nerve and muscle physiology · 2020-02-03 · _55 -70 depolarizing phase epolarizing phase stimulus...

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Nerve and Muscle Physiology Plasma Membranes of Excitable tissues Ref: Guyton, 13 th ed: pp: 61-71. 12 th ed: pp: 57-69. 11th ed: p57-71,

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Page 1: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization

Nerve and Muscle

Physiology

Plasma Membranes of Excitable

tissues

Ref: Guyton, 13th ed: pp: 61-71. 12th ed:

pp: 57-69. 11th ed: p57-71,

Page 2: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 3: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization

Fig. 12.09a,b

Page 4: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization

Nernest equation

Page 5: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization

Ek+

E (mV) = - 61.log (Ci/Co)

E = Equilibrium potential for a univalent ion

Ci = conc. inside the cell.

Co = conc. outside the cell.

Page 6: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization

Goldman Hodgkin Katz

equation

i = Conc. inside

o = Conc. outside

P = permeability of the membrane to that ion.

Page 7: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 8: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 9: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 10: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 11: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 12: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 13: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 14: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 15: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 16: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 17: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 18: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 19: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 20: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 21: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization
Page 22: Nerve and Muscle Physiology · 2020-02-03 · _55 -70 Depolarizing phase epolarizing phase Stimulus After-hyperpolarizing phase Time in milliseconds (msec) Key : Reversal of polarization