Yan Ke Za Zhi. 2014 Sep;50(9):66570. Chinese.



PubMed oct cornea 24/01/2015 optical coherence tomography and rop - PubMed - NCBI

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Understanding clinically undetected macular changes in early retinopathy of prematurity on spectral

domain optical coherence tomography.

Vinekar A, Avadhani K, Sivakumar M, Mahendradas P, Kurian M, Braganza S, Shetty R, Shetty BK.

Invest Ophthalmol Vis Sci. 2011 Jul 15;52(8):51838. doi: 10.1167/iovs.107155.

PMID: 21551410 [PubMed indexed for MEDLINE] Free Article

[Pattern retinal laser coagulation in treatment of aggressive posterior retinopathy of prematurity].

Tereshchenko AV, Belyĭ IuA, Volodin PL, Trifanenkova IG, Tereshchenkova MS.

Vestn Oftalmol. 2010 NovDec;126(6):3843. Russian.

PMID: 21395000 [PubMed indexed for MEDLINE]

Management of retinal vasoproliferative tumor associated with ROP by plaque brachytherapy.

Kitei PM, Say EA, Shields CL, Regillo CD, Shields JA.

J Pediatr Ophthalmol Strabismus. 2011 Feb 15;48 Online:e102. doi: 10.3928/019139132011020806.


Central macular thickness is correlated with gestational age at birth in prematurely born children.

Akerblom H, Larsson E, Eriksson U, Holmström G.

Br J Ophthalmol. 2011 Jun;95(6):799803. doi: 10.1136/bjo.2010.184747. Epub 2010 Oct 24.


Optical coherence tomography imaging of the fovea in retinopathy of prematurity.

Baker PS, Tasman W.

Ophthalmic Surg Lasers Imaging. 2010 MarApr;41(2):2016. doi: 10.3928/154288772010030308.


Retinoschisis detected with handheld spectraldomain optical coherence tomography in neonates with

advanced retinopathy of prematurity.

Muni RH, Kohly RP, Charonis AC, Lee TC.

Arch Ophthalmol. 2010 Jan;128(1):5762. doi: 10.1001/archophthalmol.2009.361.


Insights into advanced retinopathy of prematurity using handheld spectral domain optical coherence

tomography imaging.

Chavala SH, Farsiu S, Maldonado R, Wallace DK, Freedman SF, Toth CA.

Ophthalmology. 2009 Dec;116(12):244856. doi: 10.1016/j.ophtha.2009.06.003. Epub 2009 Sep 18.

PMID: 19766317 [PubMed indexed for MEDLINE] Free PMC Article

Macular structure and vision of patients with macular heterotopia secondary to retinopathy of

prematurity.

Soong GP, Shapiro M, Seiple W, Szlyk JP.

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PubMed optical coherence tomography and rop

Normal Foveal Development

Am J Ophthalmol 2012; 154:767-778


W22-25 thick GCL thin ONL

W28-34 thinned GCL,IPL,INL foveal pit develops


D1-D8 fused inner layers-thinner thick ONL

13M-15M thin IRL thick ONL-multilayer cone cone packing


3,5Y – 13Y no neuron left at pit center thick ONL – cone packing (108400/mm²)

Hand-held non contact OCT

Spectralis FD-OCT Heidelberg Engineering Carlsbad California

SD-OCT unit Bioptigen Inc., Research Triangle Park, NC

Lejla Vajzovic et al.



Maldonado et al.

Macular Findings in ROP adults

Daniel X Hamer et al. Foveal fine structure in ROP: an adaptive opticsFourier domain optical coherence tomography. Invest Ophthalmol Vis Sci 2008 May;49(5):2061-2070

Control group – 121± 4,3µm ROP group – 53± 9,9µm

Foveal Pit Wider and Shallower in ROP subjects

Vessels overlying all ROP subjects Persistence inner retinal layers Inner retinal layers thicker all ROP subjects Normal outer retinal layers

Daniel X Hamer et al.

Anand Vinekar et al.

OCT Macular Findings in acute ROP Phases

54 premature infants with ROP 20 premature infants without ROP

79 eyes ROP stage 2 – 23 (29%) CME Eyes with no ROP or Stage 1 – No CME

Anand Vinekar et al.

All subclinical findings Resolve by 52 W PMA

Biochemical Theory Traccional Theory

Longtime effects in Visual Function

Annie C Lee et al

61% CME

Annie C Lee et al.Macular features from spectral domain OCT as an adjunct to indirect ophthalmoscopy in ROP. Retina 2011 September; 31(8):1470-1482

Not visualised by indirect ophthalmoscopy

Annie C Lee et al.Macular features from spectral domain OCT as an adjunct to indirect ophthalmoscopy in ROP. Retina 2011 September; 31(8):1470-1482

Not visualised by indirect ophthalmoscopy

Before iv Ranibizumab and 2 months later

Muhammet Kazim Herol and col.

Before iv Ranibizumab and 2 weeks later

Before ranibizumab injection and after

(a)

(b)

Choroidal thickness

Kyung-Ah, Sei Yeul Oh. Analysis of spectral-domain optical coherence tomography in preterm children: Retinal layer thickness and choroidal thickness profiles. Invest Ophthalmol Vis Sci. 2012;53:7201-7207

5Y – 25w

6Y – 30w

6Y – Full term

Choroidal thickness

OCT findings in normal full term infants

M T Cabrera and col. Sub foveal fluid in healthy full-term newborns observed by Handheld spectral-domain optical coherent tomography. Am J Ophthalmol 2012;153:167-175

Michelle T Cabrera

OCT Periferal Retinal Findings in acute ROP Phases Sai H Chavala et al.Insights into advance ROP using Handheld Spectral Domain OCT

imaging. Ophthalmology 2009 December; 116(12):2448-2456

Three very low-birthweight premature infants

Sai H Chavala et al.Insights into advance ROP using Handheld Spectral Domain OCT imaging. Ophthalmology 2009 December; 116(12):2448-2456

A Vinekar etal. A novel technic using spectral domain OCT (spectralis SD-OCT HRA) to image supine non-anaesthetized infants: utility demonstrated in AP-ROP. Eye (2010)24;379-382

A Vinekar et al

A Vinekar et al. A novel technic using spectral domain OCT (spectralis SD-OCT HRA) to image supine non-anaesthetized infants: utility demonstrated in AP-ROP. Eye (2010)24;379-382

Rajev H Muni et al. Retinoschisis detected with handheld Spectral-domain OCT in neonates with advanced ROP. Arch Opthalmol. 2010;128(1):57-62

(a)

(b)

3D Reconstruction

R Maldonado and col. Optical coherence tomography in retinopaty of prematurity Looking beyond the vessels. Clin Perinatol. 2013 June;40(2):271-296

(a)

(b)

R Maldonado and col. Optical coherence tomography in retinopaty of prematurity Looking beyond the vessels. Clin Perinatol. 2013 June;40(2):271-296

Thin hiperreflective layer separated from retina

2 laser treatments, 1 iv bevacizumab LE

BS 25W -610gr

OCT

Need to evaluate clinical significance and predictive value of novel SDOCT findings in premature infants

Useful adjunct to ROP screening and treatment

Sub clinical information

Great amount of new information

oct in retinopathy of prematurity - livemedia.gr · b a r te s e lli g , d e ll'a r ti l , p...

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