nature genetics, supplement, november 2004

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ature Genetics, Supplement, November 2004

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Nature Genetics, Supplement, November 2004. http://anthro.palomar.edu/vary/vary_3.htm. Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27. Out of Africa Theory: Greater Genetic Diversity in Africa: Greater Heterozygosity. - PowerPoint PPT Presentation

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Page 1: Nature Genetics, Supplement, November 2004

Nature Genetics, Supplement, November 2004

Page 2: Nature Genetics, Supplement, November 2004
Page 3: Nature Genetics, Supplement, November 2004
Page 4: Nature Genetics, Supplement, November 2004

http://anthro.palomar.edu/vary/vary_3.htm

Skin Color:Adaptation to equitorial environment

Page 5: Nature Genetics, Supplement, November 2004

Cavalli-Sforza et al. (1994) The hisgtory and geography of human genes.

Human populations blend:Genetically, you look like your neighbors

Page 6: Nature Genetics, Supplement, November 2004

Principal components analysis of population structure in 554 individuals.

Xing J et al. Genome Res. 2009;19:815-825

Copyright © 2009 by Cold Spring Harbor Laboratory Press

Page 7: Nature Genetics, Supplement, November 2004

Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27

Page 8: Nature Genetics, Supplement, November 2004

Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27

Out of Africa Theory:Greater Genetic Diversity in Africa:

Greater Heterozygosity

Page 9: Nature Genetics, Supplement, November 2004

Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27

Out of Africa Theory:Greater Genetic Diversity in Africa:

Less Linkage Disequilibrium

Page 10: Nature Genetics, Supplement, November 2004

http://anthro.palomar.edu/vary/vary_3.htm

Page 11: Nature Genetics, Supplement, November 2004

http://anthro.palomar.edu/vary/vary_1.htm

Clinal Distribution Discontinuous Distribution

Hair Color

Page 12: Nature Genetics, Supplement, November 2004
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Between 85% and 95% of allgenetic variation exists within a

continental population.

Implications: asteroid

Page 21: Nature Genetics, Supplement, November 2004

HGSS: Carey: Figure 14.1

Page 22: Nature Genetics, Supplement, November 2004