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Global Excellence in Action Graduate School of Interdisciplinary New Science Toyo University Graduate School of Interdisciplinary New Science Toyo University 2100, Kujirai, Kawagoe, Saitama 3508585, Japan Tel: +81 49 239 1313 Fax: +81 49 231 5117 Email: [email protected] URL: http://www.toyo.ac.jp/site/englishglns/

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Page 1: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

Global  Excellence  in  Action  Graduate  School  of  Interdisciplinary  New  Science  

Toyo  University  

Graduate  School  of  Interdisciplinary  New  Science  Toyo  University  

2100,  Kujirai,  Kawagoe,    Saitama  350-­‐8585,  Japan  Tel:  +81  49  239  1313  Fax:  +81  49  231  5117  E-­‐mail:  [email protected]  URL:  http://www.toyo.ac.jp/site/english-­‐glns/  

 

Page 2: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

 

Course  of  Bio-­‐Nano  Science  Fusion  Graduate  School  of  Interdisciplinary  New  Science  Toyo  University  

Foreword    Following   the   great   success   of   the   Doctoral   Course,   which   was   opened   in   April   2007,   the  Graduate  School  of  Interdisciplinary  New  Science,  Toyo  University,  started  the  Bio-­‐Nano  Science  Fusion  Master  Course  in  April  2011.  Its  aim  is  to  surge  ahead  in  bio  and  nanotechnology  research,  creating   new   interdisciplinary   realms.  We   provide   a   unique   curriculum   such   as  Workshops   on  advanced  equipment  and  Web  educational  programmes  as  well  as  lectures.  The  Graduate  School  also   organises   international   symposia   and   seminars   for   young   researchers.   The   students   carry  out  advanced  research  on  nanoscience/nanotechnology,  bioscience/biotechnology  and  bio-­‐nano  fusion  in  collaboration  with  the  Bio-­‐Nano  Electronics  Research  Centre,  Toyo  University.    

Supervisors                                                                

                                               

Tatsuro  Hanajiri    Design  and  fabrication  of  nanoscale  electron  devices        I  am  currently  studying  the  physics  of  nanoscale  electron  devices   and   am   interested   in   its   application   to  nanoelectronics.   I   have   studied   the   electric   properties   of  thin   SOI   films   and   the   structures   of   SOI  MOSFETs   with  decanano   scale   gates.   I   propose   fully   inverted   (FI)   SOI  MOSFETs   with   ultra-­‐thin   SOI   films   and   novel   fully  depleted  (FD)  SOI  MOSFETs.  

Hisao  Morimoto    Self-­‐organisation/nonlinear  dynamics  of  nano/micro  materials        I   am   interested   in   self-­‐organisations,   phase   transitions,  and   non-­‐linear   dynamics   of   nano/micro   materials  disperse   systems   such   as   suspensions,   in   which  nano/micro   particles,   carbon   nanotubes,   fullerenes   or  biological   cells   are   dispersed.   I   am   also   interested   in  bio-­‐nano   fusion   technologies   utilising   the   above  phenomena   induced   in   nano/micro   materials   disperse  systems.  

Sakthi  Kumar    Bio-­‐nano  fusion/nanotechnology/  biomaterials        I   am   interested   in   the   research   work   based   on   fusion   of  different   science   fields,   namely   physics,   chemistry   and  biotechnology.  I  focus  on  research  themes  such  as  (a) Nano   drug   delivery,   aptamer   (DNA   and   RNA   based)  

sensors  and  bio/chemical  sensors.    (b) Carbon   nanotubes,   nano   particles   and   quantum   dots  

for   solar   cell   applications   and  plasma  processing   thin  films.  

Yoshikata  Nakajima    Nanotechnology/Nanomaterials  Bio-­‐nano  fusion        I  am  interested  in  advanced  materials  for  future  electron  devices   such   as   silicon-­‐on-­‐insulator   (SOI)   wafers,  silicon-­‐on-­‐quartz   (SOQ)   and   silicon   nano   dots,   and  micro-­‐particles  and  biological   cells  dispersed   in   solution.  My   study   also   focuses   on   the   design   and   fabrication   of  high-­‐resolution   bio-­‐nano   analytical   systems   by   utilising  the  advanced  materials.  

Toru  Mizuki    Bio-­‐nano  fusion/Biotechnology          I  am  interested  in  the  interactions  between  biomolecules  such   as   protein,   peptide   and   DNA,   and   nano/micro  materials   such   as   CNTs,   fullerenes   and   magnetic  materials.   I   am   currently   focusing   on   bio-­‐nano   fusion  research   such   as   analysis   of   the   function   of   proteins  immobilised  on  nano/micro  materials  and  acceleration  of  the  enzyme  activity  using  a  rotational  magnetic  field.  

Page 3: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

Global  Excellence  in  Action  Graduate  School  of  Interdisciplinary  New  Science  

Toyo  University  

Admission  policy    The   Graduate   School   of   Interdisciplinary   New   Science,   Toyo   University,   accepts   motivated  Master   and   Doctor   Course   students   from   all   over   the   world   and   creates   internationally  advanced   researchers   in   the   fields   of   bioscience,   nanotechnology  and  bio-­‐nano   fusion   science  and  technology,  the  latter  being  one  of  the  most  important  subjects  in  the  21st  Century.    

 Supervisors        

 

 

 

 

 

 

 

     

 

 

 

   

 

 

 

 

 

Visiting  Professors            

 

           

Leonid  Kalachev  University  of  Montana  

Yoshio  Bando  NIMS  

Toru  Kobayashi  JAMSTEC  

Shigeru  Deguchi  JAMSTEC  

Akira  Inoue    Extremophiles  Fusion  of  biomolecules/nanoparticles        I   am   interested   in  microorganisms   (extremophiles)   living  under   extreme   environments   such   as   high   temperature,  alkaline   pH,   organic   solvents   etc.   These  microorganisms  have  high  potential  activities  producing  new  enzymes  and  decomposing  chemical  substances.   I  am  also   focusing  on  the  fusion  of  biotechnology  and  nanotechnology.  

Toru  Maekawa    Self-­‐organisation/self-­‐assembly  in  nano/micro  systems        I   am   very   much   interested   in   pattern   formations,  synchronisation   and   chaos   created   via  self-­‐organisation/self-­‐assembly,   which   are   induced   in  nano/micro   systems.   Fluctuations,   surface   effects   and  quantum   effects,   in   particular,   become   significant   on  nanometre   scales,   which   makes   nano   systems  completely  different  from  our  macroscopic  world.  

Ron  Usami    Screening  and  application  of  extremophiles        Extremophiles  are  microorganisms  which  grow  in  extreme  environments   where   other   organisms   are   difficult   to  survive.   A   great   attention   has   recently   been   paid   to  extremophiles.   I   am   developing   several   new  methodologies  for   isolating  valuable  microorganisms  and  carrying  out  analysis  of  their  functions  and  genes.  

Takashi  Uchida    Growth  and  application  of  carbon-­‐based  nanostructures        I   am   interested   in   the   research   work   related   to  carbon-­‐based  nanostructures  such  as  carbon  nanotubes,  carbon  nanowalls  and  endohedral   fullerenes.   I   focus  on  research  themes  such  as  (a)  Equipment  development-­‐chemical   vapour  deposition  systems,  electron  cyclotron  resonance  ion  source.  (b)   Growth-­‐carbon   nanotubes,   carbon   nanowalls,  endohedral  fullerenes.  

P.V.  Mohanan  Sree  Chitra  Tirunal  Institute  for  Medical  

Sciences  and  Technology  

Sir  Harry  Kroto  Florida  State  University  

Daniel  Morse  UCSB  

Sir  John  Walker  University  of  Cambridge  

Régine  Perzynski  Université  Paris  6  

Nicole  Grobert  University  of  Oxford  

Raymond  Whitby  University  of  Brighton  

Page 4: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

 

Course  of  Bio-­‐Nano  Science  Fusion  Graduate  School  of  Interdisciplinary  New  Science  Toyo  University  

Curriculum  (Master  Course)    Year Type   Title   Units  

1  

Lectures  

Introduction  to  bio-­‐nano  science  fusion   2  

English  for  science  and  technology   2  

Fundamental  mathematics   2  

Fundamental  physics   2  

Fundamental  chemistry   2  

Fundamental  biotechnology   2  

Extremophiles   2  

Nanoelectronics   2  

Nano  materials   2  

Bio  materials  and  nanotechnology   2  

Microbiology   2  

Bio  nano  science   2  

Advanced  nano  science  and  nanotechnology   2  

Workshops  

Workshop  on  advanced  equipment  I   2  

Workshop  on  advanced  equipment  II   2  

Workshop  on  advanced  equipment  III   2  

Workshop  on  advanced  equipment  IV   2  

Web  programme   Web  education  I   2  

Research  Bio-­‐nano  science  fusion  seminar  I  and  II   4  

Bio-­‐nano  science  fusion  research  I  and  II   4  

2  Web  programme   Web  education  II   2  

Research  Bio-­‐nano  science  fusion  seminar  III  and  IV   4  

Bio-­‐nano  science  fusion  research  III  and  IV   4  

 Web  educational  programmes:  GEOSET  TOYO    We  produce  in  collaboration  with  Sir  Harry  Kroto  web  educational  programmes  named  “Global  Educational  Outreach  for  Science,  Engineering  and  Technology,  Toyo  University”  abbreviated  to  “GEOSET  TOYO”.  Students  also  participate  in  the  production  of  GEOSET  TOYO  programmes.  Some  typical  programmes  are  listed  below;    

Type Programmes   Level  Lecture  +  ppt  

+  video  Fundamental  science:  Classical  mechanics  

(Outline,  philosophy,  history)  Undergraduate  (UG)  Graduate  (Grad)  

Lecture  +  ppt  +  video  

Fundamental  science:  Classical  mechanics  (Experimental  verification)   UG,  Grad  

Lecture  +  ppt  +  video  

Fundamental  science:  Electromagnetism  (Outline,  philosophy,  history)   UG,  Grad  

Lecture  +  ppt   Fundamental  science:  Electromagnetism  (Maxwell  equation)   UG,  Grad,  PD  

Experiment  +  ppt  +  video  

Observation  of  nanostructures  by  electron  microscopes   UG,  Grad,  PD  

Experiment  +  ppt  +  video  

Observation  of  nanostructures  by  scanning  probe  microscopes   UG,  Grad,  PD  

Seminar  +  ppt  +  video  

Room  temperature  growth  of  compound  semiconductors  learning  from  sea  creatures  

Professor  Daniel  Morse  

UG,  Grad,  PD,  Researchers  (R)  

Seminar  +  ppt  +  video  

Sir  Harry  Kroto’s  International  Seminar  for  Young  Scientists     UG,  Grad,  PD,  R  

Video   Introduction  to  California  NanoSystems  Facilities  and  equipment   UG,  Grad,  PD,  R  

Video   Visit  to  the  Royal  Society  Great  scientists   UG,  Grad,  PD,  R  

Video   Sir  Harry  Kroto’s  Seminar  for  Junior  Students   Primary,  Junior-­‐high  and  High  School  

Page 5: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

Global  Excellence  in  Action  Graduate  School  of  Interdisciplinary  New  Science  

Toyo  University  

Facilities  and  equipment    State-­‐of-­‐the-­‐art   facilities   and   equipment   are   installed   at   the   Bio-­‐Nano   Electronics  Research  Centre,  which  Master  and  Doctor  Course  students  can  use  for  their  research.  A  unique   course   such   as   “Workshops   on   advanced   equipment”   is   included   in   the  curriculum  for  Master  Course  students.

                                                                                 

  Nanostructures  Processing  Room   Lithography  Room     Nanoelectronics  Super  Clean  Rooms    

  Incubation  Laboratory   DNA  Sequencer     Biotechnology  Clean  Rooms    

  Transmission  Electron  Microscope   Scanning  Electron  Microscopes  

  SQUID   Scanning  Probe  Microscope  

Page 6: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

 

Course  of  Bio-­‐Nano  Science  Fusion  Graduate  School  of  Interdisciplinary  New  Science  Toyo  University  

Events    The  Graduate  School  organises  and  holds  international  symposia,  seminars,  workshops,  etc.  for  the  students.  The  students  also  participate  in  the  events;  e.g.,  they  present  their  latest  results  at  international  symposia  and  seminars.  International  Symposia  on  Bioscience  and  Nanotechnology                                          International  Seminars  for  Young  Scientists  (overseas)                  International  Seminars  for  Young  Scientists  (Kawagoe  Campus)                      

Page 7: New pamphlet 2015 - Toyo University · 2018. 12. 10. · Global&Excellence&in&Action& Graduate&School&of&Interdisciplinary&New&Science& Toyo&University& Facilities&andequipment& &

Global  Excellence  in  Action  Graduate  School  of  Interdisciplinary  New  Science  

Toyo  University  

Sir  Harry  Kroto’s  Seminars  for  Young  Scientists  (Kawagoe  Campus)                            Recent  publications  Nanoscience/nanotechnology    

A.C.   Poulose,   S.   Veeranarayanan,   M.S.   Mohamed,   Y.   Nagaoka,   R.R.   Aburto,   T.   Mitcham,   P.M.   Ajayan,   R.R.  Bouchard,  Y.  Sakamoto,  Y.  Yoshida,  T.  Maekawa  and  D.S.  Kumar,  Multi-­‐stimuli   responsive  Cu2S  nanocrystals  as  trimodal  imaging  and  synergistic  chemo-­‐photothermal  therapy  agents,  Nanoscale  7,  8378-­‐8388  (2015).  DOI:  10.1039/C4NR07139E  

N.  Chauhan,  V.  Palaninathan,  S.  Raveendran,  A.C.  Poulose,  T.  Nakajima,  T.  Hasaumra,  T.  Uchida,  T.  Hanajiri,  T.  Maekawa  and  D.S.  Kumar,  N2-­‐plasma  assisted  one-­‐step  alignment  and  patterning  of   graphene  oxide  on  SiO2/Si  substrate  via  Langmuir-­‐Blodgett  technique,  Adv.  Mater.  Interfaces  2,  1400515  (2015).  DOI:  10.1002/admi.201400515  

A.  Baliyan,  Y.  Nakajima,  T.  Fukuda,  T.  Uchida,  T.  Hanajiri  and  T.  Maekawa,  Synthesis  of  an  ultradense   forest  of  vertically   aligned   triple-­‐walled   carbon   nanotubes   of   uniform   diameter   and   length   using   hollow   catalytic  nanoparticles,  J.  Am.  Chem.  Soc.  136,  1047-­‐1053  (2014).  DOI:  10.1021/ja410794p  

T.   Yamada,   T.   Hanajiri   and   T.   Toyabe,   Modeling   of   drain   electric   flux   passing   through   the   BOX   layer   in   SOI  MOSFETs   -­‐   Part   I:   Preparation   for   modeling   based   on   conformal   mapping,   IEEE   Trans.   Electron   Devices   61,  3023–3029  (2014).  DOI:  10.1109/TED.2014.2325595  

Bioscience/biotechnology  H.  Shimoshige,  H.  Kobayashi,  T.  Mizuki,  Y.  Nagaoka,  A.  Inoue  and  T.  Maekawa,  Effect  of  polyethylene  glycol  on  the  formation   of   magnetic   nanoparticles   synthesized   by   Magnetospirillum   magnetotacticum   MS-­‐1,   PLoS   One   10,  e0127481  (2015).  DOI:  10.1371/journal.pone.0127481  

N.   Doukyu,   S.   Nihei.   Cholesterol   oxidase  with   high   catalytic   activity   from   Pseudomonas   aeruginosa:   Screening,  molecular  genetic  analysis,  expression  and  characterization,  J.  Biosci.  Bioeng.  (2015),  at  press.  DOI:  10.1016/j.jbiosc.2014.12.003  

R.  Watanabe  and  N.  Doukyu,  Improvement  of  organic  solvent  tolerance  by  disruption  of  the  lon  gene  in  Escherichia  coli,  J.  Biosci.  Bioeng.  118,  139-­‐144  (2014).  DOI:  10.1016/j.jbiosc.2014.01.011  

Bio-­‐nano  fusion  science/technology  B.  Sivakumar,  R.G.  Aswathy,  Y.  Nagaoka,  T.  Fukuda,  S.  Iwai,  K.  Venugopal,  K.  Kato,  T.  Maekawa  and  D.S.  Kumar,  An   ‘all   in  one’  approach  for  simultaneous  chemotherapeutic,  photothermal  and  magnetic  hyperthermia  mediated  by  hybrid  magnetic  nanoparticles,  RSC  Adv.  5,  25066-­‐25078  (2015).  DOI:  10.1039/C5RA00168D  

M.S.  Mohamed,  S.  Veeranarayanan,  H.  Minegishi,  Y.  Sakamoto,  Y.  Shimane,  Y.  Nagaoka,  A.  Aki,  A.C.  Poulose,  A.  Echigo,   Y.   Yoshida,   T.   Maekawa   and   D.S.   Kumar,   Cytological   and   subcellular   response   of   cells   exposed   to   the  type-­‐1  RIP  curcin  and  its  hemocompatibility  analysis,  Sci.  Rep.  4,  5747  (2014).  DOI:  10.1038/srep05747  

S.  Raveendran,  A.R.  Girija,  S.  Balasubramanian,  T.  Ukai,  Y.  Yoshida,  T.  Maekawa  and  D.S.  Kumar,  Green  approach  for   augmenting   biocompatibility   to   quantum   dots   by   extremophilic   polysaccharide   conjugation   and   nontoxic  bioimaging,  ACS  Sustainable  Chem.  Eng.  2,  1551–1558  (2014).  DOI:  10.1021/sc500002g  

S.  Balasubramanian,  A.R.  Girija,  R.  Sreejith,  Y.  Nagaoka,  S.  Iwai,  M.  Suzuki,  T.  Fukuda,  T.  Hasumura,  Y.  Yoshida,  T.  Maekawa   and   D.S.   Kumar,   Bacterial  exopolysaccharide   based   magnetic   nanoparticles:   A   versatile   nanotool   for  cancer   cell   imaging,   targeted   drug   delivery   and   synergistic   effect   of   drug   and   hyperthermia   mediated   cancer  therapy,  J.  Biomed.  Nanotechnol.  10,  885-­‐899  (2014).  DOI:  10.1166/jbn.2014.1820  

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Course  of  Bio-­‐Nano  Science  Fusion  Graduate  School  of  Interdisciplinary  New  Science  Toyo  University  

Hiroshi Akasu Sachiko Takahashi

Awards  and  prizes    ✓ Best  Poster  Award  (2014)     S.   Raveendran,   N.   Chauhan,   V.   Palaninathan,   T.   Maekawa   and   D.S.   Kumar,   Cancer   therapy   based   on   shape  

dependent  biocompatible  gold  hybrid  nanostructures,  The  9th  International  Conference  on  Surfaces,  Coatings  and  Nanostructured  Materials  (NANOSMAT  2014)  (2014),  Dublin,  Ireland.  

✓ IUPAC  Young  Researcher  Award  (2013)     S.  Veeranarayanan,  M.S.  Mohamed,  A.C.  Poulose,  N.  Hirosawa,  Y.  Sakamoto,  Y.  Yoshida,  T.  Maekawa  and  D.S  

Kumar,   Synergistic   targeting  of   cancer   and   associated   angiogenesis   In   vivo   using   triple-­‐targeted  drug   loaded  silica   nanoformulations   for   theragnosticst,   International   Conference   on   Frontiers   of   Polymers   and   Advanced  Materials  (ICFPAM-­‐2013)  (2013),  Auckland,  New  Zealand.  

✓ IUPAC  Young  Researcher  Award  (2013)     M.S.  Mohamed,  S.  Veeranarayanan,  A.C.  Poulose,  Y.  Nagaoka,  Y.  Yoshida,  T.  Maekawa  and  D.S  Kumar,  Fe3O4  

core-­‐silica   shell   nanoclusters   based   multimodal   treatment   strategy   for   drug   resistant   breast   cancers,  International   Conference   on   Frontiers   of   Polymers   and   Advanced  Materials   (ICFPAM-­‐2013)   (2013),   Auckland,  New  Zealand.  

✓ Tasilo  Prnka  Prize  (2012)     S.  Veeranarayanan,  A.C.  Poulose,  M.S.  Mohamed,  Y.  Nagaoka,  S.  Kashiwada,  Y.  Yoshida,  T.  Maekawa  and  D.S.  

Kumar,  Nanoformulation  facilitated  disruption  of  vasculogenesis:  Approach  towards  neo-­‐angiogenic  treatment,  Nanocon  2012,  C13  (2012),  Brno,  Czech  Republic.  

Highlighted  papers    ✓  ACS  Editors’  Choice,  American  Chemical  Society  (2014)     A.  Baliyan,  Y.  Nakajima,  T.  Fukuda,  T.  Uchida,  T.  Hanajiri  and  T.  Maekawa,  Synthesis  of  an  ultradense  forest  of  

vertically   aligned   triple-­‐walled   carbon   nanotubes   of   uniform   diameter   and   length   using   hollow   catalytic  nanoparticles,  J.  Am.  Chem.  Soc.  136,  1047-­‐1053  (2014).  

  DOI:  10.1021/ja410794p  ✓  Spotlights  on  Recent  JACS  Publications,  American  Chemical  Society  (2014).  

A.   Baliyan,   Y.  Nakajima,   T.   Fukuda,   T.  Uchida,   T.   Hanajiri   and   T.  Maekawa,  Hollow   Spheres   Lend  Control   to  Carbon  Nanotube  Growth,  J.  Am.  Chem.  Soc.  136,  1157  (2014).  

  DOI:  10.1021/ja500664b  ✓ Institute  of  Physics  (2012)     S.   Veeranarayanan,   A.C.   Poulose,   S.   Mohamed,   A.   Aravind,   Y.   Nagaoka,   Y.   Yoshida,   T.   Maekawa   and   D.S.  

Kumar,  FITC  labeled  silica  nanoparticles  as  efficient  cell  tags:  Uptake  and  photostability  study  in  endothelial  cells,  J.  Fluoresc.  22,  537–548  (2012).  

  DOI:  10.1007/s10895-­‐011-­‐0991-­‐3  

                                                       

Graduate  School  of  Interdisciplinary  New  Science  Education  and  Student  Affairs  Section,  Kawagoe  Campus,  Toyo  University  

2100,  Kujirai,  Kawagoe,  Saitama  350-­‐8585,  Japan  Tel:  +81-­‐49-­‐239-­‐1313,  Fax:  +81-­‐49-­‐231-­‐5117,  E-­‐mail:  [email protected]  URL:  http://www.toyo.ac.jp/site/english-­‐glns/  

Bio-­‐Nano  Electronics  Research  Centre,  Toyo  University  Research  Promotion  Section  

2100,  Kujirai,  Kawagoe,  Saitama  350-­‐8585,  Japan  Tel:  +81-­‐49-­‐239-­‐1375,  Fax:  +81-­‐49-­‐234-­‐2502,  E-­‐mail:  [email protected]  URL:  http://www.toyo.ac.jp/site/bionano/  

Enquiries  concerning  the  graduate  school  

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Secretariat  of  the  Bio-­‐Nano  Electronics  Research  Centre,  Toyo  University  

Secretariat  of  the  Graduate  School  of  Interdisciplinary  New  Science,  Toyo  University  

Akiko Tanaka Mikiko Koizumi

Natsue Takahashi

Yuko Tsuburaya Katsumi Funato

Minako Hardy

Narutoshi Fukushima