n104 01 alteration in perception and coordination

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    Luisito P. Yolangco, RN.DVM.MAN.

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    CONTROL CENTER &COMMUNICATION

    NETWORK of the body Works hand in hand with ENDOCRINE

    system to regulate and maintain

    homeostasis

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    HOW IT WORKS?

    Directs the functionsof the bodys organsand systems

    Uses rapid & specific electrical impulsesas signaling devices

    Allows us to interpret and respond to the

    changes in the external environment Thoughts, actions & emotions reflect its

    activity

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    Sensory Reception(Receptors)

    Motor Response(Effector)

    INTEGRATION

    INPUT

    OUTPUT

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    NERVOUSSYSTEM

    CNS PNS

    Brain Spinal Cord 12 CNs 31 SNs

    Somatic Autonomic

    SNS PSNS

    ORGANIZATIONOF THE

    NERVOUS SYSTEM

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    One of the largestorgans of the body

    Weights about 3 lbs Protected by cranial

    bones and themeningesDM,

    AM, PM

    Contains CSF

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    CEREBRUM

    MIDBRAIN

    MEDULLA OBLONGATA

    PONS CEREBELLUM

    MIDBRAIN

    THALAMUS

    HYPOTHALAMUS

    DIENCEPHALON

    BRAINSTEM

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    Neurotransmitter

    -communicate messages from one neuron toanother or from a neuron to a specific targettissue.

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    Neurotransmitters

    Acetylcholine major transmitter of the PNSusually excitatory in CNS and NMJ

    Inhibitory or excitatory in ANS

    Gamma-aminobutyric acid (GABA) - inhibitory

    Enkephalin, endorphin excitatory, pleasurablesensation, inhibits pain transmission

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    CSF Characteristics

    Clear & colorless

    Sp. Gr. = 1.007

    Approx. 150 ml ( 15-25 ml in each ventricle) Contains:

    Albumin 15-30 mg.dl

    Glucose 50-75 mg.dl

    Glutamine 6-15mg/dl IgG 0-6.6 mg/dl

    WBC 0-5 per mm3

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    T EPERIPHER L NERV USYSTEM

    1. Sensory-Somatic

    a. Cranial Nerves

    b. Spinal Nerves

    a. Parasympathetic

    b. Sympathetic

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    PNS

    Consists ofNERVES, CELL BODIES &PROCESSESoutside the CNS

    1. sensory-somatic

    2.autonomicnervous system

    CN

    SN

    SNSPSNS

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    Cranial Nerves

    Sensory-Somatic Nervous System

    pairs of CNs Primarily innervate the

    except

    for which extendsto the thorax &abdomen

    Functions:

    ensoryotor (Somatic)arasympathetic

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    I. OlfactoryII. OpticIII. OculomotorIV. TrochlearV. Trigeminal*VI. AbducensVII. FacialVIII. Acoustic/

    Vestibulocochlear

    IX. GlossopharyngealX. VagusXI. Accessory/SpinalXII. Hypoglossal

    Note: * S,M only

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    Olfactory Optic Oculomotor

    Trochlear

    AbducensTrigeminal

    Facial

    Acoustic/Vestibulocochlear

    Glossopharyngeal

    Vagus

    Accessory/SpinalHypoglossal

    Some Say MarryMoney But My Brother

    Says Big Business

    Makes Money.

    Still can'tremember thenames of thecranial nerves?

    Name FunctionType#

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    Tongue movementMHypoglossalXII

    Accessory

    Vagus

    Glossopharyngeal

    Acoustic

    Facial

    Abducens

    Trigeminal

    Trochlear

    Oculomotor

    Optic

    Olfactory

    Name

    Head & shoulder movementMXI

    swallowing; digestive,respiratory, cardiovascularactivities

    BX

    taste; swallowing; tongue movement; salivationBIX

    hearing & balanceSVIII

    taste;saliva & tears production; facial expressionBVII

    lateral eye movementMVI

    sensation from the face & mouth; masticationBV

    upward & downward eye movementMIV

    extraocular eye movement;pupillary reactionMIII

    visionSII

    smellSI

    FunctionType#

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    Spinal Nerves

    Sensory-Somatic Nervous System

    pairs of SNs Formed by dorsal &

    ventral roots of the spinalcord

    Divided into dorsal &ventral rami whichcontain both motor &sensory fibers

    Named according tosegment of spinal cord

    they are attached.

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    Nerve Plexuses

    Complex networks of nerves

    Serve the motor and sensory needs ofthe extremities

    Classified into (4):

    Cervical

    Brachial Lumbar

    Sacral

    http://www.loweychiropractic.com/neuropathophysiology-1sm.jpg
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    Cervical PlexusC1 C5

    Brachial PlexusC6 C8; T1

    Lumbar PlexusL1 L4

    Sacral PlexusL4 L5; S1-S4

    neck, shoulder & diaphragm phrenic nerve

    lower abdomen, buttocks,anterior/ medial thigh, medialleg & hip

    femoral & obturator nerve

    upper extremity- shoulder,forearm, wrist & hand

    axillary, radial, median,musculocutaneous, & ulnar

    lower trunk, posterior thigh &lateral and posterior leg, foot,buttocks & external genitalia

    sciatic (peroneal & tibial),pudendal nerve

    PLEXUSESRegions supplied/Major nerves

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    SNSPSNS

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    A utomatically & continuously functionsU nder involuntary controlT wo neurons between CNS & effector organsO ne stimulates and the other inhibitsN eurotransmitters cholinergic & adrenergicO pposite effects on the same organs

    M otor impulses

    I nnervates smooth & cardiac muscles and glandsC oncerned with vital signs & other visceral activities

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    NEUROLOGICASSESSMENT

    NVS

    Neurovital Signs

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    NEUROLOGIC ASSESSMENT

    Neurologic Examination Mental Status

    Sensation

    Cranial Nerves

    Motor Function

    Reflexes

    COMPOSURE quick neurological

    assessment..

    C i

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    LOC

    Verbal Tactile Pain

    Conscious (+) (+) (+)

    Lethargic (+) (+) (+) *Stuporous (-) (-) (+)

    Comatose (-) (-) (-)

    FORMS OF

    STIMULI

    VERBAL

    VOICE

    SHOUT

    TACTILE

    TOUCH

    TAP/ SHAKE

    PAIN

    SUPERFICIAL

    DEEP

    Consciousness

    * delayed reaction

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    Pain Stimulus

    IMPLICATION: Consciousness

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    1st & MOST sensitive indicator

    of neurologic change

    IMPLICATION: Consciousness

    GLASGOW COMA SCALE

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    GLASGOW COMA SCALE Description

    Spontaneously To Speech

    To Pain

    Do not Open

    Oriented

    Confused

    InappropriateSpeech

    Unintelligible speech

    No verbalization

    Obeys Command

    Localizes Pain

    Withdraws from pain Abnormal Flexion

    Abnormal Extension

    No Motor Response

    Subscale

    EYE OPENING

    (E)

    VERBALRESPONSE

    (V)

    MOTORRESPONSE

    (M)

    Score

    4 3

    2

    1

    5

    4

    3

    2

    1

    6 5

    4

    3

    2

    1

    *

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    Oxygenation

    Assess respiratory status.

    Resp rate, rhythm

    Auscultate breath sounds/ air entry.

    Maintain patent airway & adequateventilation.

    O2 therapy, Mechanical Ventilation

    Monitor for S/S of cardiorespiratorydistress

    Note for S/S of Hypoxia/ hypoxemia

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    Motor Function

    Assess integration of consciousness& voluntary movement.

    Look for purposeful or non-purposeful response.

    Assess muscle tone, size, strength.

    Observe for symmetric, spontaneousmovement of arms & legs

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    IMPLICATION: Motor Function

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    Assessment tool Motor Function

    2 5

    51

    15

    42

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    Pupils

    Assess for size, shape &reaction to light.

    Observe for ptosis.

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    Ocular Movement

    Assess for deviationto one side.

    Also assess voluntary

    & spontaneousmovement

    III, IV, VI

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    Signs

    Assess V/S.

    Observe for significant trends.

    Look for Cushings reflex:

    PR,

    RR,

    Widened Pulse Pressure

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    Urinary Output

    Assess for increased output,possible S/S of impaired waterregulation.

    Also assess for electrolyteimbalance

    Oliguria = ( below 30 cc)

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    Reflexes

    Assess for pathologic reflexes,

    especially babinski & loss ofcorneal or gag reflex

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    controlled by L4 & L5, S1 & S2

    N=toe flexion (except in infant)Abn=Dorsiflexion of big Toe,Fanning of Little Toes (exceptin infant) Pyramidal Tract /Upper Motor Neuron Damage

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    Biceps, Triceps, Patellar, Achilles,Brachioradialis

    DTR GRADING

    DTR GRADE Response

    0 Absent reflex

    1+ Diminished

    2+ Normal

    3+ Slightly increased

    4+ Hyperactive

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    Emergency

    Evaluate assessment findingsto determine whetheremergency exists.

    If so report findings to doctor

    STAT

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    Ask client to SNIFF &identify aromatic

    substances.

    CN I : OLFACTORY

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    Use of Snellen Chart

    Ask client to readprinted materials

    CN II : OPTIC

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    Assess directions ofgaze by asking client tofollow moving objects.

    Measure pupillaryreaction to light reflex& accommodation

    CN III : OCULOMOTOR

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    Assess directionsof gaze by askingclient to follow

    moving objects.

    CN IV & VI: TROCHLEAR

    and ABDUCENS

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    Corneal reflex Assess light touch & pain

    sensation across theface

    Opening the mouthagainst resistance &moving the jaw from theside to side

    CN V : TRIGEMINAL

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    CN VII : FACIAL

    Ask client to smile,whistle, frown, puff outcheeks, & moveeyebrows

    Have client identifysalty & sweet tastes onfront of the tongue

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    CN VIII : ACOUSTIC

    Air & bone conduction Ability to hear spoken

    word

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    CN IX : GLOSSOPHARYNGEAL Ask client to identify

    sour, salty or sweettastes on back of thetongue

    Elicit gag reflex and

    assess swallowingreflex.

    Ask to speak or cough.

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    CN X : VAGUS

    Ask client to say ahand assess formovement of thepalate and pharynx

    Elicit gag reflex Ask client to speak.

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    CN XI : ACCESSORY

    Ask client toSHRUG shoulders& turn head

    against resistance

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    CN XII : HYPOGLOSSAL

    Ask client to stick outtongue and move it

    from side to side

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    DIAGNOSTIC

    EVALUATION

    1 C d T h S i

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    1.Computed Tomography Scanning(CTScan)

    2.Positron Emission Tomography (PET)3.Single Photon Emission Computed

    Tomography (SPECT)4.Magnetic Resonance Imaging (MRI)

    5.Cerebral Angiography6.Myelography7.Noninvasive Carotid Flow Studies8.Transcranial Doppler

    9.Electroencephalography (EEG)10.Electromyography (EMG)11.Evoked Potential Studies12.Lumbar Puncture and Examination

    of CSF

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    Computed Tomography Scanning

    -Makes use of a narrow x-ray beam to scan thebody part in successive layers.-Can be performed first without contract followedwith contrast.

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    Positron Emission Tomography

    --A computer-based nuclear imaging techniquethat produces images of actual organ functioning.-Permits the measurement of blood flow, tissuecomposition and brain metabolism

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    Single Photon Emission ComputedTomography

    -A three-dimensional imaging technique thatuses radio-nuclides and instruments to detectsingle photons.-A perfusion study that captures a moment of

    cerebral blood flow.

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    Magnetic Resonance Imaging

    -Uses a powerful magnetic field to obtain

    images of different areas of the body.-Can be performed with or without contrast-Provides information about the chemicalchanges within the cells

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    Cerebral Angiography

    -An X-ray study of the cerebral circulation witha contrast agent injected into a selected artery.

    -Performed by threading a catheter through thefemoral artery in the groin and up to thedesired vessel.

    M l h

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    Myelography

    -An xray of the spinal subarachnoid space

    taken after the injection of a contrast agent intothe spinal subarachnoid space through alumbar puncture.-Outlines the subarachnoid space and showsany distortion of the spinal cord or spinal dural

    sac

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    Noninvasive Carotid Flow Studies

    -Use ultrasound imagery and dopplermeasurements of arterial blood flow toevaluate carotid and deep orbital circulation.

    Transcranial Doppler

    -Uses the same noninvasive techniques ascarotid flow studies except that it records theblood flow velocities of the intracranial vessels.

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    Electroencephalography

    -Represents a record of the electrical activitygenerated in the brain.

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    Electromyography

    -Is obtained by inserting needle electrodes intothe skeletal muscles to measure changes inthe electrical potential of the muscles and thenerves leading to them.

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    Evoked Potential Studies

    -These studies are based on the concept that

    any insult or dysfunction that can alterneuronal metabolism or disturb membranefunction may change evoked responses inbrain waves.

    L b P d E i i

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    Lumbar Puncture and Examinationof CSF

    -Queckenstedts test: lumbar manometric test-Check for post-lumbar headache and othercomplications of lumbar puncture.

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    lpy