mycotoxins phycotoxins

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CURRICULUM VITAE Name: Prof. Dr. Khayria Mahmoud Naguib. Nationality: Egyptian. Present position: Professor, of Food Toxins and Contaminants Department, Food Toxins and Contaminants Department., National Research Center, Dokki, Cairo, Egypt. Scientific Environmental Achievement o During the period from 1956 until 1976, I was working in the field of Food & Dairy Microbiology where I had developed and was the leader of this branch of research at the National Research Center (NRC). I was the head of the Food & Dairy Microbiology unit from 1966 to 1976. o The second period of my environmental research extended between 1976 2006. In 1976, I have introduced-and for-the first time in Egypt and the Afro-Asian countries- a new area of research dealing with the environmental toxicology mainly: "Mycotoxins". Ten years later, in 1986, I introduced the "Phycotoxins" research in Egypt and the Afro- Asian countries as well. o In 1986, I established the Mycotoxins and Food Safety Central Lab "MFSCL" in NRC which considers the first lab in Egypt and the Afro-Asian countries that deals with the food toxins and/or contaminants and is considered as well as the reference lab for all the governmental and private sectors. This lab extended the knowledge to the staff in Universities and Research Centers and other concerned National and International Agencies in Egypt and Afro-Asian countries through the National and/or International training courses and workshops continuously held in Egypt covering the following areas: Mycotoxins, Phycotoxoins and other food contaminants as Pesticides, Heavy metals and amines. It was and still acts as an open university for specialized concerned stuff in Egypt and the surrounding Afro-Asian countries. Moreover, "MFSCL" acts as judging lab for different concerned agencies. o I supervised 66 M.Sc. and Ph.D. Theses awarded during this period and published 115 research papers in the aforementioned areas. With this experience, I am an arbitrator in any disputes in food contaminants. The following phases summarize my achievement in environmental research:

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Page 1: Mycotoxins Phycotoxins

CURRICULUM VITAE

Name: Prof. Dr. Khayria Mahmoud Naguib.

Nationality: Egyptian.

Present position: Professor, of Food Toxins and Contaminants Department,

Food Toxins and Contaminants Department., National Research Center, Dokki,

Cairo, Egypt.

Scientific Environmental Achievement

o During the period from 1956 until 1976, I was working in the field of Food &

Dairy Microbiology where I had developed and was the leader of this branch

of research at the National Research Center (NRC). I was the head of the Food

& Dairy Microbiology unit from 1966 to 1976.

o The second period of my environmental research extended between 1976 –

2006. In 1976, I have introduced-and for-the first time in Egypt and the

Afro-Asian countries- a new area of research dealing with the

environmental toxicology mainly: "Mycotoxins". Ten years later, in

1986, I introduced the "Phycotoxins" research in Egypt and the Afro-

Asian countries as well.

o In 1986, I established the Mycotoxins and Food Safety Central Lab "MFSCL"

in NRC which considers the first lab in Egypt and the Afro-Asian countries

that deals with the food toxins and/or contaminants and is considered as well

as the reference lab for all the governmental and private sectors. This lab

extended the knowledge to the staff in Universities and Research Centers and

other concerned National and International Agencies in Egypt and Afro-Asian

countries through the National and/or International training courses and

workshops continuously held in Egypt covering the following areas:

Mycotoxins, Phycotoxoins and other food contaminants as Pesticides, Heavy

metals and amines. It was and still acts as an open university for specialized

concerned stuff in Egypt and the surrounding Afro-Asian countries. Moreover,

"MFSCL" acts as judging lab for different concerned agencies.

o I supervised 66 M.Sc. and Ph.D. Theses awarded during this period and

published 115 research papers in the aforementioned areas. With this

experience, I am an arbitrator in any disputes in food contaminants.

The following phases summarize my achievement in environmental research:

Page 2: Mycotoxins Phycotoxins

Phase I

o Research achievements during this period were devoted to monitor and

measure microbial contamination in Food & Dairy Products. I was the leader

of the groups who began the first scientific survey for the occurrence of

different health hazards including the pathogenic microorganisms in varies

Egyptian food products which include coliforms, aerobic and anaerobic

sporeformers coagulase-positive Staphylococci, Salmonella and Shigellae

microorganism. Furthermore, I investigated and strengthened my research

activities towards new food-borne pathogens (Campylobacter geguini, Enter

pathogenic Escherichia coli, Yersinia enterocolitica, Listeria monocytogenes).

This enabled the understanding of preventive actions to overcome such

environmental food hazard to the consumers. Due to the wide contamination

of Egyptian foods with pathogenic microorganisms, the research was extended

to determine the survival rates of such organisms in the products. In addition,

factors enhancing the rapid destruction of such microorganisms were

considered.

o Special attention was given to the studies of staphylococcal food poisoning.

The research in this area was developed in 1964 through the experience I got

during my post-doctor fellowship in Germany funded by the Alexander Von

Hamboldt Foundation, along with the aid of this organization in developing

my laboratory with the equipments needed for determining the staphylococcal

enterotoxins.

o In 1966, I successfully conducted a research program to industry to eliminate

microbial contamination in the production of safe food products. I solved the

environmental contaminant problems for different food products, which reflect

in both the public health and economic points of view. I was the first (may be

allover the world) who shed the light on the analyze hazards, identify

critical control points, establish preventive measures with critical limits

for each control point during this program. Such achievements are

recently known as "HACCP" concept (Hazard Analyses and Critical

Control Points) a system of food safety control.

Phases II

In this phase, I concentrated in 1976 my activity for the research on

"Mycotoxins" as a new area for the first time in Egypt and the Afro-Asian

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countries, which have been started and developed in my laboratory through two joint

research projects with the Food and Drug Administration, Washington, funded by the

USAID (USA). The first project started in 1976 for three years, during which a highly

specialized laboratory for mycotoxins analysis was developed, equipped, and as well

provided with highly trained personal. This aided the First National wide sampling

plan intensive survey of aflatoxin residues in Egyptian foods and feeds, through

the project entitled “Aflatoxin residues in Egyptian foods and feeds derived from

plants and animal sources” by the end of this project three reports were presented. The

second project started in 1981 for three years too and dealt with organizing and

directing two International Symposiums & Workshops on MYCOTOXINS in

1981 and 1983.

Through these two International Conferences and Workshops, 307 & 420 participants

representing 38 & 44 countries respectively attended, I was able to promote a better

understanding for mycotoxin problems existing in Afro-Asian countries, educate

and lay the basis as well for developing and establishing effective mycotoxin

control programs with these countries through training and personal scientific

visits. Intensive training programs were conducted in 1981 & 1983 and

representative participants were trained on the determination of mycotoxins in

foods. Several specialized professors from USA, Canada, Europe and Japan presented

the plenary basic lectures which included: The general aspects of food safety, history

and awareness of mycotoxins, limits and regulations, conditions leading to

contamination, prevention and control, metabolism and transmission, screening

procedures, decontamination of mycotoxins in food and feeds, Societies Sponsoring

Mycotoxins and FAO mycotoxins Programs. Other methodology professionals from

different countries demonstrated the workshops and trained the participants on the

important aspects: Sampling techniques, preparation of standards, aflatoxins B1

methodology techniques (TLC, CB, BF). Aflatoxin M1, HPLC, densitomertic and

confirmatory techniques and the immunological methods. Laboratory analysis of food

samples by the workshop attendees applying the given techniques and methods.

It is worthy to report that mycotoxins had serious adverse effects on human

health. Its main toxic effects are carcinogenicity, genotoxicity, tetragencity,

hepatotoxicity, nephrotoxicity and immunosuppression. In this concern, we should

point to FAO estimation in 2003 which, reported that world losses of food crops due

to mycotoxins are in the range of 1000 million tons per year (25 % of the total world

Page 4: Mycotoxins Phycotoxins

crops) at a time when the production of agriculture commodities is barely sustaining

the increase production. A part from the economic problem due to losses in crops

yield and cases of markets by non-tariff barriers due to mycotoxins on human health

and animal wealth ought not to be neglected.

Being unavoidable environmental toxins- as INTERNATIONALLY

recognized- pose a unique challenge to the environment. Thus the emphases on safe

detoxification protocols are urgently needed. Accordingly, I strengthened my

scientific activities towards such vital topics. In 1992, I developed a practical unit for

safe and efficient detoxification of aflatoxins-contaminated corn through the National

Agriculture Research Project (NARP) funded by the USAID. Through these projects I

altered to eliminate the Ammoniation, High-pressure, High Temperature

procedure (HPHT) −which was already applied in some states of the USA and some

European countries− due to its serious adverse effects which was biologically

evaluated and proved. In the same concept, in 2000, I introduced the application of

some local adsorbent materials and plant extracts, which successfully acted as free

radical scavengers and antioxidants, providing protective effects against

mycotoxicosis. I submitted 2 patents in this area. Moreover, some American

pharmaceutical company developed certain products based on our previous

research in this area.

Phase III

In 1986, I introduced the field of PHYCOTOXINS for the first time in

Egypt and the Afro-Asian countries. Research on PHYCOTOXOINS and other

food contaminants "pesticides, heavy metals and biogenic amines" started 1986

through a joint research project “Sea Food Toxins” with the Food and Drug

Administration, Washington, and the New Jersey Marine Science Consortium, USA

and funded by USAID "under the umbrella of the Middle East Program on the

Red Sea". The objective of this project was to assess the magnitude of contamination

in fish, water and sediment with pesticides, heavy metals and biogenic amines in

some fishing area in Egypt. Ciguatera-toxin and PSP toxins produced by algae

grown on fish and shellfish harvesting areas were also studied for the first time

in Egypt and the Middle East. Three reports were presented. The project

achievements were presented during an International Conference entitled

"International Symposium and Workshop on Food Contamination: Mycotoxins and

Phycotoxins". This was held in Cairo 4-15 Nov. 1990. This International Symposium

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covered the main basic topics regarding the phycotoxins, mycotoxins, pesticides and

heavy metals as the industrial chemical contaminants. These topics include:

See food toxins in Review, Recent methods for detecting Sea food toxins,

Immunological studies using Monoclonal antibodies for detection of Low Delta

Marine toxins, Structure, Chemical & Physical properties of Marine Dinoflagellate

Toxins associated with Diarrheic and Paralytic Shellfish Poisoning (DSP & PSP).

Chemistry and Toxicology of Fresh Cyanobacteria (Blue-green algae)- Seafood

Toxins arising from spoilage due to improper storage and handling, Industrial

chemical contaminants in foods, Overview of agriculture chemicals and rural health,

International Regulatory Program of Pesticide Residues. Assessment of human

exposure to chemical contaminants in foods. Dietary intake, levels in food and

estimated intake of cadmium, lead and mercury, Advances in pesticide residues

analyses, Sampling and sample quantization of natural toxicants in foods & feeds.

International coordination and validation of analytical methods. Key elements of food

safety monitoring programs.

Mycotoxins in review, Perspectives on mycotoxin decontamination procedures,

Recent advances in analytical methods for mycotoxins, New mycotoxins of public

health significance, Rational for regulatory program for mycotoxins in human foods

and animal feed, Epidemiological studies related to mycotoxins.

Panel Discussions:

International Regulations and food safety monitoring program; Phycotoxoins,

Mycotoxins, Heavy metals and Pesticides.

Decontamination of mycotoxins management of groundnut aflatoxins problems in

developing countries.

Four hundred participants representing 30 countries attended and were trained on:

Phycotoxins: Marine algae field and Fresh water sampling techniques; collection,

preparation, purification, identification, toxicity testing, and immunological methods.

Mycotoxins: sampling, preparation, determination (HPLC, ELISA reader and TLC

techniques) and the immunological methods for aflatoxins and other mycotoxins.

Toxicity testing: Avian, Mouse and Brine Shrimp acute toxicity, Avian Embryo

toxicity and mutagenicity. Laboratory quality assurance.

It is of interest to report that in this Conference, a new discovery of carcinogenic

mycotoxins (FUMONISIN B1 from corn) was announced for the first time in the

world.

Page 6: Mycotoxins Phycotoxins

During 1993, in an extension to my activity and in cooperation with the

Faculty of Medicine-Ain Shams University (Prof. W. Anwar) and the International

Agency for Research on Cancer (IARC)- France (Prof. C. Wild), I conducted an

International Conferences entitled" First PAN African Environmental Mutagen

Society Meeting: Mycotoxins as mutagens and carcinogens, Jan. 23-26, 1993 Cairo,

Egypt. In this conference, more than 150 participants represented 16 countries

attended and the new trends in this area were presented. Moreover, this Conference

was followed by two International Workshops. Participates were trained on the

"Determination of a new biomarker (AFB1-Albumin adduct) for the early

detection of mycotoxin exposure". The second workshop dealt with

"Determination of mytogenic activity of mycotoxins using cell lines". Both

workshops introduced and transfer -for the first time- the knowledge regarding

the Environmental carcinogens and mutagens in Egypt and surrounding Afro-

Asian Countries.

Phase IV

Research on hyper-saline cyanobacterial activities in the Solar Lake, Sinai,

which started 1995 - 2000, through two joint research projects between Egyptian and

German Ministries for Scientific Research (NRC and Max Blank Institute)on Red Sea

program through two projects entitled: Microbial activities in marine interfaces

controlling sediment-water and particle-water fluxes. Neurotoxins derived from

marine organisms: identification and pharmacological characterization.

Based on the experience given in the fore-mentioned phases along with

the well-established laboratories and team of researchers, I arbitrate the disputes

in food contaminants. Such disputes mainly arised between governmental

laboratories and importers. Likewise, I aid exporters through applying food standards for

exports and imports and provide them with certificates, which indicate the safety of their

products.

It is worthy to report that, I contributed to the strengthening of scientific ties between

scientists in the Middle East and extending the peace concept among nations living in the

area

Scientific Environmental Activities

I. Establishments of Essential Environmental Labs.

1. The Food & Dairy Microbiology Unit (1966), National Research Center, Cairo.

2. In 1986 the first Central Laboratory on Mycotoxins and Food Safety

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"MFSCL" in Egypt and the Afro-Asian countries with the collaboration of the

Food and Drug Administration (FDA), USA. The laboratory was established with

the help of the financial support of the USAID, equipped with all the needed

equipments and provided by efficient and well-trained trainees. This Lab. extends

the experience and scientific services for the researchers in different Universities,

Research Centers and the different concerned agencies in Egypt and the Afro-

Asian Countries through the holding of training workshops in the area of

environmental contaminants. It is considered as an Open University to extend this

knowledge and has well trained stuff who gives the experience to the concerned

governmental and private sectors. One of the major roles of the "MFSCL" Lab is

it

acts as the unique judging lab in different problems concerning food

contaminants

and food safety.

3. The Food Technology Pilot Plant with the financial support of USAID to solve

quality control, and food industry problems.

II. Principal investigator of the following projects:

1- Aflatoxin Residues in Egyptian Foods and Feeds Derived from Plants and

Animal Sources (1976-1981). PL 480 Research Project agreement No. 33-627-

F (Egypt & USA).

2- Sea Food Toxin (1986-1992) through the Cooperative Marine Technology

Program for the Middle East USAID Grant NEB. 1058-9-SS-5192-00 (Egypt

& USA).

3- Studies on Occurrence of Recently Known Pathogenic Bacteria

(Campylobacter geguini, Enteropathogenic Escherichia coli, Yersinia

enterocolitica, Listeria monocytogenes) in the Egyptian Foods and Factors

Inhibiting their Growth in

some Foods. Academy of Scientific Research and Technology, Egypt (1990-1993).

4- National Agriculture Research Project (NARP) “Decontamination of

Mycotoxins in Agriculture Commodities”, USAID, Project No. 66-D-2-7

(1992-1994) (Egypt & USA).

5- Microbial activities in marine interfaces controlling sediment-water and

particle-water fluxes (Egypt & Germany). Red Sea program 1995 till 2002.

6- Neurotoxins derived from marine organisms: identification and

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pharmacological (Egypt & Germany) (Co-principle). Red Sea program 1995

till 2002.

7- Food safety proposed program for imported and exported foods to control

different contaminants project supplied by National Research Center(2008-

2010 ).

8- Cigarette eastern company project. Supplied by Cigarette eastern company, Egypt , 11-2008

till now.

III. International Conferences & Workshops:

Directed and head of the following International Conferences and Workshops on

Mycotoxins and Phycotoxins in Egypt:

1- International Symposium and Workshop on Mycotoxins, Cairo, Egypt, 1981*.

2- International Mycotoxin Conference, Egypt, 1983 (Follow up workshop on

Mycotoxins)*.

3- International Symposium and Workshop on Food Contaminants (Mycotoxins

and Phycotoxins), Egypt, 1990*, **

.

4- First PAN African Environmental mutagen society meeting: Mycotoxins as

Mutagens and Carcinogens, Jan. 23-26 1993, Cairo, Egypt.

IV. National Workshops:

Directing two local workshops held annually at the National Research Center Cairo,

Egypt:

1- Determination of Aflatoxins, Fumonisins, Ochratoxins and Biogenic amines in

Foods, Feeds, Tissues and Biological fluids using HPLC and ELISA

techniques.

2- Determination of Pesticides and Heavy metals in Foods, Feeds, Tissues and

Biological fluids by using Gas Chromatography and Atomic Absorption.

Participants represent the quality Control and Food Safety Agencies in Egypt

and the Surrounding Afro-Asian Countries.

V. Memberships of Scientific Associations: 1. Egyptian Association of Applied Microbiology

2. Egyptian Food Science Association

3. Egyptian Chemical Association

4. Egyptian Society of Natural Toxins

5. Egyptian Society of Toxicology

6. Egyptian Dairy Science Association

7. The Association of Official Analytical Chemists (AOAC)

* Prof. A. E. Pohland: Food & Drug Administration (FDA), Washingoton, USA.

** Prof. Robert B. Abel: Director of International Programs, Stevens Institute of Tehnology, Hoboken, USA.

Page 9: Mycotoxins Phycotoxins

VI. Other Environmental Achievements:

1. Awarded the “Alexander Von Humboldt” Fellowship in 1964-1966

(Germany).

2. Selected in 1983-1988 as vice chairman of the Scientific Committee of the

Association of Analytical Chemistry (AOAC), Washington DC., USA.

3. Selected in 1986 as a member of the Food Chemistry Committee

(Mycotoxins) International Union of Pure and Applied Chemistry (IUPAC),

USA.

4. Selected in 1987 as a chairman of Nutrition and Toxin Committee of the

International Congress of Nutrition in Seoul, Korea, The International Union

of Nutritional Sciences (IUNS).

5. Later on, I awarded the National State Esteem Prize for my achievements

in Environment and Advanced Technological Sciences (2005).

6. Represented Egypt in several International Conferences all over the world as

well as National Conferences.

Thesis supervised by Prof. Khayria Naguib:

A. Food Microbiology:

1- Microbiological and Chemical Studies on Domiati Cheese. M.Sc., Ain-Shams

University. Food Sci., Dept. (1965). (Mohamed Naguib).

2- Microbiological Studies on Pasteurized Market Milk. M.Sc., Ain-Shams

University. Food Sci., Dept. (1965). (Soheir El-Nockrashy).

3- Microbiological studies on Dye-Reduction and Keeping Quality Tests of Raw

Milk. M.Sc., Ain-Shams University. Food Sci., Dept. (1966). (Mohamed

Sabbour).

4- Factors Affecting the Microbiological Quality of Domiati Cheese. Ph.D., Ain-

Shams University. Food Sci., Dept. (1968). (Mohamed Naguib).

5- Microbiological and Chemical Studies on the Local Dried Milk of Sakka

Milk., M.Sc., Ain-Shams University Microbiology Dept. (1968), (Salem

Abdel-Ghani).

6- Studies on Some Pathogenic Bacteria in Milk and Some Dairy Products.

Ph.D., Ain-Shams University Microbiology Dept. (1973). (Mohamed

Sabbour).

7- Studies on the Microbiological and Keeping Quality of the Local Powdered

Milk. Ph.D., Ain-Shams University. Microbiology Dept. (1976). (Salem

Page 10: Mycotoxins Phycotoxins

Abd El-Ghani).

8- Effect of Some Preservatives on Some Milk Organisms. M.Sc., Ain-Shams

University. Microbiology Dept., (1977). (Nabil Fouad Tawfeek).

9- Microbiological and Chemical Quality of Local Market Rennet. M.Sc., El-

Azhar University. Food Sci., Dept. (1979). (Moustafa El- Shinawy).

10- Studies on Potentially Pathogenic Staphylococci Isolated From Dairy

Products. M.Sc., Ain-Shams University, Microbiology Dep., (1979). (Osama

Sharaf).

11- Selection of Starter Bacterial for Ras Cheese Production. M.Sc., Cairo

University, Microbiology Dept. (1980). (Elham Moustafa).

12- Preservation of Bacterial Starter Culturs for Dairy Industry. M.Sc., Cairo

University Food, Sci., Dept. (1980). (Kawther El-Shafei).

13- Microbiological Studies on Dried Milk and Effect of Storage. M.Sc., Cairo

University. Food Sci. Dept. (1980). (Ikram Mohamed)

14- Bacteriological Studies on Improvement of the Quality of Soft Cheese Made

from Dried Milk. M.Sc., Cairo University. Food Sci., Dept. (1980). (Zainab

Ibrahim).

15- Continuous Production of Bacterial Starter Culture for Dairy Industry. M.Sc.,

Cairo University. Food Sci., Dept. (1980). (Fatma Fathey)

16- Technical Comparison Between Soybean and Other Legumes. M.Sc., Zagazig

University. Food Sci. Dept. (1980). (Galal Mohamed)

17- Study on Conjugation of Gossibole with Proteins. M.Sc., El-Azhar University

(1981). (Ibrahim Foad).

18- Microbiological Studies on Certain Grains. M.Sc., Cairo University.

Microbiology Dept. (1981). (Badiaa Riad).

19- Studies on Strawberry. M.Sc., Suez Canal University (1982). (Sohair El-

Sayed)

20- Studies on the Use of Starters in the Manufacture of Cheese from Soybean

Milk. Ph.D., Ain-Shams University (1983). (Narges Hassan)

21- Effect of Preheating on Some Properties of Zabady Made from Buffelow’s

Milk. M.S., El-Azhar University (1983). (Effat Soliem)

22- Production of Fungal Protein Using Food Industry Wastes. M.Sc., Moshtohor

University (1983). (Hussein Azzaz).

23- Effect of Microbial Fermentation on Pesticide Residues in Milk. M.Sc., Ain-

Page 11: Mycotoxins Phycotoxins

Shams University (1983). (Assem Anwar)

24- Studies on the Processing of Some Legumes. Ph.D., Ain-Shams University

(1984). (Galal Mohamed)

25- Studies of the potential Hazard of Staphylococci in Egyptian Hard Cheese.

Ph.D., Ain-Shams University (1984). (Nabil Fouad Tawfeek)

26- Further Studies of Selection Starter of Ras Cheese. Ph.D., Cairo University

(1984). (Elham Moustafa).

27- Clean Milk Production. M.Sc., Ain-Shams University (1984). (Baher Abd El-

Khalil).

28- Studies on Producing Long Life Yoghurt. M.Sc., Cairo University (1984).

(Abou Baker Salim).

29- Studies on Soybean Protein and Used it in Some Dairy Products. M.Sc., Ain-

Shams University (1984). (Mousa Maaly Eid).

30- Studies on Some Microbiological Parameters on sousages. M.Sc., Ain-Shams

University (1984). (Ezzat Baumie).

31- Studies on Staphylococci and its Enterotoxin Isolated from Some Dairy

Products. Ph.D., Ain-Shams University (1985). (Osama Sharaf).

32- Utilization of By-Products of Sugar-Beet Industry in Production of Fungal

Protein and Enzymes. Ph.D., Zagazig University (1986). (Hussein Azzaz).

B. Mycotoxins :

33- Studies on Roquefort Cheese and Occurrence of Mycotoxins. M.Sc., El-Azhar

University (1979). (Ibrahim Hosny).

34- Effect of Processing on Aflatoxin M1 Content in Milk and Dairy Products.

M.Sc., Cairo University (1980). (El-Sayed Abd-Alla).

35- Studies on Aflatoxin in Milk and Dairy Products. M.Sc., El-Azhar University

(1981). (Ali Mahrous).

36- Effect of Aflatoxins on Some Hormonal Levels in Blood Plasma of

Mammals.M.Sc., Ain-Shams University (1982). (Kawther Mohamed).

37- Metabolism of Aflatoxin B1 in sheep. M.Sc., Ain-Shams University (1982).

(Mona Abd-El-Galil).

38- Effect of Aflatoxin on Some Physiological Aspects. M.Sc., Ain-Shams

University (1983). (Mosaad Attia Abdel-Wahhab).

39- Studies on Some Mycotoxins in Food. M.Sc., Cairo University (1983).

(Mohamed Nasr El-Dein).

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40- Studies on the Metabolism of Aflatoxin B1. In Ruminants. M.Sc., Ain-Shams

University (1983). (Shaaban Abd-El-Fatah).

41- Farther Studies on Disease Problems Resulting from Mycotoxins in Poultry

with Special Reference to control and Prevention. Ph.D., Cairo University

(1983). (Anwaar Mitwally).

42- Studies on Some Mycotoxins in Some Vegetables During Processing. M.Sc.,

Cairo University (1984). (Mahmoud Abo-Donia).

43- Effect of Processing on Mycotoxins in Legumes. M.Sc., Cairo University

(1984). (Hassan Ahmed Amra).

44- Studies on Mycotoxins in Fruits. M.Sc., Cairo University. Food Microbiology

(1984). (Ali Shalaby)

45- Studies on Vomitoxin. Ph.D., Cairo. University. Food Micobiology (1984).

(El-Sayed Abd-Alla)

46- Studies on PR Toxin. Ph.D., El-Azhar University. Food Micobiology (1984).

(Ibrahim Hosny).

47- Influence of Mycotoxin Production Affecting Factors on F-2, F-2 and

Ochratoxin Contamination of Grains. Ph.D. Azhar University, Food Sci.

Dept. (1983). (Ali Badawey).

48- Studies on Tremorgens. Ph.D., Cairo University (1987). (Hassan Amra).

49- Studies on Stregmatocystin in Some Grains. M.Sc., Cairo University. Food.

Sci., Dept (1987). (Emman Hegazi).

50- The Biological and Chemical Evaluation of Aflatoxin contaminated Rations

After Chemical Treatments. Ph.D., Ain-Shams University. Animal Prod.

Dept. (1988). (Mona Abd El-Gallil).

51- Some Physiological Aspects of Aflatoxin Treated Sheep. Ph.D., Ain-Shams

University. Animal Prod. Dept. (1988). (Kawther Mohamed).

52- Studies on Stregmatocystin in Dairy Products. M.Sc., Cairo University. Food

Sci., Dept (1988). (Yehia Hassan).

53- The Role of Afatoxins as a Potential Hazard in Different Diseases in Egypt..

M.Sc. Degree in Microbiology and Immunology -Faculty of Medicine - Ain

Shams Univ., Microbiology & Immunology Department (1998). (Sherine

Fawzi Hefez).

54- Effect of Aflatoxin B1 Treatment on Pregnancy, New born and Milk

Production in Mammals. Ph.D., Ain-Shams University. Animal Prod. Dept.

Page 13: Mycotoxins Phycotoxins

(Scientific Channel between Egypt & USA) (1989). (Mosaad Abdel-

Wahhab).

55- Decontamination of some mycotoxins in local and Imported dried fruits.

Ph.D. Cairo Univ. Food Sci. Dept. (2000). (Emman Megazy).

56- Studies on the Mycology and Mycotoxins of Peanut and Peanut products.

Suez Canal Univ. Faculty of Science, Microbiology. (Scientific Channel

between Egypt & USA) (2002). (Amal Mohamed Moustafa).

57- The Effect on Processing On Ochratoxin A Level in Green Coffee Beans. M.

Sc. Cairo Univ. Biochemistry Dept. (2002). (Nehad EzzEl-Din Amamed

Mohamed).

58- Studies on fumonisin B1 in corn and corn based products. Ph.D. Faculty of

Agriculture, Cairo University. Food Sci. Dept., (2003). (Heba, T. Mehasseb).

59- Studies on Sterigmatocystin in Some Foods Based on Wheat. M.Sc., Ain-

Shams University, Faculty of Agriculture, Food Science Dept.(2004). (Tarek

Ahmed El- Desoki).

60- EL-Desoky T.A.; Abdallah M.A.; Abdou H.M., Abdel-Galil M.M. and Naguib K.M.

(2006).Screening methods for the detection of sterigmatocystin in wheat. J. Union Arab

Biol. Cairo. 15; 107-122.

61- Study on use of Sorghum maize free from mycotoxins in food industry. Al-

Azhr University, Faculty of Agriculture, Food Science Dept. (2008). (Sherief

Ramzy Mohamed).

C. Marine and Fresh water Toxins and Other Chemical Contaminants:

62- Correlation Between Freshness Indices and Degree of Fish Decomposition.

Ph.D., Ain Shams University. Food Sci. Dept. (1986). (Ali R. Shalaby).

63- Specified Deviced Techniques for Detecting Fish Contaminates. Ph.D., Ain

Shams University. Food Sci. Dept. (1986). (Mahmoud Abou Donia).

64- Studies on the Production and Quality Control of Fish Meal. M.Sc. Suez

Canal University Food Sci. Dept (1988). (Ahmed M. Ayesh).

65- Identification and Detection of Some Pesticide Residues and Heavy Metals in

Fish, Water, Sediment Collected From River Nile (El-Malek El-Saleh) and

Qaroun Lake. M.Sc., Cairo University Food Sci. Dept (1990). (Heba, T.

Mehasseb)

66- Fish meal Production, Biological Evaluations and Elimination of its Toxic

Amines. Ph.D., Cairo University. Food Sci. Dept (1992). (Ahmed M. Ayesh).

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67- Studies on Algal Toxins in Fish, Shell Fish and Water. M.Sc., Cairo

University. Food Sci. Dept (1992). (Emad M. Ali).

68- Distribution Pattern of Freshwater Algae and their toxins in Raw and

Municipal water in Port-Said Province. Ph.D., Suez Canal Univ. Botany Dept.

(2002). (Abeer Shaker Amin).

PUBLICATIONS:

A. Food Microbiology:

1. Khayria Naguib and Ahmed, Z. F. (1962). Guar flour utilization as a stabilizer in

ice- cream making and its effect on some physical and microbiological

properties of the products. Egypt Pharm. Bull. 44 (4).

2. Khayria Naguib and Janoschek, A. (1965). The resistance of propionic acid

bacteria to Sodium chloride. Deutche Molkerei – Zeitung, 86-20.

3. Khayria Naguib (1966). Microbiological quality of pasteurized milk in Cairo. First

Egyptian Microbiological Congress Cairo, Egypt.

4. Khayria Naguib (1966). Improvement of microbiological properties of pasteurized

milk and a simultaneous study of the line of the production in central factory.

First Egyptian Microbiological Congress, Cairo.

Results of No. 3 & No. 4, were Successfully Applied in Misr Food and Dairy

Company and the Microbiological Problem Facing them in Production of

Pasteurized Milk was Completely Dissolve.

5. Kahyria Naguib and Abd El-Ghani, S. (1972). Spray dried milk of the Sakha

plant. I. Quality control studies. J. Milk and Food Tech. 35, 1, 35-38.

6. Khayria Naguib and Abd El-Ghani, S. (1972). Spray dried milk of the Sakha plant

II. Identification of predominating microorganisms. J. Milk and Food Tech. 35,

1, 45- 48.

7. Khayria Naguib and Negm, A. (1972). Microbiological and chemical studies on

zabady. Milchwissenchaft 27 (9), 572- 573.

8. Khayria Naguib and Negm, A. (1972). Acetaldehyde and diacetyl production in

zabady and zabady cultures. Milchwissenschaft 27 (12), 756-758.

9. Khayria Naguib and Hussein, L. (1972). The Effect of hydrogen peroxide

treatments on the bacteriological quality and nutritive value of milk.

Milchwissenschaft 27 (12), 758-762.

10. Khayria Naguib (1972). Sorbic acid and potassium sorbate as fungicide for

Gouda cheese during ripening and storage. Milchwissenschaft 27 (11), 702-

Page 15: Mycotoxins Phycotoxins

704.

11. Khayria Naguib (1972). Hydrogen peroxide treatment of milk for Domiati

cheese. the Aust. J. of Dairy Techn. 27 (2), 56-60.

12. Khayria Naguib and Sabbour, M. M. (1972). The Viability of Salmonella

typhimurium in Ice-Cream. Zbt. Bakt. Abt. 11, Bd. 128, 5, 93-96, 1972.

13. Khayria Naguib and Sabbour, M. M. (1972). The Viability of Salmonella

typhimurium in Zabady. J. Microbiol. 112, 97-101.

14. Khayria Naguib and Shouman, T. (1972). Identification and typing of clostridia

in raw milk in Egypt. J. Appl. Bacteriol. 35, 525-530.

15. Khayria Naguib and Shouman, T. (1973). Occurrence of Clostridia in White

Pickled Cheese. Zbt. Bakt. Abt. 11, Bd. 128, S. 84-87.

16. Khayria Naguib (1973). Evaluation of Bacto-Strip Techniques for the Detection

of Coliforms in Pasteurized Milk. Zbt. Bakt. Abt. 11, Bd. 128, S. 88-92.

17. Naguib, M. M.; Khayria Naguib and El-Sadek, G. M. (1973). The Survival of

Coagulase-Positive Staphylococci and Coliforms in Domiati Cheese.

Mikrobiologi. Ja, 10 (2), 243-248.

18. Khayria Naguib and Naguib, M. M. (1974). Factors affecting the quality of

Domiati cheese. I. Effect of heat treatment. Egypt. J. Diary Sci. 2, 55-73.

19. Khayria Naguib and Naguib, M. M. (1974). Factors affecting the quality of

Domiati cheese. II. The selection of single strain starters and determination of

their rates of addition for cheese manufacture. Egypt. J. Dairy Sci. 2, 161-167.

20. Naguib, M.M.; El-Shibiny and Khayria Naguib (1975). Microbioogical and

chemical quality of Egyptian market rennet. Egypt. J. Dairy Sci. 3, 153-160.

21. Naguib, M.M.; El-Nockrashy, S.; Sabbour, M.M. and Khayria Naguib. (1978).

Occurrence of coagulase-positive Staphylococci in Egyptian raw milk and dairy

products. 1. Ras, Karish and Domiati cheeses. Res. Bull. 878, Ain-Shams Univ.,

Fac. of Agric.

22. EL-Nockrashy, Soheir, Sabbour, M.M. and Khayria Naguib (1978). Occurrence

of coagulase-positive Staphylococci in Egyptian raw milk and dairy products. 2.

Ice Cream and Zabady. Res. Bull. 945, Ain- Shams Univ., Fac. of Agric.

23. Sabbour, M. M., Naguib, M. M., El-Nockrashy, S. and Khayria Naguib (1979).

Occurrence of coagulase-positive Staphylococci in Egyptian raw milk and dairy

products. 3. Counts and types of Staphylococci prevailed in raw milk. Egypt. J.

Food Sci. 7 (1), 1-5.

Page 16: Mycotoxins Phycotoxins

24. Khayria Naguib, Naguib M. M., Sabbour, M. M. and El-Nockrashy, S. (1979).

Occurrence of coagulase-positive staphylococci in Egyptian raw milk and dairy

products. 4. Identification of cultures isolated from Sllo and Mannitol Salt Agar

Media.Research Bulletin, No. 983, Ain-Shams Univ., Fac. of Agric.

25. Khayria Naguib; Sabbour, M. M., Mahmoud, S. A. Z., Hazem, A. and Sharaf, O.

M. (1979). A survey of the incidence of coagulase-positive staphylococci in

pasteurized milk and imported dried milk in Egypt. Identification of the isolated

cultures. Res. Bull. 1183, Ain-Shams Univ., Fac. of Agric.

26. Mahmoud, S. A. Z., Khayria Naguib, Sabbour, M. M., Hazem, A. and Sharaf,

O.M. (1979). Occurrence of coagulase- positive staphylococci in Egyptian sour

and butter milk. Identification and classification of the isolates. Res. Bull. 1184,

Ain-Shams Univ., Fac. of Agric.

27. Mahmoud, S. A. Z., Khayria Naguib, Sabbour, M. M. Hazem, A. and Sharaf, O.

M. (1979). Incidences of Staphylococci in Egyptian raw milk. Res. Bull. 1185,

Ain-Shams Univ., Faculty of Agric.

28. Mahmoud, S. A. Z., Sabbour, M. M., Naguib, M. M., Khayria Naguib, Hazem,

A. and Sharaf, O. M. (1980). Production of coagulase, hemolysins and

thermonuclease by staphylococci and Micrococci from milk and dairy products.

Arch. Fur Lebensmittelhygiene 31 (1), 5-6.

29. Mahmoud S.Z., Khayria Naguib, El-Nockrashy, S. and Tawfeek, N. (1984). Use

of hydrogen peroxide as dairy preservative. Egypt. J. Dairy Sci. 12 (2), 163-172.

30. Khayria Naguib, Mahmoud, S. A. Z., El-Nockrashy, S. and Tawfeek, N. (1985).

Use of Nisin as Dairy Preservative. Egypt. J.Dairy Sci. 13 (2), 167-176.

31. Mahmoud S.Z., Khayria Naguib, El-Nockrashy, S. and Tawfeek, N. (1985). Use

of potassium nitrite as a dairy prservative. Egypt. J. Dairy Sci. 13 (2), 167-176.

32. Khayria Naguib, S.Z. Mahmoud, S. Z., El-Nockrashy, S. and Tawfeek., N

(1985). Effect of Formaline on Some Desirable and Non-Desirable

Microorganisms. Egypt. J. Dairy Sci. 13, 159-166.

33. Mahmoud, S. Z., Naguib, M. M., El-Nockrashy, S., Rifaat, A. A., Tawfeek, N.

and Khayria Naguib (1985). Survey of Staphylococcus aureus in market

Egyptian Ras cheese and the presence of Enterotoxins type A and B. Egypt. J.

Food Sci. 13, 15-19.

34. Khayria Naguib, M. El-Sawy, Rawia F. Gamal and O.M. Sharaf. (1986).

Incidence of Staphylococcus aureus and their enterotoxins (A or B) in some

Page 17: Mycotoxins Phycotoxins

Egyptian soft dairy products. Annals Agric. Sci., Fac. Agric., Ain-Shams Univ.

31 (1), 41-46.

35. El-Sawy, M.; Gamal R. F., Khayria Naguib ; Sharaf, O. M. (1986).Viability of

Staphylococcus aureus and presence of TN-ase and enterotoxins in Egyptian

Zabady during manufacturing and storage at different temperatures. Annals

Agric. Sci., Fac. Agric., Ain-Shams Univ. 31 (1), 53- 67

36. Gamal, R. F., El-Sawy, M., Naguib, Kh. and Sharaf, O. M. (1986).Survival of

enertoxigenic Staphylococcus aureus type A in Egyptian butter Egypt. J.

Microbiol. Special Issue, 37-46.

37. Naguib,M. M., Mahmoud, S. Z., Sabbour; M. M., Rifat, A. A, Tawfeek, N. and

Khayria Naguib (1987).Growth and Enterotoxin Production of Enterotoxigenic

Staphylococcus aureus in Ras Cheese During Ripening. Egypt. J. Food Sci. 15

(2), 133-139.

2. Mycotoxins:

38. Naguib, N.M.; Khayria Naguib, Pohland, A.E. and Cambell. (1978). Aflatoxin

residues in Egyptian foods. 1. Rice, corn and peanut. 12th Int. congr.

Microbiology, Munchen, No. H.4, P 167.

39. Mahrous, A.B., Nguib, M.M., Khayria Naguib, Pohland, A.E. and Cambell.

(1978). Aflatoxin residues in Egyptian foods. 2. Milk and dairy products. 12th

Int. Congress. Microbiology, Munchen, No. H.5, P 168.

40. Naguib, M.M., Khayria Naguib and El-Khadem, M. (1979).Aflatoxin residues in

Egyptian foods. 3. Lentils and broad beans. Second Arab Conference for Food

Science and Technology, Riyad, P. 83.

41. Naguib, M. M., El-Arian, A. F., El-Tawab, G., Khayria Naguib and Mahrous, A.

B. (1979)..Aflatoxin residues in Egyptian foods. 4. The comparative annual

occurrence in raw and pasteurized milk. Egypt. Society of Appl. Microbiol..

Annual Meeting, 27, 311-16.

42. Khayria Naguib, Naguib, M.M., Pohland, A.E. and Campbell, A.D. (1979).

Aflatoxin in Egyptian foods. 5. Dried fruits; figs, dates and raisin. 4th

International IUPAC Symposium on Mycotoxins and Phycotoxins, Lausane,

No. 316.

43. Naguib, M.M., Khayria Naguib, Pholand, A.E. and Campbell, A.D. (1979).

Aflatoxins in Egyptian foods. 6. Beans, Peas and Cowpeas. 4th International

IUPAC Symposium on Mycotoxins and Phycotoxins, Lausane, No. 317.

Page 18: Mycotoxins Phycotoxins

44. El-Khadem, M., Naguib M.M., Khayria Naguib, Ahmed, N.M. and Pholand,

A.E. (1979). Effect of storage temperature and relative humidity on Egyptian

peanut Mycoflora. 4th International IUPAC Symposium on Mycotoxins and

Phycotoxins, Lausane, No. 210.

45. Naguib, M.M., Khayria Naguib, El-Khadem, M. and Pholand, A.E. (1979).

Effect of storage temperature and relative humidity on aflatoxin development in

Egyptian peanut. 4th International IUPAC Symposium on Mycotoxins and

Phycotoxins, Lausane, No. 210.

46. El-Khadem, M., Khayria Naguib and Naguib, M.M. (1983). Aflatoxins in

foodstuff in Egypt. II. Broad beans mycoflora and toxicity. Proceeding of the

International Symposium on Mycotoxins.

47. Naguib, M.M. and Khayria Naguib. (1983). Metabolism of aflatoxin B1 in

buffaloes. Proceeding of the International Symposium on Mycotoxins, Cairo,

Egypt.

48. Khayria Naguib, Naguib, M.M., Nour, M.A., El-Khadem and Hosny, I.M.

(1983). Studies on mycotoxins in local Roquefort cheese. Proceeding of the

International Symposium on Mycotoxins, Cairo, Egypt.

49. Matter, M. M., Khayria Naguib and Naguib, M. M. (1983). Biological effect of

aspergillus flavus on Iribolium castanum. Proceeding of the International

Symposium on Mycotoxins, Cairo, Egypt.

50. Abd El-Salam, M. M., El-Shibiny, S., Naguib, M.M., Khayria Naguib and

Mohamed, A.A. (1983).Effect of injested and intraruminal ingested aflatoxin B1

on the chemical composition of buffalo milk. Proceeding of the International

Symposium on Mycotoxins, Cairo, Egypt.

51. Khayria Naguib, Naguib, M.M., Sahab, A.F. and Diab M.M. (1983). Studies on

fungi associated with onion bulbs. I-Screening During Harvest, Transportion

and Storage. International Symposium on Mycotoxins, Cairo, Egypt.

52. Khayria Naguib, Naguib, M.M., Sahab, A.F., Diab, M.M. and Abd-Alla A. El-

Sayed. (1983). Studies on fungi associated with onion bulbs. II-Pre-Sumptive

Screening for Mycotoxins. International Symposium on Mycotoxins, Cairo,

Egypt.

53. Khayria Naguib, Naguib, M. M., El-Kersh, T. and Abdallah, E. (1983). Studies

on fungi associated with onion bulbs. III-Toxicity and Mutagenicity of the

Isolates Using the Bioassay Methods. International Symposium on Mycotoxins,

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Cairo, Egypt.

54. Naguib, M. M., Khayria Naguib, Alyan, A., El-Shemy, N. and Amra, H. (1983).

Fate of aflatoxin B1 residues during processing and storage of beans (Phaseolus

vulgaris) and cow-peas (Vigna sinensis). International Mycotoxin Symposium

on Mycotoxins, Cairo, Egypt.

55. Khayria Naguib, Naguib, M. M., El-Khadem, E., Alyan, A. and Ibrahim, M. N.

(1983). Effect of processing on the stability of aflatoxin B1 on broad beans.

International Symposium on Mycotoxins, Cairo, Egypt.

56. Khayria Naguib, El-Lethy, A., Naguib, M. M., El-Khadem, M. and Riad, B.

(1983). Mycological studies on corn and wheat. International Symposium on

Mycotoxins, Cairo, Egypt.

57. Metwally, M. M., Naguib, M.M., Khayria Naguib, Abdel Nabi, A. and

Abdallah, E. (1983). A Comparison Between Aflatoxin M1 Extraction Methods

for Milk and Dairy Products. International Symposium on Mycotoxins, Cairo,

Egypt.

58. Metwally, M. M., Khayria Naguib, Naguib, M. M., Abdel Nabi, A. and Abd-

Alla, E. (1983). Effect of Milk Heat Treatment (Drying, Pasteurization and

Boiling) on Aflatoxin M1 Content. International Symposium on Mycotoxins,

Cairo, Egypt.

59. Metwally, M. M., Khayria Naguib, Naguib, M. M., Abdel Nabi, A. and

Abdallah, E. (1983). The effect of making ras cheese and krish cheese on the

aflatoxin M1 content of milk. International Symposium on Mycotoxins, Cairo,

Egypt.

60. Khayria Naguib, Naguib, M. M., Alian, A., El-Shimy, N. and Shalaby, A. R.

(1983). Fate of aflatoxin B1 in orange juice during process and storage. J. Egypt.

Soc. Toxicol. 2,110-121.

61. Naguib, M. M., Khayria Naguib, Alian, A., Sahab, A. F., El-Shimy, N. and

Shalaby, A. R. (1985). Fungal flora associated with orange citrus spoilage fruits

with Special References to Aflatoxin Production. J. Egypt. Soc. Toxicol. 2, 98-

109.

62. Naguib, M. M., Khayria Naguib, Sahab, A. F., El-Shwah, E.T., Sallam, Y.I. and

Abou Donia, M. A. (1985). Fungal flora associated with tomato fruits spilage

and their Potential Production of Mycotoxins. J. Egypt. Soc. Toxicol. 12, 11-15.

63. Khayria Naguib, Naguib, M. M. Diab, A. M., Sahab, A. F. and Amra, H. (1988).

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Occurrence of aflatoxins in several groundnut cultivars infected with strains of

Aspergillus flavus. Proceeding International Workshop on aflatoxin

contamination of groundnut. ICRISAT Centre, Hyderabad, India.

64. Khayria Naguib, Metwally, M. and Abdallah, E. (1988). Toxicity of

Deoxynivalenol Using Bioassay Techniques. 7th International IUPAC

Symposium on Mycotoxins and Phycotoxins. Tokyo, Japan.

65. Khayria Naguib, Metwally, M. and Abdallah, E. (1988) A Survey on the

occurrence of deoxynivalenol in wheat and corn. 7th International IUPAC

Symposium on Mycotoxins and Phycotoxins. Tokyo, Japan.

66. Metwally, M., Khayria Naguib and Abdallah., E. (1988). Fate of deoxynivalenol

(DON) during processing of bread and macaroni from contaminated flour. 7th

International IUPAC Symposium on Mycotoxins and Phycotoxins. Tokyo,

Japan.

67. Sahab, A.E.; M. Metwally, Khayria Naguib and El-Sayed Abd-Alla. (1988).

Fungal flora associated with wheat cultivars with special references to

vomitoxin production. 7th International IUPAC Symposium on Mycotoxins

and Phycotoxins. Tokyo, Japan.

68. Khayria Naguib, A.E. Sahab, M. Metwally and El-Sayed Abd-Alla. (1988).

Fungal Flora Associated with Corn Cultivars with Special References to

Vomitoxin Production. 7th International IUPAC Symposium on Mycotoxins

and Phycotoxins. Tokyo, Japan.

69. Metwally, M., Khayria Naguib and Abdallah, E. (1988). Deoxynivalenol in

Milk: Thin layer chromatography method and nontransmission to milk. 7th

International IUPAC Symposium on Mycotoxins and Phycotoxins. Tokyo,

Japan.

70. Sahab, A.E.; M. Metwally, Kh. Naguib and El-Sayed Abd-Alla (1989). Isolation

and identification of associated fungi with wheat grains with special references

to vomitoxin roduction. Fungal flora associated with wheat cultivars with

special references to vomitoxin production. Afr. J. Agric. Sci.16 (1+2), 53-66.

71. Abd El-Wahhab, M. A. and Khayria Naguib. (1990). Aflatoxicosis in Rabbits 1.

Histopathological study in liver of rabbits treated with aflatoxin B1. The

International Symposium on Mycotoxins and Phycotoxins 56. p82. Cairo,

Egypt.

72. Amin, S.O.; W.E. Abdelaal, M.A. El-Fouly, M.A. Abdel-Wahhab and Khayria

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Naguib. (1991). Aflatoxicosis in rabbits II. Histopathological and histochemical

study of mammary gland during pregnancy and lactation as affected by

aflatoxin B1 administration. Egypt. J. Anim. Prod. 28 (2), 179-189.

73. Abdallah, E., Badawey, A., Faheid, S. M. M. and Khayria Naguib (1992). Effect

of chemical leavening agent on aflatoxin B1 content during cookies preparation.

Bull. Nutr. Inst. 12, (1), 111-121.

74. Abd-Alla, E., Badawey, A., Narges, H. M. and Khayria Naguib

(1992).Correlation of zinc and phytic acid content with aflatoxins production on

soybean. Bull. Nut. Inst. 12, 111-121.

75. Shalaby, A. R., Badawey, A. and Khayria Naguib. (1993). Rapid micro-method

for the extraction and determination of aflatoxin in animal and human liver

tissues. Bull. Nut. Inst. 13, 45-55. غير موجود اصلا ع النت

76. Gommaa, M. N., Ayesh, A. M., Soliman, K. M. and Khayria Naguib. (1994).

Assessment of toxicity of aflatoxins products detoxified by high pressure

ammoniation. The Afr. J. Mycol. Biotechnol. 2 (3), 228- 236.

77. Mayura K., Abdel-Wahhab, M. A., Sarr, A. B., McKenzie, K. S., Edwards, J. F.

Khayria Naguib, Amin, S. O., Phillips, T. D. (1995). Selective chemisorbents

of aflatoxin B1 by HSCAS: Prevention of developmental toxicity in the rats.

34th Annual Meeting, Baltimore, MD USA; The Toxicologist 15 (1).

78. Gommaa, M. N. E., Ayesh, A.M., Abdel-Galil, M. M. and Khayria Naguib.

(1997). Effect of High pressure ammoniation procedure on the detoxification of

aflatoxins. J. Mycot. Res.13, 23-34.

79. Amra, H. A., Miller, M., Sahab, A. F. and Khayria Naguib. (1997). Fusarin and

Fumonisin Production by Fusarium moniliforme isolated form stored Egyptian

Corn. J. Vet. Pharmacol. Therap. 20 (1), 272-273.

80. Soliman, K. M., Ayesh, A. M., Manal, A. M. and Khyria Naguib (1998). Fix-A-

Tox in Agriculture: I. Effect of Aflatoxin decontamination by a selective

chemosorbent material on the Oreochromis Niloticus with considered fish

processing efficiency. J. Egypt. Ger. Soc. Zool. 25, 1-19.

81. Mayura, K., Abdel-Wahhab, M. A. McKenzie, K. S., Sarr, A. B., Edwards, J. F., Naguib,

K. and Phillips, T. D. (1998). Prevention of Maternal and Developmental Toxicity in

Rats via Dietary inclusion of Common Aflatoxin Sorbents: Potential for Hidden Risks.

Toxicol. Sci. 41, 175-182.

82. Ayesh, A. M., Gommaa, M. N .E. and Khayria Naguib. (2000). Aflatoxins percent

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recovery of CB and immunoaffinity column procedure in black and green tea. J. Egypt.

Soc. Toxicol. 22, 35-40.

83. Khayria Naguib (2000). Mycotoxins: problems and future strategies. Egyptox-Workshop

on Environmental Chemistry and Toxicology. In Collaboration Ministry of State for

Scientific Research. National research Center, Dokki, Cairo, Egypt with UNESCO.

pp.15- 24.

84. Abdel-Wahhab, M. A., Amer, H. A., Hassan, N. S., Hassan, A. M. and Khayria

Naguib.(2002). Effects of garlic and cabbage extracts on fumonisin-induced toxicity in

rats. J. Egypt. Soc. Toxicol. 26, 1- 12.

85. Abdel-Wahhab, M. A., Hassan, A. M., Amer, H.A and Khayria Naguib. (2002).

Antioxidant effects of garlic and cabbage on fumonisin-induced developmental toxicity

and sphingolipids metabolism in rats. J. Egyt. Soc. Toxicol. 26, 23-29.

86. Khayria Naguib and Abdel-Wahhab, M. A. (2002). Antioxidant properties of certain

natural products against mycotoxocosis. (Special edition) Herbal Medicine P. 24-26.

87. Abdel-Wahhab M. A., Hassan A. M., Amer H. A. and Khayria Naguib. (2004).

Prevention of Fumonisin-induced maternal developmental toxicity in rats by certain

plant extracts. J. Appl. Toxicol. 19(6), 469- 474.

88. Nehad, E. A., Farag, M. M., Kawther, M. S., Abdel-Samed, A. K. and Khayria Naguib

(2005). Stability of OTA during processing and decaffination in commercial roasted

beans. J. Food Add. Cont. 22 (8), 761 -767.

89. Tarek A. El-Desoky, Abdallah, M. A., Abdou, H. M., Abdel-Galil, M., and Naguib, Kh.

M. (2006). Screening methods for the detection of Sterigmatocystin in Wheat. J. Union

Arab Biol. Cairo, Vol (15B): 107-122.

89. Nehad, E. A., Farag, M. M., Kawther, M. S., Abdel-Samed, A. K. and Khayria Naguib

(2007).An exposure and intake assessment of ochratoxin A from imported coffee beans

in Egypt. World journal of Agricultural Sciences 3 (3) : 285-294.

90. Ahmed A. El-Kady, Hafiza A. Sharaf, Mahmoud A. Abou-Donia, Samir Abbès, Jalila

Ben Salah-Abbès, Khayria Naguib, Ridha Oueslati and Mosaad A. Abdel-Wahhab

(2009).

Adsorption of Cd2+ ions on an Egyptian montmorillonite and toxicological effects in rats.

Applied Clay Science, Volume 44, Issues 1-2, April 2009, Pages 59-66

III. Marine Toxins and Other Chemical Contaminants:

90. Khayria Naguib, Ayesh A., Abdel-Baki, M. M. and El-Zayet, F. (1988).

Biogenic Amines and Bacterial Counts during Fish Meal Processing. The 102nd

AOAC Annual International Meeting, Florida, USA.

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91. El-Zayet, F., Abdel-Baki, M. M., Khayria Naguib and Ayesh, A. (1988). Simple

Method for the Determination of Biogenic Amines in Fish Meal. The 102nd

AOAC Annual International Meeting, Florida. USA.

92. Abdel-Baki, M. M., El-Zayet, F., Khayria Naguib and Ayesh A. (1989). Quality

Assessment of Fish Meal Used in Egypt. The 14th International Congress of

Nutrition, Seoul-Korea.

93. Abdalla M. A., Hassan I. M., Shalaby A. R. and Khayria Naguib. (1990).

Physicochemical and Bacteriological Changes Occuring During Storage of

Sardine Fish. The 14th International Congress of Nutrition, Seoul-Korea.

94. Abdalla M. A., Hassan I. M., Shalaby A. R. and Khayria Naguib.

(1990).Correlation between biogenic amines, chemical changes and stability of

sea bream fish during storage at –80 o

C. The 14th International Congress of

Nutrition, Seoul-Korea.

95. Hassan I. M., Abdallah M. A., Shalaby A. R. and Khayria Naguib (1990).

Relation between salting and chemical changes of mullet and sardine fish with

emphasis on biogenic amines. International Symposium and Workshop on Food

Contaminants: Mycotoxins and Phycotoxins, Cairo, Egypt.

96. Hassan I. M., Abdallah M. A., Shalaby A. R., and Khayria Naguib. (1990).

Physicochemical and Bacteriological Changes Associated with Degradation of

Mullet and Sea Bream Fish. International Symposium and Workshop on Food

Contaminants: Mycotoxins and Phycotoxins, Cairo, Egypt.

97. Hassan I. M., Abadllah M. A., Shalaby A. R. and Khayria Naguib. (1990).

Biogenic amines as indicator of fish freshness. International Symposium and

Workshop on Food Contaminants: Mycotoxins and Phycotoxins, Cairo, Egypt.

98. Hassan I. M., Abdallah M. A., Shalaby A. R. and Khayria Naguib. (1990). Fate

of biogenic amines and other chemical indices during canning process of

sardine fish. International Symposium and Workshop on Food Contaminants,

Mycotoxins and Phycotoxins, Cairo, Egypt.

99. Khayria Naguib, Naguib M. M., Amra, H. A. and Abdallah, E. M. (1990).

Survey of ciguatoxin like- compounds in different Egyptian fish. International

Symposium and Workshop on Food Contaminants: Mycotoxin and

Phycotoxins, Cairo, Egypt.

100. Khayria Naguib, Naguib M. M. and Amra H. A. (1990). Application of stick

enzyme immunoassay (S-EIA) in Ciguatoxin like-compounds in Egyptian fish.

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International Symposium and Workshop on Food Contaminants: Mycotoxin and

Phycotoxins, Cairo, Egypt.

101. Morsi. K. M., Afify, S., Khayria Naguib, Badei A. Z. M. and Ayesh A. M.

(1992). Effect of dietary fish meal and biogenic amines on chicks. Egypt. J.

Comp. Pathol. Clin. Pathol. 5(2), 12-16.

102. Khayria Naguib, Ayesh, A. M. and Shalaby A. R. (1995). Studies on the

determination of biogenic amines in foods 1.Development of a TLC method for

the determination of eight biogenic amines in fish. J. Agric. Food. Chem., 43,

134-139.

103. Gomaa, M. N. E., Abou Arab, A. A. K., Badawy, A. and Khayria Naguib.

(1995). Distribution pattern of some heavy metals in Egyptian fish organs. J.

Food Chem. 35, 385-389.

104. Abou Arab, A. A. K., Gomaa, M. N. E., Badawy, A. and Khayria Naguib.

(1995). Distribution of organochlorine pesticides in the Egyptian aquatic

ecosystem. J. Food Chem. 54, 141-146.

105. Amra H. A., Ayesh A. M., Abou-Arab A. A. K. and Khayria Naguib. (1995).

Survey of Ciguatoxin-like Substances in imported scomberomorous and

sardinalla species from Egyptian markets. J. Egypt. Ger. Soc. Zool. 17 (A), 69-

77.

106. Ayesh A. M., Amra H. A., Abu-Arab A. A. K. and Khayria Naguib (1995).

Detection and determination of eight biogenic amines in frozen mackerel

(Scomberomorous Sp.) and sardine (Sardinella Sp.) using HPLC. J. Egypt. Ger.

Soc. Zool. 17 (A), 121-135.

107. Gamaa, M. N. E., Khayria Naguib, Hassan, M., Aly, E. M. (1995). Shellfish

poisoning in Egyptian marine environment. J. Union Arab Biol. 3 (A), 197-211.

108. Abou-Arab A. A. K., Ayesh A. M., Amra H. A. and Khayria Naguib. (1996)

Characteristic levels of some pesticides and heavy metals in imported fish, J.

Food Chem. 57 (4), 487-492.

109. Soliman, K. M., Abou-Arab, A. A. K., Badawy, A. and Khayria Naguib.

(1998). Heavy metal contamination levels in Egyptian vegetables and fruits and

removal by washing procedure. Bull. Nut. Inst. 17 (2), 120-144.

110. Abou-Arab, A. A. K., Soliman, K.M., Amra, H.A. and Khayria Naguib. (1998).

Pesticide residue contents in Egyptian vegetables and fruits and removal by

washing. Bull. Nut. Inst. 18 (2), 117-138.

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111. Abou-Arab, A. A. K., Soliman, K. M., El-Tantawy, M. E., Badeae, R. Ismail

and Khayria Naguib. (1999). Quantity estimation of some contaminants in

commonly used medicinal plants in the Egyptian market

112. Gomaa, M. N., Rawi, S. and Khayria Naguib (1999). Toxicological studies of

cyanobacterial toxin of Oscillatoria limnetica isolated from the solar lake in

Sinai. J. Egypt. Soc. Toxicol. 21, 15-21.

113. Aly, M. S., Naguib, M. M., Khayria Naguib (2000). Relationship between

algosphere and free water bacteria in Solar Lake (Sinai). Egypt. J. Phycol. 1,

195-201.

114. Gomaa, M. N., Abo–Elenein, N. M., Khayria Naguib, Sayed, R. (2000).

Neurotoxicity of sea anemone Gyrostoma Hellanthus from the Red Sea. J.

Egypt. Soc. Toxicol. 22, 75-81.

115. El-Kady. A.A., Sharaf, A.A., Aboudonia M. A., Naguib, Kh., and Abdel-

Wahhab, M.A. (2008). Egyptian montmorillonite adsorbs Cd+2

and almonirates

its toxicity in rats. Accepted in Applied Clay Science.

116. El-Kady. A.A., Sharaf, A.A., Aboudonia M. A., Naguib, Kh and Abdel-

Wahhab, M.A. (2009). Egyptian montmorillonite adsorbs Cd+2 and almonirates

its toxicity in rats. Applied Clay Science. 44(1-2), 59-66.

117. M.A. Abdel-Wahhab, M.I.M. Ibrahim, T.A. Abo-Elhawa, K.M. Naguib.

(2011). Modification and validation for the procedure of immunoaffinity

column and HPLC method for the determination of aflatoxin B1 in tobacco.

S292 Abstracts / Toxicology Letters 205S (2011) S180–S300.

118. K.M. Naguib, N.S. Hassan, A. A. El-Nekeety, M.I.Ibrahim, S.R. Mohamed,

M.A. Abdel-Wahhab.(2011). Safety use of ozone gas in the degradation of

aflatoxin in tobacco and prevention its toxicity in rats. Abstracts / Toxicology

Letters 205S (2011) S60-S179.

119. Mosaad A. Abdel-Wahhab1, Khaled Gamil, Ahmed A. El-Kady, Aziza A. El-

Nekeety, and Khayria M. Naguib.(2011). Therapeutic Effects of Korean Red

Ginseng Extract in Egyptian Patients with Chronic Liver Diseases. J. Ginseng

Res. 35,(1), 69-79.

120. El-Desouky, T.A.; Sharoba, AMA.; A I El-Desouky, El-Mansy HA and Khayria

Naguib. (2012). Effect of Ozone Gas on Degradation of Aflatoxin B1 and

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Aspergillus Flavus Fungal. Environment Analytic Toxicol. Volume 2, Issue 2,

1-6.

121. El-Desouky, T.A.; Sharoba, AMA.; A I El-Desouky, El-Mansy HA and Khayria

Naguib. (2012). Evaluation of ozone gas as an anti-aflatoxin B1 in wheat grains

during storage. Journal of Agroalimentary Processes and Technologies 2012, 18

(1), 13-19.

122. El-Desouky, T.A ; May, M. Amer and Khayria Naguib. (2012).Effects of pan bread

making on zearalenone levels in artificial contaminated wheat flour. In press in

Journal Hungarian journal of industry and veszprém. 40(2):107-111.

123. El-Desouky, T.A. and Khayria Naguib. (2013). occurrence of zearalenone

contamination in some cereals in Egypt. Journal of Agroalimentary Processes and

Technologies, 19 (4), 445-450.

124. El-Desouky, T.A.; Sharoba, AMA.; A I El-Desouky, El-Mansy HA and Khayria

Naguib. (2013). Effect of ozonation of wheat grain on quality bread factory. Journal

of Agroalimentary Processes and Technologies, 19 (1), 1-9.

125. El-Desouky T.A, May, M. Amer and Khayria Naguib. (2013). Effect of fenugreek

seeds extracts on growth of aflatoxigenic fungus and aflatoxin B1 production. Journal

of Applied Sciences Research, 9(7): 4418-4425.

126. Sherif S. Mohamed, El-Desouky.T.A, Sherif R. Mohamed., Khayria M.

Naguib, Mustafa Helmy. (2015). Antioxidants compounds from rice straw extracts

and their effect on Diazinon insecticide hazard. Middle East Journal of Applied

Sciences, 5(3), 687-694.

127. El-Desouky.T.A, Sherif R. Mohamed., Sherif S. Mohamed and Khayria M.

Naguib (2015). Protective effect of aqueous extract pomegranate peel against

sterigmatocystin toxicity in rat. Journal of Drug Delivery & Therapeutics. 5(5):9-18.

128. Sherif R.M, El-Desouky, TA.,Ahmed M.S.H, Sherif S.M ,Naguib K.H.

(2016). Modified Rice Straw as Adsorbent Material to Remove Aflatoxin B1 from

Aqueous Media and as A fiber Source in Fino Bread. journal of toxicology. Volume

2016, Article ID 6869582.

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129. Osman MA, Salama A, Naguib KHM, Sherif SR (2017) Fungi and

Mycotoxins Associated with Egyptian Sorghum Grains. MOJ Toxicol 3(3): 00052.

DOI: 10.15406/mojt.2017.03.00052.

130. Goda, A.A., Naguib, K.M., Mohamed, M.M., ...Gissendanner, C.R., El Sayed,

K.A. (2016). Astaxanthin and docosahexaenoic acid reverse the toxicity of the maxi-

K (BK) channel antagonist mycotoxin penitrem A. Marine Drugs, 2016, 14(11), 208.

131. Deabes, M.M., Khalil, W.K.B., Attallah, A.G., El-Desouky, T.A., Naguib, K.M.

(2018).Impact of silver nanoparticles on gene expression in Aspergillus flavus

producer aflatoxin B1. Open Access Macedonian Journal of Medical

Sciences, 2018, 6(4), pp. 600–605.

132. Deabes, M.M., Allayeh, A.K., Seif, M.M., Rasmey, A.-H.M., Naguib, K.M.

(2020). Antiviral, antifungal, and antibacterial potential activities of Ephedra Sinica in

Vitro. Jordan J. of Biological ciences, 13(3), pp. 313-320.

133. Deabes, M.M., Aboulthana, W.M., Ahmed, K.A., Naguib, K.M.

(2021). Assessment of the ameliorative effect of Bacillus subtilis against the toxicity

induced by aflatoxin B1 in rats. Egyptian Journal of Chemistry, 64(4), pp. 2141–2164.

134. Deabes, M.M., El-Fatah, S.I.A., Salem, S.H., Naguib, K.M. (2021).

Antimicrobial activity of bioactive compounds extract from Saussurea costus against

food spoilage microorganisms. Egyptian Journal of Chemistry, 2021, 64(6), pp. 2833–

2843.

Patent:

Patent Entitled modified rice straw to remove AFB1 from aquies media 2017.

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