NIHR Grant NIHR Grant ProgrammeProgramme

RP-PG-0707-10012 RP-PG-0707-10012

Executive Team Meeting Executive Team Meeting

28 September 2010 28 September 2010

Glanville Centre, Salisbury Glanville Centre, Salisbury District Hospital District Hospital

Agenda Agenda 9.00 – 9.109.00 – 9.10 CoffeeCoffee

9.10 – 9.309.10 – 9.30 Intro and 18/12 reportIntro and 18/12 report Ian SwainIan Swain

9.30 – 9.30 – 10.1510.15

WP1 progress to dateWP1 progress to date Damian Damian Jenkinson/Gabrielle Mc Jenkinson/Gabrielle Mc HughHugh

10.15 – 10.15 – 11.0011.00

WP2 progress to dateWP2 progress to date Anand Pandyan/Sybil Anand Pandyan/Sybil FarmerFarmer

11.00 – 11.00 – 11.3011.30

CoffeeCoffee

11.30 – 11.30 – 12.3012.30

WP3 progress to dateWP3 progress to date Jane Burridge, Ann-Jane Burridge, Ann-Marie Hughes, Sara Marie Hughes, Sara DemainDemain

12.30 – 12.30 – 13.3013.30

LunchLunch

13.30 – 13.30 – 15.0015.00

Preparation for CT Preparation for CT applicationapplication-Due on 1/3/11Due on 1/3/11-Dates for WP Dates for WP informationinformation

All All

15.00 – 15.00 – 15.3015.30

TeaTea

15.30 – 15.30 – 17.00 17.00

CT application CT application continuedcontinued

AllAll

17.0017.00 DONMDONM

NIHR PROGRAMME GRANT v3 09       10       11      

Version 2 if trial not funded                  

Start date 1/1/09 (Q1) Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

Task                        

WP1 - Review of existing services                        

Identification of centres                        

Qualitative design phase workshop                        

Drafting of questionnaire                        

 Piloting of questionnaire                        

Analysis of pilot results                        

Modification of questionnaire                        

Main questionnaire and follow up                        

Analysis of results                        

Producing review for publication                        

Updating existing services review                        

Reports      20/11/

09      20/11/

1001/03/

11    20/11/

10

WP2 - Literature review09Q1 Q2 Q3 Q4

10Q1 Q2 Q3 Q4

11Q1 Q2 Q3 Q4

Planning the review                        

Conducting the searches                        

Selection of articles                        

Review process                        

Peer review by management team                        

Audit of article selection                        

Audit of reviewed articles                        

Updating of reviews                        

Publication of systematic reviews                        

Reports      20/11/2009      

20/11/2010

01/03/2011    

20/11/2010

WP3 - Acceptability of ATs09Q1 Q2 Q3 Q4

10Q1 Q2 Q3 Q4

11Q1 Q2 Q3 Q4

Ethical application and approval                        

Design, running and evaluating the interactive exhibition                        

Focus groups                        

Focus group analysis                        

Questionnaire design                        

Questionnaire validation                        

Questionnaire data collection                        

Questionnaire analysis                        

Field trials design                        

Dissemination                        

Reports      20/11/2009      

20/11/2010

01/03/2011    

20/11/2010

WP4 - Clinical Trials09Q1 Q2 Q3 Q4

10Q1 Q2 Q3 Q4

11Q1 Q2 Q3

Q4/Q1 2012

WP4 Phase 1                      

AT selection procedure and consultation                        

Decision on what ATs to include in Phase 2                        

Trial design                        

WP4 Phase 2                        

JDs and advert for therapists                        

WP6 - Dissemination                        

Annual/Financial Report      01/03/2010  

01/09/2010

01/03/2011    

01/03/2012

Trial design report (major report)                15/03/2

011      

Presenting at key meetings                        

Writing final report                        

Publishing book/special edition                        

International conference                        

AHP processAHP process

• Seminars and workshops given by Maarten Seminars and workshops given by Maarten IjzermanIjzerman

• Its been used in Healthcare for the last 10 yearsIts been used in Healthcare for the last 10 years• Combines clinical experience with systematic Combines clinical experience with systematic

reviews.reviews.• Define attributes, both primary and secondary Define attributes, both primary and secondary

and assign attribute weights to themand assign attribute weights to them• Identify alternative treatmentsIdentify alternative treatments• Undertake comparisons in order to get Undertake comparisons in order to get

performance weights.performance weights.• Done using Expert choice softwareDone using Expert choice software

AttributesAttributesDetermined by Exec team in March and Determined by Exec team in March and

confirmed with Steering Committeeconfirmed with Steering Committee• FunctionFunction• ComfortComfort• RisksRisks

– Short termShort term– Long termLong term

• Daily effort (patient)Daily effort (patient)– Time Time – ComplexityComplexity

• Impact on Health ServiceImpact on Health Service– TimeTime– ComplexityComplexity

Alternative TreatmentsAlternative Treatments

• Peripheral FESPeripheral FES• Central/cortical stimulationCentral/cortical stimulation• CIMTCIMT• RoboticsRobotics• Active orthoticsActive orthotics• BiofeedbackBiofeedback• VR including WiiVR including Wii

Pair wise comparisonsPair wise comparisonsUndertaken by Steering Committee as Undertaken by Steering Committee as

expert groupexpert group• In order to get performance weightsIn order to get performance weights• E.g. how would you rate FES and CIMT E.g. how would you rate FES and CIMT

in terms of comfort.in terms of comfort.• Replace performance weights with Replace performance weights with

objective data from WP2objective data from WP2• In absence of objective data use expert In absence of objective data use expert

opinion from Steering Committeeopinion from Steering Committee• Use subjects from WP3 to give patient Use subjects from WP3 to give patient

perspective to attribute weightsperspective to attribute weights

Combining dataCombining data

• Use results of AHP process, Use results of AHP process, professionals and patientsprofessionals and patients

• Use HE informationUse HE information• Use WP1 to look at prevalence of Use WP1 to look at prevalence of

impairmentsimpairments• Come to final conclusion - re two Come to final conclusion - re two

selected interventions and use selected interventions and use WP1 to determine control group.WP1 to determine control group.

www.atrasprojewww.atrasproject.orgct.org