neurology · walton centre for neurology and neurosurgery, liverpool a pocket-sized ready-reference...

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Acute Stroke Care A Manual from the University of Texas – Houston Stroke Team Ken Uchino Jennifer Pary and James Grotta All from University of Texas, Houston You have just encountered a possible stroke patient. You ask yourself, what should I do first? How do I know it is a stroke? Is it too late to reverse the damage? How do I do the right things in the right order? This book will help you answer these critical questions. It provides practical advice on the care of stroke patients in a range of acute settings. All types of stroke are covered. A comprehensive set of appendices contain useful reference information including dosing algorithms and stroke scales. • Provides practical advice on the emergency care of stroke patients • Tells you how to do the right things in the right order • Includes appendices of useful reference information Contents: Preface; List of abbreviations; 1. Stroke in the emergency department; 2. What to do first; 3. Ischemic stroke; 4. TPA protocol; 5. Neurological deterioration in acute ischemic stroke; 6. Ischemic stroke prevention: why we do the things we do; 7. Transient ischemic attack (TIA); 8. Intracerebral hemorrhage (ICH); 9. Subarachnoid hemorrhage (SAH); 10. Organization of stroke care; 11. Rehabilitation; Appendices 1-14. Cambridge Pocket Clinicians series 2007 178 x 108 mm 230pp 9 line diagrams 13 half-tones 15 tables 978-0-521-67494-2 Paperback £25.99 The Stroke Book Edited by Michel T. Torbey Medical College of Wisconsin, Milwaukee and Magdy H. Selim Harvard Medical School, Massachusetts A concise and practical reference to help physicians become more comfortable with decision making and management of the critically ill cerebrovascular patient. Contributors from leading stroke centers cover a wide range of common conditions such as ischemic and hemorrhagic strokes, subarachnoid hemorrhage, and aneurysms, and provide focused protocols for assessing and treating patients in the emergency room, intensive care unit, or hospital floor. The chapters are packed with algorithms and summary tables providing immediate access to key information. The CD allows users to download the text. • A hands-on approach • Helpful algorithms and tables provide quick access to key information • An accompanying CD containing downloads to PC or hand-held devices Contents: 1. EMS: first line of defense against stroke; 2. Initial assessment of patients with stroke-like symptoms; 3. Clinical stroke syndromes and localization; 4. The hunt for a stroke etiology: ischemic stroke; 5. Hemorrhagic stroke: the hunt for a stroke etiology; 6. Uncommon causes of stroke; 7. Computed tomography in acute stroke; 8. Magnetic resonance imaging in acute stroke; 9. Neurosonology in acute ischemic stroke; 10. Ischemic stroke in the first 24 hours; 11. Ischemic stroke beyond the first 24 hours; 12. Intracerebral hemorrhage; 13. Subarachnoid hemorrhage; 14. Dural and cerebral sinus thrombosis; 15. Perioperative stroke; 16. Stroke on OB/Gyn wards; 17. Stroke on pediatric wards; 18. Antithrombotic therapies; 19. Surgical and endovascular therapies ; 20. Stroke risk factors: impact and management. 2007 228 x 152 mm 344pp 61 half-tones 48 tables 978-0-521-67160-6 Paperback £25.99 Neurology CLINICAL NEUROLOGY

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Page 1: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Acute Stroke CareA Manual from the University of Texas – Houston Stroke TeamKen UchinoJennifer Paryand James GrottaAll from University of Texas, Houston

You have just encountered a possible stroke patient. You ask yourself, what should I do first? How do I know it is a stroke? Is it too late to reverse the damage? How do I do the right things in the right order? This book will help you answer these critical questions. It provides practical advice on the care of stroke patients in a range of acute settings. All types of stroke are covered. A comprehensive set of appendices contain useful reference information including dosing algorithms and stroke scales.• Providespracticaladviceontheemergency

careofstrokepatients

• Tellsyouhowtodotherightthingsintherightorder

• Includesappendicesofusefulreferenceinformation

Contents: Preface; List of abbreviations; 1. Stroke in the emergency department; 2. What to do first; 3. Ischemic stroke; 4. TPA protocol; 5. Neurological deterioration in acute ischemic stroke; 6. Ischemic stroke prevention: why we do the things we do; 7. Transient ischemic attack (TIA); 8. Intracerebral hemorrhage (ICH); 9. Subarachnoid hemorrhage (SAH); 10. Organization of stroke care; 11. Rehabilitation; Appendices 1-14.

Cambridge Pocket Clinicians series

2007 178 x 108 mm 230pp 9 line diagrams 13 half-tones 15 tables978-0-521-67494-2 Paperback £25.99

The Stroke BookEdited by Michel T. TorbeyMedical College of Wisconsin, Milwaukee

and Magdy H. SelimHarvard Medical School, Massachusetts

A concise and practical reference to help physicians become more comfortable with decision making and management of the critically ill cerebrovascular patient. Contributors from leading stroke centers cover a wide range of common conditions such as ischemic and hemorrhagic strokes, subarachnoid hemorrhage, and aneurysms, and provide focused protocols for assessing and treating patients in the emergency room, intensive care unit, or hospital floor. The chapters are packed with algorithms and summary tables providing immediate access to key information. The CD allows users to download the text.• Ahands-onapproach

• Helpfulalgorithmsandtablesprovidequickaccesstokeyinformation

• AnaccompanyingCDcontainingdownloadstoPCorhand-helddevices

Contents: 1. EMS: first line of defense against stroke; 2. Initial assessment of patients with stroke-like symptoms; 3. Clinical stroke syndromes and localization; 4. The hunt for a stroke etiology: ischemic stroke; 5. Hemorrhagic stroke: the hunt for a stroke etiology; 6. Uncommon causes of stroke; 7. Computed tomography in acute stroke; 8. Magnetic resonance imaging in acute stroke; 9. Neurosonology in acute ischemic stroke; 10. Ischemic stroke in the first 24 hours; 11. Ischemic stroke beyond the first 24 hours; 12. Intracerebral hemorrhage; 13. Subarachnoid hemorrhage; 14. Dural and cerebral sinus thrombosis; 15. Perioperative stroke; 16. Stroke on OB/Gyn wards; 17. Stroke on pediatric wards; 18. Antithrombotic therapies; 19. Surgical and endovascular therapies ; 20. Stroke risk factors: impact and management.

2007 228 x 152 mm 344pp 61 half-tones 48 tables978-0-521-67160-6 Paperback £25.99

NeurologyCLINICAL NeUroLogy

Page 2: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

The Behavioral and Cognitive Neurology of StrokeEdited by Olivier GodefroyUniversité de Picardie Jules Verne, Amiens

and Julien BogousslavskyUniversité de Lausanne, Switzerland

The care of stroke patients has changed dramatically in recent years. As well as improvements in the emergency care of the condition, there have been marked advances in our understanding, management and rehabilitation of residual deficits. This book is about the care of stroke patients, focusing on behavioral and cognitive problems. It provides a comprehensive review of the field covering the diagnostic value of these conditions, in the acute and later phases, their requirements in terms of treatment and management, and the likelihood and significance of long-term disability. • Providesacomprehensivereviewofthe

disordersobservedinstroke

• Combinesinformationfromneuropsychologicalandstrokestudies

• Describestheassessmentandcareofthesedisorders

Contents: Introduction; 1. Evaluation of cognitive and behavioral disorders in the stroke unit; Motor and Gestural Disorders: 2. Abnormal movement and motor behavior; 3. Gestural apraxia, Aphasia and arthric disorders; 4. Aphasia in stroke; 5. Acute vascular aphasia; 6. Dysarthria; 7. Alexia and agraphia; 8. Acalculia and Gerstmann’s Syndrome; Hemineglect, Anton-Babinski and Right Hemisphere Syndromes: 9. Hemineglect; 10. Anosognosia and denial after right hemisphere stroke; 11. Asomatognosia; 12. Disorders of visuoconstructive ability; 13. Topographical disorientation; Agnosia and Balint syndrome 14. Cortical blindness, 15. Balint’s Syndrome; 16. Prosopagnosia; 17. Object and colour agnosia; 18. Auditory disorders related to strokes; Executive and Memory Disorders: 19. Dysexecutive syndromes; 20. Disorders of episodic memory; 21. Working memory dysfunctions in stroke patients; Behavioral and Mood Disorders: 22. Akinetic mutism and related disorders; 23. Alterations of level of consciousness related to stroke; 24. Delirium and confusional state in stroke patients.

2007 247 x 174 mm 664pp 93 line diagrams 8 colour plates 120 tables978-0-521-84261-7 Hardback £85.00

Case Studies in StrokeCommon and Uncommon PresentationsMichael G. HennericiUniversität Mannheim, Germany

Michael DaffertshoferUniversität Mannheim, Germany

Louis R. CaplanHarvard University, Massachusetts

and Kristina SzaboUniversität Mannheim, Germany

This selection of 60 stroke cases will inform and challenge clinicians at all stages in their careers. Including both common and unusual cases, the aim is to reinforce diagnostic skills through careful analysis of individual presenting patterns, and to guide treatment decisions. Each case is illustrated, and includes history, examination and diagnosis with a discussion of the clinical issues in which the main teaching points are emphasized. Selected references, frequently including the first description, are provided at the conclusion of each case.• Casesselectedbyleadingteachersand

clinicians

• Illustratedwithneuroimagingfindings

• Discussionofmainteachingpointsofeachcase

Contents: Part I. Common Cases of Stroke; Part II. Uncommon Cases of Stroke.

2006 247 x 174 mm 290pp 8 line diagrams 50 half-tones978-0-521-67367-9 Paperback £35.00

The A-Z of Neurological PracticeA guide to Clinical NeurologyRoger A. BarkerUniversity of Cambridge

Neil ScoldingInstitute of Clinical Neurosciences, Bristol

Dominic RoweUniversity of Sydney

and Andrew J. LarnerWalton Centre for Neurology and Neurosurgery, Liverpool

A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries, each one describing, in a readable and accessible style, an aspect of neurology. This ranges from providing overviews of major groups of diseases (e.g. the dementias) to more detailed coverage of specific disease categories (e.g. Alzheimer’s disease). This will become an essential resource for all those undertaking training in neurology, as well as providing a reference source for generalists looking for a readable synopsis of neurological conditions.• Succinctandstructuredcoverageof

neurology

• Organisedforeaseofaccessandnavigation

‘Thisbookissmallenoughtobethrownintoabagorbriefcaseonthewaytotheclinicandyetitsscopeisbroad.Itiswellwritten…Itisnosmallfeattocoverthebreadthofneurologicalconditionsinsuchasmallform-factor.…itisideallyplacedasaquickandhandyreferenceguide.Itmustberecommended.’

acta neurochirurgica

2004 186 x 123 mm 938pp978-0-521-62960-7 Paperback £25.99

Page 3: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Neurodegenerative DiseasesNeurobiology, Pathogenesis and TherapeuticsM. Flint BealCornell University, New York

Anthony E. LangUniversity of Toronto

and Albert C. LudolphUniversität Ulm, Germany

This major reference reviews the rapidly advancing knowledge of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.• Largestandmostcomprehensivereferencetexton

neurodegenerativedisease

• Editorsandcontributorsincludetheworld’sleadingauthoritiesinternationally

• Coversbasicneuroscienceandclinicalfeatures

Contents: Part I. Basic Aspects of Neurodegeneration; Part II. Neuroimaging in Neurodegeneration; Part III. Therapeutic Approaches in Neurodegeneration; Part IV. Normal Aging; Part V. Alzheimer’s Disease; Part VI. Other Dementias; Part VII. Parkinson’s and Related Movement Disorders; Part VIII. Cerebellar Degenerations; Part IX. Motor Neuron Diseases; Part X. Other Neurodegenerative Diseases.

2005 276 x 219 mm 1008pp 45 line diagrams 57 half-tones 80 tables978-0-521-81166-8 Hardback £240.00

➤NEwLOwPrICE£125

Diseases of the Nervous SystemClinical Neuroscience and Therapeutic PrinciplesThird editionEdited by Arthur K. AsburyUniversity of Pennsylvania School of Medicine

Guy M. McKhannThe Johns Hopkins University School of Medicine

W. Ian McDonaldUniversity College London

Peter J. GoadsbyUniversity College London

and Justin C. McArthurThe Johns Hopkins University School of Medicine

The third edition of a neurology classic, this two-volume text is the most comprehensive neurology reference available. It encompasses the basic neuroscience and clinical features of the full range of neurological disorders, written by leading international experts in the field. Disease mechanisms are reviewed comprehensively, with particular relevance to the principles of therapy. Current, comprehensive and authoritative, this is the definitive reference for neurologists, neurosurgeons, neuropsychiatrists, indeed everyone with a professional or research interest in the neurosciences.

‘…aremarkableandsuccessfulefforttopresentinacomprehensiveyetconcisemanneramassiveamountofdataonneurologicaldiseases…themainvalueofthisbookforpsychiatristsorneurologistsworkingwithchildrenresidesinthesuperbcoverageofthegeneralpathophysiologicalandtherapeuticaspects.Paediatricspecialistswillfindinthisbooknewconceptsandideasaboutneurologicaldisordersthatmaybeofvalueatanyage,allowingabetterandmoreup-to-dateunderstandingofsomeoftheconditionstheyhavetodealwith.’

european child and adolescent psychiatry

Contents: Part I. Introduction and General Principles; Part II. Disorders of Higher Function; Part III. Disorders of Motor Control; Part IV. Disorders of the Special Senses; Part V. Disorders of Spine and Spinal Cord; Part VI. Disorders of Body Function; Part VII. Headache and Pain; Part VIII. Neuromuscular Disorders; Part IX. Epilepsy; Part X. Cerebrovascular Disorders; Part XI. Neoplastic Disorders; Part XII. Autoimmune Disorders; Part XIII. Disorders of Myelin; Part XIV. Infections; Part XV. Trauma and Toxic Disorders; Part XVI. Degenerative Disorders; Part XVII. Neurological Manifestations of Systemic Conditions.

2002 276 x 219 mm 2194pp 200 line diagrams 200 half-tones 25 colour plates 350 tables 50 figures978-0-521-79351-3 Hardback £360.00

Page 4: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Clinical Uses of Botulinum ToxinsEdited by Anthony B. WardUniversity Hospital of North Staffordshire

and Michael P. BarnesHunters Moor Regional Neurological Rehabilitation Centre

Botulinum toxins play a very significant role in the management of many medical conditions; from headaches to hypersalivation, and spasticity to sweating. In this book, an international team of experts outline the neurochemistry of botulinum toxins and their progress from laboratory to clinic. Following chapters summarize their clinical use in the context of other available treatments. The book will be of interest to neuroscientists and practising clinicians working in a wide range of specialities, from neurology and dermatology to pediatrics, plastic surgery and rehabilitation medicine.• AnInternationalteamofexperts

comprehensivereviewofbotulinumtoxins.

• Coversthemainindicationsfortheclinicaluseofbotulinumtoxininawiderangeofspecialitiesandcoversthebasicneurochemistryandcommercialdevelopmentofthetoxin

Contents: 1. Introduction; 2. Mechanistic basis for the therapeutic effectiveness of botulinum toxin A on over-active cholinergic nerve; 3. Botulinum toxin: from menace to medicine; 4. Botulinum toxin: primary and secondary resistance; 5. Introduction to botulinum toxin and clinical practice; 6. Cervical dystonia; 7. The use of botulinum toxin in otolaryngology; 8. Spasticity 9. Hyperhidrosis; 10. Hypersalivation; 11. Botulinum toxin type A for the prophylactic treatment of primary headache disorders; 12. Botulinum toxin in the management of back and neck pain; 13. Ophthalmological uses of botulinum toxin; 14. Bladder and bowel indications; 15. Cosmetic uses of botulinum toxin type A; 16. Other clinical neurological uses of botulinum toxin.

2007 247 x 174 mm 394pp 25 line diagrams 23 half-tones 47 tables978-0-521-83304-2 Hardback £65.00

DizzinessA Practical Approach to Diagnosis and ManagementAdolfo M. BronsteinCharing Cross Hospital, London

and Thomas LempertCharite University Hospital and Schlosspark-Klinik, Berlin

A novel approach to the diagnosis of dizziness, with chapters organized by clinical presentations. A table with differential diagnoses is given at the beginning of each chapter, including key features of each disorder. The authors’ friendly approach extends to advice on history taking, clinical examination and treatment, and each chapter ends with hints on ‘what to do if you haven’t a clue’. Common disorders are highlighted, with brief coverage of rarities, and a useful CD shows the clinical examination, positioning and exercises for vestibular rehabilitation.• Organisedtoassistdifferentialdiagnosis

• Inspiresconfidenceinadifficultclinicalarea

• CDshowshowtoexamineandpositionthepatient

• Hintson‘whattodoifyouhaven’taclue’

Contents: 1. Essential anatomy and functions of the balance system; 2. Symptoms and examination of the patient with dizziness; 3. A single episode of prolonged vertigo; 4. Recurrent vertigo and dizziness; 5. Positional vertigo; 6. Chronic dizziness and unsteadiness; 7. Dizziness and falls in the elderly; 8. Treatment of the dizzy patient.

Cambridge Clinical Guides

2007 228 x 152 mm 238pp 24 line diagrams 15 half-tones 52 tables 2 graphs 41 figures978-0-521-83791-0 PB and CD-ROM £35.00

Frontotemporal Dementia SyndromesEdited by John R. HodgesUniversity of Cambridge

In the past decade there have been enormous advances in our understanding of frontotemporal dementia and related syndromes. The impetus for these advances has come from a number of directions including genetic discoveries, new approaches to neuroimaging and improved neuropsychological understanding of the cognitive aspects of the condition. This book provides a much needed review of the current status of our knowledge of these syndromes. Frontotemporal Dementia Syndromes will be essential reading for neurologists, psychologists, and psychiatrists, as well as to basic scientists working in the area of neurodegeneration.• Providesacomprehensiveupdateofa

dynamicareaofresearchfromateamattheforefrontofthefield

• Coverstheverylatestadvancesfromthefieldsofgenetics,neuroimagingandneuropsychology

• Proposesamultidisciplinaryapproachtopatientmanagement

Contents: Preface; 1. Overview of frontotemporal dementia; 2. Epidemiology of frontotemporal dementia; 3. Clinical presentations of frontotemporal dementia; 4. Overlap syndromes; 5. The neuropsychology of frontotemporal dementia; 6. Neuroimaging and other investigative findings; 7. The histopathology of frontotemporal dementia R.; 8. Molecular neuropathology in familial and sporadic frontotemporal dementia; 9. The genetics of frontotemporal dementia; 10. Psychological interventions in frontemporal dementia.

2007 247 x 174 mm 354pp 14 line diagrams 19 half-tones 1 colour plate 22 tables978-0-521-85477-1 Hardback c. £60.00

Page 5: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

The Pseudotumor Cerebri SyndromePseudotumor Cerebri, Idiopathic Intracranial Hypertension, Benign Intracranial Hypertension and related ConditionsIan JohnstonUniversity of Sydney

Brian OwlerWestmead Hospital, Sydney

and John PickardUniversity of Cambridge

The condition known most widely as pseudotumor cerebri syndrome is of diagnostic interest and clinical importance not just to neurosurgeons, but to neurologists, ophthalmologists and headache specialists. Three clinicians with extensive experience of pseudotumor cerebri provide a comprehensive review of the condition including its history, discussion of the more contentious issues, aetiology, investigative findings and strategies, treatment and outcome, and a wide-ranging review of the clinical literature. Concluding with a chapter on experimental studies, this book points the way to a more complete understanding of this controversial condition.• Acomprehensivereviewofthesubject

givingcliniciansthebasisforarationalapproachtodiagnosisandmanagement

• Basedontheauthors’ownextensivepatientseriesandliteraturereview

• resolvesissuesofaetiologyandterminologywithaunifyinghypothesis

Contents: 1. Introduction; 2. History of the Pseudotumor cerebri concept; 3. Disease mechanism; 4. Nosology, nomenclature, and classification; 5. Aetiology; 6. Clinical Features; 7. Clinical Investigations; 8. Treatment; 9. Outcome; 10. Experimental Studies; 11. Conclusions; 12. Bibliography.

2007 247 x 174 mm 368pp 18 line diagrams 24 half-tones 30 tables 44 figures978-0-521-86919-5 Hardback £85.00

Antiepileptic DrugsCombination Therapy and InteractionsEdited by Jerzy MajkowskiFoundation of Epileptology, Warsaw

Blaise F. D. BourgeoisHarvard University, Massachusetts

Philip N. PatsalosInstitute of Neurology, London

and Richard H. MattsonYale University, Connecticut

This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations and future directions for this field of research.• Coversthebenefitsandpitfallsof

combinationtherapy

• Describesmechanismsofinteractionsaswellasclinicalsignificance

• Contributionsfromaninternationalteamofauthorsandeditors

2005 247 x 174 mm 514pp 16 line diagrams978-0-521-82219-0 Hardback £90.00

Palliative NeurologyIan MaddocksFlinders University of South Australia

Bruce BrewUniversity of New South Wales, Sydney

Heather WaddyWakefield Hospital Specialist Centre, Adelaide

and Ian WilliamsWalton Centre for Neurology & Neurosurgery

Techniques of palliative care have evolved as a reaction to discomforts such as pain in terminal cancer. Neurological disorders, including dementia, stroke, Parkinson’s disease or multiple sclerosis cause different discomforts, and they commonly persist for years. This handbook offers practical advice about how the multi-disciplinary approach to comprehensive care that developed in early models of palliative management can bring support and symptom relief to those who suffer from chronic neurological diseases. It should be read by clinicians and allied health professionals involved in the care of those with neurological disorders.

‘IfyouneedaquickandeasyintroductiontopalliativecareandanswerstosymptomcontrolquestionsthenPalliativeNeurology…isforyou…’

advances in clinical neuroscience and rehabilitation

Contents: Part I. Palliative Management; Part II. 1. Fatigue; Part III. Major Neurological Conditions Requiring Palliation; Part IV. Ethical Issues; Part V. Appendices.

2005 228 x 152 mm 276pp 8 figures978-0-521-67249-8 Paperback £31.99

Page 6: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Plasticity in the Human Nervous SystemInvestigations with Transcranial Magnetic StimulationEdited by Simon BonifaceAddenbrooke’s Hospital, Cambridge

and Ulf ZiemannJohann Wolfgang Goethe-Universität Frankfurt

Transcranial magnetic stimulation (TMS) is a non-invasive and painless technique that has opened up completely new and fascinating avenues to study neural plasticity. Current knowledge of all these exciting possibilities is brought together in this book, written by the world’s leading experts in the field. The book is an essential compendium on plasticity of the human brain in health and disease, for clinical neurophysiologists, neurologists, psychiatrists and neuroscientists.• Bringstogethertwokeyareasinclinical

neuroscience,plasticityandTMS

• Contributorsareworldleadersinthefield

• Ofessentialinteresttoneuroscientistsandclinicians

Contents: 1. The nature and mechanisms of plasticity; 2. Techniques of transcranial magnetic stimulation; 3. Developmental plasticity of the corticospinal system; 4. Practice induced plasticity in the human motor cortex; 5. Skill learning; 6. Stimulation induced plasticity in the human motor cortex; 7. Lesions of cortex and post-stroke reorganisation; 8. Lesions of the periphery and the spinal cord; 9. Functional relevance of cortical plasticity; 10. Therapeutic uses of rTMS; 11. Rehabilitation; 12. New questions.

2003 247 x 174 mm 328pp 47 line diagrams 7 half-tones 2 tables978-0-521-80727-2 Hardback £90.00

The Frontal LobesDevelopment, Function and PathologyEdited by Jarl RisbergLunds Universitet, Sweden

and Jordan GrafmanNational Institute of Health, Bethesda, MD, USA

The frontal lobes and their functional properties are recognised as crucial to establishing our identity as autonomous human beings. This book provides a broad introductory overview of this unique brain region. In an accessible and readable style it covers the evolutionary significance of the frontal lobes, typical and atypical development pathways, the role played in normal cognition, memory and emotion, and in damaged states, resulting in a range of neurological syndromes and psychiatric disturbances. An introductory book for students of neuropsychology and practicing clinicians.• Anintroductorybookthatcontainsup-to-

dateinformationaboutsomemajorfieldswithinfrontalloberesearch

• Containstheoreticalchaptersandchaptersaboutclinicalaspectsonfrontallobedysfunction

• Coversthefullhumanlifespananddiscussesevolutionaryaspectsonfrontallobefunctions

Contents: Foreword; Introduction; 1. Evolutionary aspects on the frontal lobes; 2. Organization of the principal pathways of prefrontal lateral, medial and orbitofrontal cortices in primates and implications for their collaborative interaction in executive function; 3. Human prefrontal cortex: processes and representations; 4. A microcircuit model of prefrontal functions: ying and yang of reverberatory neurodynamics in cognition; 5. Prefrontal cortex: typical and atypical development; 6. Case studies of focal pre-frontal lesions in man; 7. Left pre-frontal function and semantic organization during encoding and retrieval in healthy and psychiatric populations; 8. Clinical symptoms and neuropathology in organic dementing disorders affecting the frontal lobes.

Series for the International Neuropsychological Society

2006 247 x 174 mm 240pp 13 line diagrams 2 half-tones978-0-521-67225-2 Paperback £35.00

Central Pain SyndromePathophysiology, diagnosis and managementSergio CanaveroUniversity of Turin, Molinette Hospital, Turin, Italy

and Vincenzo BonicalziTurin Advanced Neuromodulation Group, Turin, Italy

Central Pain Syndrome is a neurological condition caused by damage specifically to the central nervous system – brain, brainstem, or spinal cord. This is the only up-to-date book available on the clinical aspects (including diagnosis and therapy) of CPS management. The authors have developed a very complete reference source on central pain, which includes background material, pathophysiology, and diagnostic and therapeutic information. • Anup-to-datereferenceavailableonCPS

management

• Pathologyanditsmanagementarehotissuesatthistimeandwillmakethisreferenceanessentialpurchase

• Offersmuchoftheinformationintabularformforquickandeasyreference

Contents: 1. Introduction; 2. Central pain of brain origin; 3. Central pain of cord origin; 4. Diagnosing central pain; 5. Drug therapy; 6. Neuromodulation; 7. Pathophysiology; 8. Piecing together the evidence.

2007 253 x 177 mm 396pp 36 tables978-0-521-86692-7 Hardback £50.00

NeUroSCIeNCe

Page 7: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Handbook of experimental NeurologyMethods and Techniques in Animal researchEdited by Turgut TatlisumakHelsinki University Central Hospital

and Marc FisherUniversity of Massachusetts

This major new handbook covers, for the first time in one volume, every major methodology and disease model used in current neuroscience research. Written by a panel of 60 internationally regarded scientists, this book delivers critical, up-to-the-minute, methodological information and describes small animal models for almost all major neurological diseases. This book forms an essential reference volume for all neuroscientists, from beginning students to experienced researchers and professionals.• Basicrelevantinfomation,includingclearly

labelleddiagrams

• Allmajordiseasemodelsandmethodologiesinonevolume

• writtenforbeginnersandyoungscientists

Contents: Part I. Principles and General Methods; Part II. Experimental Models of Major Neurological Diseases.

2006 247 x 174 mm 594pp 18 line diagrams 19 half-tones 23 tables978-0-521-83814-6 Hardback £130.00

The Brain and BehaviorAn Introduction to Behavioral NeuroanatomySecond editionDavid ClarkOhio State University

Nashaat BoutrosWayne State University, Detroit

and Mario MendezUniversity of California, Los Angeles

This new edition of The Brain and Behavior builds on the success of the previous edition and retains the core aim of providing an accessible introduction to behavioral neuroanatomy. The text is presented in a highly structured and organised format to help the reader distinguish between issues of anatomical, behavioural and physiological relevance. Simplified and clear diagrams are provided throughout the chapters to illustrate key points. Case examples are explored to set the neuroanatomy in the context of clinical experience.

‘Thedetailsarecomprehensiveinrelationtoadheringtothetitleitself,TheBrainandBehaviouranditisaveryimportantreadforallphysiciansworkinginNeurology,Psychiatry,FamilyMedicineandClinicalPsychology…Thebookisinformative,useful,writteninaveryscientificwayandcontainsinformationthatisimportanttoknow.Itisdefinitelyworthbuying.’

neurosciences

Contents: 1. Introduction; 2. Gross anatomy of the brain; 3. Histology; 4. Occipital and parietal lobes; 5. Temporal lobe-neocortical structures; 6. Frontal lobe; 7. Basal ganglia; 8. Diencephalon: hypothalamus and epithalamus; 9. Diencephalon: thalamus; 10. Brainstem; 11. Limbic system: temporal lobe; 12. Limbic system: cingulate cortex; 13. Limbic system: overview; 14. Interhemispheric connections and laterality.

2005 246 x 189 mm 278pp 76 line diagrams 21 half-tones 6 colour plates978-0-521-54984-4 Paperback £38.00978-0-521-84050-7 Hardback £70.00

The ThalamusSecond editionEdward G. JonesUniversity of California, Davis

Edward G. Jones’ The Thalamus is one of the most cited publications in neuroscience. Now more than 20 years on from its first printing, the author has completely rewritten his landmark volume, incorporating the numerous developments in research and understanding of the mammalian thalamus. Available as a 2 volume boxed set, this is an up-to-date scientific review of virtually all aspects of forebrain function and a work of immense neuroscientific scholarship. Essential for neuroanatomists, neurophysiologists, molecular neurobiologists, developmental neurobiologists and clinicians, its deep historical perspective will be of value to historians of science.• Containsahugerangeofphotographic

examplesofthalamicstructure,fromcommonanimalspeciesandhumans,toraritiessuchasthemonotremes

• Completelyup-to-date,incorporatingnewdetailsofmolecularandgeneticmechanismsofforebraindevelopment

• Aunique,one-personperspectivefromaleadingauthorityonthescience,historyandliteratureofthisfascinatingtopic

Contents: Part I. History; Part II. Fundamental Principles; Part III. Development; Part IV. Individual Thalamic Nuclei; Part V. Comparative Structure; Part VI. Conclusions.

2007 276 x 219 mm 1708pp 555 half-tones 18 tables978-0-521-85881-6 Hardback set £280.00

Page 8: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

The Circuitry of the Human Spinal CordIts role in Motor Control and Movement DisordersEmmanuel Pierrot-DeseillignyGroupe Hospitalier Pitié-Salpétrière, Paris

and David BurkeUniversity of Sydney

This comprehensive reference surveys the literature related to the control of spinal cord circuits in humans, showing how they can be studied, their role in normal movement, and how they malfunction in disease states. Chapters are highly illustrated and consistently organised, reviewing, for each pathway, the experimental background, methodology, organisation and control, role during motor tasks, and changes in patients with CNS lesions. Each chapter concludes with a helpful resume. This will be essential reading for research workers and clinicians involved in the study, treatment and rehabilitation of movement disorders.

‘EmmanuelPierrot-DeseillignyandDavidBurke’simportantnewbookrepresentsareviewofmanyrecentdevelopmentsintheworkingsofthehumanspinalcord.Theworkreviewedisverymuchcentredontheoutstandingachievementsthatthesetwointernationalleadershavecontributedtothefield…Thisbookwillbecomeauniqueresource,makingavailableinonevolumesomanyimportantpublishedstudies.’

brain

Contents: 1. General methodology; 2. Monosynaptic Ia excitation and post-activation depression; 3. Muscle spindles and fusimotor drive: microneurography and other techniques; 4. Recurrent inhibition; 5. Reciprocal Ia inhibition; 6. Ib pathways; 7. Group Ii pathways; 8. Presynaptic inhibition of Ia terminals; 9. Cutaneomuscular, withdrawal and flexor reflex afferent responses; 10. Propriospinal relay for descending motor commands; 11. Involvement of spinal pathways in different motor tasks; 12. The pathophysiology of spasticity and parkinsonian rigidity.

2005 246 x 189 mm 664pp 138 line diagrams 3 half-tones 10 tables978-0-521-82581-8 Hardback £125.00

The Neuropathology of DementiaSecond editionEdited by Margaret M. EsiriUniversity of Oxford

Virginia M. -Y. Lee and John Q. TrojanowskiBoth from University of Pennsylvania School of Medicine

Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world’s leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia.

Fromreviewsofthefirstedition:‘Thisup-to-dateandauthoritativeaccountwillbeinvaluableforpractisingneuropathologistsandatreasuredworkofreferenceforpsychiatristsandneuroscientistswithaninterestindementia.’

international journal of geriatric psychiatry

Contents: Preface; 1. Definition, clinical features and neuroanatomical basis of dementia; 2. Important anatomical landmarks in the brain in dementia; 3. Practical approach to pathological diagnosis; 4. Morphometric methods and dementia; 5. Safety precautions in laboratories involved with dementia diagnosis and research; 6. Molecular diagnosis of dementia 7. Neuropathology of the aging brain; 8. Neuroimaging Alzheimer’s disease; 9. Alzheimer’s disease; 10. Down’s syndrome and Alzheimer’s disease; 11. Sporadic tauopathies: Pick’s disease, corticobasal degeneration, progressive supranuclear palsy and argyrophilic brain disease; 12. Hereditary tauopathies and idiopathic frontotemporal dementias; 13. Vascular dementias; 14. Familial and sporadic cerebral amyloid angiopathies associated with dementia and the BRI dementias; 15. Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy and the spectrum of diseases with alpha-synuclein inclusions; 16. Huntington disease; 17. Human prion diseases; 18. Alcoholism and dementia; 19. Hydrocephalus and dementia; 20. Head injury and dementia; 21. Infectious (and inflammatory) diseases causing dementia; 22. Schizophrenia and dementia; 23. Other diseases that cause dementia; 24. Transgenic mouse models of neurodegenerative disease; Appendix: Dementia brain banks; Index.

2004 276 x 219 mm 584pp 52 line diagrams 111 half-tones978-0-521-81915-2 Hardback £225.00

Page 9: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Neural Basis of Semantic MemoryEdited by John HartUniversity of Texas, Dallas

and Michael A. KrautThe Johns Hopkins University School of Medicine

Presenting a collection of the leading models of how the human brain encodes for the memory of the items that surround us in everyday life. These models of brain function have been composed from the world’s leading experts based upon findings from new investigative techniques.• Includesopinionsformultipleinvestigative

techniquesonthesamememoryfunction

• Chapterscovernormaltobraindamagedmemoryfunction

• Allowsforfullspectrumperspectiveofmemory

Contents: A. Semantic memory: Building Models from Lesions: 1. Semantic refractory access disorders 2. The anatomical locus of lesion in category-specific semantic disorders and the format of the underlying conceptual representations; B. Insights from Electrophysiology: 3. Functional modularity of semantic memory revealed by event-related brain potentials; 4. Bilingual semantic memory revisited – ERP and fMRI evidence; C. Applications of Models to Understanding Cognitive Dysfunction: 5. Schizophrenia and semantic memory D. Representations of Nouns and Verbs vs. Objects and Actions: 6. Effects of word imageability on semantic access: neuroimaging studies; 7. The neural systems processing tool and action semantics; 8. The semantic representation of nouns and verbs; E. Critical Role of Subcortical Nuclei in Semantic Functions: 9. Role of the basal ganglia in language and semantics: supporting cast; F. Conceptual Models of Semantics: 10. Process and content in semantic memory; 11. The conceptual structure account: a cognitive model of semantic memory and its neural instantiation; 12. Neural foundations for conceptual representations: evidence from functional brain imaging; 13. Neural hybrid model of semantic object memory (version 1.1).

2007 247 x 174 mm 394pp 15 line diagrams 16 half-tones 3 tables978-0-521-84870-1 Hardback £55.00

olfaction and the BrainEdited by Warrick J. BrewerUniversity of Melbourne

David CastleUniversity of Melbourne

and Christos PantelisSunshine Hospital, Melbourne

Foreword by Peter DohertyOlfaction is of particular interest to specialists in schizophrenia. Clear deficits in the sense of smell could be used to predict schizophrenia in the future. In this timely book, Warrick Brewer and his team of experts set out our current understanding of olfaction and mental health, including where it may take us in the future. All aspects of olfactory function and dysfunction are covered, drawing on the latest neuroimaging techniques where appropriate. • Comprehensivecoverageoftheprinciplesof

smellandtheassociationbetweenneuralstructureandpracticalitiesofhigher-orderfunction

• Outlinesthefuturementalhealthpossibilitiesanddirectionsforresearch,diagnosisandtreatment

• Multidisciplinary,tocoverthebroadrangeofimplications

Contents: Part I. Neurology, Neurophysiology and Neuropsychology – Olfactory Clues to Brain Development and Disorder; Part II. Social Functioning; Part III. Assessment and Disorders of Olfaction.

2006 247 x 174 mm 382pp 44 line diagrams 48 figures978-0-521-84922-7 Hardback £65.00

Brain NorepinephrineNeurobiology and TherapeuticsEdited by Gregory A. OrdwayEast Tennessee State University

Michael A. SchwartzUniversity of Hawai’i, Manoa

and Alan FrazerUniversity of Texas Health Science Center, San Antonio

Norepinephrine is a chemical neurotransmitter. Noradrenergic drugs have been proven effective for depression and ADHD, and drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects for new disease indications. Recent discoveries about norepinephrine’s contribution to health, disease, and therapy make this synthesis of evidence, practice and research very timely. The book is divided into four sections: basic biology; norepinephrine’s role in behavior; its role in CNS diseases, and the pharmacology and therapeutics of noradrenergic drugs for psychiatric and neurological disorders.• Up-to-the-minutereviewofthebiologyof

centralnervoussystemnorepinephrine

• Givespracticalguidanceabouttheuseofnorepinephrinedrugsinavarietyofneurologicandpsychiatricdisorders

• Combinesthebasicbiologyofnorepinephrinewiththetherapeuticsofnorepinephrine-actingdrugs

Contents: Part I. The Neurobiology of Norepinephrine; Part II. Norepinephrine and Behavior; Part III. The Biology of Norepinephrine in CNS Pathology; Part IV. Psychopharmacology of Norepinephrine.

2007 216 x 138 mm 658pp 25 tables 80 figures978-0-521-83491-9 Hardback £95.00

Page 10: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

NeUroPSyCHIATry / NeUroPSyCHoLogyThe Clinical Neuropsychiatry of StrokeCognitive, Behavioral and emotional Disorders following Vascular Brain InjurySecond editionRobert G. RobinsonCollege of Medicine, University of Iowa

Fully revised, this new edition covers the range of neuropsychiatric syndromes associated with stroke, including cognitive, emotional and behavioural disorders such as depression, anxiety and psychosis. Since the last edition there has been an explosion of published literature on this topic and the book provides a comprehensive, systematic and cohesive review of this new material. There is a growing recognition among a wide range of clinicians and allied healthcare staff that post-stroke neuropsychiatric syndromes are common and serious. Such complications can have a negative impact on recovery and even survival.

‘…thereaderenjoysastructuredapproach,withsectionsonprevalenceandmechanismofthedisorder,beforediscussionoftreatment.Casehistoriescomplementthetextthroughout.Figures,mainlygraphical,areclearandwellused.’

acta neurochirurgica

Contents: 1. Recent trends in the epidemiology of stroke; 2. Historical perspective; 3. Brain organization and cerebral basis of emotion; 4. Vascular anatomy and classification of stroke; 5. Diagnosis of depression; 6. Prevalence of depressive disorders; 7. Phenomenology and specificity of depressive disorders; 8. Natural course of depression; 9. Delayed-onset depression (proofed); 10. Relationship to lesion location; 11. Relationship of depression to cerebral dominance and structural asymmetries; 12. Relationship of depression to bilateral hemisphere brain injury; 13. Relationship of depression to physical impairment; 14. Relationship to cognitive impairment and treatment; 15. Relationship of aphasia to depression; 16. Relationship of depression to social functioning; 17. Relationship to premorbid risk factors; 18. Mortality and treatment; 19. Suicidal thoughts and plans; 20. Biological markers; 21. Mechanisms of poststroke depression; 22. Treatment of poststroke depression; 23. Prevention of poststroke depression; 24. Prevalence and clinical symptoms; 25. Clinical and lesion correlates of poststroke mania; 26. Bipolar disorder following stroke; 27. Mechanism of mania following stroke; 28. Treatment of mania following stroke; 29. Prevalence and specificity of clinical symptoms; 30. Clinical and lesion correlates; 31. Longitudinal course; 32. Relationship of anxiety to outcome; 33. Mechanism and treatment of poststroke anxiety disorder; 34. Psychosis; 35. Anosognosia and denial of illness; 36. Catastrophic reaction; 37. Apathy; 38. Disturbance of prosody; 39. Irritability and aggression; 40. Pathological laughing and crying; 41. Summary and future directions.

2006 247 x 174 mm 480pp 140 figures978-0-521-84007-1 Hardback £90.00

Pediatric Neuropsychological InterventionEdited by Scott J. HunterUniversity of Chicago

and Jacobus DondersMary Free Bed Rehabilitation Hospital, Grand Rapids

Pediatric neuropsychology is the practice of understanding and elucidating brain-behavior relationships as applied to children and adolescents. This volume examines current trends in the assessment and treatment of common disorders including traumatic brain injuries, brain tumors, epilepsy and autistic spectrum disorders. Its primary aim is to help practitioners and researchers identify and understand the evidence to support interventions with a range of acquired or congenital neuropsychological disorders. This is essential reading for pediatric neuropsychologists, child clinical psychologists and school psychologists, as well as pediatric neurologists and psychiatrists.• Coverstheassessmentandtreatmentof

neurodevelopmentaldisorders

• Emphasisesevidence-basedinterventions

• Bridgestheknowledgegapsbetweentheprofessionalsresponsibleforprovidingcare

Contents: Part I. Fundamentals of Pediatric Neuropsychological Intervention; Part II. Managing Neurocognitive Impairments in Children and Adolescents; Part III. Medical, Rehabilitative and Experimental Interventions; Part IV. Future Directions.

2007 247 x 174 mm 508pp 3 line diagrams 3 half-tones 14 tables978-0-521-87550-9 Hardback £60.00

Page 11: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

The Clinical Neuropsychiatry of Multiple SclerosisSecond editionAnthony FeinsteinUniversity of Toronto

Multiple sclerosis is the most common cause of neurological disability in young and middle-aged adults. This fully updated and revised new edition provides a detailed account of the many neuropsychiatric disorders associated with MS and is relevant to both the research and the clinical setting. Using the latest brain imaging findings and results from treatment trials, it will be valuable to all mental health professionals, neurologists, and others caring for those affected by MS.

‘Thisisaclinicallyorientedvolume,whichiswellresearched,writtenandedited…FeinsteinshouldbecongratulatedforhiseffortinreviewingandbringingtogetherwhatisknownofthepsychiatryofMS…’

british journal of psychiatry

Contents: Foreword G. Comi; 1. Multiple sclerosis: diagnosis and definitions; 2. Depression: prevalence, symptoms, diagnosis and clinical correlates; 3. Depression: aetiology and treatment; 4. Multiple sclerosis, bipolar affective disorder and euphoria; 5. Multiple sclerosis and pseudobulbar affect; 6. Multiple sclerosis and psychosis; 7. Cognitive impairment in multiple sclerosis; 8. The natural history of cognitive change in multiple sclerosis; 9. Cognitive impairment in multiple sclerosis: detection, management and significance; 10. Neuroimaging correlates of cognitive dysfunction; 11. Multiple sclerosis, disease modifying treatment and behavioral change; 12. Multiple sclerosis: a subcortical, white matter dementia?

2007 247 x 174 mm 274pp 6 line diagrams 16 half-tones 13 tables 27 figures978-0-521-85234-0 Hardback £55.00

The Neuroscience of Psychological TherapiesRowland FolensbeeBaylor College of Medicine

A practical and detailed text of facts and concepts aiming to help clinicians develop a basic understanding of brain function and its relevance to conducting therapy and assessment. This book describes how specific locations in the brain carry out specific activities, how the different activities produce normal and pathological behavior and how knowledge of brain activities can guide psychological assessment and intervention. The readership will include professionals practising in mental health, neuroscience researchers as well as graduates of mental health disciplines.

‘Inthissuperbnewvolume,rowlandFolensbeefunctionsasatourguidetothereader.Hetakeshisreadersonanenjoyableandstimulatingjourneythroughthebrainandcontemporaryneurosciencewhileavoidingbothcondescensionandobfuscation.Inaneminentlyreadableprosestyle,heillustrateshowanunderstandingofthebraincanilluminatethedarkrecessesofthehumanmindthatemergeinpsychotherapeutictreatment.’

glen o. gabbard, baylor college of medicine

Contents: Acknowledgements; 1. Introduction; 2. Neuropsychological concepts; 3. Neural networks; 4. Memory and learning; 5. Affect; 6. Anxiety; 7. Processes of brain development; 8. Themes of brain development; 9. Basic concepts: summary and integration; 10. Introduction to neuroscience applications in psychotherapy; 11. Intake and assessment; 12. Neural networks in therapy; 13. Affect in therapy; 14. Memory and change; 15. Anxiety and change; 16. The experience of improvement in psychotherapy; 17. The therapist’s neuroscience; 18. Communicating with patients through neuroscience; 19. Integrating traditional therapies; 20. Applying neuroscience to depression intervention; 21. Neuroscience and psychotherapy: moving forward; Appendix 1. Neuroimaging and psychological therapies.

2007 228 x 152 mm 234pp 13 line diagrams 1 half-tone 2 tables978-0-521-68188-9 Paperback £21.99 978-0-521-86317-9 Hardback £60.00

Page 12: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Progress in Neurotherapeutics and NeuropsychopharmacologyVolume 1Edited by Jeffrey L. CummingsUniversity of California, Los Angeles

An essential update of recent clinical trials in the management of neurological and neuropsychiatric disorders.Contents: Preface; Introduction to Neurotherapeutics and Neuropharmacology; 1. Rivastigmine in the treatment of dementia associated with Parkinson’s disease: a randomized, double-blind, placebo-controlled study; 2. Modafinil for the treatment of fatigue in multiple sclerosis; 3. Radiotherapy with concurrent and adjuvant temozolomide: a new standard of care for glioblastoma multiform; 4. Treating migraine attacks ASAP: concept and methodological issues; 5. Early phase trials of minocycline in amyotropic lateral sclerosis; 6. Creatine as a potential treatment for amyotrophic lateral sclerosis; 7. AVP-923 as a novel treatment for pseudobulbar affect ALS; 8. Liquid fluoxetine vs. placebo for repetitive behaviors in childhood autism; 9. Testing multiple novel mechanisms for treating schizophrenia in a single trial; 10. Selegiline in the treatment of negative symptoms of schizophrenia; 11. Analysis of the cognitive enhancing effects of modafinil in schizophrenia; 12. Efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatient with schizophrenia or schizoaffective disorder: results of a double-blind, 6-week study, with a 6-month, double-blind, continuation phase.

2006 247 x 174 mm 184pp978-0-521-86253-0 Hardback £60.00

Progress in Neurotherapeutics and Neuropsycho-pharmacologyVolume 2Edited by Jeffrey L. CummingsUniversity of California, Los Angeles

Volumes in this series provide readers with updates of recent clinical trial results, impacts of trials on guidelines and evidence-based practice, advances in trial methodologies, and the evolution of biomarkers in trials. The series focuses on trials in neurotherapeutics, including disease-modifying and symptomatic agents for neurological diseases, psychopharmacological management of neurologic and psychiatric illnesses, and non-drug treatments. It is an essential update of recent trials in all aspects of the management of neurologic and neuropsychiatric disorders, and thus an invaluable resource for clinicians and neuroscientists.• Annualupdateonclinicaltrialsinneurotherapeuticsand

psychopharmacology

• Providestheevidenceonwhichtobasetreatments

• Essentialresourceforcliniciansandneuroscientists

Contents: 1. Progress in Neurotherapeutics and Neuropsychopharmacology 2007; 2. A randomized trial comparing unilateral pallidotomy with bilateral subthalamic nucleus stimulation in PD: perspectives for future implication in clinical practice; 3. The Phase II futility clinical trial design; 4. Clinical trials in dementia; 5. Comparative neuropsychological effects of Lamotrigine and Topiramate in healthy volunteers; 6. Pilot clinical trial of NT-3 in CMT1A patients; 7. New Directions in Pediatric Neuro-Oncology Practice: Impact of the Children’s Cancer Group Study 9933, a Phase II Study of High-Dose Chemotherapy before Radiation in Children with Newly Diagnosed High-Grade Astrocytoma; 8. Chemoradiotherapy for primary CNS lymphoma; 9. A double-blind, randomized clinical trial to assess the augmentation with Nimodipine of antidepressant therapy in the treatment of ‘vascular depression’; 10. Repetitive transcranial magnetic stimulation: a novel, noninvasive add-on treatment for medication-resistant depression; 11. The NIMH MATRICS initiative: development of a consensus cognitive battery; 12. Review of a randomized-controlled trial of adjunctive Bupropion in the treatment of SSRI-induced sexual dysfunction; 13. Trial-based advances in the treatment of bipolar depression; 14. Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of Risperidone monotherapy; 15. Olanzapine as maintenance therapy in patients with bipolar I disorder; 16. Can quality of life be improved in schizophrenia? Results from a pragmatic, randomized controlled trial comparing Olanzapine with first generation antipsychotics; 17. Combined behavioral and pharmacological treatment of opioid-dependent adolescents: a randomized, controlled trial.

2007 247 x 174 mm 284pp978-0-521-86254-7 Hardback £75.00

Page 13: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Textbook of Neural repair and rehabilitationVolume 1: Neural repair and PlasticityEdited by Michael SelzerUniversity of Pennsylvania

Stephanie ClarkeUniversité de Lausanne, Switzerland

Leonardo CohenNational Institute of Neurological Disorders and Stroke, Bethesda, Maryland

Pamela DuncanUniversity of Florida

and Fred GageThe Salk Institute, California

This volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing plasticity in the normal CNS, mechanisms of neuronal death, axonal regeneration, stem cell biology, and neuron replacement. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.

‘Intwofreestandingbutlinkedvolumes,TextbookofNaturalrepairandrehabilitationprovidescomprehensivecoverageofthescienceandpracticeofneurologicalrehabilitation.Editedandwrittenbyleadinginternationalauthoritiesfromtheneurosciencesandclinicalneurorehabilitation,thetwo-volumesetisanessentialresourceforrehabilitationprofessionalsandacomprehensivereferenceforallscientistsandcliniciansinthefield.’

advances in clinical neuroscience and rehabilitation

Contents: Part A. Neural plasticity; Part A1. Cellular and molecular mechanisms of neural plasticity; Part A2. Functional Plasticity in CNS System; Part B. Neural Repair; Part B1. Basic Cellular and Molecular Processes; Part B2. Determinants of Regeneration in the Injured Nervous System; Part B3. Promotion of Regeneration in the Injured Nervous System; Part B4. Translational Research.

2006 246 x 189 mm 724pp 56 line diagrams 28 half-tones 12 tables978-0-521-85641-6 Hardback £110.00

Textbook of Neural repair and rehabilitationVolume 2: Medical NeurorehabilitationEdited by Michael SelzerUniversity of Pennsylvania

Stephanie ClarkeUniversité de Lausanne, Switzerland

Leonardo CohenNational Institute of Neurological Disorders and Stroke, Bethesda, Maryland

Pamela DuncanUniversity of Florida

and Fred GageThe Salk Institute, California

Medical Neurorehabilitation, can stand alone as a clinical handbook for neurorehabilitation. It covers the practical applications of the basic science principles presented in volume 1, provides authoritative guidelines on the management of disabling symptoms, and describes comprehensive rehabilitation approaches for the major categories of disabling neurological disorders. This book and its companion are an essential resource for neuroscientists and provide a foundation for the work of clinical neurorehabilitation professionals.• Comprehensivereferencetextcoveringbasicscienceandmedical

neurorehabilitation

• Secondoftwofreestandingvolumes,servesasaclinicalhandbookforneurorehabilitation

• Describescomprehensiverehabilitationapproachesformajordisablingdisorders

Contents: Part A. Technology of Neurorehabilitation; Part A1. Outcomes Measurement and Diagnostic Technology; Part A2. Therapeutic Technology; Part B. Symptom-specific Neurorehabilitation; Part B1. Sensory and Motor Dysfunctions; Part B2. Vegetative and Autonomic Dysfunctions; Part B3. Cognitive Neurorehabilitation; Part C. Disease-specific; Neurorehabilitation Systems.

2006 246 x 189 mm 790pp 61 line diagrams 46 half-tones 45 tables978-0-521-85642-3 Hardback £110.00

SAVE£40.00!•BUYTHETwO-VOLUMESET

Textbook of Neural repair and rehabilitationThis two-volume set is an essential resource for rehabilitation professionals and scientists in the field.

2006 247 x 174 mm 1520pp978-0-521-83639-5 Hardback £180.00

NeUroreHABILITATIoN

Page 14: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

Upper Motor Neurone Syndrome and SpasticityClinical Management and NeurophysiologyEdited by Michael P. Barnesand Garth R. JohnsonBoth from University of Newcastle upon Tyne

A reference and guide for clinicians, therapists, orthotists, bioengineers and all other health professionals involved in the management of spasticity. It is a thorough review, ranging in coverage from physiotherapy, seating, and orthoses, the use of drugs, and the neurophysiology of spasticity, to measurement of outcome and the newer treatment techniques (such as phenol and alcohol nerve blocks and botulinum toxin injections). More invasive procedures, including intrathecal baclofen and surgery, are covered in detail, and the final chapter looks closely at the management of spasticity in children.Contents: Preface; 1. An overview of the clinical management of spasticity; 2. Neurophysiology of upper motor neurone syndrome and spasticity; 3. Measurement of spasticity; 4. Physiotherapy approaches to spasticity; 5. Seating and positioning in spasticity; 6. Orthoses, splinting and casting in spasticity; 7. Pharmacological management of spasticity; 8. Chemical neurolysis in the management of spasticity; 9. The use of botulinum toxin in spasticity; 10. Intrathecal baclofen for control of spinal and supra spinal spasticity; 11. Surgical management of spasticity; 12. Management of spasticity in children; Index.

2001 247 x 174 mm 328pp 33 half-tones 9 tables 14 graphs 30 figures978-0-521-79427-5 Paperback £50.00

NeUroIMAgINgCarotid DiseaseThe role of Imaging in Diagnosis and ManagementEdited by Jonathan GillardUniversity of Cambridge

Martin GravesUniversity of Cambridge

Thomas HatsukamiUniversity of Washington

and Chun YuanUniversity of Washington

Stroke is major cause of morbidity and mortality, with carotid disease representing an important contributory risk factor. This book is about the pathogenesis and management of carotid disease with specific focus on the role imaging has to play in the early recognition of symptomatic and asymptomatic disease as well as treatment of the developed condition. This book should be read by all those involved in the treatment of patients with carotid disease as well as those involved in researching and developing new therapeutic approaches. • Providescomprehensivecoverageofthe

widestrangeofimagingmodalities.

• Criticallyreviewstherolesthesecanplayinrecognisingandmanagingcarotiddisease.

• writtentobeaccessibletoclinicians,surgeonsandresearchers.

• Highlyillustratedthroughout

2006 246 x 189 mm 556pp 68 half-tones 24 tables978-0-521-86226-4 Hardback £120.00

Community rehabilitation in NeurologyMichael P. Barnesand Harriet RadermacherBoth from University of Newcastle upon Tyne

This book analyses community rehabilitation needs from many different perspectives, including the views of disabled people, rehabilitation clinicians and service providers. Many examples of community rehabilitation schemes are presented, with evidence for their effectiveness, and case studies are used to highlight the main issues. The authors take an international view, and there are chapters dealing with the disabled child in the community and with neuropsychological rehabilitation. The first book to examine the growing trend towards community rehabilitation in neurology, it is directed towards all clinicians involved with neurorehabilitation.

‘Thetextprovidesthereaderwithavastamountofinformationonneurologicalrehabilitationincludingmanythought-provokingideas.’

physiotherapy

Contents: 1. Background to community neurological rehabilitation; 2. Neurological rehabilitation: basic principles and models of delivery; 3. Models of disability; 4. Concepts of community; 5. The views of disabled people; 6. Outcome measures and research in the community; 7. Evidence base for community neurological rehabilitation; 8. Lessons from the South; 9. Other aspects of community neurological rehabilitation; 10. Community rehabilitation in childhood: concepts to inform practice; 11. Neuropsychological rehabilitation in the community; 12. The way forward.

2003 228 x 152 mm 262pp 6 tables978-0-521-80874-3 Hardback £67.00

Page 15: Neurology · Walton Centre for Neurology and Neurosurgery, Liverpool A pocket-sized ready-reference to neurology. Organised from A to Z, the content consists of a series of entries,

NeUroIMAgINgThalamus and related Systemsjournals.cambridge.org/THL

The International Journal of Neuro-psychopharmacology journals.cambridge.org/PNP

Journal of the International Neuropsychological Society journals.cambridge.org/INS

Behavioral and Brain Science journals.cambridge.org/BBS

Visual Neuroscience journals.cambridge.org/VNS

Psychological Medicine journals.cambridge.org/PSM

For sample copies and ordering information for journals visit

journals.cambridge.org

JoUrNALSClinical Mr NeuroimagingDiffusion, Perfusion and SpectroscopyEdited by Jonathan H. GillardUniversity of Cambridge

Adam D. WaldmanCharing Cross Hospital, London

and Peter B. BarkerThe Johns Hopkins University

The physiological magnetic resonance techniques of diffusion imaging, perfusion imaging and spectroscopy offer insights into brain structure, function and metabolism. This book provides the reader with a thorough review of the underlying physical principles of each of these methods, as well as comprehensive coverage of their clinical applications. Attention is also drawn to possible artifacts and pitfalls associated with these techniques. This book is an essential reference work for radiologists, neurologists, neurosurgeons and psychiatrists who use these techniques, as well as medical researchers, residents and fellows.

‘…abook…addressingboththetechnicalaspectsofdiffusion,perfusionandspectroscopyandtheirclinicalapplications…ThisdetailedtextofferschaptersfromawiderangeofeminentauthorsfrombothsidesoftheAtlantic…Icanhighlyrecommendthisbooktothosewishingtolearnmoreaboutthetechnicalaspectsandclinicalapplicationsofdiffusion,perfusionandspectroscopy.’

acta neurochirugica

Contents: Foreword; Introduction; 1. Fundamentals of MR spectroscopy; 2. Quantification and analysis in MR spectroscopy; 3. Artifacts and pitfalls in MR spectroscopy; 4. Fundamentals of diffusion MR imaging; 5. MR tractography using diffusion tensor MR imaging; 6. Artifacts and pitfalls in diffusion MR imaging; 7. Cerebral perfusion imaging by exogenous contrast agents; 8. MRI detection of regional blood flow using arterial spin labeling; 9. Artifacts and pitfalls in perfusion MR imaging; 10. Cerebrovascular disease: overview; 11. MR spectroscopy in stroke; 12. Diffusion and perfusion MR in stroke; 13. Arterial spin labeling in stroke; 14. Magnetic resonance diffusion tensor imaging in stroke; 15. 15. MR spectroscopy in severe obstructive carotid artery disease; 16. Perfusion and diffusion imaging in chronic carotid disease; 17. Imaging migraine pathogenesis; 18. Adult neoplasia: overview; 19. MR spectroscopy of brain tumors in adults; 20. Diffusion MR imaging in adult neoplasia; 21. Perfusion MR imaging in adult neoplasia; 22. Physiological imaging in infection, inflammation and demyelination: overview; 23. MR spectroscopy in intracranial infection; 24. The role of diffusion-weighted imaging in intracranial infection; 25. MR spectroscopy in demyelination and inflammation; 26. Diffusion imaging in demyelination and inflammation; 27. Physiological MR to evaluate HIV-associated brain disorders; 28. Seizure disorders: overview; 29. MR spectroscopy in seizure disorders; 30. Diffusion and perfusion MR imaging in seizure disorders; 31. Psychiatric and neurodegenerative disease: overview; 32. MR spectroscopy in psychiatry; 33. Diffusion MR imaging in psychiatry and aging; 34. MR spectroscopy in aging and dementia; 35. MR spectroscopy in neurodegeneration; 36. Potential role of MR spectroscopy, diffusion weighted/diffusion tensor imaging and perfusion weighted imaging in traumatic brain injury: overview; 37. MR spectroscopy in traumatic brain injury; 38. Diffusion- and perfusion-weighted MR imaging in head injury; 39. Physiological MR of the pediatric brain: overview; 40. Physiological MRI of normal development and developmental delay; 41. MR spectroscopy of hypoxic brain injury; 42. The role of diffusion and perfusion weighted brain imaging in neonatology; 43. Physiological MR of pediatric brain tumors; 44. Physiological MRI techniques and pediatric stroke; 45. MR spectroscopy in pediatric white matter disease; 46. MR spectroscopy of inborn errors of metabolism.

2004 276 x 219 mm 852pp 31 tables 333 figures978-0-521-82457-6 Hardback £205.00

To appear in Volume 29, Number 6 (2006)Offprints of the following forthcoming BBS treatments can be purchased for educational purposes if they are ordered well in advance. For ordering information, pleasewrite to Journals Department, Cambridge University Press, 32 Avenue of the Americas, New York, NY 10013-2473

Why ritualized behavior? Precaution systems and action parsing in developmental, pathological and cultural ritualsPascal Boyer & Pierre Lienard, Washington University in St. LouisStereotypic, rigidly scripted behavior is found in cultural rituals, in children’s routines, in obsessive-compulsive disorder, in normal adults around certain stages of the life-cycle. We propose an explanation in terms of an evolved Precaution System geared to the detection of and reaction to inferred threats to fitness, distinct from systemsfor manifest danger. The Precaution system includes a repertoire of potential hazards as well as a repertoire of species-typical precautions. Impairment in the system’s feed-back accounts for OCD rituals. Gradual calibration of this system occurs through childhood routines. Mimicry of this system’s natural input makes cultural rituals salient andcompelling.

With commentary from CS Alcorta & R Sosis; R-P Behrendt; O Benga & I Benga; D Eilam; DMT Fessler; J Foss; JH Hageman; JD Huppert & SP Cahill; RC Jackson &RSW Masters; R Kirov; RN McCauley; B Merker; JL Orrock; I Pyysiainen; A Rothenberger, V Roessner & T Banaschewski; MD Rutherford; G Saad; LD Schipper, JA Easton & TK Shackelford; JE Swain; J Tooby & L Cosmides; R Turner; H Wang & P Bello; EZ Woody & H Szechtman

Is tenure justified? An experimental study of faculty beliefs abouttenure, promotion, and academic freedomStephen J. Ceci, Cornell University, Wendy M. Williams, Cornell University,Katrin Mueller-Johnson, University of CambridgeFaculty members of all ranks were asked how colleagues of all ranks would respond when confronted with dilemmas concerning the exercise of academic freedom. Fullprofessors were perceived to be more likely to insist on academic freedom to teach unpopular courses, research controversial topics, and whistle-blow ethical wrong-doingthan were lower-ranked professors, including tenured associate professors. Everyone thought that others were more likely to exercise academic freedom than they them-selves were and that promotion to full professor was a better predictor of who would exercise academic freedom than was the awarding of tenure. These findings chal-lenge the assumption that tenure can be justified because it fosters academic freedom.

With commentary from L Bennich-Bjorkman; JL Buck; HL Carmichael; JM Clark; E Donchin; DC Donderi; F Farley; JR Flynn; EA Franz & H Hayne; S Fuller; G Greenberg & DK Billings; AJ Jacobson; SO Lilienfeld; K MacDonald; WB MacLeod; D Peters; J Ruscio & A Kelly-Woessner; M Shermer; J Wettersten

Among the articles to appear in forthcoming issues of BBS:

P. Boyer & P. Lienard, “Why ritualized behavior? Precaution systems and action parsing in developmental, pathological and cultural rituals” http://www.bbsonline.org/Preprints/Boyer-04042005/Referees

S. J. Ceci, W. M. Williams & K. Mueller-Johnson, “Is tenure justified? An experimental study of faculty beliefs about tenure, promotion, and academic freedom” http://www.bbsonline.org/Preprints/Ceci-04182005/Referees/

H. Gintis, "A framework for the unification the behavioral sciences" http://www.bbsonline.org/Preprints/Gintis-12052005/RefereesB. Merker, “Consciousness without a cerebral cortex:

A challenge for neuroscience and medicine" http://www.bbsonline.org/Preprints/Merker-03062006/RefereesH. C. Dijkerman & E.H.F. de Haan, “Somatosensory processes

subserving perception and action” http://www.bbsonline.org/Preprints/Gintis-01052006/RefereesR. E. Jung & R. J. Haier, “The Parieto-Frontal Integration Theory (P-FIT) of

intelligence: Converging neuroimaging evidence” http://www.bbsonline.org/Preprints/Jung-10182005/Referees

VOLUME 29NUMBER 5OCTOBER 2006

ISSN 0140-525X

Appearing in this issue, with Commentary . . .

The folk psychology of soulsJessie M. Bering

The unified theory of repressionMatthew H. Erdelyi

An International Journal of Current Researchand Theory with Open Peer Commentary

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Cambridge Journals OnlineFor further information about this journal please go to the journal website at:http://www.journals.cambridge.org/jid_bbs

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