m.sc. semester i physical chemistry paper i (micro wave...
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M.Sc. Semester – I Physical Chemistry
Paper – I
(Micro wave and IR Spectra)
Maximum Marks 50 Lectures : 40
Unit – I :
Basic features of Spectroscopy:
Electromagnetic radiations, Interaction of electromagnetic radiation with matter. Molecular
energy levels. Rotational, vibrational and electronic energy levels. Born Oppenheimer
approximation, Transition probability, transition moment, natural line width, and intensity of
spectral lines. Fourier Transform techniques.
Unit – II :
Rotational Spectra: Rotational modes of a molecule, selection rules for rotational spectra of diatomic molecules
using rigid rotator model, effect of isotopic substitution on the transition frequencies. Non - rigid
rotator. Rotational spectra of polyatomic molecules (Linear, spherical and symmetrical
molecules), Applications.
Unit – III :
Vibrational Spectra:
Vibrational energy of diatomic molecules, vibrational spectra using linear harmonic oscillator
model. Force constant and harmonicity. Theory of vibrational - rotational spectra. P, Q and R
lines in combination spectra. Vibrations of polyatomic molecules. Selection rules, normal modes
of vibration, group frequencies, factors affecting the band position and intensities. Applications,
and interpretation of spectra of simple molecules.
Unit – IV :
Raman Spectra:
Classical and Quantum theory of Raman effect, Pure rotational, vibrational, and vibrational -
rotational Raman spectra. Selection rule. Polarized & depolarized Raman lines, mutual exclusion
principle. Resonance Raman spectra. Applications.
Books Recommended:
1. J. M. Hollas; Modern Spectroscopy, 4th
edition (2004), John Wiley and Sons, Chichester.
2. K. Nakamoto, Infrared and Raman Spectra of Inorganic and Coordination Compounds, 4th
Edn. (1986), John Wiley & Sons, New York.
3. W. Kemp, Organic Spectroscopy, 3rd
Edn. (1991), MacMillan, London.
4. R.M. Silverstein and F.X. Webster, Spectroscopic Identification of Organic Compounds, 6th
Edition (2003) John Wiley, New York.
5. D. L. Pavia, Gary M. Lampman, George S. Kriz; Introduction to Spectroscopy, 3rd
Edition,
(2001), Books / Cole, Thomson Learning.
2
Semester – I M.Sc. Physical Chemistry
Paper - II
(Physical States of Matter and Kinetics)
Maximum Marks 50 Lectures : 40
Unit – I :
Gaseous state: Distribution of molecular velocities. Maxwell - Boltzmann distribution law and its
derivation. Expressions for average, root mean square and most probable velocities with
calculation. Transport properties of gases, diffusion, thermal conductivity and viscosity.
Unit – II :
Solid state: Definition related to crystal structure (symmetry space lattice and space groups),
crystal objects and non - stoichiometry point defects. Non - stoichiometric compounds. Band
theory of solids. Heat capacity of solids (Einstein and Debye theory). Semi conductors, super
conductors, nanomaterials.
Unit – III :
Chemical kinetics: Dynamic chain reaction, H2-Br2; decomposition of ethane and acetaldehyde.
Photochemical combination of H2 - Br2, and H2 - Cl2 reactions. Oscillatory chemical
reactions. Kinetics of enzyme reactions. General features of fast reactions, study of fast
reactions; by flow method, relaxation method, flash photolysis and magnetic resonance
method.
Unit – IV :
Thermodynamics:
Equilibrium thermodynamics (classical), Brief review of laws of thermodynamics.
Partial molar properties, partial molar free energy, partial molor volume and partial molar
enthalpy and their determinations, concept of fugacity and determination of fugacity,
nonideal systems.
Books Recommended:
1. K. J. Laidler, Chemical Kinetics, Third Edition (1987), Harper & Row, New York.
2. P. W. Atkins, Physical Chemistry, Seventh Edition (2002), Oxford University Press, New
York.
3. D.A. Mc Quarrie and J.D. Simon, Physical Chemistry: A Molecular Approach, (1998) Viva
Books, New Delhi.
4. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
3
M.Sc. Semester - I
Practical of Physical Chemistry
Maximum Marks 50 Duration - 4 Hrs.
Any one of the four practicals :
1. Chemical Kinetics: 20 Marks
1. Kinetics of ester hydrolysis in presence of acid.
2. To compare the strength of HCL and H2SO4 by studying the kinetics of hydrolysis of
ethyl acetate.
3. To study the saponification of ethylacetate with NaOH
4. To determine the rate constant of a reaction between acetone & iodine in presence of
mineral acid.
Any one of the three practicals :
2. Surface Tension: 15 Marks To determine the composition of the given solution by drop method by stalagmometre.
3. Viscosity: 15 Marks To determine the composition of a given mixture of two miscible liquids by
Viscometer.
4. Molecular weight determination: 15 Marks
To determine the molecular weight of a given substance by Rast method.
5. Viva-voice 10 Marks
6. Record 5 Marks
Books Recommended:
1. Experiments in Physical Chemistry: J. C. Ghosh, Bharti Bhawan
Publication, Patna.
2. Advanced Experimental Chemistry: Vol. I Physical J. N. Gurtu & R.
Kapoor, S. Chand & Comp.
3. Physical Chemistry Practical: B. D. Khosla (New Delhi)
4. Practical Physical Chemistry: S. R. Palit & S. K. De. Science BookAgency,
Calcutta
4
Semester - II
Paper – I (Physical Chemistry)
(Spectroscopy, X-ray and Electronic Diffraction)
Maximum Marks 50 Lectures : 40
Unit – I :
Electronic Spectra:
Atomic Spectra:
Energies of atomic orbitals, Vector representation of momenta & vector coupling.
Spectra of hydrogen atom and alkali metal atoms.
Unit – II :
Molecular Spectra:
Energy levels in molecules, and molecular orbitals. Principle of electronic spectra of
polyatomic molecules. Emission spectra, photophysical processes in electronically excited
molecules (radioactive and nonradiative), internal conversion. Spectra of transition metal
complexes, charge transfer spectra.
Unit – III :
X - ray Diffraction:
Principle of determination of molecular symmetry and molecular parameter, space
groups and their determination, analysis and assignment of space groups. Structre factor and
its relation to intensity and electron density distribution. Fourier series, Laue patterns,
Weissenberg method, Pattersion method. Difference between neutron and x-ray diffraction.
Unit – IV :
Electron Diffraction:
Principle, experimental techniques, scattering of electrons by gases. Scattering
intensity Versus scattering angles. Weirl equation and radial distribution method for
structural determination of simple gas phase molecules. Low energy electron diffraction
between limitations.
Books Recommended:
1. R. S. Drago, Physical Methods for Chemists, (1992), Saunders College Publishing,
Philadelphia.
2. G. Aruldhas, Molecular Structure and spectroscopy, (2001) Prentice Hall of India Pvt. Ltd.,
New Delhi.
3. C. N. Banwell and E. M. McCash, Fundamentals of Molecular Spectroscopy, 4th
edition
(1994), Tata McGraw Hill, New Delhi.
4. D. H. Williams and Ian Fleming; Spectroscopic Methods in Organic Spectroscopy, (4th
Edition) Tata McGrahill, 1989.
5
Semester - II
Paper - II (Physical Chemistry)
Thermodynamics and Electro Chemistry
Maximum Marks 50 Lectures : 40
Unit – I :
Thermodynamics : Excess function for nonideal solution activity and activity coefficient and their
determination. Thermodynamics of ideal and real gas and gaseous mixtures. Lewis - Randell
rule and its importance. Gibbs – Duhem - margueles equation and its applications.
Unit – II :
Non equilibrium thermodynamics: Thermodynamic criteria for non equilibrium states, entropy production and entropy
flow, fluxes and forces. Phenomenological equations, Onsagar’s reciprocity relations.
Unit – III :
Surface chemistry: Adsorption, surface tension, capillary action, pressure difference across curved
surface (Laplace equation), vapor pressures of droplets (Kelvin equation), Gibbs adsorption
isotherm. Estimation of surface area (BET equation), surface films on liquids, catalytic
activity at surfaces.
Micelles: Surface active agents, classification of surface active agents, critical micellar
concentration (CMC), factors affecting the CMC of surfactants.
Unit – IV :
Electrochemistry: Basic description of ion association, Wein’s effect and Debye - Falkenhagen effect,
effect of ionic strengths on the rate of ionic reaction; primary and secondary salt effects.The
structure of electrical double layer (Helmholtz, Gouy - Chapman and stern model) Butler -
Volmer equation, exchange current density. Tafel plots, polarizable and non -polarizable
interfaces corrosion, types of corrosion, corrosion monitoring and prevention.
Books Recommended:
1. J.O’M. Bockris and A. K. N. Reddy, Modern Electrochemistry, Vol. 2 A & B, Second
Edition (1998), Plenum Press, New York.
2. I.N. Levine, Physical Chemistry, 5th
Edition (2002),Tata McGraw Hill Pub. Co. Ltd., New
Delhi.
3. Y. Moroi; Micelles : Theoretical and Applied Aspects, (1992) Plenum Press, New York.
6
Semester - II
Practical of Physical Chemistry
Maximum Marks 50 Duration - 4 Hrs.
Any one of the two practicals : 20 Marks
1. Distribution Law: a. To determine the distribution coefficient of iodine between water and carbon tetra
chloride.
b. To determine the partition coefficient of benzoic acid between water and benzene.
c. Estimate the molecular weight of benzoic acid in benzene by distributing it between
water & benzene.
2. Colloidal and surface chemistry
a. To determine the adsorption of aqueous acetate acid by activated charcoal and study
the absorption.
b. Preparation of As2O3 and Fe (OH)3 solutions.
Any one of the two practicals : 15 Marks
3. Phase Diagram
a. To draw the phase diagram of the binary system and find the eutectic temperature.
b. To determine the transition temperature of given substance by thermometric method.
4. Solubility
a. To determine the solubility of a salt by gravimetric method.
b. To determine the solubility of an organic acid by titration method.
c. To determine the heat of solution of an organic salt by solubility method.
5. Viva-voice 10 Marks
6. Record 5 Marks
Books Recommended:
1. Experiments in Physical Chemistry: J. C. Ghosh, Bharti Bhawan Publication, Patna.
2. Advanced Experimental Chemistry: Vol. I Physical J. N. Gurtu & R. Kapoor, S.
Chand & Comp.
3. Physical Chemistry Practical: B. D. Khosla (New Delhi)
4. Practical Physical Chemistry: S. R. Palit & S. K. De. Science Book Agency, Calcutta
M.Sc.-III Semester (PHYSICALCHEMISTRY)
PAPER - I (Compulsory) (Spectroscopy and Dispersion Methods in Spectrometry)
Max Marks: 50 Lectures: 40
Unit-I Max Marks 5
Mossbauer Spectroscopy:
Basic principles of Mossbauer spectroscopy, Spectral parameters (isomer shift, quadrupole
interactions and magnetic interactions), Applications of M-B spectra in the study of iron and tin
complexes.
UNIT-II
Mass Spectroscopy:
Introduction, ion production, fragmentation and affecting factors, Molecular ion peak, Meta
stable ion peak, nitrogen rule, cleavage associated with common functional groups. McLafferty
rearrangement, Structural information of organic compounds by interpretation of simple mass
spectra.
UNIT-III
Optical Rotatory Dispersion (ORD):
Linearly and circularly polarized lights, Optical rotatory power, Different types of rotatory
dispersion curves. Application of ORD for the determination of absolute configuration of some
carbonyl compounds.
UNIT-IV
Circular Dichroism (CD): Principle, Definition, Nature of the CD curves, Cotton effect,
Application for the determination of absolute configuration of some carbonyl compounds.
Books Recommended:
1. Spectroscopic Methods in Organic Chemistry: D.H. William & Fleming, Tata McGraw.
2. Spectrometric Identification of Organic Compound: R.M. Silverastein, John Wiley.
3. Modern Spectroscopy: J.M.Hollas, 4th
edition (2004) John Wiley &Sons Ltd, New York.
4. Fundamental of Molecular spectroscopy: C.N.Banwell, 4th
edition (1994) TataMcGrawhill.
5.Physical Methods in Inorganic Chemistry: R.S.Drago, International edition (1971) Affiliated
East West Press, New Delhi.
M.Sc. III Semester (Physical Chemistry)
Paper - II
Thermodynamic (Reversible)
Maximum Marks 75 Duration - 3 hrs
UNIT - I
Thermodynamics of mixture:
Thermodynamics of ideal and real gases and gaseous mixtures. Fugacity of gaseous and
liquid mixtures. Lewis - Randall Rule and its importance.
UNIT - II
Thermodynamics of Solutions:
Thermodynamics of ideal and non - ideal binary solutions, Excess thermodynamics
functions for non - ideal solutions and their determination. Gibbs - Duhem - Margules
equation and its applications. Thermodynamics of polymer solution.
UNIT - III
Thermodynamics of Surfaces:
Thermodynamics of surfaces, Gibb’s adsorption isotherm. Surface films. Applications of
adsorption phenomena. Adsorption indicator and Chromatography.
UNIT - IV
Irreversible Thermodynamics:
Steady state and Cross - phenomena. Stability of steady states. Entropy production in
irreversible processes. Relation between forces and fluxes. Linear phenomenological
relations. Onsagar’s reciprocal Theory. Curie - Prigogine Theorem. Linear
thermodynamics theory of thermo - osmosis and reverse - osmosis.
UNIT - V
Phase Equilibrium:
Thermodynamic interpretation of phase diagram. Phase diagram of two component
systems. Simple eutectic systems (Bi - Co and Fe - C system). Systems exhibiting
complete miscibility in solid and liquid phases. Mixtures having congruent melting
points. Systems having partial miscibility in solid phases. Theory of phase diagram of
(Chloroform - acetic acid - water system and acetone - phenol - water system).
Books Recommended :
1. Samuel Glasstone; Thermodynamics for chemists, East - West Press.
2. J. C. Kuriacose and J. Rajaraman; Thermodynamics (Classical, statistical and
Irreversible), S. Nagin &Co.1986.
3. R. P. Rastogi and R.R.Mishra ; An Introduction to Chemical Thermodynamics, Vikas
Publication,1994..
4. I. Prigogine; Introduction to Thermodynamics of Irreversible processes,Springfield,1955.
5. P. A. Rock; Chemical Thermodynamics, Oxford University Press, 1983.
6. R.Brout; Phase Transitions, Mass Reading, 1965.
7. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
M.Sc. III Semester (Physical Chemistry)
Paper - III
Cells and Electrokinetics
Maximum Marks 75 Duration - 3 hrs
UNIT - I
Conduction in Non - aqueous Media:
Ion association and its effect on conduction. Diffusion of electrolytes. Measurement of
diffusion of coefficient. Diffusion in relation to conductance and viscosity.
UNIT - II
Concentration Cells:
Cells with and without transference, concentration cell involving mixture of
electrolytes. Amalgam cell, liquid Junction potential and its elimination. Membrane
potential and diffusion potential.
UNIT - III
Electro - kinetic phenomena:
Qualitative treatment of electro - osmosis, electrophroesis, streaming potential and
Streaming current. Formation of electrical double layer. Models of electrical double layer
& Zeta potential.
UNIT - IV
Electroanalytical Techniques and Electrodics:
Polarography, Overvoltage, Colorometry and amperometry. Tafel - plots, Butler - Volmer
equation, physical concept of equilibrium exchange current density and over potential.
Unit - V
Corrosion:
The mechanism of corrosion of Metals, corrosion - current and corrosion potential.
Electro - chemical corrosion theory. Estimation of corrosion rates. Corrosion prevention
and electrodeposition.
Books Recommended :
1. J.O’M. Bockris and A. K. N. Reddy, Modern Electrochemistry, Vol. 2 A & B, Second
Edition (1998), Plenum Press, New York.
2. Samuel Glasstone; An Introduction to Electrochemistry, East West Press.
3. P. H. Rieger; Electro Chemistry, 2nd
Edition Chapman & Hall,1988.
4. D.R. Crow; Principles and Application of Electro Chemistry, Chapman and Hall,1988.
5. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
M.Sc. III Semester (Physical Chemistry)
Paper - IV
Quantum Chemistry(Basic)
Maximum Marks 75 Duration - 3 hrs.
UNIT - I
Origin of Quantum Theory:
Planck’s quantum theory of radiation, wave particle duality. Uncertainty principle and
operators.
UNIT - II
Postulates of Quantum Chemistry:
Schrodinger wave equation, physical significance of eigen wave function. Normalized
and orthogonal wave functions. Application of Schrodinger wave equation to simple
systems. Free particle in a box (one dimensional and three dimensional). Harmonic
oscillator, rigid rotator and hydrogen atom. Solution of r, θ and Φ parts. Angular
momentum, & spin, coupling of angular momentum including spin - orbit coupling.
UNIT - III
Approximation Methods:
The perturbation and variation methods and their application to Helium atom exchange
degeneracy electron spin wave function, symmetric and antisymmetric wave function.
Anti symmetry and exclusion principle.Term symbols and spectrographic states.
UNIT - IV Oppenheimer Approximation:
Hydrogen molecule in LCAO - MO and VB treatment of Hydrogen molecule. Idea of self -
consistent field (SCF).
UNIT - V
Huckel - Molecular Orbital Theory:
Huckel pi - electron theory and its applications to the calculations of bond - order,
delocalization energy, electron density to ethylene, butadiene, benzene and cyclobutadiene.
Books Recommended:
1. P. W. Atkins and R. S. Friedman, Molecular Quantum Mechanics, 3rd
edition (1997), Oxford
University Press. Oxford.
3. I. N. Levine, Quantum Chemistry, 5th
edition (2000), Pearson Education, Inc., New Delhi.
2. D. A. McQuarrie and J. D. Simon, Physical Chemistry: A Molecular Approach, (1998) Viva
Books, New Delhi.
4. A. K. Chandra, Introductory Quantum Chemistry, 4th
edition (1994), Tata McGraw Hill, New
Delhi.
5. M. Karplus and R. N. Porter, Atoms and Molecules (1970), Benjamin, London.
7. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
M.Sc. III Semester (Physical Chemistry)
Paper-V
Statistical Thermodynamics (Basic)
Maximum Marks 75 Duration - 3 hrs.
Unit - I
Classical Statistical Mechanics:
Fundamentals of statistical Mechanics, Phase space, Microstates, Microstates’, Ensemble
(canonical and microcanonical), statistical weight factor, probability distribution,
Liouville’s theorem.
Unit - II
Maxwell - Boltzmann distribution law, partition function, separation of partition functions.
Determination of vibrational, translational, rotational and electronic partition functions.
Relationship of partition functions to thermodynamic functions; such as internal energy,
enthalpy, free energy, entropy and chemical potential.
Unit - III
Third law and partition function. Study of monoatomic and diatomic molecule on the basis
of partition function. Sackur - Tetrode equation. Rotational energy and entropy,
vibrational energy and entropy, internal energy and entropy.
Unit - IV
Maxwell Distribution Law:
Maxwell distribution law of velocities from partition function. Average velocity and
average kinetic energy of the molecules. Partition functions for ideal crystals and ideal
gases. Relationship between partition function and equilibrium constant, some numerical
calculations. Ortho and para hydrogen. Heat capacities of solids. Limitations of
Boltzmann statistics.
Unit - V
Quantum Statistics:
Indistinguishability of identical particles. Bose - Einstein statistics and Fermi - Dirac,
Bose - Einstein and Maxwell - Boltzmann statistics. Calculation of Fermi - energy for free
electron in a metal.
Books Recommended:
1. B.K. Agarwal and M. Eisner, Statistical Mechanics, Wiley Eastern, New Delhi, 1988.
2. D.A. McQuarrie, Statistical Mechanics, Harper and Row Publishers, New York, 1976.
3. M.C.Gupta; Statistical Thermodynamics, New Age International, 2000.
4. Chandler; Introduction to Modern Statistical Mechanics, Oxford University Press,1987.
5. S. K. Ma; Statistical Mechanics, World Scientific, Philadelphia 1985.
6. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
7. Benjamin Widom; Statistical Thermodynamics : A Concise Introduction for Chemists,
Cambridge University Press, 1st Edition, 2002.
M.Sc. III Semester Physical Chemistry
Paper -VI
Chemical Kinetics
Maximum Marks 75 Duration - 3 hrs.
Unit - I
Theories of Reaction Rates:
Collision Theory of reaction rates, steric factor. Arrhenius equation and collision
theory. Theory of absolute reaction rates. Thermodynamic formulation of reaction rates,
comparision of Eyring equation and Arrhenius equations. Comparision of transition state
theory and collision theory. Lindemann’s mechanism of unimolecular gaseous reaction.
Unit - II
Fast Reactions and Ionic reactions:
Study of kinetics of fast reactions by stopped - flow technique, relaxation methods and
magnetic resonance methods. Ionic reactions, salt effects (primary and secondary).
Unit - III
Complicating Factors in Reaction Kinetics and Oscillatory Reactions:
Kinetic study of parallel first order and two parallel first order reactions. Reversible or
opposing reactions and consecutive reactions. Oscillatory reactions.
Unit - IV
Nuclear Models and Radioactivity:
The shell model, liquid drop model and the collective model. Radioactive Decay (α and
β). Decay kinetics and radioactive equilibrium (Secular and Transient).
Unit - V
Nuclear Reaction and Nuclear Reactors: Q - values of Nuclear Reactions. Reaction cross - section, Nuclear fission and fusion.
Fission products and fission critical size of thermal reactor. Breeder reactor and
reprocessing of spent fuels.
Unit - VI
Radioactive Technique: Tracer technique, neutron activation analysis, rock - dating, radio carbon dating.
Counting technique such as G. M. counter, ionization counter and proportional counter.
Books Recommended:
1. K. J. Laidler; Chemical Kinetics, 3rd
Edition, Harper and Row,1987.
2. K. A .Connors; Chemical Kinetics, VCH, 1990.
3. Frost & Pearson; Kinetics and Mechanisms, Wiley, 1970.
4. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
5. H. J. Arnikar; Essentials of Nuclear Chemistry, New Age International, rev. 4th
Edition,
2011.
6. G. Fridlander, J.W. Kennedy, E. S. Macias, and J. M. Miller, Nuclear & Radiochemistry, 3rd
Edition (1981), John Wiley, New York.
M.Sc. III Semester Physical Chemistry
Chemistry Practical
Maximum Marks - 150 Duration - 6 hrs
Any One Practical
1) Conductometric titration of a strong acid with a strong base.
2) Conductometric titration of a strong acid with a weak base.
3) Conductometric titration of a strong acid with a strong base.
4) Conductometric titration of a weak acid with a weak base.
5) Conductometric titration of a mixture of a strong acid and a weak acid with a strong base.
Any one Practical
1. To determine the order of saponification of ethyl acetate with NaOH.
2. To find the velocity constant of the hydrolysis of methyl acetate catalyzed by an
acid.
3. Kinetics of iodination of acetone by titrimetry.
Viva -
Record -
Seminar -
M.Sc. SEMESTER FOUR (Nuclear Resonance Spectrometry)
PHYSICAL CHEMISTRY
(Paper I (Compulsory)
Max Marks: 50 Lectures: 40
Unit-I
Nuclear Magnetic Resonance spectroscopy:
Magnetic and non-magnetic nuclei, magnetic moment, nuclear spin, nuclear resonance,
population saturation, shielding of magnetic nuclei, chemical shift and its measurements, factors
affecting coupling constant, use of chemical shifts and spin spin coupling for structural
determination, spin decoupling, chemical exchange, effect of deuteration, nuclear magnetic
double resonance, nuclear over hauser effect (NOE) NMR studies of nuclei other than proton F19
,
P31
.
Unit-II 13
Carbon NMR spectroscopy:
General introduction, Peak assignment, Chemical shift, 13
C-H1 coupling (J Values), application
of 13
C magnetic resonance in structural determination.
Unit-III
Electron spin resonance spectroscopy:
Basic principles, Zero field splitting and Kramer’s degeneracy, factors affecting g-value, isotopic
& anisotopic hyperfine coupling constant. Application of ESR studies.
Unit-IV
Nuclear Quadrupole Resonance spectroscopy:
Quadrupole nuclei, quadrupole moments, electric field gradient, coupling constant, spliting,
Applications.
Books Suggested:
1.Spectroscopic Methods in Organic Chemistry: D.H. William & Fleming, Tata McGraw (2000)
2. Spectrometric Identification of Organic Compound: R.M. Silverastein, John Wiley (2000)
3. Modern Spectroscopy: J.M.Hollas, 4th
edition, John Wiley & Sons Ltd, New York (2004)
4. Fundamental of Molecular spectroscopy: C.N.Banwell, 4th
edition, TataMcGrawhill (1994)
5. Physical Methods in Inorganic Chemistry : R.S.Drago, International edition Affiliated East
West Press, New Delhi (1971)
M.Sc. Final
Semester IV PHYSICAL CHEMISTRY
PAPER - II
Thermodynamics(Irreversible)
Maximum Marks 50 Lectures : 40
UNIT - I
Irreversible Thermodynamics:
Steady state and Cross - phenomena. Stability of steady states. Entropy production in
irreversible processes. Relation between forces and fluxes. Linear phenomenological
relations.
UNIT - II
Onsagar’s reciprocal Theory. Curie - Prigogine Theorem. Linear
thermodynamics theory of thermo - osmosis and reverse - osmosis.
UNIT - III
Phase Equilibrium:
Thermodynamic interpretation of phase diagram. Phase diagram of two component
systems. Simple eutectic systems (Bi - Co and Fe - C system). Systems exhibiting
complete miscibility in solid and liquid phases.
UNIT - IV
Mixtures having congruent melting points. Systems having partial miscibility in solid
phases. Theory of phase diagram of (Chloroform - acetic acid - water system and
acetone - phenol - water system).
Books Recommended :
1. Samuel Glasstone; Thermodynamics for chemists, East - West Press.
2. J. C. Kuriacose and J. Rajaraman; Thermodynamics (Classical, statistical and
Irreversible), S. Nagin &Co.1986.
3. R. P. Rastogi and R.R.Mishra ; An Introduction to Chemical Thermodynamics, Vikas
Publication,1994..
4. I. Prigogine; Introduction to Thermodynamics of Irreversible processes,Springfield,1955.
5. P. A. Rock; Chemical Thermodynamics, Oxford University Press, 1983.
6. R.Brout; Phase Transitions, Mass Reading, 1965.
7. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
M.Sc. Final
Semester IV PHYSICAL CHEMISTRY
PAPER – III
Electrodics
Maximum Marks 50 Lectures : 40
UNIT - I
Electroanalytical Techniques and Electrodics:
Origin of polarography,Interpretation of polarography, Instrumentation, limiting
current, residual and charging current, diffusion current, migration current. Effect of
supporting electrlytes on limiting current. Diffusion coefficint and its evaluation, Iikovic
equation, its derivation and applications. Quasi reversible and irreversible processes.Half
wave potentials and their significance. Polarographic maxima and minima suppressors.
Overvoltage, Colorometry and amperometry.
UNIT - II
Butler - Volmer equation, physical concept of equilibrium exchange current density and
over potential, Tafel – plots.
Unit - III
Corrosion:
The mechanism of corrosion of Metals, corrosion - current and corrosion potential.
Electro - chemical corrosion theory.
UNIT - IV
Kinetics of corrosion:
Estimation of corrosion rates. Corrosion prevention and electrodeposition.
Books Recommended :
1. J.O’M. Bockris and A. K. N. Reddy, Modern Electrochemistry, Vol. 2 A & B, Second
Edition (1998), Plenum Press, New York.
2. Samuel Glasstone; An Introduction to Electrochemistry, East West Press.
3. P. H. Rieger; Electro Chemistry, 2nd
Edition Chapman & Hall,1988.
4. D.R. Crow; Principles and Application of Electro Chemistry, Chapman and Hall,1988.
5. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
M.Sc. Final
Semester IV PHYSICAL CHEMISTRY
PAPER – IV
Quantum Chemistry(Advance)
Maximum Marks 50 Lectures : 40
UNIT - I
Approximation Methods:
The perturbation and variation methods and their application to Helium atom exchange
degeneracy electron spin wave function, symmetric and antisymmetric wave function.
Anti symmetry and exclusion principle.Term symbols and spectrographic states.
UNIT - II
Oppenheimer Approximation:
Hydrogen molecule in LCAO - MO and VB treatment of Hydrogen molecule. Simple
idea of self -consistent field (SCF) with example.
UNIT - III
Huckel - Molecular Orbital Theory:
Huckel pi - electron theory and its applications to the calculations of bond - order,
delocalization energy,
UNIT - IV
Electron density to ethylene, butadiene, benzene and cyclobutadiene.
Books Recommended:
1. P. W. Atkins and R. S. Friedman, Molecular Quantum Mechanics, 3rd
edition (1997), Oxford
University Press. Oxford.
3. I. N. Levine, Quantum Chemistry, 5th
edition (2000), Pearson Education, Inc., New Delhi.
2. D. A. McQuarrie and J. D. Simon, Physical Chemistry: A Molecular Approach, (1998) Viva
Books, New Delhi.
4. A. K. Chandra, Introductory Quantum Chemistry, 4th
edition (1994), Tata McGraw Hill, New
Delhi.
5. M. Karplus and R. N. Porter, Atoms and Molecules (1970), Benjamin, London.
6. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
M.Sc. Final
Semester IV PHYSICAL CHEMISTRY
PAPER – V
Statistical Thermodynamics(Advance)
Maximum Marks 50 Lectures : 40
Unit - I
Maxwell Distribution Law:
Maxwell distribution law of velocities from partition function. Average velocity, root
mean square velocity and most probable velocity. Average kinetic energy of the
molecules. Partition functions for ideal gases.
Unit - II
Relationship between partition function and equilibrium constant, some numerical
calculations. Ortho and para hydrogen. Population ratio determination of deuterium,
nitrogen, and oxygen. Limitations of Boltzmann statistics.
Unit - III
Quantum Statistics:
Indistinguishability of identical particles. Bose - Einstein and Fermi – Dirac statistics.
Comparison among Bose – Einstein, Fermi – Dirac and Maxwell - Boltzmann statistics.
Unit - IV
Partition functions for ideal crystals; Calculation of Fermi - energy for free electron in a
metal. Calculation of heat capacities of solids.
Books Recommended:
1. B.K. Agarwal and M. Eisner, Statistical Mechanics, Wiley Eastern, New Delhi, 1988.
2. D.A. McQuarrie, Statistical Mechanics, Harper and Row Publishers, New York, 1976.
3. M.C.Gupta; Statistical Thermodynamics, New Age International, 2000.
4. Chandler; Introduction to Modern Statistical Mechanics, Oxford University Press,1987.
5. S. K. Ma; Statistical Mechanics, World Scientific, Philadelphia 1985.
6. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
7. Benjamin Widom; Statistical Thermodynamics : A Concise Introduction for Chemists,
Cambridge University Press, 1st Edition, 2002.
M.Sc. Final
Semester IV PHYSICAL CHEMISTRY
PAPER – VI
Nuclear Chemistry
Maximum Marks 50 Lectures : 40
Unit - I
Nuclear Models :
The shell model, liquid drop model and the collective model. Detail study of magic
number nuclei, their stability.
Unit - II
Radioactivity:
Radioactive Decay (α and β). Decay kinetics (consecutive first order and two parallel first
order reactions), and radioactive equilibrium (Secular and Transient).
Unit - III
Nuclear Reaction and Nuclear Reactors: Q - values of Nuclear Reactions. Reaction cross - section, Nuclear fission and fusion.
Fission products and fission critical size of thermal reactor. Breeder reactor and
reprocessing of spent fuels.
Unit - IV
Radioactive Technique: Tracer technique, neutron activation analysis, rock - dating, radio carbon dating.
Counter technique such as G. M. counter, ionization counter and proportional counter.
Books Recommended:
1. K. J. Laidler; Chemical Kinetics, 3rd
Edition, Harper and Row,1987.
2. K. A .Connors; Chemical Kinetics, VCH, 1990.
3. Frost & Pearson; Kinetics and Mechanisms, Wiley, 1970.
4. Thomas Engel, Philip Reid; Physical Chemistry; Pearson Education, 3rd
Edition, 2001.
5. H. J. Arnikar; Essentials of Nuclear Chemistry, New Age International, rev. 4th
Edition,
2011.
6. G. Fridlander, J.W. Kennedy, E. S. Macias, and J. M. Miller, Nuclear & Radiochemistry,
3rd
Edition (1981), John Wiley, New York.
M.Sc. Final
Semester IV
PHYSICALChemistry (Practical)
Maximum Marks - 150 Duration - 6 hrs
Any one Practical 50 Marks.
1. Titration of a strong acid with a strong base pH metrically.
2. Titration of a strong acid with a weak base pH metrically.
3. Titration of a weak acid with a strong base pH metrically.
4. Titration of a mixture of a strong acid and a weak acid with a strong base pH metrically.
Any one Practical 30 Marks.
1. Determination of the enthalpy of ionization of acetic acid.
2. Determination of solubility product of AgCl from E.M.F. measurements.
3. Titration of CH3COOH with NaOH potentiometrically.
Viva - 25 Marks
Record - 15 Marks
Seminar - 30 Marks
M.Sc. Inorganic Chemistry
Paper-III
I semester
(Bonding and Stereochemistry of Transition Metal)
Maximum Marks-50 Lectures- 40
UNIT-I
Stereochemistry and Bonding in Main Group Compounds: VSEPR
Theory,Walsh diagram (tri, tetra and penta atomic molecules), dπ-pπ bonds, bent’s
rule, energetic of hybridization, some simple reactions of covalently bonded
molecules.
UNIT-II
Structures of 2 to 8 coordinate metal complexes: Cation-anion ratio in various
polyhedral, hybrid orbitals and preferred condition of formation of the complexes of
following geometries:
C.N.2-Linear
C.N.3- Trigonal planar, Trigonal pyramidal
C.N.4- Tetrahedral, Square planar
C.N.5- Trigonal bipyramidal, Square pyramidal, pentagonal
UNIT-III
C.N.6- Octahedral, Trigonal prism
C.N.7- Pentagonal bipyramidal, Capped octahedral, Capped trigonal prism
C.N.8- Cubic, Tetragonal antiprismatic, Dodecahedral, Hexagonal bipyramidal and
Bicapped trigonal prism, stereochemical non-rigidity in four to eight coordinate
complexes.
UNIT-IV
Stereoisomerism in six coordinate octahedral complexes (Ma3bcd, Ma2bcde,
Mabcdef and complexes containing bi- and ter- dentate ligands). Intermolecular
and intramolecular rearrangements (Bailar and Ray Dutta Twist only). Mechanism
of racemisation in tris (chelate) octahedral complexes. Methods of resolution of
optical isomers.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W.Portefield, M.A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley; 1984.
6. James E. House; Inorganic Chemistry; 2nd
Edn. Elsevier.
7. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; Wiley.
8. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
9. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
10. R. J. Gillespie and Paul L. A. Popelier; Chemical Bonding and Molecular Geometry; Oxford
University Press (2001).
11. Wai Kee Li, Gong Du Zhou and Thomous Chang Wai Mak; Advance Structural Inorganic
Chemistry; Oxford University Press.
12. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
13. D. F. Shriver and P. W. Atkins; Inorganic Chemistry; 3rd Edn. (1999), ELBS, London.
M.Sc. Inorganic Chemistry
Chemistry Paper-IV
I semester
Chemistry of main group elements
Maximum Marks-50 Lectures- 40
UNIT-I
Bond enthalpy concept and interpretation of the following on the basis of bond
enthalpy data: Thermodynamic stability of XeFn, XeOn; P4 over P2; N2 over N4;
over S2; single bonded structure containing extended arrays of B-O-B of B2O3
molecule; N4O6 over N2O3.
UNIT-II Inorganic solids: Lattice energy and its interpretive uses, explanations for non-
existence of TiCl2, and NH5, stabilization of high oxidation state of metals by
fluorine and oxygen, stabilization of low oxidation states of metals by large anions,
solids electrolytes.
UNIT-III
Preparation, structure, bonding and technical application of
(a) polyether complexes of alkali and alkaline earth metals
(b) thiazyl and its polymers, tetrasulphur dinitride
(c) Polyphasphazenes
UNIT-IV
Polyhedral Boranes: Higher boranes, carboranes, metallo-boranes and metallo-
carboranes –Structure and Bonding in the light of Wade’s and Jemmis Rules. Structure and bonding of
(a) Borane anions
(b) Silicones and silicates
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W.Portefield, M.A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley; 1984.
6. James E. House; Inorganic Chemistry;2nd
Edn, Elsevier.
7. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; John Wiley & Sons, New York.
8. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
9. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
10. Wai Kee Li, Gong Du Zhou and Thomous Chang Wai Mak; Advance Structural Inorganic
Chemistry; Oxford University Press.
11. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Com. (1987), Hong Kong.
12. N. N. Greenwood and A. Earnshaw, Chemistry of the Elements, 2nd Edn. (1997), Butterworth
Heinemann, London.
M.Sc. Inorganic Chemistry
I semester
Practical
Maximum Marks - 50 Duration 5 hrs
Exercise No. 1
Quantitative analysis of an inorganic mixture of seven radicals including Ti, W, Mo, Te, V,
Be, U, Ti, Zr, Th, Ce, and Li Semi micro analysis
Exercise No. 2
Chromatographic separation of the metal ions given in any of the following exercise:
1) Pb+2
, Ag+, Hg2
+2
2) Co+2
, Ni+2
, Cu+2
3) Fe+3
, Cr+3
, Al+3
4) Ba+2
, Sr+2
, Ca+2
Viva
Records
Total Marks
Books Recommended:
1. J. Bassett, R.C. Denney, G.H. Zeffrey and J Mendham;Vogel’s text book of quantitative analysis
2. R. L. Peesok, L. D. Shields, T. Cairns; Modern Methods of Chemical Analysis: 2nd
ed. John Wileys
1997.
M.Sc. Inorganic Chemistry
Paper-III
II semester
Transition Metal Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Kinetic and mechanism of substitution reaction: Nature of substitution reaction,
energy profile of reaction, Kinetics of octahedral, tetrahedral and square planar
complexes in terms of VBT and CFT, inert and labile complexes, acidic hydrolysis,
factors affecting acid hydrolysis, base hydrolysis, conjugate base mechanism, direct
and indirect evidences in favour of conjugate mechanism, anion reaction, reactions
without metal ligand bond cleavage.
UNIT-II
Substitution reactions in square planar complexes, Trans effect, mechanism of the
substitution reactions.
UNIT-III
Redox reaction, Electron transfer reactions, Mechanism of one electron transfer
reactions (inner and outer sphere mechanism), factor affecting the rates of direct
electron transfer reactions, cross reaction and the Mareus-Hash theory, two electron
transfer reactions.
UNIT-IV
Metal ligand equilibrium in solution: Stepwise and overall formation constants
and their relation, trends in stepwise constants, factors affecting the stability of
metal complexes with reference to the nature of metal ion and ligand, chelate effect
and its thermodynamic origin, determination of stability constants by pH metric and
spectroscopic methods.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W.Portefield, M.A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley; 1984.
6. James E. House; Inorganic Chemistry;2nd
, Elsevier.
7. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; Wiley.
8. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
9. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
10. D. F. Shriver and P. W. Atkins; Inorganic Chemistry, 3rd Edn. (1999), ELBS, London.
11. F. A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry,; 6th Edn. (1999), John Wiley &
Sons, New York.
M.Sc. Inorganic Chemistry
Chemistry Paper-IV
II semester
Bonding in Transition Metal
Maximum Marks-50 Lectures- 40
UNIT-I Metal ligands bonding in Transition metal complexes: Crystal field splitting
diagram in tetragonal, square-planar, trigonal bipyramidal and square pyramidal
geometries, limitations of CFT, spectrochemical series, Thermodynamic and
structural effect; site selection in spinels, experimental evidences for metal-ligand
orbital overlap.
UNIT-II
Molecular Symmetry: Symmetry elements, symmetry operations, point group of
molecules, dipole moment, optical activity and its relation with molecular
symmetry.
UNIT-III
Energy levels in an atom; Relation between electronic configuration and energy
terms, Hund’s rules and ground state energy terms, inter electronic repulsion
parameter. Variation of Racah parameter (B and C) in different transition series,
spin orbital coupling parameters.
UNIT-IV
Superconductivity: Zero resistance and transition temperature, superconductivity,
and periodic table, magnetic properties, theory of superconductivity(BSC Theory),
Organic superconductors and high temperature superconductors.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W.Portefield, M.A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley; 1984.
6. James E. House; Inorganic Chemistry;2nd
, Elsevier.
7. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; Wiley.
8. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
9. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
10. David J. Willock; Molecular Symmetry; John Wiley.
11. Yngave Ohrn; Elements of Molecular Symmetry; John Wiley.
12. R. S. Drago; Physical Methods in Inorganic Chemistry; International Edu. (1971), Affiliated East-
West Press, New Delhi.
13. K. Veera Reddy; Symmetry and Spectroscopy of Molecules; New Age International Pvt. Ltd., New
Delhi (1999).
14. F. A. Cotton; Chemical Application of Group Theory; John Wiley.
15. Robert L. Carter; Molecular Symmetry and Group Theory; John Wiley.
16. D. F. Shriver and P. W. Atkins; Inorganic Chemistry, 3rd Edn. (1999), ELBS, London.
M.Sc. Inorganic Chemistry
II semester
Practical
Maximum Marks - 50 Duration 5 hrs
Exercise No. 1
Either both gravimetric or one gravimetric and one volumetric estimation of the ions Ag+,
Cu++, Ni++
, Zn++
, Fe++
, Ba++
, Ca++
Exercise No. 2
Volumetric determination of any one of the following exercise:
1) Chloride and Iodide in admixture
2) Bromide and Iodide in admixture
3) NO3-
by Ce(IV) or MnO4- oxidation
4) Arsenic (III) by BrO3- oxidation
5) Ammonia in an ammonium salt OBr- oxidation
Viva
Records
Total Marks
Books Recommended: 1. J. Bassett, R.C. Denney, G.H. Zeffrey and J Mendham; Vogel’s text book of quantitative analysis
2. R. L. Peesok, L. D. Shields, T. Cairns; Modern Methods of Chemical Analysis: 2nd
ed. John Wileys,
1997.
M.Sc.-III Semester (INORGANIC CHEMISTRY)
PAPER - I (Compulsory) (Spectroscopy and Dispersion Methods in Spectrometry)
Max Marks: 50
Lectures: 40
Unit-I Max
Marks 5
Mossbauer Spectroscopy:
Basic principles of Mossbauer spectroscopy, Spectral parameters (isomer shift, quadrupole
interactions and magnetic interactions), Applications of M-B spectra in the study of iron
and tin complexes.
UNIT-II
Mass Spectroscopy:
Introduction, ion production, fragmentation and affecting factors, Molecular ion peak,
Meta stable ion peak, nitrogen rule, cleavage associated with common functional groups.
McLafferty rearrangement, Structural information of organic compounds by interpretation
of simple mass spectra.
UNIT-III
Optical Rotatory Dispersion (ORD):
Linearly and circularly polarized lights, Optical rotatory power, Different types of rotatory
dispersion curves. Application of ORD for the determination of absolute configuration of
some carbonyl compounds.
UNIT-IV
Circular Dichroism (CD): Principle, Definition, Nature of the CD curves, Cotton effect,
Application for the determination of absolute configuration of some carbonyl compounds.
Books Recommended:
1. Spectroscopic Methods in Organic Chemistry: D.H. William & Fleming, Tata McGraw.
2. Spectrometric Identification of Organic Compound: R.M. Silverastein, John Wiley.
3. Modern Spectroscopy: J.M.Hollas, 4th
edition (2004) John Wiley &Sons Ltd, New York.
4. Fundamental of Molecular spectroscopy: C.N.Banwell, 4th
edition (1994)
TataMcGrawhill.
5. Physical Methods in Inorganic Chemistry: R.S.Drago, International edition (1971)
Affiliated East West Press, New Delhi.
M.Sc. Inorganic Chemistry
Semester III
Paper II
Application of Symmetry and Electronic Spectra
Maximum Marks-50 Lectures -40
UNIT-I
Symmetry species of metal orbital:
Effects of weak crystal fields on free ion terms in octahedral, square planar and
tetrahedral symmetries, Orgel diagrams, mixing of terms, definitions of Dq and
factors affecting in its magnitude, medium and strong field approximation in Oh
point group.
UNIT-II
Transition from weak to strong field and correlation diagram for only d2
case, non
crossing rule,Tanabe Sugano diagrams.
UNIT-III
Electronic spectra of Complexes:
Interpretation of spectra of aqueous solution of [M(H2O)6]n+
, Calculation of Dq, B
and β0 parameters, spectra of spin free and spin paired MA6.
UNIT-IV
Jahn Teller distortion and its effect on electronic spectra.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W.Portefield, M.A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley; 1984.
6. James E. House; Inorganic Chemistry;2nd
, Elsevier.
7. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; Wiley.
8. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
9. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
10. David J. Willock; Molecular Symmetry; John Wiley.
11. Yngave Ohrn; Elements of Molecular Symmetry; John Wiley.
12. R. S. Drago; Physical Methods in Inorganic Chemistry; International Edu. (1971), Affiliated East-
West Press, New Delhi.
13. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
14. K. Veera Reddy; Symmetry and Spectroscopy of Molecules; New Age International Pvt. Ltd., New
Delhi (1999).
15. F. A. Cotton; Chemical Application of Group Theory; John Wiley.
16. Robert L. Carter; Molecular Symmetry and Group Theory; John Wiley.
17. B.N. Figgis; Introduction to Ligand Fields; Wiley Eastern Ltd. New Delhi (1976).
M.Sc. Inorganic Chemistry
Semester III
Paper III
Symmetry and Group Theory
Maximum Marks-50 Lectures -40 UNIT-I
Definition and theorems of group theory, the defining properties of group and group
multiplication tables, cyclic groups, sub groups, classes of operation and their
determination by Similarity transformation and gener rules. Matrix representation
of symmetry elements and point groups, matrices of C3v and C4v point groups,
transformation matrices
UNIT-II
Character table, reducible and irreducible representations. Decomposition of
reducible representation into irreducible ones.
UNIT-III
Projection operations, general theorems of representations, theory and
consequences of the great Orthogonality theorem (derivation not required).
Derivation of character tables for C2v, C3v and C3 point groups, direct products of
representation.
UNIT-IV
Symmetry operation and identification of the point groups of the complex of
following geometries
(a) Octahedral: Ma6, Ma5b, cis and trans Ma4b2, fac and mer-Ma3.
(b) Tetrahedral: Ma4, Ma3b and Ma2b2.
(c) Planar: Ma4, Ma3b, Ma2b2 and Mabcd.
Books Recommended
1. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
2. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
3. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
4. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
5. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
6. R. J. Gillespie and Paul L. A. Popelier; Chemical Bonding and Molecular Geometry; Oxford
University Press (2001).
7. David J. Willock; Molecular Symmetry; John Wiley.
8. Yngave Ohrn; Elements of Molecular Symmetry; John Wiley.
9. R. S. Drago; Physical Methods in Inorganic Chemistry; International Edu. (1971), Affiliated East-
West Press, New Delhi.
10. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
11. K. Veera Reddy; Symmetry and Spectroscopy of Molecules; New Age International Pvt. Ltd., New
Delhi (1999).
12. F. A. Cotton; Chemical Application of Group Theory; John Wiley.
13. Robert L. Carter; Molecular Symmetry and Group Theory; John Wiley.
14. B.N. Figgis; Introduction to Ligand Fields; Wiley Eastern Ltd. New Delhi (1976).
M.Sc. Inorganic Chemistry
Semester III
Paper IV
Organometallic Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Alkyl and aryls of Transition Metals: Types, general synthetic routes, stability
and decomposition pathways.
UNIT-II
Fluxional organometallic compounds: Fluxionality and dynamics equilibria in
compounds such as allyl and dienyl complexes
UNIT-III
Compounds of transition Metal – Carbon Multiple bonds; Low valent carbenes
and carbynes, synthesis, nature of bond and structural characteristics.
UNIT-IV
Transition metal π-complexes:
(a) Preparation, important reactions relating on the ligands, structural features and
bonding of alkenes, alkynes, dienes, dienyls and arene complexes.
(b) Ligands behaviour of C3Ph3+, C4H4
2-, C5H5
- C6H6, C7H7
+ and C8H8
2- in
different Organometallic compounds.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. James E. House; Inorganic Chemistry;2nd
, Elsevier.
5. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
6. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
7. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
8. R. H. Crabtree; The Organometallic Chemistry of Transition Metals; John Wiley.
9. Ch. Elschenbroich and A. Salzer; Organometallics; VCH.
10. J.P. Collman, L.S. Hegedus, J.R. Norton and R.G. Fink; Principles and Applications of
Organotransition metal Chemistry,; Univ. Sci. Books, Mill Valley. California.
11. R. C. Mehrotra and A. Singh; Organometallic Chemistry A unified approach; Wiley Eastern, (1991).
12. E. W. Abel, F. G. A. Stone and G.Wilkinson; Comprehensive Organometallic Chemistry;
Pergamon,1982.
13. K. Nakamoto, Infrared and Raman Spectra of Inorganic and Coordination Compounds, 4th Edn.
(1986), John Wiley & Sons, New York.
M.Sc. Inorganic Chemistry
Semester III
Paper V
Environmental and Bioinorganic Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Scope of essential and Trace Element in Biological systems, Role of metal ions in
Biological processes (Metal binding sites, Metal binding groups, stereochemistry
and oxidation state).
UNIT-II
Nitrogenase: The biochemistry of nitrogen fixation, molybdenum nitrogenase ,
dinitrogen complexes and their reactivity.
UNIT-III
Metal in pollution & medicine: pollution caused by Cd, Hg, & Pb compounds.
UNIT-IV
Metal in medicine; Metal deficiency and diseases, toxic effects of metals, metals
used for diagnosis and chemotherapy with particular reference to anticancer drugs.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
6. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Com. (1987), Hong Kong.
7. M. N. Hughes; Inorganic Chemistry of Biological Processes, 2nd
Edn.(1981), John-Wiley & Sons,
New York.
8. W. Kaim and B. Schwederski; Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life,
An Introduction and Guide; Wiley, New York (1995).
9. S. J. Lippard and J. M. Berg; Principles of Bioinorganic Chemistry; University Science Books
(1994).
10. I. Bertini, H. B. Grey, S. J. Lippard and J. S. Valentine; Bioinorganic Chemistry; Viva Books Pvt.
Ltd. New Delhi (1998)
M.Sc. Inorganic Chemistry
Semester III
Paper VI
Analytical Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Thermal Analysis: Theory, Methodology, Instrumentation and Applications of
Thermo gravimetric analysis (TGA), Differential thermal analysis (DTA),
Differential scanning calorimetry (DSC) and thermometric titrations.
UNIT-II
Theory and instrumentation of polarography. Quantitative applications. Atomic
absorption spectrophotometry, X-ray fluorescence, Flame Photometry, fluorometry,
nephelometry and turbidimetry. UNIT-III
Modern voltametric methods: Samples polarography, pulse polarography, fast
linear sweep polarography, cyclic voltametry, AC polarography and stripping
voltametry.
UNIT-IV
Acid-base Equilibria & Buffer solutions: General concept of acid base
equilibrium water. Determination of PH and PH calculations for aqueous solutions of
weak acid, weak base, salts of weak acid and weak base, Protolysis curve, buffer
and buffer capacity.
Books Recommended
1. James E. House; Inorganic Chemistry;2nd
, Elsevier.
2. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; Wiley.
3. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005)
4. D. A. Skoog and D. N. West; Fundamentals of Analytical Chemistry; 7th
ed.1969.
5. R. L. Peesok, L. D. Shields, T. Cairns; Modern Methods of Chemical Analysis: 2nd
ed. John Wileys
1997.
6. A. l. Vogel.; A Text Book of quantitative Inorganic Analysis;
7. S. M. Khopkar; Analytical Chemistry; 2nd
ed.
M.Sc. Inorganic Chemistry
Semester III
Inorganic Chemistry Practical
Maximum Marks-150 Duration -15 hrs
Exercise No. 1
Preparation of the complex compounds of chromium, manganese, iron,
cobalt, nickel, zinc and copper and their characterization by IR, UV / Vis
spectroscopic techniques.
Exercise No. 2
Synthesis of a series of Ni (II) complexes (with ligands of varying ligand
Field strength), electronic spectral interpretation and calculation of various
ligand-field parameters.
Exercise No. 3
Table work;
Analysis of Electronic Spectra of transition metal complexes at least for one system [dn
(Oh) or (Td)] and calculation of Crystal Field parameters, interelectronic repulsion
parameter and bonding parameter.
Exercise No. 4
Measurement of PH of the solution, simple electrometers titration and calorimetry,
Simple exercises involving chromatographic analysis.
Exercise No. 5
Determination of ferrous ammonium sulfate potentiometrically with standard ceric
sulfate solution (Direct and back titration).
Exercise No. 6
Determination of concentration of halide ion(s) in the given solution
potentiometrically.
Exercise No. 7
Conductometric titration of
(i) strong acid, monobasic weak acid or polybasic weak acid with strong
base
(ii) zinc with EDTA, and
(iii) KCl vs AgNO3
Exercise No. 8
To obtain the protolysis curves involving cases of weak acid, mixture of
acids and polybasic acid employing a pH meter and determine the amount
of the respective acid (in ppm) in the given solution
Viva
Record
Total Marks
Books Recommended:
1. R. L. Peesok, L. D. Shields, T. Cairns; Modern Methods of Chemical Analysis: 2nd
ed. John Wileys
1997.
2. A. l. Vogel; A Text Book of quantitative Inorganic Analysis;
3. S. M. Khopkar ; Analytical Chemistry; 2nd
ed.
4. J. Bassett, R.C. Denney, G.H. Zeffrey and J Mendham;Vogel’s text book of quantitative analysis
M.Sc. SEMESTER FOUR (Nuclear Resonance Spectrometry)
INORGANIC CHEMISTRY
Paper I (Compulsory)
Max Marks: 50 Lectures: 40
Unit-I
Nuclear Magnetic Resonance spectroscopy:
Magnetic and non-magnetic nuclei, magnetic moment, nuclear spin, nuclear resonance,
population saturation, shielding of magnetic nuclei, chemical shift and its measurements,
factors affecting coupling constant, use of chemical shifts and spin spin coupling for
structural determination, spin decoupling, chemical exchange, effect of deuteration, nuclear
magnetic double resonance, nuclear over hauser effect (NOE) NMR studies of nuclei other
than proton F19
, P31
.
Unit-II 13
Carbon NMR spectroscopy:
General introduction, Peak assignment, Chemical shift, 13
C-H1 coupling (J Values),
application of 13
C magnetic resonance in structural determination.
Unit-III
Electron spin resonance spectroscopy:
Basic principles, Zero field splitting and Kramer’s degeneracy, factors affecting g-value,
isotopic & anisotopic hyperfine coupling constant. Application of ESR studies.
Unit-IV
Nuclear Quadrupole Resonance spectroscopy:
Quadrupole nuclei, quadrupole moments, electric field gradient, coupling constant, spliting,
Applications.
Books Suggested:
1. Spectroscopic Methods in Organic Chemistry: D.H. William & Fleming, Tata McGraw
(2000)
2. Spectrometric Identification of Organic Compound: R.M. Silverastein, John Wiley
(2000)
3. Modern Spectroscopy: J.M.Hollas, 4th
edition, John Wiley & Sons Ltd, New York
(2004)
4. Fundamental of Molecular spectroscopy: C.N.Banwell, 4th
edition, TataMcGrawhill
(1994)
5. Physical Methods in Inorganic Chemistry : R.S.Drago, International edition
AffiliatedEast West Press, New Delhi (1971)
M.Sc. Inorganic Chemistry
Semester IV
Paper II
Co-ordination Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Molecular orbital Theory:
symmetry consideration for the formation of σ and π molecular orbitals in Oh
and Td points groups, molecular orbital energy level diagrams of Oh, Td and
Sq planar complexes, discussion of metal ligand interaction.
UNIT-II
Magnetic properties of complexes:
Dia, para, ferro and antiferromagnetism, spin crossover, correlation of magnetic
susceptibility with effective magnetic moment, spin formula, µs+1 formula.
Temperature independent k paramagnetic behaviour. Quenching of orbital
angular momentum by ligand fields. The magnetic properties of complexes with
A, E and T ground terms. Electron delocalization and the magnetic properties of
complexes with A, E and T ground terms.
UNIT-III
Metal clusters and metal-metal bonds:
Condition of formation of metal-metal bond, Metal halide,
carbonyl Clusters and chalcogenide clusters.
UNIT-IV
Parallels between Main Group and Organometallic Chemistry
Isolobal concept (Hoffman) in Organometallic and metal-cluster chemistry.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W.Portefield, M.A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley; 1984.
6. Geoffrey A. Lawrance; Introdution to Coordination Chemistry; Wiley.
7. Catherine E. Housecroft and Alan G. Sharpe; Inorganic Chemistry; 2nd
Edn, Pearson Edu. Ltd.
(2005).
8. James E. House and Kathleen A. House; Descriptive Inorganic Chemistry; 2nd
Edn, Elsevier.(2010).
9. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
10. D. F. Shriver and P. W. Atkins; Inorganic Chemistry, 3rd Edn. (1999), ELBS, London.
11. N. N. Greenwood and A. Earnshaw; Chemistry of the Elements, 2nd Edn. (1997), Butterworth
Heinemann, London.
12. K. Nakamoto; Infrared and Raman Spectra of Inorganic and Coordination Compounds, 4th Edn.
(1986), John Wiley & Sons, New York.
M.Sc. Inorganic Chemistry
Semester IV
Paper III
Molecular Symmetry
Maximum Marks-50 Lectures- 40
UNIT-I
Symmetry aspects of valance bond and molecular orbital theories.
UNIT-II
Application of Symmetry aspects in the formation of AX2 (planer) and AX4
(tetrahedral and square planar) hybrid orbitals.
UNIT-III
Molecular orbital treatment of A2 and AXn (n=1,2 and 3) type molecules. Hückel
molecular orbital treatment of simple and conjugated polyenes.
UNIT-IV
Symmetry treatment and normal modes of vibration: polyatomic molecules of AX2
and AX3 type.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. R. J. Gillespie and Paul L. A. Popelier; Chemical Bonding and Molecular Geometry; Oxford
University Press (2001).
5. David J. Willock; Molecular Symmetry; John Wiley.
6. Yngave Ohrn; Elements of Molecular Symmetry; John Wiley.
7. R. S. Drago; Physical Methods in Inorganic Chemistry; International Edu. (1971), Affiliated East-
West Press, New Delhi.
8. K. Veera Reddy; Symmetry and Spectroscopy of Molecules; New Age International Pvt. Ltd., New
Delhi (1999).
9. F. A. Cotton; Chemical Applications of Group Theory, 3rd Edn. (1999), John Wiley & Sons, New
York
10. Robert L. Carter; Molecular Symmetry and Group Theory; John Wiley & Sons, New York.
M.Sc. Inorganic Chemistry
Semester IV
Paper IV
Bonding and Applications of Organometallic Compounds
Maximum Marks-50 Lectures- 40
UNIT-I
M.O. approach of bonding in ferrocene and bis (benzene) chromium.
UNIT-II
Inorganic π – acid ligands: Transition metal Compounds of dioxygen, dinitrogen
nitrosyl, tertiary phosphine and arsines as ligands.
UNIT-III
Metal carbonyl compounds: Nature of M-C and C-O bonds. Preparation,
properties and structure of platinum metal carbonyls, substitution reactions using
σ-donor, σ-donor & π-acceptor and π-donor ligands.
UNIT-IV
Catalysis involving Organometallic compounds:
Olefin hydrogenation, Oxo reaction, Fischer Tropsch process, Wacker process,
Polymerisation and oligomerisation of olefin and acetylenes
Asymmetric Catalysis: General features of chiral ligands and complexes; Mechanisms
and Catalytic cycles in hydrogenation, isomerization, epoxidation and catalytic
reactions of C-C bond formation.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
5. W.W. Portefield, M. A Reading ; Inorganic Chemistry; A unified Approach; Addison Wesley;
1984.
6. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
7. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Com. (1987), Hong Kong.
8. J.E. Huheey, Keiter and Keiter, Inorganic Chemistry,
9. R. H. Crabtree; The Organometallic Chemistry of Transition Metals; John Wiley.
10. Ch. Elschenbroich and A. Salzer; Organometallics; VCH.
11. J.P. Collman, L.S. Hegedus, J.R. Norton and R.G. Fink; Principles and Applications of
Organotransition metal Chemistry,; Univ. Sci. Books, Mill Valley. California.
12. R. C. Mehrotra and A. Singh; Organometallic Chemistry A unified approach; Wiley Eastern, (1991).
13. K. Nakamoto; Infrared and Raman Spectra of Inorganic and Coordination Compounds; 4th Edn.
(1986), John Wiley & Sons, New York.
M.Sc. Inorganic Chemistry
Semester IV
Paper V
Bioinorganic Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Mechanism of action of the following:
Non-redox metalo enzymes (carboxy peptidase and carbonic anhydrase).
(a) Oxygen carrier and storage proteins (heamoglobin, myoglobin, heamerythrin
and heamocyanins).
UNIT-II
Redox metalo proteins and enzymes: Cytochromes, ruberedoxin ferreodoxins,
copper containing proteins and enzymes with special references to
superoxidedismutase, xanthine oxidase, vitamins B12 & B12 coenzymes.
UNIT-III
Metal ion transport and storage: transferrin, ferritin and bacterical siderophores, Na
and K transport.
UNIT-IV
Photosynthesis: chlorophyll, role of principal photosynthetic pigments, chemistry of
photosynthesis and translocation of foods materials.
Books Recommended
1. F.A. Cotton and G. Wilkinson; Advanced Inorganic Chemistry; 6th Edn. (1999), John Wiley &
Sons, New York.
2. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
3. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
4. Keith F. Purcell and John C. Kotz; Inorganic Chemistry; W. B. Sauders Company (1987), Hong
Kong.
5. W. Kaim and B. Schwederski; Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life,
An Introduction and Guide; Wiley, New York (1995).
6. S. J. Lippard and J. M. Berg; Principles of Bioinorganic Chemistry; University Science Books
(1994).
7. I. Bertini, H. B. Grey, S. J. Lippard and J. S. Valentine; Bioinorganic Chemistry; Viva Books Pvt.
Ltd. New Delhi (1998)
8. J.E. Huheey, Keiter and Keiter, Inorganic Chemistry,
9. M. N. Hughes; Inorganic Chemistry of Biological Processes; 2nd Ed.(1981), John-Wiley & Sons,
New York.
M.Sc. Inorganic Chemistry
Semester IV
Paper VI
Environmental and Analytical Chemistry
Maximum Marks-50 Lectures- 40
UNIT-I
Environment pollution:
Air pollution: general idea of atmosphere and pollutants, green house effect,
primary and secondary pollutants, sources and analysis of CO, SOX, NOX,
hydrocarbons, particulates.
UNIT-II
Water pollutants: sources and their analysis (Pb, As, Cd pesticides and detergent),
water quality parameter’s (DO, BOD, COD, TOC, Total N, Total S, Total P and
Chlorine). Analysis of toxic heavy metals, Cd, Cr, As, Pb, Cu, Separation of Co,
Cu, Mg, Mn, Fe, analysis of SO4-2
, PO43-
, NO3- , NO2
-
UNIT-III
Pesticide, residue analysis soil pollution, Sources of pesticides residue in the
Environment, pesticides degradation by natural forces, effect of pesticide residue on
life, Analytical techniques for pesticides residue analysis.
UNIT-IV Radiation pollution- Classification and effects of radiation, effects of ionizing
radiation on man, Effects of non ionizing radiation on life, radioactivity and
Nuclear fallout, protection and control from radiation.
Books Recommended
1. James E. Huheey; Inorganic Chemistry; 4th Edn. (1993), Addison-Wesley Pub. Co., New York.
2. G. L. Miessler and Donard A. Tarr; Inorganic Chemistry; Pearson Education Ltd.
3. D. Shriver, M. Weller, T. Overton, J. Rourke, F. Amstrong; Inorganic Chemistry; 6th
,W. H. Freenan
and Company.
4. James E. House; Inorganic Chemistry;2nd
, Elsevier.
5. G.W. Vanloon, S.J. Duffer; Environmental Chemistry - A Global Perspective; Oxford University
Press (2000).
6. F.W. Fifield and W. P. J. Hairens; Environmental Analytical Chemistry; 2nd Edition (2000), Black
Well Science Ltd
7. Colin Baird; Environmental Chemistry; W.H. Freeman and Company, New York (1995).
8. A.K. De; Environmental Chemistry; 4th Edition (2000), New Age International Private Ltd., New
Delhi.
9. D.A. Skoog and D.M. West, Fundamental of Analytical Chemistry, International Edition, 7th
Edition
10. (1996), Saunders College Publishing, Philadelphia, Holt, London.
11. R.L. Pecsok, L.D. Shields, T. Cairns and L.C. McWilliam; Modern Methods of Chemical Analysis;
2nd
(1976), John Wiley & Sons, New York.
12. D.A. Skoog; Principles of Instrumental Analysis; 5th Edition (1998), Saunders College of
Publishing, Philadelphia, London.
M.Sc. Inorganic Chemistry
Semester IV
Inorganic Chemistry Practical
Max Marks: 130 + 20=150 12 Hrs
Exercise No. 1
Complete analysis of dolornite cement, brass, stainless-steel, bronze
and white metal.
Exercise No. 2
Estimation of silver, copper, lead, aluminum, manganese, calcium,
chloride ion, oxalate ion.
Exercise No. 3
[At least four exercises, two gravimetric and two volumetric in the
mixed solution].
(i) Cu, Ni, Zn (ii) Ag, Cu, Ni (iii) Cu, Ni, Mg
Exercise No. 4
Photometric Titrations: (a) Cu Vs EDTA (b) Fe Vs EDTA using salicylic
acid
Exercise No. 5
Potentiometric Titrations: (a) FAS vs K2Cr
2O
7 (b) FAS vs. KMnO
4
Exercise No. 6
Conductometric Titrations: (a) NaOH vs. HCl (b) NaOH vs. Boric acid
Viva
Record
Total Marks 130
Seminar 20
Books Recommended:
1. R. L. Peesok, L. D. Shields, T. Cairns; Modern Methods of Chemical Analysis: 2nd
ed. John Wileys
1997.
2. A. l. Vogel; A Text Book of quantitative Inorganic Analysis;
3. S. M. Khopkar ; Analytical Chemistry; 2nd
ed.
4. J. Bassett, R.C. Denney, G.H. Zeffrey and J Mendham;Vogel’s text book of quantitative analysis.
M.Sc. SEMESTER ONE
Paper V Organic Chemistry
(Aromaticity and Reaction Mechanism)
Max Marks: 50 Lectures: 40
Unit I
Aromaticity
Concept of aromaticity and Hückel’s rule, antiaromaticity, non aromaticity, homoaromaticity, aromaticity in
non-benzenoid compounds (tropone, tropolone, azulene, annulene, sydnones, ferrocene and fullerene)
Unit II
Reaction intermediates:
Non classical and bridgehead carbocations, stability and reactions involving non classical and bridge head
carbocations.
Carbenes: Generation, stereochemical consideration, structures and reactions involving carbenes and
carbenoids (Arndt-Eistert reaction)
Nitrenes: Generation, stereochemical consideration and rearrangements (Hoffman Bromamide, Lössen and
Curtius).
Unit III
Aromatic electrophilic reaction
The Arenium ion mechanism (nitration, sulphonation, halogenations, Friedel-Craft alkylation and acylation),
orientation and reactivity in monosubstituted benzene rings, ortho/para ratio, Ipso attack.
Effect of structure on reactivity
Quantitative treatment of reactivity in substrate and electrophiles, Hammett equation and its modification: the
Taft treatment of polar and steric effects in aliphatic compounds).
Unit IV
Aromatic nucleophilic substitution The Aromatic S
N1, S
N2 and benzyne mechanisms. Reactivity – effect of substrate structure, leaving group,
and attacking nucleophile.
Books recommended:
1. M.B. Smith & Jerry March, March’s Advanced Organic Chemistry, 5th
Edition (2001), John Wiley & Sons,
New York.
2. Peter Sykes, A Guide book to Mechanism in Organic Chemistry, 6th
Edition (1997), Orient Longman Ltd.,
New Delhi.
3. S.M. Mukherjee and S.P. Singh, Reaction Mechanism in Organic Chemistry, 1st
Edition (1990), Macmillan
India Ltd., New Delhi.
4. T.H. Lowry and K.S. Richardson, Mechanism and Theory in Organic Chemistry, 3rd
Edition (1998),
Addison – Wesley Longman Inc. (IS Edition)
5. R.T. Morrison and R.N. Boyd, Organic Chemistry, 6th
Edition (2003), Prentice- Hall of India, New Delhi.
6. P.S. Kalsi, Organic Reactions and Their Mechanisms, 1st
Edition (1996), New Age International Pub., New
Delhi.
M.Sc. SEMESTER ONE
Paper VI Organic Chemistry
(Carbohydrates and Natural Products)
Max Marks: 50 Lectures: 40
Unit I
Carbohydrates
Disaccharides (Maltose, Lactose, Sucrose), structure elucidation and its synthesis
Polysaccharides (Starch, Cellulose), structure elucidation
Unit II
Ureides and Purines (Structure determination and its synthesis)
Ureides: Alloxan and Allantoin
Purines: Uric acid, xanthenes bases, caffeine, theobromine, theophynine,
Unit III
Terpenoids
Classification, isoprene rule, general methods for structural determination
Stucture and synthesis of acyclic (citral, geraniol), monocyclic (α-terpineol, carvone, limonene) terpenoids
Unit IV
Molecular recognition and supramolecular chemistry
Molecuar recognition: Definition, complementarity and preorganization, crowns, cryptands and spherands,
molecular recognition with a large ion-dipole component, large ion pairing component, large hydrogen bonding
component, large hydrophobic component (cyclodextrins, cyclophanes)
Supramolecular chemistry: Definition, assembly of complex architectures, self assembly via coordination
compounds, via hydrogen bonding, catenanes, rotaxanes, knots
Books recommended:
1. I. L. Finar, Organic Chemistry, Vol. 2, Pearson India
2. J. Clayden, N. Greeves, S. Warren, P. Wothers, Organic Chemistry, Oxford University Press.
3. K. C. Nicolaou, J. S. Chen, Classics in Total Synthesis III, Wiley-VCH.
4. E. V. Anslyn, D. A. Dougherty, Modern Physical Organic Chemistry, University Science Books.
M.Sc. SEMESTER ONE
PRACTICAL : ORGANIC CHEMISTRY
MAXIMUM MARKS-50 TIME: 5Hrs
1. Separation and identification of Organic mixture (binary)
2. Estimation
Estimation of amino acids
3. Viva-voice
4. Record
Books Suggested:
1. Experiments & Techniques in organic Chemistry: D.Pesto, C.Johnson & M. Miller, Prentice Hall.
2. Micro and macro scale organic experiments: K.I. Iolliamzon & D.C.Heath
3. Vogel’s text book of practical organic Chemistry: A.R.Tatchell, John William.
4. Systematic qualitative analysis organic: H. Middleton and Adward Arnold.
M.Sc. SEMESTER TWO (Reaction Mechanism and Stereochemistry)
Paper V (Organic Chemistry)
Max Marks: 50 Lectures: 40
Unit-I
Nucleophilic aliphatic substitution reaction
Mechanism and stereochemistry of the reactions - SN1, SN
2, SN
i, SN
1’ and SN
2’
Structural and solvent effect on reactivity and rate (effect of R, Nu, Leaving group and solvent).
Addition to carbon-oxygen double bond(C=O), Cram’s rule, Mechanism of Aldol, Perkin, Wittig reaction,
Knoevenagal, Claisen and Cannizzaro reactions.
Unit-II
Elimination Reaction: E1, E2, E1cb, mechanism, stereochemistry and orientation, Saytzeff’s and Hoffmann’s rule.
Elimination vs substitution, Pyrolytic elimination.
Unit-III
Stereochemistry: Elements of symmetry (Alternating axis of symmetry), Enantiotropic, diastereotopic and homotopic groups,
chirality and prochirality, D/L and R/L system, Asymmetric synthesis, Erythreo and Threo isomers,
Interconversion of Fischer,Newmann and Sawhorse projection formula. Theory of racemisation and
resolution, E-Z isomerism in acyclic and cyclic system (C3 to C5).
Unit-IV
Stereochemistry of biphenyl and related compounds. Stereochemistry of biphenyls, allenes and spiranes (configuration, optical activity absolute configuration),
Racemisation of biphenyls. Stereochemistry due to restricted rotation in compounds other than biphenyls.
Molecular overcrowding.
Books suggested:
1. T.H.Lowry & K.S.Richardson: Mechanism and Theory in Organic Chemistry, 3rd
edition (1998)
Addison-Wesley-Longman Inc.
2. March’s Advanced organic chemistry : M. B. Smith and Jerry March, 5th
Edi. (2001) John Wiley &
Sons. New York.
3. Stereochemistry of Organic Compounds: E.L.Eliel and S.H.Wilen, (1994) Wiley Intrescience, New
York.
4. Stereochemistry of Organic Compounds : D.Nasipuri, 2nd
Edition (1994) Wiley Eastern Ltd, New
Delhi.
5. A Guide Book to Mechanism in Organic Chemistry : Peter Sykes, 6th
edition (1997) Orient-Longman
Ltd, New Delhi.
6. Organic Reaction and their Mechanism : P.S.Kalsi, 1st Edition (1996) New Age International Pub.,
New Delhi.
M.Sc. SEMESTER TWO (Natural Product Chemistry)
Paper VI (Organic Chemistry)
Max Marks: 50 Lectures: 40
Unit-I
Alkaloids
General methods for determining structure of Alkaloids
Occurence, Biological importance and chemistry of Quinine and Ephederin.
Unit-II
Occurence, Biological importance and chemistry of Nicotine, Atropine.
Unit-III
Vitamins Structure and physiological function of Vitamin-A and Vitamin-C.
UNIT-IV
Hormones Structure and function of T3, T4 and TSH, Adrenalin.
Books suggested:
1. I.L.Finar: Vol.II, 5th
edition (1975) Longman Ltd, New Delhi.
2. J.W.Apsimon : Total Synthesis of Natural Products,Vol.1-6,Wiley-Interscience
Publications, New York.
3. K.C.Nicolaou:Classics in Total Synthesis of Natural Products,Vol I&II
4. S.V.Bhatt, B.A.Nagasampagi, M.Sevakumar : Chemistry of Natural Products,Springer-2005.
5. G.R.Chatwal: Organic chemistry of Natural Products - Vol II, Himalaya publishing House.
M.Sc. SEMESTER TWO
(Practical Organic Chemistry)
Max Marks: 50 TIME : 5Hrs
Preparation:
1. Preparation of sym-tribromobenzene from aniline.
2. Preparation of 2,4-Dinitrophenyl hydrazine from chlorobenzene
3. Preparation of p-nitro acetanilide from aniline
4. Preparation of p-bromo acetanilide from aniline
5. Preparation benzpinacolone from benzophenone. (Pinacole-Pinacolone rearrangement).
Extraction and Isolation:
1. Extraction of alkaloids from natural sources
2. Isolation of chlorophyll from plant leaves
Viva-voice
Record
Books suggested:
1. Experiments & Techniques in Organic Chemistry: D.Pesto, C.Johnson & M. Miller, Prentice Hall.
2. Micro and Macro Scale Organic Experiments: K.I. Iolliamzon & D.C.Heath.
3. Vogel’s Text Book of Practical Organic Chemistry: A.R.Tatchell, John William.
4. Systematic Qualitative Analysis Organic: H. Middleton and Adward Arnold.
M.Sc. SEMESTER THREE (Spectroscopy and Dispersion Methods in Spectrometry)
Paper I (Compulsory) Organic Chemistry
Max Marks: 50 Lectures: 40
Unit-I Max Marks 5
Mossbauer Spectroscopy:
Basic principles of Mossbauer spectroscopy, Spectral parameters (isomer shift, quadrupole interactions and
magnetic interactions), Applications of M-B spectra in the study of iron and tin complexes.
UNIT-II
Mass Spectroscopy:
Introduction, ion production, fragmentation and affecting factors, Molecular ion peak, Meta stable ion peak,
nitrogen rule, cleavage associated with common functional groups. McLafferty rearrangement, Structural
information of organic compounds by interpretation of simple mass spectra.
UNIT-III
Optical Rotatory Dispersion (ORD):
Linearly and circularly polarized lights, Optical rotatory power, Different types of rotatory dispersion curves.
Application of ORD for the determination of absolute configuration of some carbonyl compounds.
UNIT-IV
Circular Dichroism (CD): Principle, Definition, Nature of the CD curves, Cotton effect, Application for the
determination of absolute configuration of some carbonyl compounds.
Books Recommended:
1. Spectroscopic Methods in Organic Chemistry: D.H. William & Fleming, Tata McGraw.
2. Spectrometric Identification of Organic Compound: R.M. Silverastein, John Wiley.
3. Modern Spectroscopy: J.M.Hollas, 4th
edition (2004) John Wiley &Sons Ltd, New York.
4. Fundamental of Molecular spectroscopy: C.N.Banwell, 4th
edition (1994) TataMcGrawhill.
5.Physical Methods in Inorganic Chemistry: R.S.Drago, International edition (1971) Affiliated East West
Press, New Delhi.
M.Sc. SEMESTER THREE (Protecting Groups and Rearrangement)
ORGANIC CHEMISTRY
Paper II
Max Marks: 50 Lectures: 40
Unit-I
Neighbouring Group Effect
N, S and negatively charged O acting neighbouring group.
Neighbouring group participation by σ and π bonds.
Unit-II
Principle of protection of alcohol, carbonyl and amine group.
Protection of alcohol: Ether, Acetal, Ester protecting group.
Unit-III
Principle of protection of aldehydes and ketones: ketals. acetals, dithio ketals, dithio acetals.
Protection of amines : N-alkyl, N – acyl, N – Silyl, N – Carbamate Protecting Group
Unit-IV
Molecular Rearrangement:
Pinacol-Pinacolone and Wagner-Meerwein rearrangements, Sommelet-Hauser rearrangements,
Beckmann, Benzidine, Dienone-phenol and Fries rearrangement.
Books Suggested:
1. March’s Advanced organic chemistry : M. B. Smith and Jerry March, 5th
Edi. (2001) John Wiley &
Sons New York.
2. Organic Chemistry and acid Base approach: M. B. Smith, 1st Edi. (2011) CRS Press India.
3. A Guide book to mechanism to in organic chemistry : Peter Sykes, 6th
Edi (1997). Orient Longman
Ltd, New Delhi.
4. Organic Synthesis: Disconnection approach, S. Warren (1982) Wiley New York.
5. Organic Chemistry: J. Clayden, N. Greeves, S. Warren and P. Wothers (2001) Oxford Univ. Press
Oxford.
M.Sc. SEMESTER THREE (Reactions and Oxidations)
ORGANIC CHEMISTRY
Paper III
Max Marks: 50 Lectures: 40
Unit-I
Aldol Condensation and related reactions
Aldol reaction, Claisen-Schmidt, Dieckmann, Mannich and Reformatsky reaction. Stobbe and Darzen
reactions.
Unit-II
Oxidation with Chromium and Manganese Compound:
Oxidation of alcohols, aldehydes and C-C double bonds.
Unit-III
Oxidation with Peracids:
Oxidation of carbon-carbon double bonds (sharpless asymmetric epoxidation), carbonyl compounds (Baeyer
Villiger reaction), allylic carbon-hydrogen bonds.
Unit-IV
Other methods of oxidation
Oxidation with periodic acid, lead tetraacetate and selenium dioxide, oppenauer oxidation.
Books Suggested:
1. March’s Advanced organic chemistry: M. B. Smith and Jerry March, 5th
Edi. (2001) John Wiley &
Sons New York.
2. Organic Synthesis: M. B. Smith, (1995) Mc Graw Hill Inc., Newyork.
3. Organic Chemistry: J. Clayden, N. Greeves, S. Warren and P. Wothers 2001 Oxford Univ Press
Oxford.
4. Organic Chemistry : L.G Wade, M.S. Singh: Pearson Edu. 6th
Edi (2011).
5. Organic Chemistry: T. W. G. Solomons, C. B Fryhle, Sasnyder Wiley India Pvt. Ltd. (2015) 11th
Edi.
M.Sc. SEMESTER THREE (Disconnection Approach and Stereo Chemistry)
ORGANIC CHEMISTRY
Paper IV
Max Marks: 50 Lectures: 40
Unit-I
An introduction to synthon and Synthetic equivalents
Unit-II
Functional group interconversions, the importance of the order of events in organic synthesis. One group C-X
and two group disconnections, Chemo selectivity, Reversal of Polarity, Cyclisation reactions, Amine
Synthesis
Unit-III
Conformations:
Conformation and reactivity in cyclohexanes(SN1,SN
2,E1 and E2 reactions).
UNIT-IV
Conformation of decalin and decalol
Books Suggested:
1. March’s Advanced organic chemistry: M. B. Smith and Jerry March, 5th
Edi. (2001) John Wiley &
Sons New York
2. Organic Chemistry: J. Clayden, N. Greeves, S. Warren and P. Wothers (2001) Oxford Univ Press
Oxford.
3. Organic Chemistry and acid Base approach: M. B. Smith, 1st Edi. (2011) CRS Press India.
4. Organic Chemistry: I.L.Finar, Vol.II, 5th
edition (1975) Longman Ltd, New Delhi.
5. Organic Synthesis: Disconnection approach, S. Warren (1982) Wiley New York.
M.Sc. SEMESTER THREE (Terpenoids and Vitamine)
ORGANIC CHEMISTRY
Paper V
Max Marks: 50 Lectures: 40
Unit-I Bicyclic monoterpenoids (α-Pinene, Camphor).
Bicyclic sesquiterpeneoids (α-Cadinene).
Unit-II
Diterpenoids(Abietic acid), Triterpeneoids(squalene).
Unit-III Vitamin B1 and B2, Biotin, Vitamin D
Unit-IV Vitamin E (Tocopherols α, β, γ and δ), Vitamin B6, Biological importance.
Books Suggested:
1. S.W.Pelletier: Chemistry of Alkaloids(1970) Van Nostrand Reinhold Co.,New York.
2. Organic Chemistry. I.L.Finar: Vol.II,5th
edition(1975)Longman Ltd,New Delhi.
3. J.W.Apsimon : Total Synthesis of Natural Products,Vol.1-6,Wiley-Interscience Publications,
New York.
4. K.C.Nicolaou:Classics in Total Synthesis of Natural Products, Vol. I&II.
5. S.V.Bhatt, B.A.Nagasampagi, M.Sevakumar : Chemistry of Natural products,Springer-2005.
6. G.R.Chatwal: Organic chemistry of Natural Products - Vol II, Himalaya publishing House.
M.Sc. SEMESTER THREE (Antibiotics and Insecticides)
ORGANIC CHEMISTRY
Paper VI
Max Marks: 50 Lectures: 40
Unit-I
ANTIBIOTICS:
Definition, classification and importance of antibiotics, PENICILLINES: Introduction, constitution,
Mechanism of action Elementary idea about β-lactam antibiotics. STREPTOMYCIN: Introduction
constitution, mechanism of action. CHLOROAMPHENICOL: chloromycetin (introduction, constitution,
mechanism of action). TETRACYCLINES: Introduction, terramycin (constitution, clinical properties).
Unit-II
INSECTICIDES:
Introduction, Halogenated Insecticides, Elementary idea about (DDT, DDD, DFDT, Perethane, Dilane, BHC,
Chlordane, Heptachlor.
Unit-III
ORGANOPHOSPHORUS: OMPA, Parathion, Paraoxan Insecticides, Diazinon, Malathion : Simple idea.
Unit-IV
HERBICIDES:
A general introduction. 2,4-D and related compounds. Carbamates (aromatic,thiol and sulphonyl).
Organophosphorus herbicides.
Books Suggested :
1. Medicinal Chemistry : A.Burger. Vol.I-III (1995) Wiley Interscience Publications,New York.
2. Principle of Medicinal Chemistry :W.O.Foye, 3rd Edition(1989), Lea & Febiger/Varghese Publishing
House, Bombay
3. The Organic Chemistry of Drug Synthesis :D.Lednicer and L.A.Mitscher, Vol.I-III, Wiley
Interscience.
4. Medicinal Chemistry : A.Kar (1993) Wiley Eastern Ltd, New Delhi.
5. I.L.Finar: Vol.II, 5th
edition (1975) Longman Ltd,New Delhi.
M.Sc. SEMESTER THREE (Organic Chemistry Practical)
Max Marks: 150 Duration: 6 hours
1. Separation and identification of organic mixture containing upto three components.
2. Estimation of N, S and halogens.
Viva
Record
Total Marks 150
Note: There will be a board of two examiners in M.Sc.III semester examination for each branch. The external
examiner of the board will be of same branch from outside and the internal examiner of the same branch will
be from the college where the practical examination will be conducted.
M.Sc. SEMESTER FOUR (Nuclear Resonance Spectrometry)
ORGANIC CHEMISTRY
Paper I (Compulsory)
Max Marks: 50 Lectures: 40
Unit-I
Nuclear Magnetic Resonance spectroscopy:
Magnetic and non-magnetic nuclei, magnetic moment, nuclear spin, nuclear resonance, population saturation,
shielding of magnetic nuclei, chemical shift and its measurements, factors affecting coupling constant, use of
chemical shifts and spin spin coupling for structural determination, spin decoupling, chemical exchange, effect
of deuteration, nuclear magnetic double resonance, nuclear over hauser effect (NOE) NMR studies of nuclei
other than proton F19
, P31
.
Unit-II 13
Carbon NMR spectroscopy:
General introduction, Peak assignment, Chemical shift, 13
C-H1 coupling (J Values), application of
13C
magnetic resonance in structural determination.
Unit-III
Electron spin resonance spectroscopy:
Basic principles, Zero field splitting and Kramer’s degeneracy, factors affecting g-value, isotopic & anisotopic
hyperfine coupling constant. Application of ESR studies.
Unit-IV
Nuclear Quadrupole Resonance spectroscopy:
Quadrupole nuclei, quadrupole moments, electric field gradient, coupling constant, spliting, Applications.
Books Suggested:
1.Spectroscopic Methods in Organic Chemistry: D.H. William & Fleming, Tata McGraw (2000)
2. Spectrometric Identification of Organic Compound: R.M. Silverastein, John Wiley (2000)
3. Modern Spectroscopy: J.M.Hollas, 4th
edition, John Wiley & Sons Ltd, New York (2004)
4. Fundamental of Molecular spectroscopy: C.N.Banwell, 4th
edition, TataMcGrawhill (1994)
5. Physical Methods in Inorganic Chemistry : R.S.Drago, International edition Affiliated East West Press,
New Delhi (1971)
M.Sc. SEMESTER FOUR (Pericyclic Reactions and Photochemistry)
ORGANIC CHEMISTRY
Paper II
Max Marks: 50 Lectures: 40
Pericyclic Reactions:
Unit-I
Symmetry properties of molecular orbitals, Woodward-Hofmann rule, Electrocyclic reactions (cyclobutene-
butadiene and cyclohexadiene-hexatriene interconversions).
Unit-II
1. Cycloaddition reactions [2+2] and [4+2].
2. Sigmatropic rearrangements [1,3],[1,5] and [3,3], Claisen and Cope rearrangements.
3. Analysis of these reaction by correlation diagram, FMO and PMO methods.
Unit-III
Principles of photochemistry (Photochemical energy, electronic excitation, excited states, energy transfer).
Photochemistry of carbonyl compounds ( Photoreduction, Norrish type I & II reactions, Paterno Buchi
reactions.).
Unit-IV
Photochemistry of Olefins(cis-trans isomerisation of butadiene). Photochemistry of arenes.
Photorearrangement of cyclohexadienones, di-pi methane rearrangement.
Books Suggested:
1. March’s Advanced organic chemistry: M. B. Smith and Jerry March, 5th
Edi.(2001) John Wiley &
Sons New York .
2. Pericyclic Reactions:S.M.Mukherjee and S.P.Singh,MacMillan India,New Delhi.
3. Pericyclic Reactions : I.Fleming (1999) Oxford University Press, Oxford.
4. Aspects of Organic Photochemistry : W.M.Horspool, Academic Press, New York.
5. Introduction to Organic Photochemistry : J.D.Coyle, Wiley-Blackwell(1986).
6. Molecular Reactions and Photochemistry : C.H.Depuy and O.L.Chapman, 2nd
edition (1988) Prentice
Hall,New Delhi.
7. Photochemistry: C.E.Wayne and R.P.Wayne, Oxford Chemistry (1996) Primers.
M.Sc. SEMESTER FOUR (Reagents and Name Reactions)
ORGANIC CHEMISTRY
Paper III
Max Marks: 50 Lectures: 40
Unit-I
CATALYTIC HYDROGENATION: Reduction of functional groups,mechanism and stereochemistry.
Homogeneous Hydrogenation[Hydrogen transfer (Wilkinson’s catalyst) and hydride transfer].
Unit-II
METAL HYDRIDE REDUCTIONS: ( LiAlH4,NaBH4) Reduction of aldehydes,ketones and other
functional groups,stereochemistry of ketone reduction ,Hydroboration reactions.
REDUCTION BY DISSOLVING METALS : Clemmensen and Birch reduction.
REDUCTION WITH HYDRAZINES: Wolf-Kishner reduction.
REDUCTION WITH ALKOXIDE: Meerwein-Ponndrof-Verley reduction
Unit-III
SELECTIVE ORGANIC NAME REACTIONS: Favorskii reaction, Ene reaction, Stork-enamine
reaction, Shapiro reaction, Woodward and Prevost hydroxylation, Peterson synthesis, Hofmann-Loffler-
Freytag reaction
Unit-IV
REAGENTS IN ORGANIC SYNTHESIS : Use of following reagents in organic synthesis and
functional group transformation, Gilman reagent(Lithium dialkyl copper). Lithium diisopropyl amide(LDA)
,Dicyclohexyl Carbodiimide (DCC),1,3-Dithiane(reactivity umpolung) Trimethylsilyliodide ,Tri-n-buty tin
hydride ,DDQ, Phase Transfer catalyst, Crown ethers ,Merrifield resin, Heck reaction, Suzuki Coupling
,Mukaiyama reaction
Books Suggested:
1.March’s Advanced organic chemistry : M. B. Smith and Jerry March, 5th
Edi. 2001 John Wiley & Sons
Newyork
2.Organic Chemistry and acid Base approach: M. B. Smith, 1st Edi 2011 CRS Press India.
3.Modern Synthetic Reactions:H.O.House,2nd
Edition(1972),Benjamin/Cummings Publishing
Company,Californaia.
4. Organic Chemistry: J. Clayden, N. Greeves, S. Warren and P. Wothers 2001 Oxford Univ Press Oxford.
5.Organometallic reagents in Synthesis:P.R.Jenkins(1992) Oxford University Press,
M.Sc. SEMESTER FOUR (Free Radicals, Heterocyclic Chemistry and Spectroscopy)
ORGANIC CHEMISTRY
Paper IV
Max Marks: 50 Lectures: 40
Unit-I :
FREE RADICALS: Generation,structure and stability,Radical effect. Reactions [fragmentation,
substitution,Addition and Oxidation].
HETEROCYCLIC COMPOUNDS:
Unit-II :
Nomenclature of heterocyclic compounds containg one,two and three Hetero atoms. Chemistry of- Three
membered ring- Aziridines and Four membered ring- Azetidines
Unit-III:
Chemistry of -Five membered ring (AZOLES),pyrazole, Imidazole, Oxazole and Thiazole.
Six membered ring(DIAZINE GROUP),Pyrimidine.
Unit-IV
SPECTROSCOPY:
Applications of UV,IR,NMR and Mass spectrometry in elucidation of structures of organic compounds.
Books Suggested:
1. T.L.Gilchrist:Heterocyclic Chemistry,3rd
edition(1997),Addison-Wesley Longman Ltd.,England
2. R.K.Bansal:Heterocyclic Chemistry;Synthesis,Reactions and Mechanism,3rd
edition(1999),New Age
International Publisher,New Delhi
3.A.R.Katritzky and A.F.Pozharskii:Handbook of Heterocyclic Chemistry,2nd
Edition(2000),Pergamon
Press,Oxford.
4.T.H.Lowry & K.S.Richardson:Mechanism and Theory in Organic Chemistry,3rd
edition,(1998),Addison-
Wesley-Longman Inc
M.Sc. SEMESTER FOUR (Steroids and Natural Products)
ORGANIC CHEMISTRY
Paper V
Max Marks: 50 Lectures: 40
Unit-I :
STEROIDS: Diel’s Hydrocarbon,Cholesterol
Unit-II :
SEX HORMONES: Oestrone,testosterone ,progesterone,cortisone
Unit-III :
NATURAL PIGMENTS: General nature and classification.Carotenoids( β-carotene).Anthocyanidins and
Anthocyanins(Cyanidin,Cyanin). Flavones and Flavonols (Flavone,Flavonol &Quercitin).
Unit-IV :
ALKALOIDS: Opium alkaloids(Morphine).Rauwolfia alkaloids(Reserpine), Coca alkaloids(Cocaine).
Books Suggested:
1. S.W.Pelletier:Chemistry of Alkaloids,(1970)Van Nostrand Reinhold Co.,New York. Organic
Chemistry.
2. I.L.Finar: Vol.II,5th
edition(1975)Longman Ltd,New Delhi.
3. J.W.Apsimon:Total Synthesis of Natural Products,Vol.1-6,Wiley-Interscience Publications,New York.
4. K.C.Nicolaou:Classics in Total Synthesis of Natural Products,Vol I&II
5. S.V.Bhatt,B.A.Nagasampagi,M.Sevakumar:Chemistry of Natural products,Springer-2005.
6. G.R.Chatwal: Organic chemistry of Natural Products-Vol II,Himalaya publishing House
M.Sc. SEMESTER FOUR (Medicinal Chemistry)
ORGANIC CHEMISTRY
Paper VI
Max Marks: 50 Lectures: 40
DRUGS :
Unit-I :
Introduction,characteristics of drug, classification of drugs. ANTIMALARIALS: Pamaquine, quinacrine,
chlroquine, poludrine, Santoquine: Simple idea. ANTICANCER AGENTS: Introduction, Chemotherapy of
cancer, alkylating agents, Antimetabolites.
Unit-II :
ANTITUBERCULAR AGENTS: Cycloserine, ethambutol: Simple idea. ANTIBACTERIALS: sulpha drugs
(sulphanilamide, sulphapyridine, sulphathiazole, sulphadiazine,, sulphaguanidine, prontosil), Simple idea.
Unit-III:
FUNGICIDES: Definition. protectant fungicides.DITHIOCARBAMATES AND RELATED COMPOUNDS:
Thiram, Ziram, Ferbam, Nabam, Zineb-Maneb. HALOGENATED PHENOLS: Pentachlorophenol,
dichlorophen. QUINONES: Dichlone, Chloranil
Unit-IV :
RODENTICIDES: SYNTHETIC ORGANIC RODENTICIDES: ANTU,Warfarin,Coumochlor,
Dicoumarin
Books Suggested :
1. Medicinal Chemistry : A.Burger.vol.I-III(1995)Wiley Interscience Publications,New York.
2. Principle of Medicinal Chemistry :W.O.Foye, 3Edition(1989),Lea&Febiger/Varghese Publishing
House,Bombay
3. The organic Chemistry of Drug Synthesis :D.lednicer and L.A.Mitscher,Vol.I-III,Wiley Interscience.
4. Medicinal Chemistry : A.Kar(1993)Wiley Eastern Ltd,New Delhi
5. .I.L.Finar: Vol.II,5th
edition(1975)Longman Ltd,New Delhi.
M.Sc. SEMESTER FOUR
ORGANIC CHEMISTRY (Practical)
Max Marks: 130 + 20=150 12 Hrs
Ques 1. Preparion of compounds involving not more than three stages.
Ques 2. Simple experiments on paper or thin layer chromatography.
OR
Interpretation of IR and PMR spectra of simple organic compound, hydrocarbons, carbonyl compounds,
hydroxyl compounds amines, acids and derivatives.
Interpretation of IR Spectra of synthesized compound in the lab.
Viva
Record
Total Marks
Seminar 20
Note: There will be a board of two examiners in M.Sc.Final examination for each branch. The external
examiner of the board will be of same branch from outside and the internal examiner of the same branch will be
from the college where the practical examination will be conducted.