new features empower 3 feature release 2 - bdcint.com.do€¦ · · 2016-11-15new features...
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Empower 3 Feature Release 2New Features
©2016 Waters Corporation 1
Mr. Jose Wilson CastroLatin America Informatics Director
– Branding Refresh
– Technology updates
– Feature Updates
o ICH Impurity Processing
o Toolkit
o LDAP Enhancements
o Method Validation Manager
Agenda : Empower 3 FR2
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o Method Validation Manager
o Enhance Data Review
o QuickStart
o Usability enhancements
o Empower Analytics
o Empower Mobile
o Sample Weight Importer
o Qualification Updates
– Questions
What Sets Empower 3 Apart?
Adaptable ‘switch-on’ approach:
� Compliance
� System Suitability
� GPC & SEC
� Dissolution
� Chemical Structures
� Multi Vendor LC Control
� Multi Vendor GC Control
� Photodiode Array
� MS
� ACQUITY H Class
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� Chemical Structures
� Toolkit
� ApexTrack Integration
� Custom Calculations
� Custom Reporting
� Sample Weight Importer
� Empower Mobile
� Business Analytics
� ACQUITY H Class
� Waters SFC
� Beckman CE Control
� Enterprise Data Manager
� Method Validation Manager
� Fusion Method Development
� Waters Data Converter 2
Branding Refresh
©2016 Waters Corporation 4
� Icons
� Backgrounds
� UI Interface
� Installation Screens
Conceptual Empower 3 Pro Interface
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Proposed Empower 3 FR2 Architecture
� Technology:
– Oracle 11g(11.2.0.2 Patch set 15) R2 Database (64-bit) patch set 17
– Windows 2008 R2 Server Standard or Enterprise (64-bit)
– Windows 7 Professional & Enterprise Operating System (64-bit)
– Windows XP Operating System (32-bit) (clients and LAC/Es)
– Citrix XenApp Server 6.0 /6.5/6.8 running on Windows Server 2008 R2
Standard or Enterprise, 64-bit
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Standard or Enterprise, 64-bit
– VMWARE vSphere 5.0*
– Red Hat Linux Enterprise 6.2
� Provide a New type of group peak, Impurity Group, used to calculate Total Impurities and other user defined impurity summaries.
� Total Impurities (automatically created group peak).
� Unidentified Impurity (default impurity component type).
� Maximum Impurity (new Boolean peak field).
� PCS 42069 – Add the ability to set an acceptance criteria of ‘no impurity peak found’.
ICH Impurity Processing
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found’.
� the user can select whether the total impurities determined should be the sum of Amount, Concentration or Corrected Area % or peak custom field
� PCS 41002 – Sum total of degradation products
� The user can specify which component types should be summed (some impurities will be known and hence will use a user-defined component type, other impurities could be quantitated by default and hence be automatically defined as Unnamed Impurities)
ICH Impurity Processing
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Usability enhancements-Review
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� System suitability settings should be included in the "new processing method"
wizard
Enhanced Data ReviewConceptual New Result Audit Viewer
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� New application which will be
launched from Configuration
Manager
� Available for Personal,
Workgroup, Enterprise Users
� Privileged to Run and edit admin
section.
Empower 3Basic Business Analytics
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section.
� Ability to export
Empower 3Basic Business Analytics
� Display General Environment status of logged inusers including:
– The number Chromatographic Systems both Online and Offline
– The number of Empower Raw Data Servers, Citrix Servers, Clients, LAC/E32
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Servers, Citrix Servers, Clients, LAC/E32
– The number of Projects including Normal, Locked, Process Only, Read Only, Validation Template (?), Validation Working (?) and Total
– The User Status including the number of Active, Disabled and Removed as well as the number of Groups.
Empower 3Basic Business Analytics
� System Usage
– Total number of Injections by system
– Total number of Injections by system by month
Total number of Sample Sets by system
– Total number of Sample Sets by system by month
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Empower 3Basic Business Analytics
� Project Usage
– Total number of Injections by project
– Total number of Results by project
– Total number of Results by project by month
– Total number of Sample Sets by project
– Total number of Sample Sets by project by month
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– Total number of Sample Sets by project by month
� Message Center
– Message Center Overview
– Which systems are causing which
errors
– Which users are causing which
errors
Empower 3Basic Business Analytics
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Empower 3Basic Business Analytics
� User Analysis: There will be a place to enable or disable this
requirement based on a customer’s/country requirements.
– Total number of Injections by user
– Total number of Results by user
– Total number of Results by user by month
– Total number of Sample Sets by user
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– Total number of Sample Sets by user by month
� Methods Analysis
– Manual integration analysis – customers want this to be manual
integration tracking- Amount of manual integration that is
occurring per project and per user
– Amount of reprocessing that is occurring per project and per user.
UPLC PotentialUPLC Potential
� Top 5 HPLC to UPLC Potential
Empower 3Basic Business Analytics
� Top 5 Projects with UPLC Potential
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Empower 3 Mobile
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Empower 3 Mobile
� Waters Empower Mobile provides mobile access (via phone and tablet) to a subset of core Empower functionality.
� Functionality will be targeted for specific users, tasks and workflows
Instrument
monitoring
User / group
administrationWorkflow and
report signoff
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Pricing
� Empower Mobile will be free
– It will be an Empower option that can be installed
– It will be installed on top of an Empower client.
� Empower Mobile will only be
– installed on Empower 3 FR2
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– installed on Empower 3 FR2
– Available on Empower Client -> Server
� Users of Empower Mobile must be Empower users
– Same credentials, permissions and audit trails
The Technology
� Empower mobile is a HTML 5 based application
– Its runs inside the browser of your mobile device
– It is not installed on the mobile devices
o Web shortcuts look similar to apps
� HTML means we support browsers not devices
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� HTML means we support browsers not devices
– We will test the default browsers using key devices
� We do not IQ the mobile devices, only the server
– The server IQ can (optionally) be run following Empower mobile
server install
Architecture
IIS
Empower Mobile
Empower Client
VPN / Inside Firewall
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Empower Server
Fast
Connection
General Look and Feel
Back button
Title [Details]
Top level navigation menu• Systems• Results• Administration
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Refresh button
‘Overflow’ menu
ConfigurationHelp CommunitySign out
Current information or records
Top
Empower Sample Weight Importer (SWI)
Overview
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Solution Overview
� Starts from inside Empower, no additional login required.
Import weights from balances directly into Empower
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� Interacts with an Empower Sample Set Method
– Map weights to sample and component fields.
� Import weights to existing and running sample set methods
� Keeps a complete audit trail of all weights acquired for FAT
projects
Overview of Traditional Approach
� Traditional manual process
– Error Prone
o Easy to make Transcription Errors
o Possible to lose weights
– Traceability
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– Traceability
o Additional meta data may be lost
• Balance, date time, analyst
o No formal audit trail
o The manual process is open to manipulation
– Speed
o Writing and manually entering the weights can be a time
consuming process.
SWI High Level Workflow
� User logs into Empower
– Open Empower Run Samples / Project Window
– Select ‘Sample Weight Importer’ from custom menu
� Empower Sample Weight Importer starts
– Select balance from dropdown list
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– Select balance from dropdown list
– Select Empower sample set method
– Acquires weights and maps to samples/components
– Save the changes to the sample set method.
Mapping weights to a sample set method
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Modifying a running sample set method
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Modifying a running sample set method
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Client PC
Basic Solution Architecture
Direct Cable Connection
Ethernet Conversion(if required by balance)
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Empower
Sample Weight Importer
Empower Toolkit
SDS
Advanced Solution Architecture
Empower Network
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Ethernet Conversion(if required by balance)
Tibbo Device to connecting a balance to network
http://tibbo.com/soi/tdst.html
Example Custom field configuration
Required CustomField
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The Error for a missing customfield
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Designed for the EnterpriseDesigned for the Enterprise
Waters License Activation Center – Web
Used to activate and export licenses selected from order number
User provides contact information
User selects desired software serial numbers
License activation file is
created for download
User executes License Wizard
Software Licensing
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User executes License Wizard
to activate license on computer
Splitable user licenses
Multi database user license
Lower Total Cost of Ownership
Rapid Deployment
Silent push installs for E3 and ICS
Virtualization with VMWare
Thin Client Computing with Citrix
Designed for the Enterprise
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High Availability
Maximize uptime with Oracle RAC & Data Guard
Virtualization with VMWare
Thin Client Computing with Citrix
Enhanced WAN Compatibility
Improved software performance
Technology:
Oracle 11G R2 Database (64 bit)
Windows 2008 R2 Server Enterprise (64-bit)
Windows 7 Professional Operating System (64-bit)
Windows XP Operating System (32-bit) (clients and LAC/Es)
Citrix XenApp Server 6.0 running on Windows Server 2008
Empower 3 Architecture
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Citrix XenApp Server 6.0 running on Windows Server 2008
R2 Enterprise (64-bit)
Web based electronic licensing
Push installations
Empower 3 Client software
Instrument control software
Common CDS Platform
Europe USA
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AsiaLatin
America
Designed for the Enterprise
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Personal Workgroup Enterprise
Client-Server Environment
DatabaseServer
Raw DataServer
EmpowerClient
EmpowerClient
EmpowerClient
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ChromatographicSystems
AcquisitionServer
Citrix Environment
DatabaseServer
Raw DataServer
CitrixServer
CitrixServer
CitrixServer
Citrix Client
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ChromatographicSystems
AcquisitionServer
Oracle Real Application Clusters (RAC)
Server 1 Server 2 Server 3 Server N
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CPUCPU CPUCPU CPUCPU CPUCPU CPUCPU CPUCPU CPUCPU CPUCPU…
Mirrored Sites
SYNC/ASYNC
Primary SitePrimary Site Active Standby SiteActive Standby Site
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Broker
PrimaryDatabase
Physical or Logical Standby Database
Virtualization
� Rapid deployment
� Disaster recovery
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� Disaster recovery
� Validation benefit
� High availability
� Server consolidation
� Scalability
Authentication setting on User Account tab
sets Local or LDAP Authentication
Disables:
Enforce Unique User Passwords
Password Expiration
Enterprise Authentication Using Active Directory (LDAP)
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Limit # of Entry Attempts
Minimum Password Length
Enables LDAP Domain Manager
Allows you to define multiple
Active Directory Domains for
authentication
Questions
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