19-04-2023

Challenge the future

DelftUniversity ofTechnology

Multifunctional PDMS tips fabricated by polymer casting of KOH etched pyramidal pitsFirst Presentation; Project Defence

Kees Schilder

2Polymer Tip Arrays |

Introduction

• Polymer tip array• Increase of throughput• Challenge is inclination of tip

array• Advantage of PDMS

• Compliance• Stiffness

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Applications

• Proteome analysis

• Cleaning

• Direct write lithography

F. Huo et al., Polymer Pen Lithography, Science (2008)

C. Wingren et al., Progress in miniaturization of protein arrays – a step closer to high-density nanoarrays, Drug

Discovery Today (2007)

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Fabrication Process - Pits

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Fabrication Process - Pits & Holes – 1.1Fabrication Process - Pits & Holes – 1.2

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Fabrication Process - Pits & Holes – 2.1Fabrication Process - Pits & Holes – 2.2Fabrication Process - Pits & Holes – 2.3

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Mask Design

• Simple design• Various configurations

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Timeline - MilestonesWhat has been doneWhat has to be done

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Expected Challenges

• Producing of (very) small tips due to the viscosity of PDMS

• PDMS to SiO2 bonding

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Questions & Discussion