nucleophilic amination of 2-iodo-3-nitro-1-(phenylsulfonyl)indole

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2007 Indole derivatives R 0140 Nucleophilic Amination of 2-Iodo-3-nitro-1-(phenylsulfonyl)indole. — The readily available 2-iodo-3-nitroindole (I) undergoes S N Ar reaction with amines under simple reaction conditions to give pharmacologically interesting derivatives. — (ROY, S.; GRIBBLE*, G. W.; Tetrahedron Lett. 48 (2007) 6, 1003-1005; Dep. Chem., Dartmouth Coll., Hanover, NH 03755, USA; Eng.) — Mais 20- 106

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Page 1: Nucleophilic Amination of 2-Iodo-3-nitro-1-(phenylsulfonyl)indole

2007

Indole derivativesR 0140 Nucleophilic Amination of 2-Iodo-3-nitro-1-(phenylsulfonyl)indole. — The readily

available 2-iodo-3-nitroindole (I) undergoes SNAr reaction with amines under simple reaction conditions to give pharmacologically interesting derivatives. — (ROY, S.; GRIBBLE*, G. W.; Tetrahedron Lett. 48 (2007) 6, 1003-1005; Dep. Chem., Dartmouth Coll., Hanover, NH 03755, USA; Eng.) — Mais

20- 106