microbiology the science

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10- The use of microbes in the antibiotic industry:  Antibiotic is a substance produced by a microorganism that is effective in killing or inhibiting the growth of other organism. * certain bacteria and fungi produce antibiotic that are used to treat patient with infectious diseases.

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Page 1: Microbiology the Science

8/3/2019 Microbiology the Science

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10- The use of microbes in the antibiotic

industry: Antibiotic is a substance produced by a

microorganism that is effective in killing or

inhibiting the growth of other organism.

* certain bacteria and fungi produce antibioticthat are used to treat patient with infectiousdiseases.

Page 2: Microbiology the Science

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11- Microbes are essential in the field ofgenetic engineering:

Genetic engineering: a science in which agenefrom organism ( bacteria, human, an animal, or

plant) is inserted into bacteria or yeast cell toget benefit, the cell that receive the new genecan now produce whatever product is coded

for by the gene. 

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e.g Production of insulin, various type of

growth hormones, vaccines…..by geneticengendered bacteria and yeast.

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Page 5: Microbiology the Science

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12-Studying purposes : microbes have

been used as (a cell model), more learned

about the structure and functions ofmicrobial cells , more learned about cellsin general

 e.g usage of Escherichia. coli (E.coli) as astudy model.

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13- finally we come to diseases : Microorganisms cause two categories of disease

 

A-infectious disease: result when a pathogenscolonizes the body and subsequently causedisease.B- microbial intoxication: results when person

ingests a toxin ( poisonous substance) that hasbeen produced by a microorganisms) .

 

*Infectious diseases: are the leading cause ofdeath in the world, and the third leading cause ofdeath in USA after heart and cancer.

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Any one pursuing a career in a healthcareprofession must be aware :

 1- infectious diseases2- the pathogens that causes them3- the source of the pathogens

4- how the diseases transmitted5- how to protect yourself and you patient from

these disease

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Careers In MicrobiologyA microbiologist: is a scientist who study tiny

organisms called microorganismswithin the science of microbiology there aremany career fieldse.g a person may specialize in the study of just one

particular category of microorganisms:- bacteriologist: specialized in study of bacteria- phycologists: study of algae- protozoologists: study of protozoan- mycologists: study of fungi- virologists: study of fungi

 

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Other career fields in microbiology pertainmore to applied microbiology:

- Agriculture microbiology.- Biotechnology (industrial microbiology).- Environmental microbiology andbioremediation.

- Medical and clinical microbiology.- Microbial genetics and genetic engineering.- Paleomicrobilogy: study of ancient microbes- Parasitology

- veterinary microbiology 

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Pioneers in the Science of Microbiology

*bacteria and protozoa were the first microorganisms

to be observed by humans.

*Among the most significant events in the earlyhistory of microbiology were:

- development of microscope- bacterial staining procedure- technique that enabled microorganisms to becultured in the laboratory

- steps could be taken to prove that specificmicroorganisms were responsible for specificinfectious disease 

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Among the individuals who contributed to our

present understanding of microorganisms: 

1- Anton van leeuwenhoek ( father of microbiology)and the father of protozoology)

he create what today are known as a single-lensmicroscopeshe used his microscope to examine almost anythinghe could get his hand on: scraping from his teeth,

water, blood, sperm, and even diarrheal stool. 

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2- Louis Pasteur : French chemist, made numerous

contributions to microbiology:

-discovered what occurs during alcoholic fermentation-ending the theory of spontaneous generation-discovered exist of aerobes and anaerobes organisms- developed what known as pasteurization- discovered the infectious agents of silkworm disease-contribute to germ theory of disease (specificmicroorganisms cause specific infectious diseasee.g Bacillus anthracis cause anthrax 

- championed changes in hospital practices to minimize the 

spread of disease by pathogens - developed vaccines to prevent cholera, anthrax…...

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3-Robert koch (German Physician) :

- develop the germ theory- discovered that bacillus anthracis produce spores,capable of resisting adverse conditions.

- developed methods of fixing, staining, ad photographingbacteria.

-developed methods of cultivating bacteria on solid media- discovered bacterium Mycobacterium tuberculosis thatcauses tuberculosis and Vibrio cholerae that causecholera -work on tuberculin ( a proetin derived from

M.tuberculosis) which lead to the development of a skinvaluable in diagnosing tuberculosis.