NIH Funding Opportunitiesfor Economists

C-FARE SessionC-FARE Session

AAEA Annual MeetingAAEA Annual MeetingMontrealMontreal

July 26, 2003July 26, 2003

Rachel A. Nugent, Ph.D.Rachel A. Nugent, Ph.D.

Fogarty International CenterFogarty International Center

National Institutes of HealthNational Institutes of Health

Overview of Presentation Opening the black box: what is NIH?Opening the black box: what is NIH? Why consider applying for funding at Why consider applying for funding at

NIH?NIH? What to do before applyingWhat to do before applying After you applyAfter you apply Opportunities for economists at NIHOpportunities for economists at NIH Contact me with questionsContact me with questions

Office of the DirectorOffice of the Director

National Instituteon Alcohol Abuseand Alcoholism

National Instituteon Alcohol Abuseand Alcoholism

National Instituteof Arthritis andMusculoskeletal

and Skin Diseases

National Instituteof Arthritis andMusculoskeletal

and Skin Diseases

National CancerInstitute

National CancerInstitute

National Instituteof Diabetes andDigestive and

Kidney Diseases

National Instituteof Diabetes andDigestive and

Kidney Diseases

National Instituteof Dental andCraniofacial

Research

National Instituteof Dental andCraniofacial

Research

National Instituteon Drug Abuse

National Instituteon Drug Abuse

National Instituteof Environmental Health Sciences

National Instituteof Environmental Health Sciences

National Instituteon Aging

National InstituteNational Instituteon Agingon Aging

National Instituteof Child Health

and HumanDevelopment

National InstituteNational Instituteof Child Healthof Child Health

and Humanand HumanDevelopmentDevelopment

National Institute onDeafness and Other

CommunicationDisorders

National Institute onDeafness and Other

CommunicationDisorders

National EyeInstitute

National EyeInstitute

National HumanGenome Research

Institute

National HumanGenome Research

Institute

National Heart,Lung, and Blood

Institute

National Heart,Lung, and Blood

Institute

National Instituteof Mental Health

National Instituteof Mental Health

National Instituteof NeurologicalDisorders and

Stroke

National Instituteof NeurologicalDisorders and

Stroke

National Instituteof General

Medical Sciences

National Instituteof General

Medical Sciences

National Instituteof Nursing Research

National Instituteof Nursing Research

National Libraryof Medicine

National Libraryof Medicine

Center for InformationTechnology

Center for InformationTechnology

Center for Scientific Review

Center for Scientific Review

National Centerfor Complementary

and AlternativeMedicine

National Centerfor Complementary

and AlternativeMedicine

National Instituteof Allergy and

Infectious Diseases

National Instituteof Allergy and

Infectious Diseases

National Centerfor ResearchResources

National Centerfor ResearchResources

Clinical CenterClinical Center

National Center on Minority Health andHealth Disparities

National Center on Minority Health andHealth Disparities

National Institute of Biomedical Imagingand Bioengineering

National Institute of Biomedical Imagingand Bioengineering

FogartyInternational

Center

FogartyFogartyInternationalInternational

CenterCenter

National Institutes of Health

Why apply for funding at NIH?

New emphasis on social and behavioral New emphasis on social and behavioral researchresearchIncrease in inter-disciplinary researchIncrease in inter-disciplinary research$2.5 billion in behavioral and social science $2.5 billion in behavioral and social science research throughout NIHresearch throughout NIH

How NIH grant funding works 80% investigator-initiated proposals80% investigator-initiated proposals

Three deadlines per year on a revolving Three deadlines per year on a revolving basis basis

Fixed receipt dates: Feb 1, June 1, Oct 1Fixed receipt dates: Feb 1, June 1, Oct 1 20% respond to solicitations: PAs and RFAs20% respond to solicitations: PAs and RFAs Referred to appropriate IC and peer reviewedReferred to appropriate IC and peer reviewed IC determines funding lineIC determines funding line

Main types of research grants for investigators:

R01R01 - Research Project Grant - Research Project Grant

R03R03 - Small Grant - Small Grant

R21R21 – Planning Grant – Planning Grant

K01K01 – Research Career Development – Research Career Development AwardAward

Special funding initiatives: RFA: Request for ApplicationsRFA: Request for Applications

PA: Program AnnouncementPA: Program Announcement How NIH asks researchers to How NIH asks researchers to

consider certain topics or areas consider certain topics or areas Also how NIH notifies researchers Also how NIH notifies researchers

that funding mechanisms (e.g., that funding mechanisms (e.g., R03s) are availableR03s) are available

RFA versus PA:

RFARFA PAPA

Funds set aside for Funds set aside for projects?projects?

YesYes Usually Usually notnot

Special application Special application deadlines?deadlines?

YesYes Usually Usually notnot

How long active?How long active? Until Until deadlinedeadline

3 years3 years

Special review panel?Special review panel? OftenOften Usually Usually notnot

Is it worth the effort?

True, NIH is very competitiveTrue, NIH is very competitive Grant applications are demandingGrant applications are demanding Most senior NIH researchers failed Most senior NIH researchers failed

initially, but eventually succeededinitially, but eventually succeeded But, you control the scienceBut, you control the science NIH support is generous and prestigiousNIH support is generous and prestigious

Things to do before applying Identify target IC and relevant program staffIdentify target IC and relevant program staff Get advice from program staff about research Get advice from program staff about research

plan and funding mechanismsplan and funding mechanisms Review the website for:Review the website for:

Research recently fundedResearch recently funded Current RFAs and PAsCurrent RFAs and PAs Information for applicantsInformation for applicants

CRISPCRISPCComputer omputer RRetrieval of etrieval of IInformation on nformation on SScientificcientific PProjects rojects

Database of federally-funded biomedical researchDatabase of federally-funded biomedical research

National Institutes of Health (NIH),National Institutes of Health (NIH), Substance Abuse and Mental Health Services (SAMHSA),Substance Abuse and Mental Health Services (SAMHSA), Health Resources and Services Administration (HRSA),Health Resources and Services Administration (HRSA), Food and Drug Administration (FDA),Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDCP),Centers for Disease Control and Prevention (CDCP), Agency for Health Care Research and Quality (AHRQ),Agency for Health Care Research and Quality (AHRQ), Office of Assistant Secretary of Health (OASH). Office of Assistant Secretary of Health (OASH).

Use CRISP to:Use CRISP to: Search for scientific concepts, emerging Search for scientific concepts, emerging

trends and techniquestrends and techniques Search for funded grant abstractsSearch for funded grant abstracts Find NIH institutes interested in your areaFind NIH institutes interested in your area Find the NIH study section that reviews Find the NIH study section that reviews

applications in your research areaapplications in your research area

http//:www.nih.gov NIH

HOME

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Watch for the GUIDE in a later

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GRANTS

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http://crisp.cit.nih.gov

CRISP

HOME

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CRISP

SEARCH

CRISP

RESULTS

CRISP

ABSTRACT

http://grants.nih.gov/grants/guide/index.htmlhttp://grants.nih.gov/grants/guide/index.htmlhttp://grants.nih.gov/grants/guide/index.htmlhttp://grants.nih.gov/grants/guide/index.html

Do more digging Find NIH grantees and ask them for:Find NIH grantees and ask them for:

Successful applicationsSuccessful applications Successful summary statementsSuccessful summary statements Unsuccessful summary statementsUnsuccessful summary statements ““Summary statement” is the written Summary statement” is the written

critique from the peer review, called “pink critique from the peer review, called “pink sheet”sheet”

Additional preparation (cont.) Work with a researcher who has been Work with a researcher who has been

through the NIH processthrough the NIH process Choose the right topicChoose the right topic

Something you knowSomething you know Something you are recognized forSomething you are recognized for Don’t go beyond what you can doDon’t go beyond what you can do

Study the “study section” Look up the rosters of recent study sections:Look up the rosters of recent study sections:

Center for Scientific ReviewCenter for Scientific Review

www.csr.nih.gov/Committees/rosterindex.aspwww.csr.nih.gov/Committees/rosterindex.asp IC-specific Divisions of Scientific ReviewIC-specific Divisions of Scientific Review

Ascertain what study section will review your Ascertain what study section will review your proposalproposal

Talk to the program officer about the study Talk to the program officer about the study section if you have any concernssection if you have any concerns

NIH Review System

What do the reviewers want to determine?What do the reviewers want to determine? SCIENTIFIC CREDIBILITYSCIENTIFIC CREDIBILITY

What does the IC want to determine?What does the IC want to determine? WILL THE WORK HAVE IMPACT AND BE WILL THE WORK HAVE IMPACT AND BE

SUCCESSFUL IF FUNDEDSUCCESSFUL IF FUNDED Who reviews?Who reviews?

Center for Scientific ReviewCenter for Scientific Review Institutes’ own review panelsInstitutes’ own review panels Special Emphasis PanelSpecial Emphasis Panel

How Does the Application Flow Through the System? Comes into CSR Comes into CSR

>65,000 >65,000

applications per yearapplications per year

>500,000,000>500,000,000

pieces of paperpieces of paper

Panel-Make Up

Scientific Review Administrator (SRA)Scientific Review Administrator (SRA) ChairpersonChairperson Panel MembersPanel Members First, second and third reviewersFirst, second and third reviewers

Review, funding decision, and after

Wait for your priority score and summary Wait for your priority score and summary statementstatement

Contact the program officer with questionsContact the program officer with questions If unsuccessful, consider an appeal or If unsuccessful, consider an appeal or

reapplicationreapplication If successful, fulfill ALL your promises, stay in If successful, fulfill ALL your promises, stay in

touch with your program officertouch with your program officer

Human Subject ConcernsHuman Subject Concerns

http://ohrp.osophs.dhhs.gov/index.htmlhttp://ohrp.osophs.dhhs.gov/index.html

Federal Wide Assurance (FWA)Federal Wide Assurance (FWA)

The Federal Policy (Common Rule) for the protection The Federal Policy (Common Rule) for the protection of human subjects at of human subjects at Section 103(a)Section 103(a) requires that requires that each institution "engaged" in Federally-supported each institution "engaged" in Federally-supported human subject research file an "Assurance" of human subject research file an "Assurance" of protection for human subjects. The requirement to file protection for human subjects. The requirement to file an Assurance includes both "awardee" and an Assurance includes both "awardee" and collaborating "performance site" institutions.collaborating "performance site" institutions.

What’s inside the black box for economists?

National Institute for Child Health and DevelopmentNational Institute for Child Health and Development National Institute on AgingNational Institute on Aging Office of Behavioral and Social Science Research/ODOffice of Behavioral and Social Science Research/OD Fogarty International CenterFogarty International Center National Institute on Drug Abuse National Institute on Drug Abuse National Institute on Alcoholism and Alcohol AbuseNational Institute on Alcoholism and Alcohol Abuse National Institute of Mental HealthNational Institute of Mental Health

NICHD: Demographic and Behavioral Sciences Branch

Economist: Jeff Evans, Ph.D.Economist: Jeff Evans, Ph.D. Economic DemographyEconomic Demography Intergenerational TransactionsIntergenerational Transactions

https://www.nichd.nih.gov/about/cpr/dbs.htmhttps://www.nichd.nih.gov/about/cpr/dbs.htm

http://www.nichd.nih.gov/about/cpr/dbs/htm#staffhttp://www.nichd.nih.gov/about/cpr/dbs/htm#staff

NICHD (cont.)

Demographer: Rebecca Clark, Ph.D.Demographer: Rebecca Clark, Ph.D. Population and environmentPopulation and environment ImmigrationImmigration Population movementPopulation movement Demographic MethodsDemographic Methods

http://grants.nih.gov/grants/guide/pa-files/PA-98-098.html

http://grants.nih.gov/grants/guide/pa-files/PA-95-036.htmlhttp://grants.nih.gov/grants/guide/pa-files/PA-95-036.html

NIA: Behavioral and Social Research

Associate Director: Richard SuzmanAssociate Director: Richard Suzman, Ph.D., Ph.D. Individual Behavioral ProcessesIndividual Behavioral Processes Population and Social ProcessesPopulation and Social Processes

Demography and EpidemiologyDemography and EpidemiologyHealth and RetirementHealth and RetirementHealth and Social InstitutionsHealth and Social Institutions

http://www.nia.nih.gov/research/extramural/behavior/programs.htmhttp://www.nia.nih.gov/research/extramural/behavior/programs.htm

OBSSR: Behavioral and Social Science Research Chief: Virginia Cain, Ph.D.Chief: Virginia Cain, Ph.D.

Methodology and Measurement in Methodology and Measurement in Social Science Social Science ((PA-02-072))

http://grants1.nih.gov/grants/guide/pa-files/PA-02-072.htmlhttp://grants1.nih.gov/grants/guide/pa-files/PA-02-072.html

Social and Cultural Dimensions of Social and Cultural Dimensions of Health Health ((PA-02-043)PA-02-043)

http://grants.nih.gov/grants/guide/pa-files/PA-02-043.htmlhttp://grants.nih.gov/grants/guide/pa-files/PA-02-043.html

Fogarty International Center, NIHFogarty International Center, NIH

Mission:Mission:Promote and support Promote and support

scientific research and training scientific research and training internationally to reduce disparities in internationally to reduce disparities in

global health.global health.

“Science for Global Health”

Fogarty International Center International Studies in Health and Economic DevelopmentInternational Studies in Health and Economic Development

(ISHED) (ISHED)http://grants.nih.gov/grants/guide/rfa-files/RFA-TW-01-001.htmlhttp://grants.nih.gov/grants/guide/rfa-files/RFA-TW-01-001.html

Health, environment and economic development (HEED)Health, environment and economic development (HEED)http://grants2.nih.gov/grants/guide/rfa-files/RFA-TW-03-005.htmlhttp://grants2.nih.gov/grants/guide/rfa-files/RFA-TW-03-005.html

International Research Scientist Development Award (IRSDA) International Research Scientist Development Award (IRSDA) K01 K01

http://grants.nih.gov/grants/guide/pa-files/PAR-02-041.htmhttp://grants.nih.gov/grants/guide/pa-files/PAR-02-041.htm

International Studies in Health and Economic Development

Purpose: R01 research grants to examine Purpose: R01 research grants to examine and establish the scientific basis for linkages and establish the scientific basis for linkages between health and economics; including between health and economics; including microeconomic behavior, health systems microeconomic behavior, health systems analysis, health financing, macroeconomic analysis, health financing, macroeconomic impacts and measuresimpacts and measures

International Studies in Health and Economic Development

11 research grants in FY 2001-2005, 5 full 11 research grants in FY 2001-2005, 5 full awards and 6 development awardsawards and 6 development awards

Examining links between health and Examining links between health and economic outcomeseconomic outcomes

4 of the full awards examine impacts of 4 of the full awards examine impacts of nutrition on cognitive and economic outcomesnutrition on cognitive and economic outcomes

ISHED (cont.)

3 awards examining impact of HIV/AIDS on 3 awards examining impact of HIV/AIDS on economic outcomeseconomic outcomes

Other studies looking at impacts of iron Other studies looking at impacts of iron supplementation, micronutrient deficiency and supplementation, micronutrient deficiency and education intervention on multiple physical education intervention on multiple physical and economic pathwaysand economic pathways

Health, Environment and Economic Development (HEED)

Objective: Objective: support interdisciplinary, international support interdisciplinary, international research collaborations on the linkages research collaborations on the linkages among health, environment, and among health, environment, and development in developing countriesdevelopment in developing countries

3 million children die from environmentally

related causes each year.

Over 1 million people die each year from

work-related diseases and injuries.

Over 800 million people in the

world are food insecure.

80-90% of diahhreal cases are related to

environmental degradation.

Children in mega-cities receive

2-8 times WHO guidelines for

air pollutants.

By 2006, more than 50% of the world’s

population will live in urban areas.

2-3.5 billion people

in developing countries

rely on traditional

fuels for cooking and heating.

Inappropriate livestock-rearing practices lead to

zoonotic disease and antibiotic resistance.

Developmental grants in 2003Developmental grants in 2003 Full research grants in 2005-6Full research grants in 2005-6 Strong research capacity buildingStrong research capacity building Policy relevance and dissemination plansPolicy relevance and dissemination plans Evaluation of impactsEvaluation of impacts

Program Highlights

Health, Environment and Economic Development (HEED)

Health & Environmental Impacts of a Major Pipeline Project in Chad

Ecological Approach to Malaria Control in Brazil

Reducing SO2 Emissions in Taiyuan, China

Air Quality, Respiratory Health and Industrial Zoning in Delhi

HEED Topics

Health, Environment and Economic Development (HEED)

Factors Associated with the Use of Pesticides in southern Africa

Water Privatization Policies and Health in Chile

Impact of Leishmaniasis on HEED in Tunisia

HEED Topics

Health, Environment and Economic Development (HEED)

Career Development Award – K01

Open to U.S. post-docs and junior facultyOpen to U.S. post-docs and junior faculty Four years of salary support to develop global Four years of salary support to develop global

health research careerhealth research career Develop a mentored training and research Develop a mentored training and research

planplan Exs: Evaluation of Progresa program, Exs: Evaluation of Progresa program,

economic impact of AIDS funerals, economic impact of AIDS funerals, transmission of SFV through bushmeattransmission of SFV through bushmeat

growing Issue: Obesity NIH Task Force formed in April 2003 to NIH Task Force formed in April 2003 to

design obesity research agendadesign obesity research agenda Issue will receive substantial fundingIssue will receive substantial funding Trans-NIH and cross-disciplinaryTrans-NIH and cross-disciplinary

Building a Framework for Organizing and Coordinating Obesity Research Activities

Identification of genetic, behavioral and environmental Identification of genetic, behavioral and environmental factors causing obesityfactors causing obesity

Understanding pathogenesis of obesity and its comorbiditiesUnderstanding pathogenesis of obesity and its comorbidities

Prevention and treatment of obesityPrevention and treatment of obesity

Policy, health services, economics, translation to practicePolicy, health services, economics, translation to practice

Enabling technologiesEnabling technologies

Development of multi-disciplinary research teams Development of multi-disciplinary research teams

NIH Obesity Research Outcome Goals (Draft 6/03)

Use knowledge of regulation of energy storage and food intake to develop new therapeutic modalities (including drugs, surgery, and other technologies) to complement lifestyle interventions

Use knowledge of mechanisms whereby obesity increases risk for co-morbidities to develop potential therapeutic approaches for ameliorating these conditions independent of weight loss

Evaluate the effectiveness and assure translation of strategies to maintain healthy weight in children and adults through behavior (activity, diet) change which can be applied in a home, school, or workplace environment

Some Sources of Information Some Sources of Information on NIH Grant Writingon NIH Grant Writinghttp://www.niaid.nih.gov/ncn/grants/default.htmhttp://www.niaid.nih.gov/ncn/grants/default.htm

http://www.nigms.nih.gov/funding/tips.htmlhttp://www.nigms.nih.gov/funding/tips.html

http://www.niddk.nih.gov/fund/grants_process/grantwriting.htmhttp://www.niddk.nih.gov/fund/grants_process/grantwriting.htm

http://deainfo.nci.nih.gov/EXTRA/EXTDOCS/gntapp.htmhttp://deainfo.nci.nih.gov/EXTRA/EXTDOCS/gntapp.htm

http://www.drugabuse.gov/Funding/Grantapps.htmlhttp://www.drugabuse.gov/Funding/Grantapps.html

http://www.nigms.nih.gov/funding/tips.htmlhttp://www.nigms.nih.gov/funding/tips.html

http://grants.nih.gov/grants/guide/notice-files/not97-010.htmlhttp://grants.nih.gov/grants/guide/notice-files/not97-010.html

Feel free to contact:

Program officer: Dr. Rachel NugentProgram officer: Dr. Rachel Nugent nugentra@mail.nih.govnugentra@mail.nih.gov 301-496-8733301-496-8733 For further information: For further information:

http://www.nih.gov/fic/programs/econ.htmlhttp://www.nih.gov/fic/programs/econ.html