3D Printing in Medicine and Nephrology

Dr Ashutosh OjhaMBBS,MD,PDC(Nephrology)

MRCP(UK)I,FACP(USA)

Plan • Need • Aging and senescence • Organ dysfunction quantum• Organ sources ..cells in abundance• Methods to regenerate..an organ• Necessary ingredients• Organ reconstruction methods and challenges• Engineered organs care and longevity • Limitation• Recent Advances

Need

Need ….

Mech …Aging

Mech …Aging

Prevention of Aging

Cell conditioning

Advantages

• Small amount of own tissue used• Mostly harvestable sites• No antigenicity • No ethical issue

Disadvantages

• Organs with good and perennial nutrition available only can be used

• Scafolds needs to be bio-inert ….big challenge• Once transplanted the many organs age very

fast….compared to non organic ones• Metallic Heart valves last thrice the

bioprosthetic • Process time……6 months

Wayout….

• Tissue banking• Cytokines …..prepared by DNA recombinant

tech• Nutrient media research• Incubators • Sonicators • Fluroscopic analysis of media

Wayout….2..

• CAD scaffold designing • Tissue orientation • Scaffold repositioning • Tissue scavengers and enhancers

• ….commitment of you and me

There is a great hope of control of all neurodegenerative disorder……….85% of the age

related morbidity

Thank You• My slides are open …available