non-communicable diseases: an overview (jeffrey sturchio)

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    Meeting the Challenge of

    Non-Communicable Diseases

    Dr. Jeffrey L. SturchioPresident & CEOGlobal Health Council

    Journalist to Journalist TrainingNational Press Foundation

    June 12, 2011

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    Globalization and health

    In an age of globalization and growing insecurity, health is

    everybodys business

    With the impact of global transportation and communications

    networks, a SARS outbreak in China can reverberated rapidlyfrom Canada to Cairo

    In an interconnected and interdependent world, bacteria and

    viruses travel almost as fast as e-mail messages and money

    flows.

    Gro Harlem Brundtland, former Director-General, World

    Health Organization (2005)

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    Global health matters

    Global health affects everyone disease knows no borders

    Infectious diseases such as avian influenza, tuberculosis, SARS and

    West Nile Virus can spread from one country to another

    Other health challenges such as HIV/AIDS have a major global political

    and economic impact

    Good health is the foundation for building a stable economy

    Poor health hinders ones ability to take advantage of educational

    opportunities or hold a job

    Poor health undermines countries development and trade and can

    reinforce the cycle of poverty and political instability.

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    Impact of global crises on health

    Equitable access to health care, and greater equity inhealth outcomes are fundamental to a well-functioningeconomy.Health had no say in the policies that led to

    the financial crisis or made climate change inevitable.But the health sector will bear the brunt of theconsequences.....A world that is greatly out of balancein matters of health is neither stable nor secure.

    Margaret Chan, The impact of global crises on health: money, weatherand microbes, Address at the 23rd Forum on Global Issues, Berlin,Germany, March 18, 2009.http://www.who.int/dg/speeches/2009/financial_crisis_20090318/en/

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    Non-communicable diseases

    Non-communicable diseases (NCDs) are the leading cause of deathand disability worldwide; they account for 60 percent of all deathsglobally

    People living in developing countries are more likely to develop anddie prematurely from chronic disease

    Have limited access to comprehensive health services for NCDs Live in countries that do not have effective policies for NCDs (tobacco, alcohol,

    air pollution, etc.)

    In addition to their devastating impact on health, NCDs have amajor socio-economic impact on individuals, families, communities,and countries

    There is an urgent need to raise the profile of NCDs on theinternational development agenda

    The burden of chronic disease will account for over 75 percentof deaths by 2030

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    Health Statistics and Informatics

    Ten leading causes of burden of disease,world, 2004 and 2030

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    The World Economic Forum named NCDs the third largest economic

    risk facing the globe in 2010

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    Many of the risk factors associated with NCDs are related to

    modifiable behaviors

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    SOURCE: Geneau R, Stuckler D, McKee M, et al. Raising the priority of preventing chronic diseases: a politicalprocess. Lancet 2010; 376: 1689-98.

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    Cardiovascular Diseases

    The leading cause of death worldwide, accounting for 17 million

    deaths in 2005

    Of these, 7.2 million were due to heart attacks and 5.7 million

    due to stroke

    Include coronary heart disease (heart attacks), cerebrovascular

    disease, raised blood pressure (hypertension), peripheral artery

    disease, rheumatic heart disease, congenital heart disease, and

    heart failure

    If current trends continue, WHO estimates that 23.6 million peoplewill dies from cardiovascular disease by 2030

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    Chronic respiratory diseases (CRDs)

    Include asthma, respiratory allergies, chronic

    obstructive pulmonary disease (COPD), occupational

    lung diseases, sleep apnea syndrome and pulmonary

    hypertension Collectively, CRDs account for 4 million deaths per

    year; COPD is the fourth leading cause of death

    worldwide

    Many CRDs are preventable, although they often fail

    to receive adequate attention from the health care

    system

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    Cancers

    A leading cause of death group worldwide, accounting for 7.4million deaths in 2004

    The global cancer burden has doubled in the past 30 years; by

    2020, the cancer burden of 2000 is expected to double again

    More that 70 percent of cancers occur in low- and middle-income countries

    The leading type of cancer is lung cancer, accounting for 1.3

    million deaths per year

    In less developed countries, the leading type of cancer formen is lung cancer, followed by liver cancer; the leading type

    for women is breast cancer followed by cervical cancer

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    Diabetes

    Worldwide, over 220 people had diabetes in 2004

    Nearly 80 percent of diabetes deaths occur in low- and

    middle-income countries

    WHO estimates that diabetes deaths will doublebetween 2005 and 2030

    Causes kidney failure, diabetic retinopathy, and

    diabetic neuropathy; increases the risk of heart disease

    and stroke

    43 million pre-school children worldwide are obese

    or overweight

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    60 per cent of the worlds total deaths are due to non-

    communicable diseases, many of which are preventable

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    90 per cent of people dying prematurely from NCDs live in

    developing countries

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    NCDs are among the top ten causes of causes of death in every

    income group

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    Without action, Africa will witness the largest increase in deaths

    from NCDs in 2015 (compared to 2004). South East Asia and the

    Western Pacific will have the highest absolute number of deaths.

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    Factors that contribute to the rise ofNCDs

    Rapid urbanization has led to changes in diet, physical activity,

    and environmental exposure

    Decreases in the price of animal based products, sweeteners,

    and oils over the past two decades have contributed todietary changes

    Increasing availability of tobacco products as a result of

    expanding markets and lack of protective trade policies

    Lack of knowledge about chronic disease and poor

    understanding of contributing risk factors

    Shifting patterns of behavior due to globalization and

    increased media exposure/marketing

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    Economic impact ofNCDs

    NCDs reduce the economic productivity of individuals and causemany families to fall into poverty The long-term nature of treatment and care for chronic disease results in

    significant household expenditures over prolonged periods of time andinability of the household to accumulate savings

    Indian households that include a family member with a chronic disease are 40

    percent more likely to fall into poverty The expense of treatment often deters individuals from seeking

    treatment In Nigeria, over 60 percent of cancer patients failed to complete their

    chemotherapy treatments because of the prohibitive cost of the drugs

    NCDs also have a severe impact on the economies of countries Over the next decade, China is estimated to lose over $550 billion in national

    income due to cardiovascular disease

    In Central Asia, chronic diseases may reduce workers labor effort by 7 to 30percent

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    Common myths that surround NCDs that people knowingly choose toengage in unhealthy behaviors (smoking, drinking, diet), or that chronic

    diseases related to aging are inevitable may be detrimental to collective

    action

    Policies that aim to regulate individual behavior (taxes on soft drinks,

    cigarettes) may be seen as impinging on individual agency

    Weak health information systems prevent adequate surveillance of chronic

    disease in many developing countries; without data, it is difficult to argue

    for the prioritization of NCDs based on the burden of disease

    Although international advocacy for NCDs is growing, greater efforts are

    needed on the local level to raise the profile of NCDs on national agendas

    Another myth around NCDs is that low- and middle-income countries

    should give priority to infectious diseases. However, this approach does not

    align with the burden of disease in these countries.

    Why have NCDs been neglected?

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    Interventions for NCDs

    In 2007, a Lancet Series on NCDs identified three highly cost-effective

    interventions for preventing NCDs: tobacco control, salt reduction,

    combined drug treatment for people at high risk of cardiovascular disease

    Tobacco control and salt reduction could prevent almost 14 millions deaths

    over the next decade, at a cost of less than US $0.40 per person per year

    Aspirin and generic drugs to lower blood pressure and cholesterol couldprevent 18 million deaths over the next decade, at a cost of approximately

    $1.10 per person per year

    National policies and legislation to limit the use of harmful substances,

    such as tobacco, alcohol, and unhealthy foods

    Behavior change campaigns to educate about the risks of chronic disease and

    encourage positive, healthy behaviors

    Strengthening of health systems and additional prevention, screening,

    treatment, and care services targeted to chronic disease

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    Funding for NCDs

    Funding for NCDs is severely lacking; in 2007, only 2.3 percent($503 million) of overall development assistance for health wasdedicated to NCDs Less than 15 percent of the WHOs agenda is allocated to chronic disease

    Less than 2 percent of the total health budget of the Gates Foundation andthe World Bank is allocated to chronic disease

    Currently, there is no OECD/DAC Reporting System code to trackfunds for NCDs

    In low- and middle-income countries, many governments areincreasing domestic expenditures for health, but investment inchronic disease is lacking

    However, between 2001 and 2008 donor funding to developingcountries for NCDs increased by over 600 percent. This suggests agrowing recognition and willingness to address the increasingburden of NCDs.

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    Next steps for NCDs

    High-level Meeting of the United Nations General Assemblyon the Prevention and Control of Non-communicable Diseases

    on September 19, 2011

    UNGA will focus on three major themes related to chronic

    disease: The rising incidence, developmental and other

    challenges and the socioeconomic impact of NCDs and

    their risk factors;

    Strengthening national capacities, as well asappropriate policies, to address prevention and control

    of non-communicable diseases;

    Fostering international cooperation, as well as

    coordination, to address non-communicable diseases.

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    NCD Alliance

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    NCD Alliances 10 Asks

    for the UN NCDs Summit

    1. Commit to a whole-of-government response through costed national plans for NCD

    prevention and treatment

    2. Establish an NCDs Partnership, linked to WHO, to coordinate follow up action with member

    states, other UN and multilateral agencies, foundations, NGOs and private sector

    3. Increase national and international resources for NCD prevention and treatment4. Include NCDs in future global health and development goals

    5. Accelerate implementation of Framework Convention on Tobacco Control (FCTC)

    6. Reduce dietary salt, sugar, saturated and trans-fats and harmful use of alcohol

    7. Implement strategies to encourage physical activity and improve diet

    8. Strengthen health systems through integration of NCD prevention and treatment

    9. Increase access to affordable, quality-assured essential medicines and technologies to

    prevent and treat cancer, cardiovascular disease, chronic respiratory disease and diabetes,including vaccines and palliative care

    10. Establish a high level Accountability Commission on NCDs with cross sector

    representation to monitor Summit commitments.

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    Key dates

    WHO/ UNDESA Regional Summit Consultations South-East Asia (14-17 Feb, Dhaka, Bangladesh)

    Americas (24-25 February, Mexico City, Mexico)

    Western Pacific (25-27 March, Seoul, South Korea)

    Africa: TBD

    NCD Alliance Side Event: 55th Session of the Commission on the Status of Women,

    22 Feb4 Mar, New York Partners in Health / NCD Alliance Conference on NCDs of the Bottom Billion, 2-3

    March, Harvard University

    Oxford Health Alliance Annual Meeting on NCDs, 14-15 April 2011, Oxford, UK

    NCDnet Global Forum, 27 April, Moscow

    Russia Ministerial Conference on NCDs, 28-29 April, Moscow

    64th World Health Assembly, 16-25 May, Geneva

    Global Health Council Annual Conference (Theme: NCDs), 13-17 June, Washington,DC

    UN civil society consultation, June 16

    UN High-Level Meeting, 19-20 September 2011 in New York Three RoundtableSessions

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    A role for public/private partnerships

    Private sector companies can also make contributions to

    health and development by building partnerships to address

    these challenges

    Working together, we can achieve more than any singleorganization or country can do on its own

    Public/private partnerships offer an important mechanism

    that works to combine the complementary resources and

    expertise of the public and private sectors to achieve health

    goals

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    The value of collaboration

    The marketplace is not the answer to all questions facing

    society. Likewise, the public sector cannot solve all social

    problems. But the combination of public and private efforts,

    when harnessed together, in an effort to achieve a clear and

    shared health objective, provides a powerful force that

    exceeds the sum of its separate efforts.

    Dr. William H. Foege, in Ethics and the Pharmaceutical Industry

    (2005)

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    Framework for Corporate Pledges to

    Support NCD Prevention & Control

    Health Promotion and Risk Prevention

    1) Nutrition &

    healthy diets

    (A,H)

    2) Physical activity

    & sports (B,H)

    3) Tobacco control

    (C,D,H)

    4) Alcohol

    responsibility

    (C,D, H)

    5) Health education &

    wellness initiatives

    (C,D, G, H, I)

    Reformulation

    Marketing

    Portion size

    Other

    School/youth

    Urban design

    Other

    Smoke free

    workplaces

    Cessation support

    Other

    Counsel/support

    Other

    Awareness

    Risk management

    Wellness incentives

    Other

    Health System Strengthening

    6) Medicines &

    Vaccines (E)

    7) Patient diagnosis

    & Treatment

    (E,F)

    8) Healthcare

    professional

    training (D,F,G)

    9) Patient monitoring

    & follow-up (D,G)

    10) Governance (I)

    R&D for innovative

    medicines for NCDs

    Affordable &

    accessible treatment

    Other

    Leveraging primary

    care infrastructure

    Innovative delivery

    models

    Other

    Building networks

    On-line training

    Internships

    Other

    Remote check-ups

    Disease management

    Other

    Self-regulatory codes

    Industry commitments

    Best practices

    Other

    A. Food/beverage, food service & agriculture B. Sporting Goods

    C. Employers D. Health Insurers & healthcare providers

    E. Pharmaceuticals F. Medical devices & diagnostics

    G. Information &/Communications Technologies (ICTs) H. Media

    I. Cross-industry J. Other

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    The way forward

    We need to find the best solutions and scale them up --across borders, across sectors, and throughcollaboration and cooperation among all stakeholders

    Progress is possible -- and there have been encouragingdevelopments in the past several years with respect todealing effectively with major global health issues

    Continued partnerships in global health provide thebest way to build on this momentum -- and offer the

    best hope for those living with both infectious andchronic diseases in the developing world