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![Page 1: NEW FROM GARLAND SCIENCE · Paulo Almeida Concepts in Biochemistry Proteins NEW FROM GARLAND SCIENCE 711 Third Avenue New York, NY 10017 Praise from Reviewers “This is the textbook](https://reader031.vdocuments.site/reader031/viewer/2022022409/5be5508009d3f288458b6bd7/html5/thumbnails/1.jpg)
Paulo Almeida
Concepts in Biochemistry
Proteins
NEW FROM GARLAND SCIENCE
711
Third
Ave
nue
New
Yor
k, N
Y 10
017
ww
w.g
arla
ndsc
ienc
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m
Prai
se fr
om R
evie
wer
s
“Th
is is
the
text
book
that
I ha
ve b
een
seek
ing
for m
ore
than
a
deca
de, a
dvan
ced
with
out o
bses
sive
focu
s on
ever
y de
tail
yet w
ith
a pr
oper
ly ri
goro
us a
nd th
ough
tful a
ttenti
on to
nec
essa
ry d
etai
l (a
nd e
spec
ially
so in
fram
ing
the
deriv
ation
s).”
Anne
Hin
derli
ter,
Uni
vers
ity o
f Min
neso
ta, D
ulut
h, U
SA
“[P
rote
ins:
Con
cept
s in
Bioc
hem
istry
] is a
con
cise
, foc
used
boo
k th
at c
over
s the
cor
e co
ncep
ts im
port
ant t
o pr
otei
n st
ruct
ure
and
func
tion.
I p
artic
ular
ly li
ke th
e st
rong
focu
s on
teac
hing
the
impo
rtan
ce a
nd w
ides
prea
d ap
plic
abili
ty o
f the
par
tition
func
tion.
”An
drew
Her
r, U
nive
rsity
of C
inci
nnati
Col
lege
of M
edic
ine,
USA
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994
AlmeidaBrochure_Draft3.indd 1 04/02/2016 11:11:49
![Page 2: NEW FROM GARLAND SCIENCE · Paulo Almeida Concepts in Biochemistry Proteins NEW FROM GARLAND SCIENCE 711 Third Avenue New York, NY 10017 Praise from Reviewers “This is the textbook](https://reader031.vdocuments.site/reader031/viewer/2022022409/5be5508009d3f288458b6bd7/html5/thumbnails/2.jpg)
Almeida 2-79
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Long connection
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(A)
(B) (C)
Figure 2.79 Drawing the Greek key topology of a simple β-barrel.
CONTENTS
To download a detailed table of contents and chapter sample, please visit:
Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in macromolecular structures determine protein function. Intended for a one-semester course in biochemistry or biophysical chemistry with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles.
Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first year graduate students, and practitioners in chemistry, biochemistry, biology, and biophysics.
Almeida 6-07
Figure 6.7 Structure α-TrpS with its bound substrate, IGP, shown in black (PDB 1QOQ).
Paulo AlmeidaUniversity of North Carolina Wilmington, USA
k ≈ ku
k ≈ kf
In kfwater
In ku
In k
/s–1
water
6
4
2
0
–2
–4
–6
–8
0 2 4 6 8[GuHCl] (M)
Almeida 5-34
Figure 5.34 Chevron plot of k (k = kf + ku) as a function of denaturant concentration (GuHCl).
March 2016 • Paperback • 8-1/2 x 11 432 pages • 346 illustrations978-0-8153-4502-2 • $80.00
FEATURES• Focuses on the interdisciplinary aspect of protein biophysical chemistry,
offering a quantitative description of proteins that integrates concepts from organic chemistry, physical chemistry, and biology.
• Written in consideration of the requirements for an ACS-certified BS degree in chemistry, the text meets the recommendations of the American Chemical Society, National Research Council, and National Science Foundation to feature more biochemistry and quantitative study in the life sciences.
• Each chapter ends with problem sets, with a complete solutions manual available to instructors, and key references for further reading.
www.garlandscience.com/product/isbn/9780815345022
• Artwork available in PowerPoint® and JPEG formats.• Solutions to end-of-chapter problem sets.
INSTRUCTOR RESOURCES
EXAMINATION COPIESTo apply for an examination copy for courseadoption consideration, please visit ourwebsite, garlandscience.com, or write to usat [email protected] with the followinginformation:
• Your full name, address, telephonenumber and e-mail address• Course name and number• Semesters offered• Course level• Textbook currently adopted• Number of students
Examination copies are sent at our discretion.
PLEASE SEND YOUR REQUESTS TO:Garland Science, Taylor & Francis LLC2440 Whitney Avenue Suite 214Hamden, CT 06518-1432Fax: 203-230-1186E-mail: [email protected]
Paulo Almeida is a Professor in the Department of Chemistry and Biochemistry at the University of North Carolina Wilmington. His research seeks to understand the mechanism of antimicrobial, cytolytic peptides, and cell-penetrating peptides, as well as study domain formation in lipid membranes in terms of the molecular interactions between lipids, and how they are influenced by proteins and peptides bound or incorporated into the membrane.
ABOUT THE AUTHOR
1. Statistical Thermodynamics of Biological Molecules
2. Protein Structure3. Evolution of Protein Sequence
and Structure4. Protein Stability5. Protein Folding6. Binding, Allostery, and
Cooperativity
7. Enzyme KineticsAppendix A. Calculation of the Excess Heat Capacity Curve of Protein Thermal DenaturationAppendix B. Calculation of the Average Helicity from the Partition FunctionAppendix C. Solution of Rate Equations for Two-State System
AlmeidaBrochure_Draft3.indd 2 04/02/2016 11:12:20