nucleotide-based therapeutic agents

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Nucleotide-based therapeutic agents. MAJOR DRAWBACKS OF ANTISENSE OLIGONUCLEOTIDES. Biologic instability. MAJOR DRAWBACKS OF ANTISENSE OLIGONUCLEOTIDES. Biologic instability Cellular targeting Uptake Efflux from endosomes. MAJOR DRAWBACKS OF ANTISENSE OLIGONUCLEOTIDES. - PowerPoint PPT Presentation

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Page 1: Nucleotide-based   therapeutic agents
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MAJOR DRAWBACKS OFANTISENSE OLIGONUCLEOTIDES

Biologic instability

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MAJOR DRAWBACKS OFANTISENSE OLIGONUCLEOTIDES

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MAJOR DRAWBACKS OFANTISENSE OLIGONUCLEOTIDES

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INIBIT GENE EXPRESSION

INIBIT PROTEIN FUNCTION

AS-ODN siRNA mAbs Small molecule inhibitors