nuclear medicine physics

Nuclear Medicine Physics

Fleming JS

Comparison of geometric mean with posterior view renography in the assessment of renal function

Nucl ear Medicine Communications, 27, 2006, 305

Tossici-Bolt L, Hoffmann SM, Kemp PM, Metha RL, Fleming JS

Quantification of [(123)I]FP-CIT SPECT brain images: an accurate technique for measuring the specific binding ratio

Eur J Nucl Med Mol Imaging, in press, 2006,

Fleming JS, Quint M, Bolt L, Martonen TB Conway JH

Comparison of SPECT aerosol deposition data with twenty-four hour clearance measurements.

Journal of Aerosol Medicine ., 2006, In press

Bolt L Fleming JS, Conway JH Martonen TB

An analytical technique to recover the third dimension in planar imaging of inhaled aerosols : (1) Impact on spatial quantification

Journal of Aerosol Medicine, 2006, In press

Bolt L, Fleming JS, Kemp PM

The 3D fractal dimension of DaTSCAN images

Nuclear Medicine Communications, 27, 2006, 296

Fleming JS Zivanovic MA, Blake GM, Burniston M Cosgriff PS

Controversies in the estimation of glomerular filtration rate

Nuclear Medicine Communications, 27, 2006, 407-408

Fleming JS, Pitcairn G, Newman S

Defining the lung outline from a gamma camera transmission attenuation map

Physics in Medicine and Biology, 51, 2006, 1791-1805

Fleming JS

A Technique for analysis of geometric mean renography


Dawson AH, Fleming JS, Hoffmann SMA, Papaspurou L, Peel S

Computer simulation of gamma camera images of the kidney


Fleming, J.S. Zivanovic M.A., Blake, G.M., Burniston M, Cosgriff P.S., Nunan, T.O.

Guidelines for the measurement of glomerular filtration rate using plasma sampling


Fleming JS, Bolt, L. Conway, J.H., Quint M., Martonen, T.B

Comparison of intra-pulmonary aerosol deposition by 3D imaging and 24 hour clearance

Journal of Aerosol Medicine, 18, 2005, 104

Kemp, PM, Hoffmann SA, Holmes C, Bolt L., Ward T, Holmes RB, Felming, J.S.

The contribution of statistical parametric mapping in the assessment of precuneal and medial temporal lobe perfusion by Tc-99m-HMPAO SPECT in mild Alzheimer’s and Lewy body dementia


Hofmann W, Sturm R, Fleming JS, Conway JH, Bolt L.

Simulation of three-dimensional particle deposition patterns in human lungs and comparison with experimental SPECT data.

Journal of Aerosol Science and Technology, 39, 2005, 771-781

Wilby SL, Fleming JS, Hoffmann SMA, Heinle F, Heinle I, Reid C, Misson S.

Enhancing the display of pulmonary embolism (PE) using planar scintigaphy

European Journal of Nuclear Medicine and Molecular Imaging, 32 Supplement 1, 2005, S212-S213

Skrypniuk JV, Bailey D, Cosgriff, PS, Fleming JS, Houston AS, Jarritt PH, Whalley DR

UK audit of left ventricular ejection fraction estimation from equilibrium ECG gated blood pool images


Kemp PM, Hoffmann SMA, Holmes C, Ward T, Bolt L, Fleming JS

The role of HMPAO imaging of the precuneus and medial temporal lobe in suspected Alzheimer’s disease.


Fleming JS, Persaud L, Zivanovic MA.

A general equation for estimating glomerular filtration rate from a single plasma sample


Ward T, Fleming JS, Hoffmann SM, Kemp PM

Simulation of realistic abnormal SPECT brain perfusion images: application in semi-quantitative analysis


Fleming JS, Bolt L, Conway JH, Quint M, Martonen TB.

Comparison of intra-pulmonary aerosol deposition distribution by 3D imaging and 24 hour clearance


Ward T, Hoffmann SMA, Fleming JS, Kemp PM

Comparison of SPM and BRASS using clinically realistic simulated abnormal images

European Journal of Nuclear Medicine and Molecular Imaging, 32 Supplement 1, 2005, S123

Bolt L, Gwynne G, McNeice A, Ward T, Kemp PM, Fleming JS

Quantification of DaTSCAN images: relevance of scatter and septal penetration correction


Fleming JS, Persaud L, Zivanovic MA

Quality control of slope-intercept measurements of glomerular filtration rate using single-sample estimates


Bolt L, Gwynne G, McNeice A, Ward T, Kemp PM, Fleming JS

Quantification of DaTSCAN images: relevance of scatter and septal penetration correction



Enhancing the display of pulmonary embolism using planar scintigraphy.


Nijran KS, Fleming JS, Skrypniuk JV, Whalley DH, Jarritt PH, Houston AS

UK audit of quatitative parameters obtained from a physical phanton generated renography.


Kemp PM, Hoffmann SMA, Holmes C, Ward T, Bolt L, Fleming JS

The role of HMPAO imaging of the precuneus and medial temporal lobe in suspected Alzheimer’s disease.



Enhancing the display of pulmonary embolism using planar scintigraphy


Peel S, Fleming JS, Hoffmann SMA, Papaspyrou L

The simulation and improvement of planar radionuclide images of the kidney


Nijran KS, Fleming JS, Skrypniuk JV, Whalley DH, Jarritt PH, Houston AS

UK audit of quantitative parameters obtained from a physical phantom generated renography


Peel S, Fleming JS, Hoffmann SMA, Papaspyrou L

The simulation and improvement of planar radionuclide images of the kidney.


Ward, T., Fleming, J.S., Hoffmann, S.M.A. Kemp, P.M.

A simulation method for realistic abnormal SPECT brain perfusion images.


Tristam M., Abercrombie C.L., Orchard, K.H., Zivanovic M.A., Johns S.L., Causer, L., Westmore, M.J., Cooper, M., Quadri, S., Lewington, V.J., Fleming, J.S.

Dosimetry for Marrow-Targeted Radioimmunotherapy

European Journal of Nuclear Medicine, 31 (suppl 2), 2004, S473

Ward T. Fleming, J.S, Hoffmann, S.M.A., Kemp, P.M.

Simulation of realistic abnormal SPECT brain perfusion images: methods and applications .

Rueckert D, Hajnal, J, Yang, G-Z, Proceedings of Medical Image Understanding and Analysis 2004, Imperial College, London, 2004, 113-116

Hoffmann S.A., Houston, A.S., Sanders, L., Kemp, P.M.

Reproducibility of HMPAO brain imaging between two hospitals using images obtained from the same patients

Journal of Nuclear Medicine, 45 5 (suppl), 2004, 391P

Fleming JS, Whalley, DR Skrypniuk JV, Jarritt PH, Houston AS, Cosgriff PS, Bailey D

UK audit of relative lung function measurement from planar radionuclide imaging


Hoffmann, S.M.A., Fleming, J.S., Ward, T.

Updating to SPM2 from SPM99 for HMPAO SPECT brain image analysis


Sbirlea-Apiou G., Lemaire, M., Katz, I., Conway. J. Fleming J, Matronen T.

Simulation of the regional manifestation of asthma

Journal of Pharmaceutical Sciences, 93, 2004, 1205-1216

Bolt, L., Fleming, J.S., Kemp, P.M.

The fractal dimension of DaTSCAN images. Is it a clinically useful index?


Fleming, J.S., Zivanovic, M.A., Blake, G.M. Burniston, M., Cosgriff, P.S.

Guidelines for the measurement of glomerular filtration rate using plasma sampling


Fleming, J.S. Nunan, T.O.

The new BNMS guidelines for measurement of glomerular filtration rate


Stratford, J.S. Fleming, J.S.

A comparison of sequential and simultaneous subtraction imaging of the parathyroid. 25


Fleming J.S., Sauret, V, Conway, J.H., Martonen, T.B.

Validation of the conceptual anatomical model of the lung airway.

Journal of Aerosol Medicine, 17, 2004, 260-269

Fleming JS, Bolt L. Stratford JS, Kemp PM.

The specific uptake size index for quantifying radiopharmaceutical uptake

Physics in Medicine and Biology, 49, 2004, N227-N234

Fleming, J.S.

Measuring drug deposition by airway generation in humans

Dalby, R.N. Byron P.R, Peart J, Suman,J.D., Farr, S.J., Respiratory Drug Delivery IX, River Grove Illinois, Davis Healthcare International Publishing, LLC, 2004, 187-193

Fleming J.S.

Design and performance of different gamma camera systems for PET

Hillel P, Basics of Gamma Camera Positron Emission Tomogrpahy, York, Institute of Physics and Engineering in Medicine, 2004, 16-33

Williams J., Kemp, P.M., Hoffmann, S.M.A., Langford, J., Huggett, S.M.

Evaluation of a motion correction algorithm for brain imaging using clinical data


Pitcairn, G., Kalirai, C., Joyson, A., Newman, S., Fleming J.

Development of a standard method for quantifying regional lung deposition from SPECT and relating the data to airway anatomy.

Dalby, R.N. Byron P.R, Peart J, Suman,J.D., Farr, S.J., Respiratory Drug Delivery IX, River Grove Illinois, Davis Healthcare International Publishing, LLC, 2004, 621-624

Cosgriff PS, Fleming JS, Jarritt PH, Skrypniuk J, Bailey D, Whalley D, Houston AS, Blake GM, Burniston M

UK audit of GFR measurement - an update

Nuclear Medicine Communications, 24, 2003, 467 (Abstract)

Bolt L, Fleming JS, Hoffmann SMW, Kemp PM, Costa DC

Quantifying DaTSCAN images: how automation reduces operator variability

Nuclear Medicine Communications, 24, 2003, 445 (abstract)

Kemp, P. M., Holmes, C., Hoffmann, S.M.A., Bolt, L. Fleming, J.S., Ward, A., Thom, J., Zivanovic, M.A., Wilkinson, D.

A randomised double-blind placebo-controlled study to assess the efects of cholinergic theray in Alzheimer’s disease as demonstrated by imaging the post-synaptic muscarinic receptor.

European Journal of Nuclear Medicine, 30, 2003, S223

Kemp, P.M., Hoffmann, S.M.A., Bolt, L. Holmes, R.B. Fleming, J.S.

HMPAO SPECT scan differences in early and late onset Alzheimer’s disease as assessed by statistical parametric mapping Nuclear Medicine Communications, 24, 2003, 444

Misson, S.C., Fleming, J.S., Hoffmann, S.M.A., Nagaraj, N.

Simultaneous ventilation perfusion imaging


Langford, J., Kemp, P.M., Bolt, L., Hoffmann, S.M.A., Fleming, J.S.

DaTSCAN : can a planar vertex view be of any use?


Holmes, R.B. Kemp, P.M., Hoffmann, S.M.A., Fleming J.S., Bolt, L., Ward, A.

Is age correction necessary for an HMPAO rCBF normal database?


Fleming, J.S., Whalley, D.R., Skrypniuk, J.V., Jarritt, P.H., Houston, A.S., Cosgriff, P.S., Bailey, D.

UK audit of relative lung function measurement from planar radionuclide imaging


Ward, T., Hoffmann, S.M.A., Kemp, P.M., Holmes, R.B., Fleming, J.S., Bolt, L.

The importance of age adjustment in an SPM HMPAO rCBF normal database.


Houston, A.S., Hoffmann, S.M.A., Sanders, L., White, D.R.R., Bolt, L., Fleming, J.S., Macleod, M.A., Kemp, P.M.

Combining rCBF images obtained from different centres in a composite normal atlas.

Barber D, Proceedings of Medical Image Understanding and Analysis 2003, Sheffield, University of Sheffield, 2003, 13-16

Reid, C.J., Misson, S, Fleming, J.S., Sawyer, L, Hoffmann, S.A. Nagaraj, N.

Enhanced display of pulmonary embolism in simultaneous dual isotope ventilation/perfusion planar scintigraphy.

Barber, D, Proceedings of Medical Image Understanding and Analysis 2003, Sheffield, University of Sheffield, 2003, 173-176

Martonen, T.B., Fleming, J.S., Schroeter, J. Conway, J.H. Hwang, D.

In-silico modelling in asthma.

Advanced Drug Delivery Reviews, 55, 2003, 829-849

Kemp, P.M., Holmes, C., Hoffmann, S.M.A., Bolt, L., Holmes, R., Rowden, J, Fleming, J.S.

Alzheimer’s disease: differences in Tc-99m HMPAO SPECT scan finsdings between early and late onset dementia.

Journal of Neurology, Neurosurgery and Psychiatry, 74, 2003, 715-719

Fleming JS, Conway JH, Bolt L, Holgate ST

A comparison of planar scintigraphy and SPECT measurement of total lung deposition of inhaled aerosol

Journal of aerosol medicine, 16, 2003, 9-16

Tristam, M., Orchard, K.H., Zivanovic, M.A., Johns, S.L., Causer, L, Cooper, M., Quadri, S, Lewington, V.J., Fleming, J.S.

Dosimetry for radioimmunotherapy.


Feming JS

The detection of radiation in sample counters

Driver I, Radioactive Sample Counting:Principles and Practice, York, IPEM, 2002, 1-14

Bolt, L., Fleming, J.S., Kemp, P.M.

Quantifying DaTSCAN images: is the technique robust and useful?


Schroeter JD, Fleming, JS, Hwang, D, Martonen, TB

A computer model of lung morphology to analyze SPECT images.

Computerized Medical Imaging and Graphics, 26, 2002, 237-246

Sauret V., Halson, P.H., Brown, I.W., Fleming. J.S., Bailey, A.G.

Study of the three-dimensional geometry of the central conducting airways in man using computed tomographic (CT) images.

Journal of Anatomy, 200, 2002, 123-134

Jarritt, P.H., Whalley, J.V., Skrypniuk, J.V., Houston, A.S., Fleming, J.S. Cosgriff, P.S.

UK audit of single photon emission computed tomography reconstrcution software using software generated phantoms.


Martonen, T.B., Schroeter, J.D., Zhang, Z., Hwang, D., Fleming, J.S.

Targeted delivery of inhaled proteins.

In Dalby, R.N., Byron, P.R., Peart, J., Farr, S.J., Respiratory Drug Delivery VIII Program and Proceedings Volume II, Godalming, Surrey, Davis Horwood International, 2002, 723-725

Fleming J.S., Kemp, P.M., Bolt, L., Goatman, K.A.

Measurement of cerebral perfusion volume and Tc-99m HMPAO uptake using SPECT in controls and patients with Alzheimer’s disease.


Bolt l, Fleming JS, Kemp PM

Quantifying DaTSCAN images: is the technique robust an duseful?


Fleming, J.S., Persaud, L, Ralls, K, Burry, S, Fleming, P.J., Zivanovic, M.

Quality control of two-sample GFR measurements using single-sample estimates.


Cosgriff, P.S., Fleming, J.S., Jarritt, P.H., Skrypniuk, J., Bailey, D., Whalley, D, Houston. A., Burniston, M.

UK audit of GFR measurements.


Cosgriff PS, Fleming JS, Jarritt PH, Skrypniuk J, Bailey D, Whalley D, Houston A, Burniston M

UK audit of GFR measurements


Hoffmann, S.M.A., Bolt, l., Fleming, J.S., Kemp, P.M.

Optimising parameters in statistical parametric mapping for HMPAO SPECT images.


Heikkinen, J.O., Houston, A.S., Fleming, J.S.

Physical phantom for renography: English survey.


Morris SL, Fleming JS, Kemp P,

A Comparison of OSEM and the FBP Algorithms in Cerebral Perfusion Imaging


Nagaraj, N, Langford, J., Fleming, J.S., Kemp, P.M., Hall, M.

Evaluation of NORA (normalised residual activity) in antenatal unilateral hydronephrosis.


Fleming, J.S.

Computer methods for the assessment of the fate of inhaled aerosol using data from multimodality imaging.

Martonen, T.B., Medical Applications of Computer Modelling, Volume 2 : The Respiratory System., Southampton, WIT Press, 2001, 305-332

Fleming, J.S., Conway, J.H.

Three-dimensional imaging of aerosol distribution.

Journal of Aerosol Medicine,, 14, 2001, 147-153

Walker, P, Conway, J.H., Fleming, J.S., Bondesson, E, Borgstrom, L.

Pulmonary clearance rate of two chemically different forms of inhaled pertechnetate.


Fleming, J.S., Conway, J.H., Bolt, L., Epps, B., Bailey, A.G., Holgate, S.T., Martonen, T.B.

Comparison of SPECT data on regional aerosol deposition with empirical modelling.


Houston, A.S. Whalley, D.R., Skrypnuik, J.V., Jarritt, P.H., Fleming, J.S., Cosgriff, P.S.

UK audit and analysis of quantitative parameters obtained from gamma camera renography


Kemp, P.M., Bolt, L., Goatman, K.A. Fleming, J.S.

HMPAO SPECT in pre-senile Alzheimer’s dementia: parietal hypoperfusion precedes medial temporal abnormalities. .


Schroeter, J.D., Fleming, J.S., Hwang, D., Martonen, T.B.

Development of 3-D computer lung models to analyse SPECT images.


Skrypnuik, J.V., Bailey, D., Cosgriff, P.S. Fleming, J.S., Houston, A.S. Jarritt, P.H., Whalley, D.R.

Results of the IPEM/BNMS MUGA audit.


Jarritt, P.H., Whalley, D.R., Cosgriff, P.S., Fleming, J.S., Houston, A.S., Skrypniuk, J.V.

IPEM/BNMS UK audit of quantitative parameters obtained from nuclear medicine SPET software.

European Journal of Nuclear Medicine, 27, 2000, 942

Martonen, T.B., Musante, C.J., Segal, R.A., Schroeter, J.D., Hwang, D., Dolovich, M.A., Burton, R., Spencer, R.M. Fleming, J.S.

Lung models: strengths and limitations.

Respiratory Care, 45, 2000, 712-736

Kemp, P.M., Bolt, L., Fleming, J.S., Goatman, K.A.

Tc99m HMPAO SPET cerebral perfusion imaging in dementia : is it necessary to normalise the images?


Houston, A.S., Whalley, D.R., Skrypniuk, J.V., Jarritt, P.H., Fleming, J.S., Cosgriff, P.S.

UK audit of quantitative nuclear medicine renography.

European Journal of Nuclear Medicine., 27, 2000, 990

Sauret, V, Fleming, J.S., Bailey, A.G.

The use of multimodality imaging to study the pulmonary deposition of inhaled aerosol.

Allen, R., Fleming, J.S., and Petley, G.W, Proceedings of the Sixth Annual National Conference of the Institute of Physics and Engineering in Medicine, York, IPEM, 2000, 56

Sauret, V., Fleming, J.S., Bailey, A.G.

3D computer asymmetric model of the airways.



Factors affecting quantitative parameters obtained from renography.


Goatman, K.A., Fleming, J.S., Bolt, L. Kemp, P.M..

An automatic method for measuring functional brain volume using SPECT imaging.

Proceedings of Medical Image Understanding and Analysis MIUA2000, London, Communications in Print plc, 2000, 157-160

Walker, P.S., Pettersson, Conway, J.H., Fleming, J.S., Bondesson, E., Borgstrom, L.

Pre-clinical validation of a terbutaline sulphate labelling procedure.

Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J, Respiratory Drug Delivery VII Program and Proceedings Volume II, Raleigh, NC, Serentec Press, 2000, 531-534

Fleming, J.S., Kemp, P.M., Bolt, L., Goatman, K.A.

Functional brain volume from HMPAO SPET: reproducibility and application in Alzheimer’s disease.


Sauret, V, Fleming, J.S., Bailey, A.G.

3D realistic anatomical model of the central airways to improve aerosol deposition predictions and medical image analysis. Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J.I, Respiratory Drug Delivery VII Program and Proceedings Volume I, Raleigh, NC, Serentec Press, 2000, 527-530

Jarritt, P.H., Whalley, D.R., Cosgriff, P.S., Fleming, J.S., Houston, A.S., Skrypniuk, J.V.

IPEM/BNMS UK audit of quantitative parameters obtained from nuclear medicine SPET software.


Bolt, L, Fleming, J.S., Goatman, K.A

Influence of acquisition and processing factors on image quality in gamma camera PET.


Fleming, J.S.,

Deconvolution analysis or renal outflow efficiency?

Journal of Nuclear Medicine,, 41, 2000, 1595-1596

Fleming, J.S., Conway, J.H., Holgate, S.T., Bailey, A.G., Martonen, T.B.

Comparison of methods for deriving aerosol deposition by airway generation from three-dimensional radionuclide imaging

Journal of Aerosol Science, 31, 2000, 1251-1259

Fleming, J.S., Goatman, K.A., Julyan, P.J., Boivin, C.M., Wilson, M.J., Barber, R.W., Bird, N.J. Fryer, T.D

A comparison of performance of three gamma camera systems for positron emission tomography.


Fleming, J.S., Conway, J.H., Walker, P.S., Bondesson, E., Borgstorm, L., Martonen, T.B., Holgate, S.T.

The influence of pulmonary clearance on quantitative three dimensional radionuclide imaging of inhaled aerosol deposition. Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J., Respiratory Drug Delivery VII Program and Proceedings Volume II, Raleigh, NC, Serentec Press, 2000, 523-526

Conway, J.H., Walker, P.S., Fleming, J.S., Bondesson, E., Borgstrom, L. Holgate, S.T.

Three-dimensional description of the deposition of inhaled terbutaline sulphate administered via Turbuhaler.

Dalby, R.N., Byron, P.R., Farr, S.J., Peart, J., Respiratory Drug Delivery VII Program and Proceedings Volume II, Raleigh, NC, Serentec Press, 2000, 607-610

Tristam, M., Fleming, J.S., Lewington, V.J., Zivanovic, M.A., Wilson, L.M.

Advances in targeted radionuclides therapies.

Allen, R., Fleming, J.S., and Petley, G.W, Proceedings of the Sixth Annual National Conference of the Institute of Physics and Engineering in Medicine, York, IPEM, 2000, 57

Fleming, J.S., Sauret, V., Conway, J.H., Holgate, S.T., Bailey, A.G., Martonen, T.B.

Evaluation of the accuracy and precision of lung aerosol deposition measurements from SPECT using simulation.


Sauret, V., Goatman, K.A., Fleming, J.S. Bailey, A.G.

3D topology and morphology of branching networks using computed tomography - applications to the airway tree.

Hawkes D, Hill D, Gaston R, Proceedings of Medical Image Understanding and Analysis 99, London, BMVA, 1999, 73-76

Sauret, V., Fleming, J.S., and Bailey, A.G.

Three dimensional topology and morphology of airways using lung cast CT images.


UK audit and analysis of quantitative parameters obtained from nuclear medicine renography.

Image Processing: Implementation of Research into Clinical Application: Virtual Meeting., IPEM web site (www.ipem.org.uk), 1999,

Fleming, J.S., Kemp, P.M., and Bolt, L.B.

A technique for manual definition of an irregular volume of interest in single photon emission computed tomography.

Physics in Medicine and Biology, 44, 1999, N15-N20

Martonen, T.B., Zhang, Z., Yu, G., Musante, C., Hwang, D., Segal, R., and Fleming, J.S

Targeted delivery of inhaled proteins.


Fleming, J.S., Kemp, P.M.

A comparison of deconvolution and the Patlak-Rutland plot in renography analysis.


Fleming, J.S.

Accuracy of estimation of glomerular filtration rate from renography.

Journal of Nuclear Medicine, 40, 1999, 1968-1969

Sauret, V., Goatman, K.A., Fleming, J.S. and Bailey, A.G.

Semi-automated tabulation of the 3D topology and morphology of branching networks using CT: application to the airway tree. Physics in Medicine and Biology.


Fleming, J.S., and Kemp, P.M.

A comparison of deconvolution and the Patlak-Rutland plot in renography analysis.


Houston, A.S., Whalley, D.R., Skrypniuk, J.V., Jarritt, P.H. Fleming, J.S., Cosgriff, P.S.

UK audit of quantitative parameters obtained from nuclear medicine renography.


Goatman, K.A., Fleming, J.S.

Attenuation correction for gamma camera PET systems using a moving 99Tcm line source.


Fleming, J.S., Sauret, V., Conway, J.H., Holgate, S.T., Bailey, A.G. and Martonen, T.B.

A technique for deriving airway deposition data from 3D radionuclide imaging of inhaled aerosol (SPECT).


Kemp, P.M. Bolt, L.B., Goatman, K.A., Martin, D.S. Williams, J. Fleming, J.S.

99Tcm-HMPAO rCBF findings in healthy male volunteers: Can they be distinguished from early Alzheimer’s dementia?


Fleming, J.S., Kemp, P.M., Bolt, L.B., Goatman, K.A.

Functional brain volume and 99mTc HMPAO uptake on SPET in control subjects and patients with mild to moderate Alzheimer’s disease.


Conway, J.H., Walker, P., Perkins, G, Fleming, J.S., Holgate, S.T.

Lung deposition characteristics of HFA-134a beclamethasone diproprionate delivered via an Autohaler. 1999, 196

European Respiratory Journal,, 1999, 196

Fleming, J.S., Goatman, K.A., Julyan, P.J., Boivin, C.M., Wilson, M.J., Barber, R.W., Bird N.J., Fryer, T.D

A comparison of the performance of three gamma camera systems for PET.


Fleming, J.S., Cosgriff, P.C., Houston, A.S., Jarritt, P., Skrypniuk, J, Whalley, D.

An audit of quatitative relative renal function assessment from static scintigraphy in the United Kingdom.

Journal of Nuclear Medicine, 39(5 supplement), 1998, 17P

Fleming, J.S, Cosgriff, P.S., Houston, A.S., Jarritt, P.H., Skrypniuk, J.V., Whalley, D.R.,

United Kingdom audit of relative renal function measurement using DMSA scintigraphy.


Martonen, T.B., Hwang, D., Guan, X, Fleming, J.S.

Supercomputer description of human lung morphology for imaging analysis.


Fleming, J.S., Conway, J.H., Holgate, S.T., Moore, E.A., Hashish, A.H., Bailey, A.G., Martonen, T.B.,

Evaluation of the accuracy and precision of lung aerosol deposition measurements from planar imaging using simulation., Physics in Medicine and Biology, 43, 1998, 2423-2429

Fleming, J.S., Alaamer, A.S.

A rule based method for context sensitive threshold segmentation in SPECT using simulation.


Hashish, A.H., Fleming, J.S., Conway, J.H., Halson, P, Moore, E.A. Williams, T.J., Bailey, A.G., Nassim, M.A., Holgate, S.T.,

Lung deposition of particles by airway generation in healthy subjects: three dimensional radionuclide imaging and numerical model prediction.

Journal of Aerosol Science, 29, 1998, 205-215

Fleming, J.S., Conway, J.H., Holgate, S.T., Moore, E.A., Bailey, A.G., Martonen, T.B.

The use of simulation in evaluating the accuracy and precision of lung aerosol deposition measurements from planar imaging.

Journal of Nuclear Medicine, 39(5 supplement),, 1998, 98P

Fleming, J.S., Cosgriff, P.C., Houston, A.S., Jarritt, P., Skrypniuk, J, Whalley, D.

U.K. audit of relative renal function assessment by DMSA scintigraphy.


Fleming, J.S., Conway, J.H., Holgate, S.T., Moore, E.A., Bailey, A.G., Martonen, T.B.

Evaluation of the accuracy and precision of pulmonary aerosol deposition measurements from planar imaging using simulation.


McGrath, D.M., Daniell, G.J., Fleming, J.S.

Maximum entropy deconvolution of low count nuclear medicine images.

IPA97 IEE Conference publication No. 443, 1997, 274-278

Fleming, J.S., Waller, D.W.

Feasibility of estimating glomerular filtration rate in children using the single sample adult technique.


Hofmann, W., Koblinger, L., Bergmann, R., Fleming, J.S., Hashish, A.H., Conway, J.H

Spatial aerosol deposition patterns in the human lung: stochastic predictions versus experimental SPECT data.

Annals of Occupational Hygiene, 41(Supplement 1), 1997, 576-581

Fleming, J.S., Hashish, A.H., Conway, J.H., Hartley-Davies R, Nassim, M.A., Guy, M.J., Coupe, J, Holgate, S.T., Moore, E.A., Bailey, A.G., Martonen, T.B.

A technique for simulating radionuclide images from the aerosol deposition pattern in the airway tree.


Conway, J.H., Fleming, J.S., Holgate, S.T.

Three dimensional imaging of inhaled aerosols.

European Respiratory Review, 7, 1997, 180-183

McGrath, D.M., Daniell, G.J., Fleming, J.S.

Maximum entropy deconvolution of low count nuclear medicine images. In eds ,

Taylor C.J., Noble J.A, Brady J.M, Medical Image Understanding and Analysis ‘97, Manchester, U.K., BMVA, 1997, 165-168

Tristam, M, Fleming, J.S., Lewington, V.J. Zivanovic, M.A., Johns, S.L.

Tumour dosimetry in mIBG therapy: a case study.

European Journal of Nuclear Medicine, 24, 1997, 986

Conway, J.H., Moore, E.A., Halson, P,. Hashish, A.H., Bailey, A.G., Fleming, J.S., Holgate, S.T.

How reproducible is SPECT and MRI in the assessment of deposition of nebulised aerosols? American Journal of Respiratory and Critical Care Medicine, 1997

American Journal of Respiratory and Critical Care Medicine, 1997,

Fleming J.S., Hashish, A.H., Conway, J.H., Bailey, A.G., Holgate, S.T., Moore E.A., Martonen, T.B.

The use of simulation in the interpretation of three dimensional multi-modality imaging of aerosol deposition in the lung.

Medical and Biological Engineering and Computing, 35 (Supplement part 2),, 1997, 809


A rule based method for context sensitive threshold segmentation in SPECT using simulation.

Medical and Biological Engineering and Computing, 35 (Supplement part 2), 1997, 802

Fleming, J.S., Hashish, A.H., Conway, J.H., Nassim, M.A., Guy, M.J., Coupe, J, Bailey, A.G., Holgate, S.T., Moore, E.A., Martonen, T.B.

Radionuclide image simulation in the evaluation of accuracy and precision of aerosol deposition measurement in scintigraphy.



Improved accuracy in tumour dosimetry in targeted radiotherapy using a context sensitive threshold techniques for tumour segmentation.


Cosgriff, P, Fleming, J.S., Houston, A, Jarritt, P., Skrypniuk, J, Whalley, D.,

IPEMB Nuclear Medicine Software Working Party.


Aldous, A.J., Zivanovic, M.A., Johns, S., Lewington, V., Vettulatitli, J.J., Fleming, J.S., Salmon, A.P.

An assessment of techniques for quantification of intrapulmonary arteriovenous shunting in children.


Fleming, J.S., Hashish, A.H., Conway, J.H., Bailey, A.G., Holgate, S.T., Moore, E.A., Martonen, T.B.

The use of simulation in improving the interpretation of 3D multimodality imaging of aerosol deposition. In eds , ,

Taylor C.J., Noble J.A, Brady J.M, Medical Image Understanding and Analysis ‘97, Manchester, U.K.,, BMVA,, 1997, 21-24

Tristam, M., Alaamer, A., Fleming, J.S., Lewington, V.J., Zivanovic, M.A.

Dosimetry of I-131 metaiodobenzylguanidine in cancer therapy.


Fleming JS, Epps B, Conway JH, Martonen TB

Comparison of SPECT aerosol deposition data with a human respiratory tract model.

Journal of Aerosol Medicine, 1996, In press

Conway, J.H., Moore, E.A., Halson, P., Hashish, A.H., Bailey, A.G., Fleming, J.S., Holgate, S.T.

The use of combined SPECT and MRI to assess the effect of airway obstruction on aerosol deposition.

American Journal of Respiratory and Critical Care Medicine., 153, 1996, A482

Hashish, A.H., Fleming, J.S., Conway, J.H., Halson, P., Moore, E., Williams, T.J., Bailey, A.G., Nassim, M.A., Holgate, S.T. Comparison of 3D SPECT data with model predictions of aerosol deposition in the lung.


Fleming, J.S., Alaamer, A.S

The influence of collimator characteristics on quantification in single photon emission computed tomography.


Patankar, R., Ozmen, M.M., Aldous, A., Khader, Z., Fleming, J.S., Johnson, C.D.,

Standardisation of a technique for BrIDA cholescintigraphy.


Fleming, J.S.

Evaluation of a technique for simulation of gamma camera images.


Fleming, J.S., Hashish, A.H., Conway, J.H., Nassim, M.A., Holgate, S.T., Halson, P., Moore, E., Bailey, A.G., Martonen, T.B.

Assessment of deposition of inhaled aerosol in the respiratory tract of man using three dimensional multi-modality imaging and mathematical modelling.


Fleming, J.S., Halson, P., Conway, J.H., Moore, E., Nassim, M.A., Hashish, A.H., Bailey, A.G., Holgate, S.T., Martonen, T.B.

Three dimensional description of pulmonary deposition of inhaled aerosol using data from multimodality imaging.


Summers, Q.A., Fleming, J.S., Dai, Y., Perring, S., Honeywell, R., Gough, K.J., Renwick, A.G., Clark, A.R., Nassim, M.A., Holgate, S.T.

The pulmonary deposition of two aerosol preparations of nedocromil sodium delivered by MDI assessed by single photon emission computed tomography.

Journal of Aerosol Medicine, 9(Supplement 1), 1996, S93-S109

Martonen, T.B., Hwang, D, Guan, X., Yang, Y., Fleming, J.S.,

Computational fluid dynamic simulations of the human lung: an overview.

Cerrolaza, M. Jugo, D., Brebbia, C.A., Simulation Modelling in Bioengineering, Southampton, Computational Mechanics Publications, 1996, 69-78

Fleming, J.S.

Quantitative measurements from gamma camera images.

handler S.T. and Thompson W.H, Mathematical Techniques in Nuclear Medicine,, York, York Publishing Services, 1996, 21-46

Martonen, T.B., Yang, Y., Hwang, D., Fleming, J.S.

Computer model of human lung morphology to complement SPECT analyses.

International Journal of Bio-medical Computing, 40, 1995, 5-16

Fleming, J.S.

Using SPECT to improve monitoring of drug delivery

Improving Drug Delivery from Pressurised Inhalers, Management Forum, London, 1995,

Fleming, J.S., Nassim, M.A., Hashish, A.H., Bailey, A.G., Conway, J.H., Holgate, S.T., Halson, P., Moore, E.A., Martonen, T.B.

Description of pulmonary deposition of radiolabeled aerosol by airway generation using a conceptual three dimensional model of lung morphology.


Holdstock, G., Phillips, G., Hames, T.K., Condon, B.R., Fleming, J.S., Smith, C., Ackery, D.M.

Potential of SeHCAT retention as an indicator of terminal ileal involvement in inflammatory bowel disease.

European Journal of Nuclear Medicine, 10, 1995, 528-530

Martonen, T.B., Yang, Y., Hwang, D., Fleming, J.S.

Computer simulations of human lung structures for medical applications.

Computers in Medicine and Biology, 25, 1995, 431-446

Conway, J.H., Halson, P., Moore, E., Hashish, A.H., Nassim, M., Fleming, J.S., Holgate, S.T.

Multi-modality imaging: the use of single photon emission tomography and magnetic resonance imaging to assess regional intra-pulmonary deposition of nebulised aerosols.


Simpson, D.E., Fleming, J.S., Aldous, A.J., Daniell, G.J.

Deconvolution of planar scintigrams by maximum entropy.


Fleming, J.S., Halson, P., Conway, J., Nassim, M., Hashish, A., Bailey, A.G., Holgate, S., Moore, E., Martonen, T.B.

Description of inhaled aerosol deposition in the lung using a hemispherical transform of multi-modality imaging data. In , eds ,

Y. Bizais, C. Barillot, R. Di Paola, Information Processing in Medical Imaging, Dordrecht, Kluwer Academic Publishers, 1995, 393-394

Fleming, J.S., Nassim, M.A., Hashish, A.H., Bailey., A.G., Conway, J., Holgate, S., Halson, P., Moore, E., Martonen, T.B.

Description of pulmonary deposition of radiolabeled aerosol by airway generation using a conceptual three dimensional model of lung morphology


Fleming, J.S.

Measurement of pulmonary distribution of inhaled aerosol using multimodality medical imaging

Deposition and Fate of Drugs Administered to the Lung, Loughborough UK, 1994,

Perring, S., Summers, Q., Fleming, J.S., Nassim, M.A., Holgate, S.T.

A new method of quantification of the pulmonary regional distribution of aerosols using combined CT and SPECT and its application to nedocromil sodium administered by metered dose inhaler.

British Journal of Radiology, 67, 1994, 46-53

Perring, S., Hind, R., Fleming, J.S., Birch, S., Batty, V., Taylor, I.

Dosimetric assessment of radiolabelled lipiodol as a potential therapeutic agent in colorectal liver metastases using combined CT and SPECT.


Alaamer, A.S., Fleming, J.S., Perring, S.

Evaluation of the factors affecting the accuracy and precision of a technique for quantification of volume and activity in SPECT.


Fleming, J.S., Simpson, D.E.

A technique for simulation of the point spread function of a gamma camera.


Martonen, T.B., Yang, Y., Hwang, D., Fleming., J.S.

Mapping the human lung using delaunay tesselation.

Computers in Biomedical Research, 27, 1994, 245-262

Oliver, R.M., Fleming, J.S., Dawkins, K.D., Waller, D.G.

Normal right ventricular systolic and diastolic function assessed by krypton 81m equilibrium ventriculography.

International Journal of Cardiac Imaging, 9, 1993, 257-264

Simpson, D.E., Daniell, G.J., Fleming. J.S.

3D reconstruction from only two projections?

Mohammad-Djafari, A., Demoments, G, Maximum Entropy and Bayesian Methods, Kluwer Academic Publishers, 1993, 423-429

Oliver, R.M., Fleming, J.S., Waller, D.G.

Right ventricular function at rest and during exercise in chronic obstructive pulmonary disease: comparison of two radionuclide techniques.

Chest, 103, 1993, 74-80

Oliver, R.M., Fleming, J.S., Dawkins, K.D., Waller, D.G

Right ventricular function at rest and during submaximal exercise assessed by krypton 81m equilibrium ventriculography in normal subjects.


Alaamer, A.S., Fleming, J.S., Perring, S.

Evaluation of a technique for the quantification of radioactivity and volume of an object in SPECT.


Fleming, J.S., Alaamer, A.S., Perring, S.

A technique for the absolute quantification of I-131 radiopharmaceuticals using SPECT.


Hind, R.E., Loizidou, M., Perring, S., Fleming, J.S., Batty, V., Birch, S., Taylor, I.

Biodistribution of lipiodol following hepatic arterial ligation.

British Journal of Surgery, 79, 1992, 952-954

Hind, R.E., Loizidou, M., Fleming, J.S., Batty, V., Birch, S., Taylor, I.

Biodistribution of lipiodol following hepatic arterial ligation.

European Journal of Surgical Oncology, 18, 1992, 162-167

Fleming, J.S., Oliver, R.M., Waller, D.G.

Dosimetry assessment of krypton-81 peripheral venous infusion studies.


Fleming, J.S.

Estimation of organ input function and plasma clearance from the cardiac curve in dynamic scintigraphy.


Conway, J.H., Fleming, J.S., Perring, S., Holgate, S.T.

Humidification as an adjunct to chest physiotherapy in aiding tracheo-bronchial clearance in patients with bronchiectasis. Respiratory Medicine, 86, 1992, 109-114

Robertson, D.R.C., Renwick, A.G., Macklin, B.S., Waller, D.G., George, C.F., Fleming, J.S.

The influence of levodopa on gastric emptying in healthy elderly volunteers.

European Journal of Clinical Pharmacy, 42, 1992, 409-412

Hilson, A.J.W., Fleming, J.S.

Radionuclide investigation of the liver.

Oxford Textbook of Clinical Hepatology Vol 1, 1991, 343-352

Fleming, J.S., Wilkinson, J., Oliver, R.M., Ackery, D.M., Blake, G.M., Waller, D.G.

Comparison of radionuclide estimation of glomerular filtration rate using technetium 99m DTPA and chromium 51 EDTA.


Fleming, J.S., Britten, A.J., Perring, S., Keen, A.C., Howlett, P.J.

A general software system for the handling of medical images.

Journal of Medical Engineering Technology, 15, 1991, 162-169

Waller, D.G., Juer, L., Fleming, J.S.

Measurement of glomerular function during cisplatin therapy.

British Journal of Clinical Pharmacology, 31, 1991, 271-274

Waller, D.G., Fleming, J.S., Ramsay, B., Gray, J.

The accuracy of creatinine clearance with and without urine collection as a measure of glomerular filtration during cisplatin therapy. l

Postgraduate Medicine Journa, 67, 1991, 42-46

Perring, S., Hunt, T.M., Fleming, J.S., Blaquiere, R.M., Taylor, I.

Automated measurement of tumour extent in patients with colorectal liver metastases from X-ray computed tomography.


Oliver, R.M., Peacock, A.J., Challenor, V.F., Fleming, J.S., Waller, D.G.

The affect of acute hypoxia on right ventricular function in healthy adults.

International Journal of Cardiology, 31, 1991, 235-242

Fine, D., Perring, S., Herbetko, J., Hacking, C.N., Fleming, J.S., Dewbury, K.

Three dimensional ultrasound of the gallbladder and the dilated biliary tree: reconstruction from real time scans.


Perring, S., Hunt, T.M., Fleming, J.S., Blaquiere, R.M., Taylor, I.

Automatic segmentation of computerised axial tomography (CT) images for assessing tumour extent in patients with colorectal liver metastases.

Computers in Diagnostic Radiology. IPSM report 62, 1990, 91-99

Fleming, J.S.

A technique for the use of standard outlines for attenuation correction and quantification in SPECT.


Robertson, D.R.C., Renwick, A.G., Wood, N.D., Cross, N., Macklin, B.S., Fleming, J.S., Waller, D.G., George, C.F.

The influence of levodopa on gastric emptying in man.

British Journal of Clinical Pharmacy, 29, 1990, 47-53

Wilkinson, J., Fleming, J.S., Waller, D.G.

The effect of food and activity on the reproducibility of isotopic GFR estimation.


Oliver, R.M., Gray, J.M., Challoner, V.F., Fleming, J.S., Waller, D.G.

Krypton-81m equilibrium radionuclide ventriculography for the assessment of right heart function.


Summers, Q.A., Hollingsworth, A., Clark, A.R., Fleming, J.S., Holgate, S.T.

The preparation of a radio-labelled aerosol of nedocromil sodium for administration by metered dose inhaler that accurately preserves the particle size distribution of the drug.

Drug Investigation, 2, 1990, 90-98

Britten, A.J., Fleming, J.S., Flowerdew, A.D.S., Hunt, T.M., Taylor, I., Karran, S.J., Ackery, D.M.

A comparison of three indices of relative hepatic perfusion derived from dynamic liver scintigraphy.

Clinical Physics and Physiological Measurements, 11, 1990, 45-51

Richardson RB, Kemshead JT, Davies AG, Staddon GE, Jackson PC, Coakham HB, Lashford LS

Dosimetry of intrathecal iodine (131) monoclonal antibody in cases of neoplastic meningitis.

Eur J Nucl Med, 17, 1990, 42-48

Britten, A.J., Fleming, J.S., Flowerdew, A.D.S., Taylor, I., Karran, S.J., Ackery, D.M.

Regional indices of relative hepatic arterial perfusion from dynamic liver scintigraphy: the variability of indices and the use of parametric imaging.


Oliver, R.M., Peacock, A.J., Fleming, J.S., Waller, D.G.

Renal and pulmonary effects of angiotensin converting enzyme inhibition in chronic hypoxic pulmonary disease.

Thorax, 44, 1990, 513-515

Hunt,T.M., Flowerdew, A.D.S., Britten, A.J., Fleming, J.S., Karran, S.J., Taylor, I.

An association between parameters of liver blood flow and percentage hepatic replacement with tumour.

British Journal of Cancer, 59, 1989, 410-414

Jackson PC

Developments in radionuclide imaging.

J Photographic Science, 37, 1989, 69-72

Fleming, J.S.

A technique for using CT images in attenuation correction and quantification in SPECT.


Britten,, A.J., Flowerdew, A.D.S., Hunt, T.M., Taylor, I., Ackery, D.M., Fleming, J.S.

A gamma camera method to monitor the use of degradable starch microspheres in hepatic arterial chemotherapy.


Lovick, A.H.J., Richards, H.K., Perry, S., Lees, P.D., Wildern, J., Zivanovic, M., Fleming, J.S., Ackery, D.M., Pickard, J.D.

A comparison of Tc-99m HMPAO uptake with cerebral blood flow measured using freely diffusible tracers in both man and animals.

Blood Flow in the Brain, Oxford, Clarendon Press, 1989, 38-43

Fleming, J.S.

Functional radionuclide imaging of renal mean transit time and glomerular filtration rate.


Murphy, P., Alexander, P., Senior, P.V., Fleming, J.S., Kirkham, N., Taylor, I.

Mechanisms of organ selective tumour growth by blood-borne cancer cells.


Blake, G.M., Lewington, V.J., Fleming, J.S., Zivanovic, M.A., Ackery, D.M.

Modification by nifedipine of I-131 mIBG kinetics in malignant phaeochromocytoma.


Fleming, J.S., Waller, D.G., Blake, G.M., Ackery, D.M.

Measurement of glomerular filtration rate with Tc-99m DTPA : comparison of plasma clearance techniques. Reply to letter. Journal of Nuclear Medicine, 29, 1988, 1153-1154

Jackson PC

The equipment involved in radionuclide imaging

Thomas WEG and Davies ER, Nuclear Medicine: Applications to Surgery, Tunbridge Wells, Kent, Castle House Publications, 1988, 17-37

Richardson RB, Davies AG, Staddon GE, Moseley RP, Kemshead JT, Jackson PC, Coakham HB

Dosimetry of limbar and intraventricular cerebrospinal fluid administration of iodine-131 monoclonal antibodies.

Abst Brit J Radiol, 60, 1987, 628

Britten, A.J., Keen, A.C., Fleming, J.S., Howlett, P.J.

Practical experience of image transfer form nuclear medicine, x-ray CT and video sources to a VAX computer

Tofts, P.S., Cranage, R.W, Networks and Image Handling: Institute of Physical Sciences in Medicine Report 52, York, Institute of Physical Sciences in Medicine, 1987, 63-69

Pitcher EM, Jackson PC, Key H, Stevens PH

Technical factors involved in the superimposition of digital images

Tofts PS & Cranage RA, Networks & Image Handling, York, Institute of Physical Sciences in Medicine, 1987, 70-76

Jackson PC

A glimpse at the ACR-NEMA digital imaging and communications standard

Tofts PS & Cranage RA, Networks & Image Handling, York, Institute of Physical Sciences in Medicine, 1987, 35-43

Waller, D.G., Ramsay, B., Fleming, J.S., Ackery, D.M.

Longitudinal assessment of glomerular filtration rate by gamma camera and portable external detector.


McLaren, M.I., Braye, S., Fleming, J.S., Karran, S.J., Taylor, I.

The changes in blood flow, portal pressure and intra-hepatic shunting during the development of cirrhosis and response to beta-blockade.

Gut, 28, 1987, 663-667

Britten, A.J., Flowerdew, A.D.S., Taylor, I., Fleming, J.S., Ackery, D.M.

Initial experience in monitoring the application of degradable starch microspheres (DSM) and chemotherapy for liver metastases.


Fleming, J.S., Britten, A.J.

The role of radionuclides in assessing hepatic haemodynamics and arterial therapy.


Blake, G.M., Gray, J.M., Zivanovic, M.A., Fleming, J.S.

The effect of between patient variation in strontium kinetics on Sr-89 dosimetry.

Journal of Nuclear Medicine, 28, 1987, 683

Flowerdew, A.D.S., McLaren, M.I., Fleming, J.S., Britten, A.J., Ackery, D.M., Birch, S.J., Taylor, I., Karran, S.J.

Liver tumour blood flow and response to arterial embolisation measured by dynamic hepatic scintigraphy.


Walmsley, B.H., Fleming, J.S., Ackery, D.M., Karran, S.J.

Non-invasive assessment of hepatic haemodynamics using radiocolloid scintigraphy.


Blake, G.M., Gray, J.M., Zivanovic, M.A., McEwan, A.J., Fleming, J.S., Ackery, D.M.

Strontium-89 radionuclide therapy : a dosimetric study using impulse response function.


Waller, D.G., Keast, C.M., Fleming, J.S., Ackery, D.M.

Measurement of glomerular filtration rate with Tc-99m DTPA - a comparison of plasma clearance techniques.


Fleming, J.S., Keast, C.M., Waller, D.G., Ackery, D.M.

Measurement of glomerular filtration rate with Tc-99m DTPA - a comparison of gamma camera methods.


Fleming, J.S., Ackery, D.M.

Editorial: Measurement of liver haemodynamics.


Gullquist, R.R., Fleming, J.S.

Error analysis by simulation studies in renography deconvolution.


Fleming, J.S., Ramsay, B., Waller, D., Ackery, D.M.,

Measurement of glomerular filtration rate with a portable cadmium telluride detector.


Qamar MI, Mountford R, Jackson PC, Davies ER, Read AE

Relationship between gastric emptying and superior mesenteric artery blood flow following a solid meal.

Abst Br J Radiol, 59, 1986, 827

Webb, A.J., Sinha, B., Briggs, R.J.S., Fleming, J.S., Ackery, D.M.

Does radiolabelled diphosphonate retention reflect bone metabolism in the elderly.

Age and Ageing, 15, 1986, 164-168

Fleming, J.S., Hames, T.K., Smallwood, J.

A comparison of impedance and water displacement plethysmography in the assessment of volume change in the forearm. Medical and Biological Engineering and Computing, 24, 1986, 375-378

Hutton CW, Higgs ER, Jackson PC, Watt I, Diepee PA

Tc-HMDP bone scanning in generalised osteoarthritis.

Ann Rheum Dis, 45, 1986, 622-626

Goeting, N.L.M., Fleming, J.S., Gallagher, P., Walmsley, B.H., Karran, S.J.

Alterations in liver blood flow and reticulo-endothelial function in progressive cirrhosis in the rat. Journal of Nuclear Medicine Journal of Nuclear Medicine, 27, 1986, 1751-1754

Channer KS, Jackson PC, Virgee JP

The value of eosophageal transit tests in the investigation of patients with chest pain.

Abst Br J Radiol, 59, 1986, 805-806

Jackson PC

Radionuclide Imaging: Theory and Practice

London, Farrand Press, 1986, ISBN 1-85083-003-7,

Murphy, P., Alexander, P., Kirkham, N., Fleming, J.S., Taylor, I.

The pattern of spread of blood borne tumour.


Hutton CW, Higgs ER, Jackson PC, Watt I, Dieppe PA

Tc-HMDP bone scanning in generalised osteoarthritis I: comparison of the standard radiographs and four hour bone scan image of the hand.

Ann Rheum Dis, 45, 1986, 617-621

Qamar MA, Mountford RA, Jackson PC, Davies ER, Read AE.

Gastric emptying and superiormesenteric artery (SMA) blood flow following a liquid meal.

Abst Br J Radiol, 58, 1985, 811

Davies ER, Davies JO, Jackson PC, Howe K, Pitcher EM, Sadowski CS, Stirrat GM, Sunderland CA

123 I-NDOG2 anti-placental alkaline phosphatase imaging of ovarian tumours.

Abst Brit J Can, 52, 1985, 649

Jackson PC, Davies Er, Davies JO, Pitcher EM, Sadowski C, Staddon GE, Stirrat GM, Sunderland CA

Radionuclide imaging of ovarian tumour with a radiolabelled (123I) monoclonal antibody.

Abst Phys Med Biol, 30, 1985, 95

Fleming, J.S.

A technique for motion correction in dynamic scintigraphy.


Davies JO, Davies ER, Howe K, Jackson PC, Pitcher EM, Randle B, Sadowski C, Stirrat GM, Sunderland CA

Practical applications of monoclonal antibody (NDOG2) against placental alkaline phosphatase in ovarian cancer.

J Royal Soc Med, 78, 1985, 899-905

Jackson PC, Jones M, Brimble CE, Hart J

The reduction of inter- and intra-observer variability for defining regions of interest in nuclear medicine.

Eur J Nucl Med, 11, 1985, 186-189

Channer KS, Jackson PC, O'Brien IO, Corrall RJM, Coles DR, Davies Rhys E, Virgee JP

Oesophageal function in diabetes mellitus and its association with autonomic neuropathy.

Diabetic Medicine, 2, 1985, 378-382

Jackson PC, Pitcher EM, Davies JO, Davies ER, Sadowski CS, Staddon GE, Stirrat GM, Sunderland CA.

Radionuclide imaging ovarian tumours with a radiolabelled (I-123) monoclonal antibody (NDOG2).

Eur J Nucl Med, 11, 1985, 22-28

Davies JO, Davies ER, Howe K, Jackson PC, Pitcher EM, Sadowski CS, Stirrat GM, Sunderland CA.

Raionuclide imaging of ovarian tumours with (I-123) labelled monoclonal antibody (NDOG2) directed against placental alkaline phosphatase.

Br J Obst Gynae, 92, 1985, 227-286

Fleming, J.S., Goddard, B.A., Ackery, D.M

Contralateral correction in lateral lung radionuclide imaging in phantom and clinical studies.


Murphy, P., Fleming, J.S., Taylor, I., Alexander, P.

The efficacy of trapping of blood borne cancer cells by the organ of first encounter in experimental rat tumours.

Hellman, K., Eccles, S.A., Treatment of metastasis : problems and prospects, London, Taylor and Francis, 1985,

McLaren, M.I., Fleming, J.S., Walmsley, B.H., Karran, S.J., Taylor. I.

Dynamic liver scanning in cirrhosis.


Lewis, R.A., Fleming, J.S

Fractional deposition from a jet nebuliser : how it differs from a metered dose inhaler.

British Journal of Diseases of the Chest, 79, 1985, 361-367

Nakielny RA, Thomas WEG, Jackson PC, Jones M, Davies ER

Radionuclide evaluation of scrotal disease

Clin Rad, 35, 1984, 125-129

Fleming, J.S., Goddard, B.A.

Evaluation of techniques for stationary coded aperture three-dimensional imaging in nuclear medicine.

Nuclear Instruments and Methods in Physical Research, 221, 1984, 242-246

Hames, T.K., Condon, B.R., Fleming, J.S., Phillips, G., Holdstock, G., Howlett, P.J., Ackery, D.M., Smith, C.L.

A comparison between the use of a shadow shield whole body counter and uncollimated gamma camera in the assessment of the 7 day retention of SeHCAT.


Jackson PC, Pitcher EM, Davies ER, Davies JO, Sunderland CA, Staddon GE, Sadowski CS, Stirrat GM

Radionuclide imaging with a monoclonal antibody for the detection of ovarian cancer.

Abst Radiology, 153, 1984, (P)

Hutton CW, Dieppe PA, Higgs L, Jackson PC, Watt I

Osteoarthritis (OA) of the hand, assessment clinically, radiologically and by iostope scanning.

Abst J Rheum, 123, 1984, 141

Jackson PC, Davies ER, Russell-Rees J, Wilde P, Allen-Narker R, Watt I.

Edge dectection in radionuclide imaging, Hospital Physicists' Association Annual Conference

Abst Clin Phys Physiol Meas, 4, 1983, 95

Fleming, J.S., Ackery, D.M., Walmsley, B.H., Karran, S.J.

Scintigraphic estimation of the arterial and portal blood supplies to the liver.


Thomas WEG, Jackson PC, Cooper MJ, Burton PA, Davies ER

The correlation between serial IDA imaging and gastric mucosal change

Nucl Med Comm, 4, 1983, 163

Jackson PC, Davies ER, Goddard PR, Wilde RPH

The display of multiple images derived from emission computed assisted tomography (ECAT)

Nucl Med Comm, 4, 1983, 348-353

Thomas WEG, Nakielny R, Jackson PC, Williamson RCN, Davies ER

Scrotal scintigraphy

Nucl Med Comm, 3, 1982, 129

Jackson PC, Allen-Narker R, Wilde P, Davies ER, Russell-Rees J, Watt I

The assessment of left ventricular ejection fraction in radionuclide multiple gated acquisition studies using an edge detection algorithm.

Eur J Nucl Med, 7, 1982, 62-65

Jackson PC

The performance characteristics derived from emission computed tomographic images using a rotating head gamma camera

Int J Nucl Med Biol, 9, 1982, 134-136

Karran, S.J., Fleming, J.S., Humphries, N.L.M.

Non-invasive assessment of hepatic perfusion and of the relative arterial and portal components.

R.T. Mathie, Blood Flow Measurement in Man (),, Tunbridge Wells, Castle House Publications, 1982, 155-167

Jackson PC

The incoporation of temporal information into positron emission tomography

Phys Med Biol, 27, 1982, 165


A comparison of techniques for stationary coded aperture imaging in nuclear medicine.

Medical and Biological Engineering and Computing, 20, 1982, 7-11

Taylor, D.N., Harris, D.N.F., Condon, B.R., Ogilvie, B., Ackery, D.M., Fleming, J.S., Goddard, B.A.

Radionuclide evaluation of valvular regurgitation.


Jackson PC

The incorporation of time-of-flight measurements into positron emission tomography

Int J Nucl Med Biol, 9, 1982, 129-133

Jackson PC

Evaluating the performance of an edge detection algorithm for use in radionuclide imaging

Phys Med Biol, 8, 1982, 1045-1055

Fleming, J.S., Humphries, N.L.M., Karran, S.J., Ackery, D.M., Goddard, B.A.

In-vivo assessment of hepatic arterial and portal venous components of liver perfusion.


Condon, B.R., Buchanan, R., Garvie, N.W., Ackery, D.M., Fleming, J.S., Taylor, D.N., Hawkes, D., Goddard, B.A.

Assessment of progression of secondary bone lesions following cancer of the breast or prostate using serial radionuclide imaging.


Jackson PC

Contrast enhancement of images by inclusion of time-of-flight information into positron emission tomography

Nucl Med Comm, 2, 1981, 174-179

Jackson PC, Wilde P, Davies ER

An edge detection algorithm for use in radionuclide imaging

Eur J Nucl Med, 6, 1981, 33-38

Thomas WEG, Cooke PH, Davies ER, Jackson PC, Williamson RCN

Dynamic radionuclide scanning of the testis in acute scrotal conditions

Br J Surg, 68, 1981, 621-624

Jackson PC, Wilde P, Davies ER

Production of dynamic persistence displays using a computer

J Nucl Med Tech, 4, 1980, 162-165

Fleming, J.S.

A technique for the absolute measurement of activity using a gamma camera and computer.


Miller, J., Diffey, B.L., Fleming, J.S.

Measurement of colloid clearance rate as an adjunct to static liver imaging.


Karran, S.J., Eagles, C.J., Fleming, J.S., Ackery, D.M

In-vivo measurement of liver perfusion in the normal and partially hepatectomised rat using Tc-99m sulphur colloid.


Fleming, J.S.

Technique for contralateral subtraction in lateral lung radionuclide imaging.

Medical and Biological Engineering and Computing, 17, 1979, 751-756

Fleming, J.S.

The manufacture and properties of two dimensional position sensitive orthogonal electrode silicon surface barrier detectors. Nuclear Instruments and Methods, 150, 1978, 417-425

Fleming, J.S.

Measurement of Hippuran plasma clearance using a gamma camera.


Everett ,D.B., Fleming, J.S., Todd, R.W., Nightingale, J.M.

Gamma radiation imaging system based on the compton effect.

Proc IEE, 124, 1977, 995-1000

Fleming, J.S., Kenny, R.W.

A comparison of techniques for the filtering of noise in the renogram.



Deconvolution analysis in radionuclide renal studies.

Applications of Time Series Analysis, Southampton University Institute of Sound and Vibration Research, 1977,

Fleming JS

The Compton effect gamma camera detector system

Southampton, University of Southampton (PhD thesis), 1976,

Everett, D.B., Fleming, J.S., Todd, R.W., Nightingale, J.M.

A gamma camera using compton interactions.

Hay, G.A., Medical Images - formation perception and measurement, Bristol, John Wiley and Sons, 1976, 89-98

Kenny, R.W., Ackery, D.M., Fleming, J.S., Goddard, B.A., Grant, R.W.

Deconvolution of the scintillation camera renogram.


Gamlen, T.R., Triger, D.R., Ackery, D.M., Fleming, J.S., Grant, R.W., Kenny, R.W., MacIver, A.G., Wright, R.

Quantitative liver imaging using I-131 rose bengal as an index of liver function and prognosis.

Gut, 16, 1975, 738-743

Fleming, J.S., Nightingale, J.M.

A noise analysis in gold-n silicon surface barrier radiation detectors.

Nuclear Instruments and Methods, 127, 1975, 221-224

Burrows, P.J., Fleming, J.S., Garnett, E.S., Ackery, D.M., Colin-Jones, D.C., Bamforth, J.

Clinical evaluation of the C-14 fat absorption test.

Gut, 15, 1974, 147-150

Fleming, J.S., Orchard, P.G.

Isocentric radiotherapy treatment planning where the treatment axis is not horizontal.



A technique for the deconvolution of the renogram.



Regional lung volume assessment by transmission scintigraphy.


Misra DP, Staddon GE, Powell NL, Jackson PC

Assessment of potassium metabolism, using K-42, in cases of myxodema before and after treatment with thyroxine

Age Ageing, 3, 1974, 245-248

Hampson WG, Harris FC, Lucas HK, Roberts PH, Jackson PC, Powell NL, Staddon GE.

Failure of low dose heparin to prevent deep vein thrombosis after hip-replacement arthoplasty'

Lancet, II, 1974, 795-797


Regional ventilation assessment by transmission scintigraphy.

Acta Radiologica, 12, 1973, 416-424