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    RUTGERS UNIVERSITY NEW BRUNSWIK UNIVERSITY OF SIENA

    RUTGERS-SIENA WORKSHOP, JUNE 10-11, 2010 -MARCH 21, 2011

    Neuroscience and Philosophy of Mind:the Debate on Mirror Neurons, Towards a ReductiveTheory of the Mirror System

    Nicola Simonetti

    PhD student in Cognitive ScienceUniversity of Siena

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    Abstract: First Part

    My talk is divided into three Parts.

    In the first Part I take into consideration the history of the mirrorneurons discovery from the staff of neurologists led by the Parmateam of Rizzolatti, Iacoboni, Gallese, etc. in the 90s (the

    announcement of the discovery dates back to 1996 on the AnnualReview of Neuroscience) and its fundamental interpretations,making use of the book of Giacomo Rizzolatti & Corrado Sinigaglia,Mirrors in the Brain. How Our Minds Share Actions and Emotions,2008 Oxford University Press, from the original one in Italianpublished by Raffaello Cortina Editor, Milan 2006.

    These fundamental interpretations are:

    1) motor and cognitive processes are not separated but very tiedbecause they are activated by some common groups of bimodalneurons which fire both when we act and observe an action (neural

    embodied simulation);

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    2) mirror neurons system would permit an immediate understandingof the intentions in the actions of other individuals (affordance

    understanding);

    3) our imitative and communicative capacity through a gesture andverbal language would be the result of an evolutionary process inwhich mirror neurons system had and has a crucial role;

    4) the immediate (not cognitive) understanding of the basicemotions of others (such as disgust, fear, happiness, etc.), alreadywell observed by C. Darwin in animals, would arise from our mirrorneurons system and would be the necessary prerequisite for thatempathic behaviour which underlies much of our inter-relationships.

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    Abstract: Second Part

    In the Second Part I take into consideration the debate on mirrorneurons that has opened from their discovery in the 90s andthat is particularly fruitful and interesting in these last years.

    In particular I want to shed light and analyze some significantstatements and reflections on the explanatory role of mirror

    neurons by the protagonists of the current debate:

    neuroscientists, cognitive scientists, psychologists andphilosophers of mind, namely G. Rizzolatti, V. Gallese,A. Caramazza, A. Goldman, P. Jacob, etc.

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    In the third part I try to clarify the theoretical concordance which I

    find between this discovery and a reductive theory of mind, notablythe supervenience reductive theory of mind claimed byJaegwon Kim (1993; 1998; 2005).

    Indeed, it seems to me that the way in which the so-called mirrorsystem works is theoretically compatible with some crucialconcepts and principles in the metaphysics of mind by Kim.

    Notably, they are:

    1) the concept of reductive psychophysical supervenience,

    according to which a mental property is realized by a species-specific physical/neural property, making use of a functional modelof reduction;

    2) the pre-emption of a physical cause on a mental cause and theredundancy and unintelligibility of mental causation;

    Abstract: Third Part

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    3) the principle of physical causal closure, according to whichthere are causes in a genuine sense only in the physicaldomain;

    4) the multi-layered metaphysical model of the world, whichdistinguishes between ontological levels (micro/macroproperties) and theoretical/conceptual orders (physical,mental, social, etc.).

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    First PartA Short History of the Discovery

    In the '80s and '90s the group of researchers at the

    University of Parma headed by Giacomo Rizzolatti

    was devoted to the study of the premotor cortex.

    They had placed electrodes in the inferior frontalcortex of a macaque monkey to study the specialized

    neurons in the control of hand movements, such as

    collecting or handling objects.

    During each experiment it was recorded the behaviourof individual neurons in the monkey brain while it

    allowed the macaque to access bits of food, in order to

    measure the neural response to specific movements.

    Like many other important discoveries, that of mirror

    neurons was due to chance.

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    The anecdotal reports that while one investigator took a banana in afruit basket prepared for the experiments,some neurons in the monkey, which waswatching the scene, had reacted. How couldit happen if the monkey had not moved?How could it happen if until then we thoughtthat these neurons are activated only formotor function?

    At first, investigators thought it was a defectin the measures or a failure in theinstrumentation, but everything turned outokay and the reactions were repeated assoon as it repeated the action of grasping.

    Since then, this work has been published,with the update on the discovery of mirrorneurons located in both the inferior frontalparietal regions of the brain and confirmed.

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    The Crucial Experiment

    In 1995, the Parma group of Rizzolatti demonstrated for the first time the

    existence in humans of a system similar to that found in monkeys.Using Transcranial Magnetic Stimulation (TMS), they found that thehuman motorcortex is facilitated by the observation of human actionsand movements of others.

    More recently, other evidences obtained by functional Magnetic

    Resonance Imaging (fMRI), TMS, ElectroEncephaloGraphy (EEG) andbehavioural tests have confirmed that similar systems existing in thehuman brain are highly developed. The regions which respond to theaction/observation have been precisely identified.

    Given the genetic similarity between primates (includinghumans), it is not surprising that these brain regions areClosely similar in them.

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    Finally, at the beginning of April 2010, Marco Iacoboni, a neuroscientistof the University of California at Los Angeles gave the important newthat the problem of proving in a direct way the existence of such a

    mirror neurons system in humans (because it is considered unethical toimplant electrodes in the brain of people for these research purposes),has been overcome, thanks to twenty-one patients treated for epilepsy.Some electrodes have been planted in their brain for medical purposes.

    During their hospitalization, the researchers told them to perform certain

    actions, such as grasping objects, or to observe facial expressions.

    According to the theory of mirror neuronssystem, mirror neurons fired both for actionand observation, and their excitement wasdirectly recorded by the electrodes.

    Among the 1177 neurons under observationa significant portion responds to both stimuli(action and observation of grasping and facialemotions) in the supplementary motor area ofthe medial frontal lobe (SMA) and in the medialtemporal lobe, specifically in the hippocampus

    arahi ocam al and the entorhinal cortex.

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    Since these new areas of the cortex perform different functions(vision, movement, memory) Iacoboni thinks that this discoverysuggest us the idea that mirror neurons provide a very rich andcomplex system of pre-logic reproduction and interpretation ofactions and emotions of others.

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    Literature on the Discovery and Its Implications

    One of the richest and most exciting books in reportingexperiments and implications arising from this importantdiscovery is Mirrors in the Brain. How Our Minds ShareActions And Emotions, 2008, Oxford University Press,from the original one in Italian by G. Rizzolatti & C.Sinigaglia, Raffaello Cortina Editor, Milan 2006.

    The central argument around which the seven chaptersof the book are articulated is that the brain that acts isalso and above all a brain that understands (Ib., p. 3).

    The meaning and scope of this statement lie in the heart

    of the neural mechanism identified by theneurophysiologists at the University of Parma headed byRizzolatti.

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    these researchers discovered in the pre-motor cortex of monkeys and

    later also in the human one the existence of two groups of neurons

    which are both active during the implementation of actions related toobjects: they are simple and familiar gestures like grabbing something

    with your hand or bringing food to your mouth.

    The surprising thing is that these two

    groups of pre-motor neurons are also

    activated in the absence of any

    enforcement action during purely

    observational explicit tasks: the first

    group of neurons respond to the vision

    of the object to which the action could be

    directed, while those of the second group

    respond to the observation of another

    individual who performs the same action.

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    Following the authors, we may take the example of the coffee cup: the

    pre-motor neurons are activated while you grasp the handle, but for

    some of them activation is triggered even by the simple observation of

    the cup resting on the table, for others also by the observation of our

    neighbour who grabs the cup to drink his coffee.

    Therefore we have in both cases bimodal neurons, that activate both

    for motor and perceptual processes.

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    The neurons of the first group were called canonical neuronsbecause since the 30s it had suggested the involvement of the pre-motor areas in the processing of visual information about an object inthe motor acts required to interact with it; those of the second groupwere called mirror neurons because they cause a mirror reaction inthe neural system of the observer, in which ittakes place a simulation of the observedaction.

    In the light of this mechanism of neuralembodied simulation, it could be reinterpretedthe role played by the motor system within thewhole cognitive system, because the first wasusually connected only with the planning andexecution of actions.

    On the contrary, it seems that bimodal neuronsfound in pre-motor cortex are stronglyimplicated in high-level cognitive processes,particularly in the perceptual recognition ofobjects and actions, and in the understanding

    of their meaning.

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    This new way of seeing and explaining the motor system, which comesto be also implied in perceptual recognition of objects and actions,and in the understanding of their meaning, undermines the rigid

    boundary between the perceptive cognitive processes and the motorones. This rigid boundary between motor and cognitive processes hasfor years characterized the interpretation of the architecture of thebrain.

    On the contrary, it seems that perception,

    understanding and action are grouped togetherinto a unified mechanism, according to whichthe brain that acts is also and above all a brainthat understands (Ib., p. 3).

    Brain understanding regarding objects isrelated to their functional significance oraffordance. Canonical neurons allow an immediate understanding ofthe possible interactions that some objects have for a perceivingsubject (in the case of the handle of a coffee cup, the possibility to begrasped).

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    With regard to the actions the understanding is related to the purposebehind them. Instead mirror neurons enable an immediateunderstanding of the intentions of other individuals (e.g. the intention

    of a man to bring the cup to his mouth to drink the coffee), makingpossible a prediction of their future behaviour.

    There are two experiments in Rizzolatti & Sinigaglias book which areconsidered very important to define the role of mirror neurons in ourunderstanding of the purpose underlying the actions. The former has

    revealed the existence of a mechanism not only in motor and visualmode, but also in auditory mode.

    Indeed, when the monkey is indarkness and listens to the noiseproduced by an action as breaking a

    nut, the same neuron fires when theanimal breaks the nut, when it seessomeone breaking a nut, and when ithears the sound of someone whobreaks it.

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    The interpretation of this experiment is that, whatever the mode, thesame neuron fires to encode the breaking that coincides with the aim,with the intention of the action.

    The second experiment has allowed to discriminate between a gestureof grabbing aimed to bring the food to the mouth or put it in a container.during the execution of that precise action (grasping), mirror neuronsfired in different ways depending on the ultimate goal of action, that is ifthe intention was to bring food to the mouth or to move it into the

    container.

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    Some results obtained with humans by an experiment with fMRI seemto go in the same direction. It was noted a particularly significantactivation of the mirror system in experimental subjects during the

    observation of actions which were not pure, but precisely included inthe context, from which one could clearly infer the intention that wasimplied.

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    All these experiments would allow us to state that the mirror neuronssystem is able to encode not only the act, but also the intention withwhich it is made.

    According with the paradigm of the embodied cognition (endorsed bymany philosophers and neurobiologists, namely A. Clark, A. Damasio,etc.), the intentions of others can be understood without any reflectiveconceptual or linguistic mediation. It would be nothing but a pragmaticunderstanding based solely on the motor knowledge on which it

    depends our own capacity to act.

    Two other important functions assigned to the mirror system aredescribed in Rizzolatti & Sinigaglias book, asbasilar capacities which would make the verbaland non verbal language possible.

    They are:1- an imitative function intended as the ability toreplicate gestures already belonging to our ownmotor repertoire;

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    2- the capacity of learning new motor patterns by imitation.

    It is a common function that would also outline a possible scenario for

    the origin of human language related to the evolution of the mirror

    system, which could be interpreted in this sense as an instrument ofintegration between gestures and sounds to foster a more precise

    understanding of social behaviours.

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    Dulcis in fundo, the last chapter of the book, entitled Sharingemotions, is dedicated to the sharing of emotions.

    The central thesis is that the recognition of the emotions of others isbased on a set of different neural circuits which share the mirrorproperties already seen in the case of action understanding. It waspossible to study experimentally some primary emotions such aspain and disgust, and the results clearly show that observing in theother an expression of sorrow or disgust activates the same neural

    substrate underlying the perception in first person of the same kindof emotion, as if it were a sort of involuntary perceptual and motorimitation.

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    Far from being confined to the functioning of certain nerve cells, themirror properties would pervade the entire system of the brain: the same

    logic that allows us to pair execution and action understanding in asingle neural mechanism, allow us also to describe the emotionalsharing and perhaps even the arising of the phenomenon ofconsciousness.

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    Second Part

    After the discovery of mirror neurons in the 90s by the group ofresearchers at the University of Parma, headed by G. Rizzolatti andcomposed by L. Fadiga, L. Fogassi, V. Gallese and G. di Pellegrino,it has opened, above all in the last years, a fruitful and interetingdebate on the explanatory role of mirror neurons for cognitivefunctions.

    In particular I want to shed light on some significant statements andreflections about the explanatory role of mirror neurons through someprotagonist of the current debate:

    neuroscientists, cognitive scientists, psychologists and philosophersof mind, namely G. Rizzolatti, V. Gallese, A. Caramazza, A. Goldman,P. Jacob, etc.

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    We proved that we have a basic neuralmechanism that allows us to enter intorelationships with others: in addition to rational

    and intellectual knowledge, there is an intimateand direct knowledge of what you are doing.If a Martian interacts with us with strangecontractions, we wouldnt understand what it isdoing, because we do not recognizeits gestures in an experiential map.Experiments done with fMRI showed that ifsomeone makes some human actionsmirror neurons activate, while it doesnt happenwhen a dog barks, for example, becausethe experience of the bark is not a part of

    our biological and cultural heritage.The keyword is experience, and experiencechanges our biological heritage.

    (Giacomo Rizzolatti, Full Professor of Human Physiology,Director of the Department at the University of Parma)

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    The discovery of motor resonance mechanismof mirror neurons has shown that the motor

    system, far from being a mere musclescontroller and a simple executor of commandscoded elsewhere, is able to perform cognitivefunctions that for a long time have beenerroneously considered prerogative ofpsychological processes and neural

    mechanisms of a purely associative kind...Surely mirror neurons bother who look atneuroscience as a simple method of tracking and validation ofmental mechanisms deemed valid a priori.

    (Vittorio Gallese, Medical neurologist,is Professor of Physiology at the University ofParma)

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    Till now we havent had any important clinical

    demonstration that mirror neurons really have

    a functional role in the action understanding

    and, even if they do, in which way they can do

    it.

    (Alfonso Caramazza, Director of the

    Laboratory of Cognitive Neuropsychology at

    Harvard University and Director of the

    International Center for Mind/Brain Science of

    the University of Trento).

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    It is important to keep several questions distinct.When do we have simulation? When do we have

    mirror neurons? When do we have social-intentional relationships? I do not argue thatconceptualization and imputation are necessaryfor the existence or activation of mirror neurons(MNs), only that they (or something similar) arenecessary for social-intentional relationships.

    If MNs themselves do not guarantee suchelements, then they dont, all by themselves,guarantee social-intentional relationships.

    (Alvin Goldman, Board of Governors Professorof Philosophy and Cognitive Science at Rutgers,The State University of New Jersey).

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    Human ability to represent psychologicalstates (beliefs, intentions, desires, emotions)

    and to attribute them to others (so-calledmindreading) goes beyond the mechanism ofmirror neurons. Consequently, also the ideathat autism stems from lack of mirror neuronsis wrong.

    (Pierre Jacob, Philosopher of Mind andCognitive Scientist, currently President of theEuropean Society of Philosophy andPsychology and Director of the Jean NicodInstitute in Paris).

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    Third PartThe theoretical concordance between mirror systemworking and the supervenience reductive theory of

    mind by Jaegwon Kim

    In the second part of my talk I try to show thetheoretical concordance of this discovery with areductive theory of mind, and particularly with thesupervenience reductive theory of mind claimed by

    J. Kim (1993; 1996; 1998; 2005).

    Indeed, it seems to me that the way in which the so-called mirror system works is theoreticallycompatible with some crucial concepts andprinciples in the metaphysics of mind by Kim.

    Notably, they are:the concept of reductive psychophysical supervenience, accordingto which a mental property is realized by a species-specificphysical/neural property, making use of a functional model ofreduction;

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    2) the pre-emption of a physical cause on a mental cause and theredundancy and unintelligibility of mental causation; 3) the principleof physical causal closure, according to which there are causes in a

    genuine sense always in the physical domain; 4) the multi-layeredmetaphysical model of the world, which distinguishes betweenontological levels (micro/macro properties) and theoretical/conceptual orders (physical, mental, social, etc.).

    1) Now, lets start with order considering these points starting from

    the concept of psychophysical supervenience, canonicallyformulated by Kim:

    [[[[Psychophysical supervenience]]]] The mental supervenes on the physical inthat any two things (objects, events, organisms, persons etc.) exactly alike inall physical properties cannot differ in respect of mental properties (Kim,

    1996, p. 10).

    We can recognize three basic principles which found the canonicalconcept of psychophysical supervenience, as it was officiallyintroduced in philosophy of mind by Davidson, in his Mental Events(1970).

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    (i) Covariance(only apparently asymmetrical) of properties: if two things orindividuals are indiscernible in relation to their base physical properties, theywill be indiscernible in relation to their mental or higher-level properties too,

    while its not necessarily worth vice versa.

    (ii) Dependence: supervenient properties depend or are determined on/bybasic-physical properties.

    (iii) Irreducibility: supervenient mental properties are not reducible in thecanonical version of supervenience- to their physical base properties (from anomological/explicative point of view).

    Leaving aside the long and complex history of this concept andstarting from the last interpretation of Kim (1998) in a reductive sense,it means that a physical base property Pis necessarily sufficient forthe supervenient mental property Mbecause supervenient propertiesdepend or are determined on/by their subvenient species-specificproperties and theres an ontological identity between them, beinginstantiated in the same time t.

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    It seems to me that these distinctive features of the concept ofpsychophysical supervenience are fully consistent in a theoreticalway with the functioning of mirror neurons and the mirror system,

    according to which perceptual and cognitive processes are realizedon the same neural circuitry of motor processes, depending on theirway of working.

    By this way, a will or an intention may be read as a motor dispositionrealized on its own neural circuitry.

    2) Hence, its clear that a genuine causal action or causation takesplace first at a physical level, in the activation of neural circuits thatrealized the motor and cognitive processes.

    In fact, as Kim himself says (1998), mental causation comes to beredundant because physical causation is necessary and sufficient.

    In the same way Kims functional model of reduction, according towhich the gene is the role played by DNA, is part of a reductiveexplanation of many behaviours that we would erroneously consider

    as totally cognitive.

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    Instead, in light of these discovery, studies and experiments, many

    cognitive behaviours seem to be much embedded and involuntary, in

    spite of appearance (as the awareness processes, e.g. decision making

    and will, namely described by B. Libet, 2004).

    Lets see the picture in which Kim (1996, p. 51) distinguishes

    supervenience from physical causation and from mental or supervenient

    causation.

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    Its first the neural state, according to supervenient causationmodel, to cause, on one side, a certain neuro-phisiological event, themuscle contraction, on which wincing supervenes, while, on the

    other, to constitute the supervenience base of pain, which causes, ona mental level, wincing.

    This model considers higher order properties as necessarilydependent or supervenient on their realizers at a physical deeperlevel, and considers mental causal processes as necessarily

    dependent or supervenient on those at a physical deeper level,which is the only genuine causal level.

    3) The reason is that physical domain is causally closed: indeedtheres no mental or non-physical cause for itself, that is without aphysical base of realization.

    Kim (1998) describes by these words his crucial principle of causalclosure: If you pick any physical event and trace out its causalancestry and posterity, that will never take you outside the physicaldomain. That is, no causal chain will ever cross the boundarybetween the physical and the non-physical. (Kim, 1998, p. 40)

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    4) Finally, I consider Kims distinction between levels (micro/macro)and orders (physical/mental), drawn in the third chapter of Mind ina Physical World, very interesting and important from a logical and

    metaphysical point of view, towards a reductive theory of mind.

    His starting point, is that mental properties or, generally speaking,second-order properties, are realized on physical/neural properties,as their base of supervenience. This realization relation should makethe multilayered structure of levels arising.

    But now, which is the relation between level hierarchy and orderhierarchy? Kim stresses the fact that both second-order propertiesand their first-order realizers are properties of the same entities andsystems (Ib., p. 82). Which means to say that order hierarchy takesplace on a same level, being first/second/n-order properties nothingbut properties of the very same object or system on a certain micro/macro level.

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    So, making use of Kims significant words, when we talk of second-order properties and their realizers, theres no movement downward, orupward, in the hierarchy of entities and their properties ordered by the

    micro-macro relation (Ib., p.91). And again, to differ order with levelseries: the series created by the second-order/realizer relation does nottrack the ordered series of micro-macro levels; it stays entirely within asingle level in the micro-macro hierarchy (Ib., p. 82).

    This distinction between order hierarchy and level hierarchy seems

    undoubtedly crucial at least to award causal efficacy to someproperties. We may observe, for example, that order-properties within asupervenient progression from first-order (physical) properties tosecond-order (mental) properties, as C/fibers exciting property and thefeeling of pain, are all properties applying to entities at a single micro-macro level with no further injection of causal powers at the higherorders.

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    On the contrary, spin, charm, and such are properties of elementaryparticles, and they have no application to atoms, molecules, andhigher objects in the micro-macro hierarchy; transparency and

    inflammability are properties of aggregates of molecules, and theyhave no place for atoms or more basic particles. (Ib., p. 83)

    In the same way consciousness and intentionality are properties ofbiological organisms, or at least of neural systems, and they have noapplication to entities which are micro in relation to them.

    If this is right, we should correctly speak of first/second/n-orderproperties within a metaphysical hierarchy of orders only for a sameobject or system, and it is about this order hierarchy we shouldimagine and recognize the relation of psychophysical supervenience.It is well known, then, that this logical and metaphysical relation of

    dependence and determination of mental properties on physicalproperties entails, according to Kim (1998), the idea of reducibility andcausal inefficacy of mentality, whose apparent causal powers would beinherited from its physical base.

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    This idea, from my point of view, clearly leads to a reductive way ofinterpreting every mental process as it has shown by mirror systemworking.

    Vice versa, micro-macro level hierarchy does not concern properties ofa same object, but different properties for different objects, dependingon their complexity in micro-macro progression.

    Within this progression you may speak of supervenience too, but only

    in a mereological sense, that is the micro-based property (as astructural property in David Armstrong) on its micro-constituents,such as, for example, a water molecule mereologically supervenes ontwo hydrogen atoms and one oxygen atom.

    Following Kims arguing, H2O molecules have causal powers that nooxygen or hydrogen atoms have (Ib., p. 85). In the same way, a neuralassembly consisting of many thousands of neurons will haveproperties whose causal powers go beyond the causal powers of theproperties of its constituents neurons, or subassemblies, and humanbeings have causal powers that none of our individual organs have.

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    By this way, we might claim proper causal powers for emergent

    complex properties, such as cognitive faculties and consciousness in

    human beings, in spite of their reductive and functional explanation via

    realization.

    So, macro-properties in level hierarchy, in a different way from second-

    order properties in order hierarchy, can, and in general do, have their

    own causal powers, which go beyond the causal powers of their micro-

    constituents.

    Here it is the importance, to me, of the distinction between orders and

    levels, whose target is not only to make clear our language, but also to

    clarify which properties have proper causal powers and which ones

    have not.

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    Among the macro-properties we may include, according to Kim,

    intentionality and consciousness, awarding special causal powers to

    them, because they are located on a higher ontological level:consciousness and intentionality are properties of

    biological organisms (Kim, 1998, p. 83).

    About consciousness, intentionality and complex mental phenomena,

    the mirror neurons discovery, since it shows a close neuro-physiological link between motor processes and cognitive functions

    as perception, vision, etc, thus it confirms, in my opinion, the fact that

    our descriptive orders for a behaviour, such as intentionality, will,

    etc.. lie on the same physical level of the implementation of that

    behaviour, often even before our awareness, as it is shown by Libet(2004) experiments on consciousness and will.

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    In conclusion, the discovery of mirror neurons, as well as giving animmediate biological foundation to the concept of empathy and related

    ideas, makes us understand, in my opinion, as well observed in theForeword to Rizzolatti & Sinigaglia (2006), that

    The same rigid boundary between perceptual, cognitive and motorprocesses, ends up being largely artificial: not only perception isimmersed in the dynamics of the action, being more articulate and

    complex than previously thought, but the brain that acts is primarily abrain that understands. This is [...] a pragmatic, pre-conceptual andpre-linguistic, understanding, and yet no less important, since it restson many of our much celebrated cognitive abilities (Ib., p. 3).

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    Thank you for your attention!

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    Libet, B. (2004),Mind Time. The Temporal Factor in Consciousness, by the President andFellows of Harvard College.

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    Simonetti, N. (2003), Levels and Orders: The Multi-Layered Metaphysical Model of J.

    Kim, Book of Abstracts, European Society for Philosophy and Psychology (ESPP), Tourin,

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