neurodegeneration antibodies - cedarlane over 135 antibodies targeting more than 310...
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Neurodegeneration AntibodiesOver 135 Antibodies Targeting More Than 310 Neurodegeneration Proteins
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NeurodegenerationBelow is a sampling of select antibodies targeting proteins for neurodegeneration research. For a complete product listing, please visit: http://www.bethyl.com/category/pca_research_NEUROBIOLOGY.
Target Reactivities Applications # of Abs AbVantage™ Pack
ALS2 / Alsin NEW Hu, Ms WB 1
AP2A1 / Alpha-adaptin NEW Hu WB, IP 1
AP2B1 / Beta-2-adaptin NEW Hu, Ms WB, IP 2 Yes
APTX / Aprataxin Hu WB, IP 1
ATF6 Hu WB, IP, IF, IHC 2 Yes
ATM Hu, Ms WB, IP, IF, IHC, PLA 6 Yes
ATP2A2 / SERCA2 Hu, Rt, Pg, Rb WB, IP 1
ATXN2 / ATX2 / SCA2 Hu, Ms WB, IP 1
BID* Hu, Ms WB, IF, IHC 6 Yes
CHMP2B NEW Hu, Ms WB, IP, IF, IHC 2 Yes
CREB1 / CREB Hu, Ms WB, IP, IF, IHC, PLA 2
CREBBP / CBP Hu WB, IP, IF, IHC, PLA 3 Yes
CTNNB1 / beta-catenin Hu, Ms WB, IP, IF, IHC, PLA 4 Yes
CUL1 Hu, Ms WB, IP, IF, IHC, PLA 2 Yes
DYNC1H1 NEW Hu, Ms WB, IP 1
EIF4G1 / eIF4GI Hu, Ms, Rt WB, IP, IF, IHC 5 Yes
EP300 / p300 HuWB, IP, IF, IHC, ChIP-Seq,
PLA3 Yes
EPRS Hu, Ms WB, IP, IF, IHC 3 Yes
ESR1 / Estrogen Receptor
Alpha*Hu WB, IP, IF, IHC, PLA 5 Yes
FBXW7 / FBW7 Hu IP, IF, IHC 3 Yes
FLVCR1 NEW Hu WB, IP 1
FUS Hu, Ms WB, IP, IF, IHC, PLA 6 Yes
GAPDH Hu, Ms, Rt WB, IF, IHC, PLA 9 Yes
GIGYF2 Hu WB, IP 2 Yes
GSK3B / GSK3-beta Hu, Ms WB, IP, PLA 2 Yes
HDAC1 Hu, Ms WB, IP, IF, IHC, PLA 3 Yes
HDAC2 Hu, Ms WB, IP, IF, IHC, ChIP-Seq 3 Yes
Detection of mouse eIF4G1 in teratoma by
immunohistochemistry. Antibody: Rabbit
anti-eIF4G1/eIF4GI IHC Antibody, Cat#
IHC-00566.
Detection of human and mouse FUS by
western blot of HeLa, Jurkat, and TCMK
cell lysates. Antibody: Rabbit anti-FUS
Antibody, Cat# A300-302A.
About Bethyl Laboratories
Bethyl Laboratories, Inc. is dedicated to improving lives by supporting scientific discovery through its qualified antibody products and custom antibody services. Since its founding in
1972, Bethyl has manufactured all of its antibodies on-site in Texas to exacting standards with validation to a range of
applications.
Select Journal Citations
Target Title Journal
ATM RSF1 Histone-Remodelling Factor Facilitates DNA Double-Strand
Break Repair by Recruiting Centromeric and Fanconi Anaemia
Proteins.
PLoS Biol. 2014 May
6;12(5):e1001856.
BICD2 Distinct Sets of Rab6 Effectors Contribute to ZW10- and COG-
Dependent Golgi Homeostasis.
Traffic. 2014 Feb 27.
FUS Progressive Supranuclear Palsy in a family with TDP-43 pathology. Neurocase. 2014 Jan 30.
FUS Potentiated Hsp104 variants suppress toxicity of diverse
neurodegenerative disease-linked proteins.
Dis Model Mech.
2014 Jul 25. pii:
dmm.016113.
TMEM106B TMEM106B, the Risk Gene for Frontotemporal Dementia, Is
Regulated by the microRNA-132/212 Cluster and Affects
Progranulin Pathways.
J Neurosci. 2012 Aug
15;32(33):11213-27.
All antibodies are antigen affinity purified.*Phospho-specific available
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Antibodies
Target Reactivities Applications # of Abs AbVantage™ Pack
HK1 / Hexokinase 1 NEW Hu, Ms WB 1
HSPB1 / HSP27 NEW Hu WB, IP 2 Yes
KIF1B Hu, Ms WB, IP 2 Yes
KIF5A NEW Hu WB, IP 1
MAPK14 / p38 MAPK Hu, Ms WB, IP 2 Yes
MTMR2 NEW Hu, Ms WB 1
NCSTN / Nicastrin NEW Hu WB, IP 1
NOTCH1 Hu WB, IP, IF, IHC, PLA 3 Yes
OPTN / Optineurin Hu WB, IP 2 Yes
POLR2A / RNA
Polymerase II* NEWHu, Ms WB, IP, IF, IHC, ChIP-PCR, PLA 9 Yes
POLR2B / Rpb2 Hu WB, IP 2 Yes
PPARG /PPAR-gamma NEW Hu, Ms WB, IP 2 Yes
PPARGC1A / PGC-1 Hu IF, IHC 1
PPP2R5D Hu, Ms WB, IP 3 Yes
PPP3CA Hu, Ms WB, IP, IF, IHC 3 Yes
PPP5C Hu, Ms WB, IP, IF, IHC, PLA 2
PSEN2 / Presenilin-2 NEW Hu WB, IP, IF, IHC 1
PSMC5 / TRIP1 / SUG1 Hu, Ms WB, IP, IF, IHC 3 Yes
PSMD11 Hu, Ms WB, IP 2 Yes
PTGS2 / COX-2 Hu WB, IP, IF, IHC 1
RCOR1 / CoREST Hu WB, IF, IHC, PLA 2
REST Hu WB, IP, IF, IHC 3 Yes
SETX / Senataxin Hu WB, IP 2 Yes
SIN3A Hu, Ms WB, IP, IF, IHC 3 Yes
SOD2 / MnSOD Rt WB 2 Yes
SP1 Hu, Ms WB, IP, IF, IHC, PLA 4 Yes
SPTBN2 / SCA5 Hu WB, IP 2 Yes
Detection of human TDP1 by western
blot of immunoprecipitates from HeLa
cell lysate. Antibodies: Rabbit anti-TDP1
Antibody, Cat# A301-618A, used for
immunoprecipitation and western blotting.
TDP1 was also immunoprecipitated by
A301-619A, which recognizes a different
epitope.
Detection of human eEF2 in colon
carcinoma by immunofluorescence.
Antibody: Rabbit anti-eEF2 IHC Antibody,
Cat# IHC-00330.
Detection of human Optineurin by western
blot of immunoprecipitates from HeLa cell
lysate. Antibodies: Rabbit anti-Optineurin
Antibody, Cat# A301-831A, used for
immunoprecipitation and western blotting.
Optineurin was also immunoprecipitated
by A301-829A, which recognizes a
different epitope.
All antibodies are antigen affinity purified.*Phospho-specific available
Select Journal Citations
Target Title Journal
APTX /
Aprataxin
Genotype-phenotype correlations in early onset ataxia with ocular
motor apraxia and hypoalbuminaemia.
Brain. 2011 May;134(Pt
5):1387-99.
TARDBP /
TDP43
Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS
Patients with TDP-43 Mutations.
PLoS One. 2013 Oct
15;8(10):e76055.
TMEM106B TMEM106B expression is reduced in Alzheimer's disease brains. Alzheimers Res Ther.
2014 Mar 31;6(2):17.
VCP Ubiquitin ligase human TRIM71 regulates let-7 microRNA
biogenesis via modulation of Lin28B protein.
Biochim Biophys Acta.
2014 Mar 3. pii: S1874-
9399(14)00045-5.
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Neurodegeneration AntibodiesBelow is a sampling of select antibodies targeting proteins for neurodegeneration research. For a complete product listing, please visit: http://www.bethyl.com/category/pca_research_NEUROBIOLOGY.
Target Reactivities Applications # of Abs AbVantage™ Pack
STUB1 / CHIP Hu, Ms WB, IP, IF, IHC, PLA 3 Yes
TAF1 Hu WB, IP, IF, IHC 2 Yes
TBP Hu WB 1
TDP1 Hu WB, IP, IF, IHC, PLA 3 Yes
TFG Hu, Ms WB, IP 3 Yes
TMEM106B Hu, Ms WB 1
TP53 / p53 Hu WB, IP, IF, IHC, F, PLA 4 Yes
UBA1 / UBE1 Hu, Ms WB, IP, IF, IHC 5 Yes
VAPB Hu, Ms WB, IP, IF, IHC 1
VCP Hu, Ms WB, IP, IF, IHC, PLA 3 Yes
VPS35 NEW Hu, Ms WB, IP 1
Detection of human FUS by western blot of
immunoprecipitates from HeLa cell lysate.
Antibodies: Rabbit anti-FUS Antibody, Cat#
A300-302A, used for immunoprecipitation
and western blotting. FUS was also
immunoprecipitated by a previous lot of
this antibody.
Detection of human PSMD1 in breast
carcinoma by immunohistochemistry.
Antibody: Rabbit anti-PSMD1 Antibody,
Cat# A303-852A.
All antibodies are antigen affinity purified.*Phospho-specific available
Select Journal Citations
Target Title Journal
DAXX Alternative lengthening of telomeres in neuroblastoma cell lines is
associated with a lack of MYCN genomic amplification and with p53
pathway aberrations.
J Neurooncol. 2014
May 3.
GAPDH LPS-induced microglial secretion of TNFa increases activity-
dependent neuronal apoptosis in the neonatalcerebral cortex.
Cereb Cortex. 2013
Jul;23(7):1742-55.
KIF1B Dynamic changes in presynaptic and axonal transport proteins
combined with striatal neuroinflammation precede dopaminergic
neuronal loss in a rat model of AAV alpha-synucleinopathy.
J Neurosci. 2009 Mar
18;29(11):3365-73.
Bethyl Laboratories, Inc. now offers over 3,500 trial-sized antibodies to more than 2,200 protein targets. Since its founding in 1972, Bethyl has manufactured all of its antibodies on-site in Texas to exacting standards with validation to a range of applications.
Trial sizes are conveniently priced and serve as an opportunity to discover for yourself why our antibodies are really good.
Bethyl will be releasing hundreds more trial-sized antibodies in the upcoming months.
Terms & Conditions: See website for US pricing; international customers please contact your distributor for details. Trial-sizes (catalog # ending in “-T”) are not available for all antibodies and existing promotions or discounts do not apply.
Please visit www.bethyl.com/trialsize for a complete list of proteins targets available as a trial size.
Now Available Trial-Size Antibodies!
Detection of human CD44 in
lung carcinoma by immunofluorescence.
Antibodies: Rabbit anti-CD44 Antibody,
Cat# A303-872A. Secondary: Goat
anti-Rabbit IgG (H+L) Antibody, DyLight®
550 Conjugated, Cat# A120-101D3.