munich, germany 17-21 june 2007ecbo 2007 static depth dependent dispersion compensation in a...

20
17-21 June 2007 ECBO 2007 Munich, Germany Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT system L. Froehly, P. Sandoz, L. Furfaro, M.Ouadour Institut FEMTO-ST; Département d’Optique P.M. Duffieux Besançon, France

Upload: melina-marsh

Post on 14-Jan-2016

220 views

Category:

Documents


3 download

TRANSCRIPT

Page 1: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Static depth dependent dispersion compensation in a real-time static delay line

grating-based correlation OCT system

L. Froehly, P. Sandoz, L. Furfaro, M.Ouadour

Institut FEMTO-ST; Département d’Optique P.M. Duffieux Besançon, France

Page 2: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Dispersion problem in OCT

100m

•Dispersion limits axial resolution

•Dispersion depends on the material thickness

•Dispersion decreases the Signal to Noise ratio

tseS TFenc

j'

12

m1

m13

Page 3: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Hardware correction

S.L.S.

M1

S1O1

O2

Page 4: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Hardware correction (rapid scanning delay line)

K. F. Kwong, D. Yankelevich, K. C. Chu, J. P. Heritage, and A. Dienes, Opt. Lett. 18, 558- (1993) ->first demonstration for pulse measurements

Rollins, S. Yazdanfar, M. Kulkarni, R. Ung-Arunyawee, and J. Izatt, Rollins, S. Yazdanfar, M. Kulkarni, R. Ung-Arunyawee, and J. Izatt, Opt. Express 3, 219-229 (1998)Opt. Express 3, 219-229 (1998)

G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, Opt. Lett. 22, 1811-1813 (1997) ->Application of the system to TD-OCT system

Page 5: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Numerical correction

tIeeI

eItI

dTFjj

jTFd

c

1

•Phase correction in Fourier space•Influence of the phase correction on the image contrast

Quite time consumingQuite time consuming

Page 6: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Grating-based Tomographic system

y

z

S.L.S.

S1M..: MirrorS: Polarizing beam splitterL1: Spherical lensS.L.S. : White light laser sourceC.B. : Polarizing beam splitterD : CCDR : Diffraction grating 530 gr/mmP : prismO… : Miroscope objectivesE : Sample

I(z)

zt

L1

M2

M3C.B.

D

P

O1

O2

R

4

Page 7: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

M3

M2

R

Principle

I

x↔z

Page 8: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

y

z

S.L.S.

S1

I(z)

zt

L1

M2

M3C.B.

D

P

O1

O2

R

4

Absorption

L. Froehly, M. Ouadour, L. Furfaro, P. Sandoz, T. Gharbi et al, Real-time optical coherence spectrotomography : proof of principle volume 6191 of Biophotonics and New Therapy Frontiers. SPIE, Apr. 2006.

Page 9: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

z

z

Optical Depth dependant dispersion compensation

0 200 400 600 800 10000

1000

2000

3000

4000

5000

6000

7000loi de dispersion du réseau

pixels CCD

z

Page 10: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Optical Depth dependant dispersion compensation : principle

Page 11: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Optical Depth dependant dispersion compensation : principle

Page 12: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Optical Depth dependant dispersion compensation : principle

Page 13: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

0 200 400 600 800 10000

1000

2000

3000

4000

5000

6000

7000loi de dispersion du réseau

pixels CCD

Optical Depth dependant dispersion compensation : validation

Page 14: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

0 200 400 600 800 10000

0.5

1

1.5

2

2.5x 10

4 dispersion 2 lames

pixels CCD 0 200 400 600 800 10000

0.5

1

1.5

2

2.5

3

3.5x 10

4 dispersion 1 lame

pixels CCD

Optical Depth dependant dispersion compensation : validation

Page 15: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

0 200 400 600 800 10000

1000

2000

3000

4000

5000

6000

7000loi de dispersion du réseau

pixels CCD

0 200 400 600 800 10000

0.5

1

1.5

2

2.5

3

3.5x 10

4 dispersion 1 lame

pixels CCD

0 200 400 600 800 10000

0.5

1

1.5

2

2.5x 10

4 dispersion 2 lames

pixels CCD

Optical Depth dependant dispersion compensation : validation

Page 16: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

0 200 400 600 800 10000

1000

2000

3000

4000

5000

6000

7000loi de dispersion du réseau

pixels CCD

0 200 400 600 800 10000

1000

2000

3000

4000

5000

6000

7000

pixels CCD

0 200 400 600 800 10000

500

1000

1500

2000

2500

3000

3500

4000

4500

5000

pixels CCD

Optical Depth dependant dispersion compensation : validation

Page 17: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Future directions: lens effect on dispersion

Page 18: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Future directions : lens effect on dispersion

Page 19: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Future directions : catadioptrics systems

y

z

S.L.S.

S1

M2

M3C.B.

P

O1

O2

R

4

D

Page 20: Munich, Germany 17-21 June 2007ECBO 2007 Static depth dependent dispersion compensation in a real-time static delay line grating-based correlation OCT

17-21 June 2007 ECBO 2007 Munich, Germany

Aknowldegments

•French ANR who finances this project•Leukos innovative systems who provide us with microchip-based supercontinuums